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Items: 1 to 50 of 221

1.

Supersonic shear-wave elastography and APRI for the detection and staging of liver disease in pediatric cystic fibrosis.

Calvopina DA, Noble C, Weis A, Hartel GF, Ramm LE, Balouch F, Fernandez-Rojo MA, Coleman MA, Lewindon PJ, Ramm GA.

J Cyst Fibros. 2019 Jul 11. pii: S1569-1993(19)30820-3. doi: 10.1016/j.jcf.2019.06.017. [Epub ahead of print]

PMID:
31303380
2.

Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells.

Genz B, Coleman MA, Irvine KM, Kutasovic JR, Miranda M, Gratte FD, Tirnitz-Parker JEE, Olynyk JK, Calvopina DA, Weis A, Cloonan N, Robinson H, Hill MM, Al-Ejeh F, Ramm GA.

Sci Rep. 2019 Jun 12;9(1):8541. doi: 10.1038/s41598-019-44865-1.

3.

Limiting Neuronal Nogo Receptor 1 Signaling during Experimental Autoimmune Encephalomyelitis Preserves Axonal Transport and Abrogates Inflammatory Demyelination.

Lee JY, Kim MJ, Thomas S, Oorschot V, Ramm G, Aui PM, Sekine Y, Deliyanti D, Wilkinson-Berka J, Niego B, Harvey AR, Theotokis P, McLean C, Strittmatter SM, Petratos S.

J Neurosci. 2019 Jul 10;39(28):5562-5580. doi: 10.1523/JNEUROSCI.1760-18.2019. Epub 2019 May 6.

PMID:
31061088
4.

Accuracy of Transient Elastography Data Combined With APRI in Detection and Staging of Liver Disease in Pediatric Patients With Cystic Fibrosis.

Lewindon PJ, Puertolas-Lopez MV, Ramm LE, Noble C, Pereira TN, Wixey JA, Hartel GF, Calvopina DA, Leung DH, Ramm GA.

Clin Gastroenterol Hepatol. 2019 Mar 15. pii: S1542-3565(19)30279-4. doi: 10.1016/j.cgh.2019.03.015. [Epub ahead of print]

PMID:
30880274
5.

Serum MicroRNAs as Biomarkers in Hepatitis C: Preliminary Evidence of a MicroRNA Panel for the Diagnosis of Hepatocellular Carcinoma.

Weis A, Marquart L, Calvopina DA, Genz B, Ramm GA, Skoien R.

Int J Mol Sci. 2019 Feb 17;20(4). pii: E864. doi: 10.3390/ijms20040864.

6.

Live imaging of collagen deposition during experimental hepatic schistosomiasis and recovery: a view on a dynamic process.

Harvie MCG, McManus DP, You H, Rivera VA, Nawaratna SK, MacDonald KPA, Ramm GA, Gobert GN.

Lab Invest. 2019 Feb;99(2):231-243. doi: 10.1038/s41374-018-0154-0. Epub 2018 Nov 6.

PMID:
30401957
7.

Cellular Plasticity in Liver Regeneration: Spotlight on Cholangiocytes.

Tirnitz-Parker JEE, Forbes SJ, Olynyk JK, Ramm GA.

Hepatology. 2019 May;69(5):2286-2289. doi: 10.1002/hep.30340. Epub 2019 Feb 19. No abstract available.

PMID:
30382597
8.

Detection of HFE Haemochromatosis in the clinic and community using standard erythrocyte tests.

Adris N, Hazeldine S, Bentley P, Trinder D, Chua ACG, Powell LW, Ramm LE, Ramm GA, Olynyk JK.

Blood Cells Mol Dis. 2019 Feb;74:18-24. doi: 10.1016/j.bcmd.2018.10.003. Epub 2018 Oct 10.

PMID:
30340937
9.

Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes.

Barton JC, McLaren CE, Chen WP, Ramm GA, Anderson GJ, Powell LW, Subramaniam VN, Adams PC, Phatak PD, Gurrin LC, Phillips JD, Parker CJ, Emond MJ, McLaren GD.

