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Items: 1 to 50 of 111

1.

A brief review on the strategy of developing SPR-based biosensors for application to the diagnosis of neglected tropical diseases.

Souto DEP, Volpe J, Gonçalves CC, Ramos CHI, Kubota LT.

Talanta. 2019 Dec 1;205:120122. doi: 10.1016/j.talanta.2019.120122. Epub 2019 Jul 11.

PMID:
31450437
2.

Optimization of a Methodology for Quantification and Removal of Zinc Gives Insights Into the Effect of This Metal on the Stability and Function of the Zinc-Binding Co-chaperone Ydj1.

de Jesus JR, Aragão AZB, Arruda MAZ, Ramos CHI.

Front Chem. 2019 Jun 11;7:416. doi: 10.3389/fchem.2019.00416. eCollection 2019.

3.

Solution NMR investigation on the structure and function of the isolated J-domain from Sis1: Evidence of transient inter-domain interactions in the full-length protein.

Pinheiro GMS, Amorim GC, Iqbal A, Almeida FCL, Ramos CHI.

Arch Biochem Biophys. 2019 Jul 15;669:71-79. doi: 10.1016/j.abb.2019.05.020. Epub 2019 May 26.

PMID:
31141701
4.

Thermodynamic analysis of interactions of the Hsp90 with adenosine nucleotides: A comparative perspective.

Minari K, de Azevedo ÉC, Kiraly VTR, Batista FAH, de Moraes FR, de Melo FA, Nascimento AS, Gava LM, Ramos CHI, Borges JC.

Int J Biol Macromol. 2019 Jun 1;130:125-138. doi: 10.1016/j.ijbiomac.2019.02.116. Epub 2019 Feb 20.

PMID:
30797004
5.

Studies on the effect of the J-domain on the substrate binding domain (SBD) of Hsp70 using a chimeric human J-SBD polypeptide.

Tiroli-Cepeda AO, Seraphim TV, Pinheiro GMS, Souto DEP, Kubota LT, Borges JC, Barbosa LRS, Ramos CHI.

Int J Biol Macromol. 2019 Mar 1;124:111-120. doi: 10.1016/j.ijbiomac.2018.11.130. Epub 2018 Nov 17.

PMID:
30458192
6.

Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death.

Wong KS, Mabanglo MF, Seraphim TV, Mollica A, Mao YQ, Rizzolo K, Leung E, Moutaoufik MT, Hoell L, Phanse S, Goodreid J, Barbosa LRS, Ramos CHI, Babu M, Mennella V, Batey RA, Schimmer AD, Houry WA.

Cell Chem Biol. 2018 Aug 16;25(8):1017-1030.e9. doi: 10.1016/j.chembiol.2018.05.014. Epub 2018 Jun 28.

7.

MEASURING THE DISTANCE BETWEEN STERNOCLAVICULAR JOINT AND HILAR STRUCTURES WITH TOMOGRAPHY.

Sola WC JUNIOR, Colferai TA, Ramos CH, Santos PSD, Gerlack JS, Gomes AF.

Acta Ortop Bras. 2018 May-Jun;26(3):187-190. doi: 10.1590/1413-785220182603152655.

8.
9.

1H, 15N and 13C resonance assignments of the J-domain of co-chaperone Sis1 from Saccharomyces cerevisiae.

Pinheiro GMS, Amorim GC, Iqbal A, Ramos CHI, Almeida FCL.

Biomol NMR Assign. 2018 Oct;12(2):279-281. doi: 10.1007/s12104-018-9823-6. Epub 2018 Apr 30.

PMID:
29713947
10.

Revealing the interaction mode of the highly flexible Sorghum bicolor Hsp70/Hsp90 organizing protein (Hop): A conserved carboxylate clamp confers high affinity binding to Hsp90.

Adão R, Zanphorlin LM, Lima TB, Sriranganadane D, Dahlström KM, Pinheiro GMS, Gozzo FC, Barbosa LRS, Ramos CHI.

J Proteomics. 2019 Jan 16;191:191-201. doi: 10.1016/j.jprot.2018.02.007. Epub 2018 Feb 6.

PMID:
29425735
11.

Hsp78 (78 kDa Heat Shock Protein), a Representative AAA Family Member Found in the Mitochondrial Matrix of Saccharomyces cerevisiae.

Abrahão J, Mokry DZ, Ramos CHI.

Front Mol Biosci. 2017 Aug 23;4:60. doi: 10.3389/fmolb.2017.00060. eCollection 2017. Review.

12.

