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Items: 1 to 50 of 146

1.

Liquid biopsies for Hepatocellular cancer and their potential in clinical practice.

Jeffrey GP, Gordon LG, Hill MM, Ramm GA.

Hepatology. 2020 Feb 7. doi: 10.1002/hep.31168. [Epub ahead of print]

PMID:
32031686
2.

Utility of hepatic or total body iron burden in the assessment of advanced hepatic fibrosis in HFE hemochromatosis.

Chin J, Powell LW, Ramm LE, Ayonrinde OT, Ramm GA, Olynyk JK.

Sci Rep. 2019 Dec 27;9(1):20234. doi: 10.1038/s41598-019-56732-0.

3.

Regression of Fibrosis Stage With Treatment Reduces Long-Term Risk of Liver Cancer in Patients With Hemochromatosis Caused by Mutation in HFE.

Bardou-Jacquet E, Morandeau E, Anderson GJ, Ramm GA, Ramm LE, Morcet J, Bouzille G, Dixon J, Clouston AD, Lainé F, Turlin B, Powell LW, Deugnier YM.

Clin Gastroenterol Hepatol. 2019 Oct 14. pii: S1542-3565(19)31109-7. doi: 10.1016/j.cgh.2019.10.010. [Epub ahead of print]

PMID:
31622736
4.

Supersonic shear-wave elastography and APRI for the detection and staging of liver disease in pediatric cystic fibrosis.

Calvopina DA, Noble C, Weis A, Hartel GF, Ramm LE, Balouch F, Fernandez-Rojo MA, Coleman MA, Lewindon PJ, Ramm GA.

J Cyst Fibros. 2019 Jul 11. pii: S1569-1993(19)30820-3. doi: 10.1016/j.jcf.2019.06.017. [Epub ahead of print]

PMID:
31303380
5.

Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells.

Genz B, Coleman MA, Irvine KM, Kutasovic JR, Miranda M, Gratte FD, Tirnitz-Parker JEE, Olynyk JK, Calvopina DA, Weis A, Cloonan N, Robinson H, Hill MM, Al-Ejeh F, Ramm GA.

Sci Rep. 2019 Jun 12;9(1):8541. doi: 10.1038/s41598-019-44865-1.

6.

Accuracy of Transient Elastography Data Combined With APRI in Detection and Staging of Liver Disease in Pediatric Patients With Cystic Fibrosis.

Lewindon PJ, Puertolas-Lopez MV, Ramm LE, Noble C, Pereira TN, Wixey JA, Hartel GF, Calvopina DA, Leung DH, Ramm GA.

Clin Gastroenterol Hepatol. 2019 Nov;17(12):2561-2569.e5. doi: 10.1016/j.cgh.2019.03.015. Epub 2019 Mar 15.

PMID:
30880274
7.

Serum MicroRNAs as Biomarkers in Hepatitis C: Preliminary Evidence of a MicroRNA Panel for the Diagnosis of Hepatocellular Carcinoma.

Weis A, Marquart L, Calvopina DA, Genz B, Ramm GA, Skoien R.

Int J Mol Sci. 2019 Feb 17;20(4). pii: E864. doi: 10.3390/ijms20040864.

8.

Live imaging of collagen deposition during experimental hepatic schistosomiasis and recovery: a view on a dynamic process.

Harvie MCG, McManus DP, You H, Rivera VA, Nawaratna SK, MacDonald KPA, Ramm GA, Gobert GN.

Lab Invest. 2019 Feb;99(2):231-243. doi: 10.1038/s41374-018-0154-0. Epub 2018 Nov 6.

9.

Cellular Plasticity in Liver Regeneration: Spotlight on Cholangiocytes.

Tirnitz-Parker JEE, Forbes SJ, Olynyk JK, Ramm GA.

Hepatology. 2019 May;69(5):2286-2289. doi: 10.1002/hep.30340. Epub 2019 Feb 19. No abstract available.

PMID:
30382597
10.

Detection of HFE Haemochromatosis in the clinic and community using standard erythrocyte tests.

Adris N, Hazeldine S, Bentley P, Trinder D, Chua ACG, Powell LW, Ramm LE, Ramm GA, Olynyk JK.