Ann Hepatol. 2018 Aug 24;17(5):871-879. doi: 10.5604/01.3001.0012.3169.

10.

The first transmembrane region of complement component-9 acts as a brake on its self-assembly.

Spicer BA, Law RHP, Caradoc-Davies TT, Ekkel SM, Bayly-Jones C, Pang SS, Conroy PJ, Ramm G, Radjainia M, Venugopal H, Whisstock JC, Dunstone MA.

Nat Commun. 2018 Aug 15;9(1):3266. doi: 10.1038/s41467-018-05717-0.

11.

Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation.

Ikonomopoulou MP, Fernandez-Rojo MA, Pineda SS, Cabezas-Sainz P, Winnen B, Morales RAV, Brust A, Sánchez L, Alewood PF, Ramm GA, Miles JJ, King GF.

Sci Rep. 2018 Aug 1;8(1):11519. doi: 10.1038/s41598-018-29826-4.

12.

MicroRNA Sequencing Identifies a Serum MicroRNA Panel, Which Combined With Aspartate Aminotransferase to Platelet Ratio Index Can Detect and Monitor Liver Disease in Pediatric Cystic Fibrosis.

Calvopina DA, Chatfield MD, Weis A, Coleman MA, Fernandez-Rojo MA, Noble C, Ramm LE, Leung DH, Lewindon PJ, Ramm GA.

Hepatology. 2018 Dec;68(6):2301-2316. doi: 10.1002/hep.30156. Epub 2018 Nov 15.

PMID:
30014495
13.

Helicobacter pylori Outer Membrane Vesicle Size Determines Their Mechanisms of Host Cell Entry and Protein Content.

Turner L, Bitto NJ, Steer DL, Lo C, D'Costa K, Ramm G, Shambrook M, Hill AF, Ferrero RL, Kaparakis-Liaskos M.

Front Immunol. 2018 Jul 2;9:1466. doi: 10.3389/fimmu.2018.01466. eCollection 2018.

14.

Testing of therapies in a novel nebulin nemaline myopathy model demonstrate a lack of efficacy.

Sztal TE, McKaige EA, Williams C, Oorschot V, Ramm G, Bryson-Richardson RJ.

Acta Neuropathol Commun. 2018 May 30;6(1):40. doi: 10.1186/s40478-018-0546-9.

15.

Phenotypic analysis of hemochromatosis subtypes reveals variations in severity of iron overload and clinical disease.

Sandhu K, Flintoff K, Chatfield MD, Dixon JL, Ramm LE, Ramm GA, Powell LW, Subramaniam VN, Wallace DF.

Blood. 2018 Jul 5;132(1):101-110. doi: 10.1182/blood-2018-02-830562. Epub 2018 May 9. Review.

16.

Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis.

Deo P, Chow SH, Hay ID, Kleifeld O, Costin A, Elgass KD, Jiang JH, Ramm G, Gabriel K, Dougan G, Lithgow T, Heinz E, Naderer T.

PLoS Pathog. 2018 Mar 30;14(3):e1006945. doi: 10.1371/journal.ppat.1006945. eCollection 2018 Mar.

17.

Self-assembling asymmetric peptide-dendrimer micelles - a platform for effective and versatile in vitro nucleic acid delivery.

Kokil GR, Veedu RN, Le BT, Ramm GA, Parekh HS.

Sci Rep. 2018 Mar 19;8(1):4832. doi: 10.1038/s41598-018-22902-9.

18.

Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells.

Fernandez-Rojo MA, Deplazes E, Pineda SS, Brust A, Marth T, Wilhelm P, Martel N, Ramm GA, Mancera RL, Alewood PF, Woods GM, Belov K, Miles JJ, King GF, Ikonomopoulou MP.

Cell Death Discov. 2018 Feb 14;4:19. doi: 10.1038/s41420-018-0030-0. eCollection 2018 Dec.

19.

Schistosome-Induced Fibrotic Disease: The Role of Hepatic Stellate Cells.