Biomechanical evaluation of the long head of the biceps brachii tendon fixed by three techniques: a sheep model.

Ramos CH, Coelho JC.

Rev Bras Ortop. 2016 Dec 30;52(1):52-60. doi: 10.1016/j.rboe.2016.12.008. eCollection 2017 Jan-Feb.

13.

Risk factors for glenoid erosion in patients with shoulder hemiarthroplasty: an analysis of 118 cases.

Herschel R, Wieser K, Morrey ME, Ramos CH, Gerber C, Meyer DC.

J Shoulder Elbow Surg. 2017 Feb;26(2):246-252. doi: 10.1016/j.jse.2016.06.004. Epub 2016 Aug 18.

PMID:
27545049
14.

Heat Shock Protein 90 kDa (Hsp90) Has a Second Functional Interaction Site with the Mitochondrial Import Receptor Tom70.

Zanphorlin LM, Lima TB, Wong MJ, Balbuena TS, Minetti CA, Remeta DP, Young JC, Barbosa LR, Gozzo FC, Ramos CH.

J Biol Chem. 2016 Sep 2;291(36):18620-31. doi: 10.1074/jbc.M115.710137. Epub 2016 Jul 8.

15.

Low sequence identity but high structural and functional conservation: The case of Hsp70/Hsp90 organizing protein (Hop/Sti1) of Leishmania braziliensis.

Batista FAH, Seraphim TV, Santos CA, Gonzaga MR, Barbosa LRS, Ramos CHI, Borges JC.

Arch Biochem Biophys. 2016 Jun 15;600:12-22. doi: 10.1016/j.abb.2016.04.008. Epub 2016 Apr 19.

PMID:
27103305
16.
17.

Disaggregases, molecular chaperones that resolubilize protein aggregates.

Mokry DZ, Abrahão J, Ramos CH.

An Acad Bras Cienc. 2015 Aug;87(2 Suppl):1273-92. doi: 10.1590/0001-3765201520140671. Epub 2015 Aug 25. Review.

18.

From Conformation to Interaction: Techniques to Explore the Hsp70/Hsp90 Network.

Batista FA, Gava LM, Pinheiro GM, Ramos CH, Borges JC.

Curr Protein Pept Sci. 2015;16(8):735-53. Review.

PMID:
25961397
19.

Corrigendum: αB-crystallin interacts with and prevents stress-activated proteolysis of focal adhesion kinase by calpain in cardiomyocytes.

Pereira MB, Santos AM, Gonçalves DC, Cardoso AC, Consonni SR, Gozzo FC, Oliveira PS, Pereira AH, Figueiredo AR, Tiroli-Cepeda AO, Ramos CH, de Thomaz AA, Cesar CL, Franchini KG.

Nat Commun. 2015 Mar 23;6:6508. doi: 10.1038/ncomms7508. No abstract available.

PMID:
25799360
20.

Human mitochondrial Hsp70 (mortalin): shedding light on ATPase activity, interaction with adenosine nucleotides, solution structure and domain organization.

Dores-Silva PR, Barbosa LR, Ramos CH, Borges JC.

PLoS One. 2015 Jan 23;10(1):e0117170. doi: 10.1371/journal.pone.0117170. eCollection 2015.

21.

Specification of Hsp70 function by Type I and Type II Hsp40.

Cyr DM, Ramos CH.

Subcell Biochem. 2015;78:91-102. doi: 10.1007/978-3-319-11731-7_4. Review.

PMID:
25487017
22.

Cooperative substrate binding by a diguanylate cyclase.

Oliveira MC, Teixeira RD, Andrade MO, Pinheiro GM, Ramos CH, Farah CS.

J Mol Biol. 2015 Jan 30;427(2):415-32. doi: 10.1016/j.jmb.2014.11.012. Epub 2014 Nov 20.

PMID:
25463434
23.

The C-terminal region of the human p23 chaperone modulates its structure and function.

Seraphim TV, Gava LM, Mokry DZ, Cagliari TC, Barbosa LR, Ramos CH, Borges JC.

Arch Biochem Biophys. 2015 Jan 1;565:57-67. doi: 10.1016/j.abb.2014.10.015. Epub 2014 Nov 10.

PMID:
25447839
24.

αB-crystallin interacts with and prevents stress-activated proteolysis of focal adhesion kinase by calpain in cardiomyocytes.

Pereira MB, Santos AM, Gonçalves DC, Cardoso AC, Consonni SR, Gozzo FC, Oliveira PS, Pereira AH, Figueiredo AR, Tiroli-Cepeda AO, Ramos CH, de Thomaz AA, Cesar CL, Franchini KG.