Blood Cells Mol Dis. 2019 Feb;74:18-24. doi: 10.1016/j.bcmd.2018.10.003. Epub 2018 Oct 10.

PMID:
30340937
11.

Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes.

Barton JC, McLaren CE, Chen WP, Ramm GA, Anderson GJ, Powell LW, Subramaniam VN, Adams PC, Phatak PD, Gurrin LC, Phillips JD, Parker CJ, Emond MJ, McLaren GD.

Ann Hepatol. 2018 Aug 24;17(5):871-879. doi: 10.5604/01.3001.0012.3169.

12.

Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation.

Ikonomopoulou MP, Fernandez-Rojo MA, Pineda SS, Cabezas-Sainz P, Winnen B, Morales RAV, Brust A, Sánchez L, Alewood PF, Ramm GA, Miles JJ, King GF.

Sci Rep. 2018 Aug 1;8(1):11519. doi: 10.1038/s41598-018-29826-4.

13.

MicroRNA Sequencing Identifies a Serum MicroRNA Panel, Which Combined With Aspartate Aminotransferase to Platelet Ratio Index Can Detect and Monitor Liver Disease in Pediatric Cystic Fibrosis.

Calvopina DA, Chatfield MD, Weis A, Coleman MA, Fernandez-Rojo MA, Noble C, Ramm LE, Leung DH, Lewindon PJ, Ramm GA.

Hepatology. 2018 Dec;68(6):2301-2316. doi: 10.1002/hep.30156. Epub 2018 Nov 15.

PMID:
30014495
14.

Phenotypic analysis of hemochromatosis subtypes reveals variations in severity of iron overload and clinical disease.

Sandhu K, Flintoff K, Chatfield MD, Dixon JL, Ramm LE, Ramm GA, Powell LW, Subramaniam VN, Wallace DF.

Blood. 2018 Jul 5;132(1):101-110. doi: 10.1182/blood-2018-02-830562. Epub 2018 May 9. Review.

PMID:
29743178
15.

Self-assembling asymmetric peptide-dendrimer micelles - a platform for effective and versatile in vitro nucleic acid delivery.

Kokil GR, Veedu RN, Le BT, Ramm GA, Parekh HS.

Sci Rep. 2018 Mar 19;8(1):4832. doi: 10.1038/s41598-018-22902-9.

16.

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells.

Fernandez-Rojo MA, Deplazes E, Pineda SS, Brust A, Marth T, Wilhelm P, Martel N, Ramm GA, Mancera RL, Alewood PF, Woods GM, Belov K, Miles JJ, King GF, Ikonomopoulou MP.

Cell Death Discov. 2018 Feb 14;4:19. doi: 10.1038/s41420-018-0030-0. eCollection 2018 Dec.

17.

Schistosome-Induced Fibrotic Disease: The Role of Hepatic Stellate Cells.

Carson JP, Ramm GA, Robinson MW, McManus DP, Gobert GN.

Trends Parasitol. 2018 Jun;34(6):524-540. doi: 10.1016/j.pt.2018.02.005. Epub 2018 Mar 8. Review.

PMID:
29526403
18.

Vitamin A status in human fetuses with congenital diaphragmatic hernia: (Author reply to comment by Rocke AW and Clugston RD).

Loo CKC, Ramm GA.

Early Hum Dev. 2018 Jan;116:94. doi: 10.1016/j.earlhumdev.2017.11.004. Epub 2017 Nov 24. No abstract available.

PMID:
29239745
19.

Reduction of body iron in HFE-related haemochromatosis and moderate iron overload (Mi-Iron): a multicentre, participant-blinded, randomised controlled trial.

Ong SY, Gurrin LC, Dolling L, Dixon J, Nicoll AJ, Wolthuizen M, Wood EM, Anderson GJ, Ramm GA, Allen KJ, Olynyk JK, Crawford D, Ramm LE, Gow P, Durrant S, Powell LW, Delatycki MB.

Lancet Haematol. 2017 Dec;4(12):e607-e614. doi: 10.1016/S2352-3026(17)30214-4.

PMID:
29195602
20.