Nat Commun. 2014 Oct 16;5:5159. doi: 10.1038/ncomms6159. Erratum in: Nat Commun. 2015;6:6508.

PMID:
25319025
25.
26.

Environmental and structural proteomics.

Arruda MA, Capelo JL, Lodeiro C, Ramos CH.

J Proteomics. 2014 Jun 2;104:1-3. doi: 10.1016/j.jprot.2014.04.039. No abstract available.

PMID:
24881956
27.

Conformational changes in human Hsp70 induced by high hydrostatic pressure produce oligomers with ATPase activity but without chaperone activity.

Araujo TL, Borges JC, Ramos CH, Meyer-Fernandes JR, Oliveira Júnior RS, Pascutti PG, Foguel D, Palhano FL.

Biochemistry. 2014 May 13;53(18):2884-9. doi: 10.1021/bi500004q. Epub 2014 Apr 29.

PMID:
24739062
28.

Comparative proteomics and metallomics studies in Arabidopsis thaliana leaf tissues: evaluation of the selenium addition in transgenic and nontransgenic plants using two-dimensional difference gel electrophoresis and laser ablation imaging.

Maciel BC, Barbosa HS, Pessôa GS, Salazar MM, Pereira GA, Gonçalves DC, Ramos CH, Arruda MA.

Proteomics. 2014 Apr;14(7-8):904-12. doi: 10.1002/pmic.201300427.

PMID:
24678036
29.

Structural and functional characterization of the chaperone Hsp70 from sugarcane. Insights into conformational changes during cycling from cross-linking/mass spectrometry assays.

Tiroli-Cepeda AO, Lima TB, Balbuena TS, Gozzo FC, Ramos CH.

J Proteomics. 2014 Jun 2;104:48-56. doi: 10.1016/j.jprot.2014.02.004. Epub 2014 Feb 12.

PMID:
24530624
30.

Oblique popliteal ligament - an anatomical study.

Fam LPD, Fruheling VM, Pupim B, Ramos CH, de Moura MFA, Namba M, da Silva JLV, da Cunha LAM, de Oliveira Franco APG, Filho ES.

Rev Bras Ortop. 2013 Oct 9;48(5):402-405. doi: 10.1016/j.rboe.2012.07.010. eCollection 2013 Sep-Oct.

31.

Conformational and functional studies of a cytosolic 90 kDa heat shock protein Hsp90 from sugarcane.

da Silva VC, Cagliari TC, Lima TB, Gozzo FC, Ramos CH.

Plant Physiol Biochem. 2013 Jul;68:16-22. doi: 10.1016/j.plaphy.2013.03.015. Epub 2013 Apr 6.

PMID:
23619240
32.

Chemical modifications of PhTX-I myotoxin from Porthidium hyoprora snake venom: effects on structural, enzymatic, and pharmacological properties.

Huancahuire-Vega S, Corrêa DH, Hollanda LM, Lancellotti M, Ramos CH, Ponce-Soto LA, Marangoni S.

Biomed Res Int. 2013;2013:103494. doi: 10.1155/2013/103494. Epub 2012 Dec 19.

33.

Structural and stability studies of the human mtHsp70-escort protein 1: an essential mortalin co-chaperone.

Dores-Silva PR, Minari K, Ramos CH, Barbosa LR, Borges JC.

Int J Biol Macromol. 2013 May;56:140-8. doi: 10.1016/j.ijbiomac.2013.02.009. Epub 2013 Feb 24.

34.

Biochemical characterization of uracil phosphoribosyltransferase from Mycobacterium tuberculosis.

Villela AD, Ducati RG, Rosado LA, Bloch CJ, Prates MV, Gonçalves DC, Ramos CH, Basso LA, Santos DS.

PLoS One. 2013;8(2):e56445. doi: 10.1371/journal.pone.0056445. Epub 2013 Feb 12.

35.

Identification of regions involved in substrate binding and dimer stabilization within the central domains of yeast Hsp40 Sis1.

Borges JC, Seraphim TV, Mokry DZ, Almeida FC, Cyr DM, Ramos CH.

PLoS One. 2012;7(12):e50927. doi: 10.1371/journal.pone.0050927. Epub 2012 Dec 5.

36.

Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer.

Ano Bom AP, Rangel LP, Costa DC, de Oliveira GA, Sanches D, Braga CA, Gava LM, Ramos CH, Cepeda AO, Stumbo AC, De Moura Gallo CV, Cordeiro Y, Silva JL.