The Murine Choline-Deficient, Ethionine-Supplemented (CDE) Diet Model of Chronic Liver Injury.

Gogoi-Tiwari J, Köhn-Gaone J, Giles C, Schmidt-Arras D, Gratte FD, Elsegood CL, McCaughan GW, Ramm GA, Olynyk JK, Tirnitz-Parker JEE.

J Vis Exp. 2017 Oct 21;(128). doi: 10.3791/56138.

21.

Extracellular Vesicles in the Adaptive Process of Prostate Cancer during Inhibition of Androgen Receptor Signaling by Enzalutamide.

Soekmadji C, Rockstroh A, Ramm GA, Nelson CC, Russell PJ.

Proteomics. 2017 Dec;17(23-24). doi: 10.1002/pmic.201600427.

PMID:
29105980
22.

Lung and liver growth and retinoic acid status in human fetuses with congenital diaphragmatic hernia.

Loo CKC, Pearen MA, Pereira TN, Perry-Keene J, Payton D, Ramm GA.

Early Hum Dev. 2018 Jan;116:17-23. doi: 10.1016/j.earlhumdev.2017.10.005. Epub 2017 Nov 5.

PMID:
29096166
23.

Taurocholate Induces Biliary Differentiation of Liver Progenitor Cells Causing Hepatic Stellate Cell Chemotaxis in the Ductular Reaction: Role in Pediatric Cystic Fibrosis Liver Disease.

Pozniak KN, Pearen MA, Pereira TN, Kramer CSM, Kalita-De Croft P, Nawaratna SK, Fernandez-Rojo MA, Gobert GN, Tirnitz-Parker JEE, Olynyk JK, Shepherd RW, Lewindon PJ, Ramm GA.

Am J Pathol. 2017 Dec;187(12):2744-2757. doi: 10.1016/j.ajpath.2017.08.024. Epub 2017 Sep 19.

PMID:
28935574
24.

Extracellular vesicles for personalized therapy decision support in advanced metastatic cancers and its potential impact for prostate cancer.

Soekmadji C, Corcoran NM, Oleinikova I, Jovanovic L; Australian Prostate Cancer Collaboration BioResource, Ramm GA, Nelson CC, Jenster G, Russell PJ.

Prostate. 2017 Oct;77(14):1416-1423. doi: 10.1002/pros.23403. Epub 2017 Aug 29. Review.

PMID:
28856701
25.

Filling the Gap on Caveolin-1 in Liver Carcinogenesis.

Fernandez-Rojo MA, Ramm GA.

Trends Cancer. 2016 Dec;2(12):701-705. doi: 10.1016/j.trecan.2016.10.011. Epub 2016 Nov 8.

PMID:
28741517
26.

Serum ferritin concentration predicts hepatic fibrosis better than hepatic iron concentration in human HFE-Haemochromatosis.

Wood MJ, Crawford DHG, Wockner LF, Powell LW, Ramm GA.

Liver Int. 2017 Sep;37(9):1382-1388. doi: 10.1111/liv.13395. Epub 2017 Mar 17.

PMID:
28231420
27.

Reply.

McLaren GD, Barton JC, Ramm GA, Emond MJ, Subramaniam VN, Phatak PD, Adams PC, Powell LW, Gurrin LC, Anderson GJ, McLaren CE.

Hepatology. 2017 Mar;65(3):1072-1073. doi: 10.1002/hep.29002. Epub 2017 Feb 3. No abstract available. Erratum in: Hepatology. 2017 Jun;65(6):2136.

28.

GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes.

Barton JC, Chen WP, Emond MJ, Phatak PD, Subramaniam VN, Adams PC, Gurrin LC, Anderson GJ, Ramm GA, Powell LW, Allen KJ, Phillips JD, Parker CJ, McLaren GD, McLaren CE.

Blood Cells Mol Dis. 2017 Mar;63:15-20. doi: 10.1016/j.bcmd.2016.11.009. Epub 2016 Nov 12.

29.

Diagnosing schistosomiasis-induced liver morbidity: implications for global control.

Olveda DU, Inobaya M, Olveda RM, Vinluan ML, Ng SK, Weerakoon K, McManus DP, Ramm GA, Harn DA, Li Y, Lam AK, Guevarra JR, Ross AG.