J Biol Chem. 2012 Aug 10;287(33):28152-62. doi: 10.1074/jbc.M112.340638. Epub 2012 Jun 19.

37.

The stability of wild-type and deletion mutants of human C-terminus Hsp70-interacting protein (CHIP).

Millan IC, Squillace AL, Gava LM, Ramos CH.

Protein Pept Lett. 2013 May;20(5):524-9.

PMID:
22670667
38.

Proteomics: The clinical link.

Santos HM, Rodriguez-Suarez E, Lodeiro C, Arruda MA, Ramos CH, Capelo JL.

J Proteomics. 2012 Jun 6;75(10):2753-7. doi: 10.1016/j.jprot.2012.02.024. Epub 2012 Feb 23. No abstract available.

PMID:
22387114
39.

The network interaction of the human cytosolic 90 kDa heat shock protein Hsp90: A target for cancer therapeutics.

da Silva VC, Ramos CH.

J Proteomics. 2012 Jun 6;75(10):2790-802. doi: 10.1016/j.jprot.2011.12.028. Epub 2012 Jan 2. Review.

PMID:
22236519
40.

Central domain deletions affect the SAXS solution structure and function of yeast Hsp40 proteins Sis1 and Ydj1.

Silva JC, Borges JC, Cyr DM, Ramos CH, Torriani IL.

BMC Struct Biol. 2011 Oct 19;11:40. doi: 10.1186/1472-6807-11-40.

41.

Sugarcane Hsp101 is a hexameric chaperone that binds nucleotides.

Cagliari TC, da Silva VC, Borges JC, Prando A, Tasic L, Ramos CH.

Int J Biol Macromol. 2011 Dec 1;49(5):1022-30. doi: 10.1016/j.ijbiomac.2011.08.027. Epub 2011 Aug 31.

42.

Cloning, purification and characterization of a 90kDa heat shock protein from Citrus sinensis (sweet orange).

Mendonça YA, Ramos CH.

Plant Physiol Biochem. 2012 Jan;50(1):87-94. doi: 10.1016/j.plaphy.2011.08.001. Epub 2011 Aug 16.

PMID:
21873074
43.

Sir2-Related Protein 1 from Leishmania amazonensis is a glycosylated NAD+-dependent deacetylase.

Fessel MR, Lira CB, Giorgio S, Ramos CH, Cano MI.

Parasitology. 2011 Sep;138(10):1245-58. doi: 10.1017/S0031182011001077. Epub 2011 Aug 8.

PMID:
21819639
44.

Stoichiometry and thermodynamics of the interaction between the C-terminus of human 90kDa heat shock protein Hsp90 and the mitochondrial translocase of outer membrane Tom70.

Gava LM, Gonçalves DC, Borges JC, Ramos CH.

Arch Biochem Biophys. 2011 Sep 15;513(2):119-25. doi: 10.1016/j.abb.2011.06.015. Epub 2011 Jul 14.

45.

Epidemiologic profile of the leprosy of the city of Teresina, in the period of 2001-2008.

Pereira EV, Nogueira LT, Machado HA, Lima LA, Ramos CH.

An Bras Dermatol. 2011 Mar-Apr;86(2):235-40. English, Portuguese.

46.

Analysis of molecular targets of Mycobacterium tuberculosis by analytical ultracentrifugation.

Borges JC, Ramos CH.

Curr Med Chem. 2011;18(9):1276-85. Review.

PMID:
21366535
47.

Is there nascent structure in the intrinsically disordered region of troponin I?

Julien O, Mercier P, Allen CN, Fisette O, Ramos CH, Lagüe P, Blumenschein TM, Sykes BD.

Proteins. 2011 Apr;79(4):1240-50. doi: 10.1002/prot.22959. Epub 2011 Feb 14.

PMID:
21322033
48.

Human Nek6 is a monomeric mostly globular kinase with an unfolded short N-terminal domain.

Meirelles GV, Silva JC, Mendonça Yde A, Ramos CH, Torriani IL, Kobarg J.

BMC Struct Biol. 2011 Feb 14;11:12. doi: 10.1186/1472-6807-11-12.

49.

Amyloid fibril formation by circularly permuted and C-terminally deleted mutants.

Corrêa DH, Ramos CH.

Int J Biol Macromol. 2011 May 1;48(4):583-8. doi: 10.1016/j.ijbiomac.2011.01.027. Epub 2011 Feb 12.

50.

An overview of the role of molecular chaperones in protein homeostasis.

Tiroli-Cepeda AO, Ramos CH.

Protein Pept Lett. 2011 Feb;18(2):101-9. Review.

PMID:
21121892

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