Int J Infect Dis. 2017 Jan;54:138-144. doi: 10.1016/j.ijid.2016.10.024. Epub 2016 Nov 2.

30.

Function and Regulation of MicroRNAs and Their Potential as Biomarkers in Paediatric Liver Disease.

Calvopina DA, Coleman MA, Lewindon PJ, Ramm GA.

Int J Mol Sci. 2016 Oct 27;17(11). pii: E1795. Review.

31.

Caveolin-1 Function in Liver Physiology and Disease.

Fernandez-Rojo MA, Ramm GA.

Trends Mol Med. 2016 Oct;22(10):889-904. doi: 10.1016/j.molmed.2016.08.007. Epub 2016 Sep 12. Review.

PMID:
27633517
32.

Transient liver elastography in unsedated control children: Impact of age and intercurrent illness.

Lewindon PJ, Balouch F, Pereira TN, Puertolas-Lopez MV, Noble C, Wixey JA, Ramm GA.

J Paediatr Child Health. 2016 Jun;52(6):637-42. doi: 10.1111/jpc.13151. Epub 2016 May 20.

PMID:
27203205
33.

Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury.

Köhn-Gaone J, Dwyer BJ, Grzelak CA, Miller G, Shackel NA, Ramm GA, McCaughan GW, Elsegood CL, Olynyk JK, Tirnitz-Parker JEE.

Am J Pathol. 2016 Jul;186(7):1762-1774. doi: 10.1016/j.ajpath.2016.03.005. Epub 2016 May 13.

34.

Mechanism of pancreatic and liver malformations in human fetuses with short-rib polydactyly syndrome.

Loo CK, Pereira TN, Ramsing M, Vogel I, Petersen OB, Ramm GA.

Birth Defects Res A Clin Mol Teratol. 2016 Jul;106(7):549-62. doi: 10.1002/bdra.23495. Epub 2016 Mar 11.

PMID:
26970085
35.

Value of the 8-oxodG/dG ratio in chronic liver inflammation of patients with hepatocellular carcinoma.

Li P, Ramm GA, Macdonald GA.

Redox Biol. 2016 Aug;8:259-70. doi: 10.1016/j.redox.2016.02.003. Epub 2016 Feb 9.

36.

Reply.

McLaren CE, Barton JC, Subramaniam VN, Ramm GA, Phatak PD, Emond MJ, Gurrin LC, Adams PC, Powell LW, Anderson GJ, McLaren GD.

Hepatology. 2016 Jun;63(6):2058-60. doi: 10.1002/hep.28479. Epub 2016 Mar 15. No abstract available.

37.

Characterising granuloma regression and liver recovery in a murine model of schistosomiasis japonica.

Chuah C, Jones MK, McManus DP, Nawaratna SK, Burke ML, Owen HC, Ramm GA, Gobert GN.

Int J Parasitol. 2016 Apr;46(4):239-52. doi: 10.1016/j.ijpara.2015.12.004. Epub 2016 Jan 23.

PMID:
26812024
38.

The role of liver progenitor cells during liver regeneration, fibrogenesis, and carcinogenesis.

Köhn-Gaone J, Gogoi-Tiwari J, Ramm GA, Olynyk JK, Tirnitz-Parker JE.

Am J Physiol Gastrointest Liver Physiol. 2016 Feb 1;310(3):G143-54. doi: 10.1152/ajpgi.00215.2015. Epub 2015 Nov 25. Review.

39.

Reply.

McLaren CE, Barton JC, Phatak PD, Emond MJ, Subramaniam VN, Gurrin LC, Adams PC, Powell LW, Ramm GA, Anderson GJ, McLaren GD.

Hepatology. 2016 Jun;63(6):2056-7. doi: 10.1002/hep.28260. Epub 2015 Dec 18. No abstract available.

40.

Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron).

Ong SY, Dolling L, Dixon JL, Nicoll AJ, Gurrin LC, Wolthuizen M, Wood EM, Anderson GJ, Ramm GA, Allen KJ, Olynyk JK, Crawford D, Kava J, Ramm LE, Gow P, Durrant S, Powell LW, Delatycki MB.

BMJ Open. 2015 Aug 12;5(8):e008938. doi: 10.1136/bmjopen-2015-008938.

41.

The development of hepatic stellate cells in normal and abnormal human fetuses - an immunohistochemical study.

Loo CK, Pereira TN, Pozniak KN, Ramsing M, Vogel I, Ramm GA.

Physiol Rep. 2015 Aug;3(8). pii: e12504. doi: 10.14814/phy2.12504.

42.

Aspartate aminotransferase to platelet ratio and fibrosis-4 as biomarkers in biopsy-validated pediatric cystic fibrosis liver disease.

Leung DH, Khan M, Minard CG, Guffey D, Ramm LE, Clouston AD, Miller G, Lewindon PJ, Shepherd RW, Ramm GA.

Hepatology. 2015 Nov;62(5):1576-83. doi: 10.1002/hep.28016. Epub 2015 Sep 28. Erratum in: Hepatology. 2017 Jan;65(1):397.

PMID:
26223427
43.

Transcriptional profiling of chronic clinical hepatic schistosomiasis japonica indicates reduced metabolism and immune responses.

Gobert GN, Burke ML, McManus DP, Ellis MK, Chuah C, Ramm GA, Wang Y, Li Y.

Parasitology. 2015 Oct;142(12):1453-68. doi: 10.1017/S0031182015000682. Epub 2015 Jul 28.

PMID:
26216487
44.

Case Report: Fetal Bilateral Diaphragmatic Agenesis, Ectopic Liver and Abnormal Pancreas.

Loo CK, Pereira TN, Ramm GA.

Fetal Pediatr Pathol. 2015;34(4):216-22. doi: 10.3109/15513815.2015.1042605. Epub 2015 Jun 1.

PMID:
26030091
45.

An ex vivo model for studying hepatic schistosomiasis and the effect of released protein from dying eggs.

Gobert GN, Nawaratna SK, Harvie M, Ramm GA, McManus DP.

PLoS Negl Trop Dis. 2015 May 12;9(5):e0003760. doi: 10.1371/journal.pntd.0003760. eCollection 2015 May.

46.

Type 2 diabetes mellitus: limitations of conventional therapies and intervention with nucleic acid-based therapeutics.

Kokil GR, Veedu RN, Ramm GA, Prins JB, Parekh HS.

Chem Rev. 2015 Jun 10;115(11):4719-43. doi: 10.1021/cr5002832. Epub 2015 Apr 28. Review. No abstract available.

PMID:
25918949
47.

Reply: To PMID 25605615.

McLaren CE, Emond MJ, Subramaniam VN, Phatak PD, Barton JC, Adams PC, Powell LW, Gurrin LC, Ramm GA, Anderson GJ, McLaren GD.

Hepatology. 2015 Dec;62(6):1918-9. doi: 10.1002/hep.27851. Epub 2015 Jun 3. No abstract available.

PMID:
25914125
48.

Reduced mortality due to phlebotomy in moderately iron-loaded HFE haemochromatosis? The need for clinical trials.

Delatycki MB, Gurrin LC, Ong SY, Ramm GA, Anderson GJ, Olynyk JK, Allen KJ, Nicoll AJ, Powell LW.

J Hepatol. 2015 Jul;63(1):282-3. doi: 10.1016/j.jhep.2015.03.028. Epub 2015 Apr 1. No abstract available.

49.

Circulating microRNAs as noninvasive diagnostic biomarkers of liver disease in children with cystic fibrosis.

Cook NL, Pereira TN, Lewindon PJ, Shepherd RW, Ramm GA.

J Pediatr Gastroenterol Nutr. 2015 Feb;60(2):247-54. doi: 10.1097/MPG.0000000000000600.

PMID:
25625579
50.

Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload.

McLaren CE, Emond MJ, Subramaniam VN, Phatak PD, Barton JC, Adams PC, Goh JB, McDonald CJ, Powell LW, Gurrin LC, Allen KJ, Nickerson DA, Louie T, Ramm GA, Anderson GJ, McLaren GD.

Hepatology. 2015 Aug;62(2):429-39. doi: 10.1002/hep.27711. Epub 2015 Mar 18.

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