Carson JP, Ramm GA, Robinson MW, McManus DP, Gobert GN.

Trends Parasitol. 2018 Jun;34(6):524-540. doi: 10.1016/j.pt.2018.02.005. Epub 2018 Mar 8. Review.

PMID:
29526403
20.

Methods in renal research: Measurement of autophagic flux in the renal cortex ex vivo.

Higgins GC, Nguyen TV, Ramm G, Coughlan MT.

Nephrology (Carlton). 2018 Sep;23(9):815-820. doi: 10.1111/nep.13251.

PMID:
29504645
21.

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.

McArthur K, Whitehead LW, Heddleston JM, Li L, Padman BS, Oorschot V, Geoghegan ND, Chappaz S, Davidson S, San Chin H, Lane RM, Dramicanin M, Saunders TL, Sugiana C, Lessene R, Osellame LD, Chew TL, Dewson G, Lazarou M, Ramm G, Lessene G, Ryan MT, Rogers KL, van Delft MF, Kile BT.

Science. 2018 Feb 23;359(6378). pii: eaao6047. doi: 10.1126/science.aao6047.

PMID:
29472455
22.

An ultrastructural investigation of tumors undergoing regression mediated by immunotherapy.

Westwood JA, Ellis S, Danne J, Johnson C, Oorschot V, Ramm G, Tscharke DC, Davenport AJ, Whisstock JC, Darcy PK, Kershaw MH, Slaney CY.

Oncotarget. 2017 Dec 14;8(70):115215-115229. doi: 10.18632/oncotarget.23215. eCollection 2017 Dec 29.

23.

Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes.

Barton JC, McLaren CE, Chen WP, Ramm GA, Anderson GJ, Powell LW, Subramaniam VN, Adams PC, Phatak PD, Gurrin LC, Phillips JD, Parker CJ, Emond MJ, McLaren GD.

Ann Hepatol. 2018 Sep - Oct;17(5):871-879. doi: 10.5604/01.3001.0012.3169.

24.

Vitamin A status in human fetuses with congenital diaphragmatic hernia: (Author reply to comment by Rocke AW and Clugston RD).

Loo CKC, Ramm GA.

Early Hum Dev. 2018 Jan;116:94. doi: 10.1016/j.earlhumdev.2017.11.004. Epub 2017 Nov 24. No abstract available.

PMID:
29239745
25.

Reduction of body iron in HFE-related haemochromatosis and moderate iron overload (Mi-Iron): a multicentre, participant-blinded, randomised controlled trial.

Ong SY, Gurrin LC, Dolling L, Dixon J, Nicoll AJ, Wolthuizen M, Wood EM, Anderson GJ, Ramm GA, Allen KJ, Olynyk JK, Crawford D, Ramm LE, Gow P, Durrant S, Powell LW, Delatycki MB.

Lancet Haematol. 2017 Dec;4(12):e607-e614. doi: 10.1016/S2352-3026(17)30214-4.

PMID:
29195602
26.

The Murine Choline-Deficient, Ethionine-Supplemented (CDE) Diet Model of Chronic Liver Injury.

Gogoi-Tiwari J, Köhn-Gaone J, Giles C, Schmidt-Arras D, Gratte FD, Elsegood CL, McCaughan GW, Ramm GA, Olynyk JK, Tirnitz-Parker JEE.

J Vis Exp. 2017 Oct 21;(128). doi: 10.3791/56138.

PMID:
29155718
27.

Overcoming Monocarboxylate Transporter 8 (MCT8)-Deficiency to Promote Human Oligodendrocyte Differentiation and Myelination.

Lee JY, Kim MJ, Deliyanti D, Azari MF, Rossello F, Costin A, Ramm G, Stanley EG, Elefanty AG, Wilkinson-Berka JL, Petratos S.

EBioMedicine. 2017 Nov;25:122-135. doi: 10.1016/j.ebiom.2017.10.016. Epub 2017 Oct 19.

28.

Extracellular Vesicles in the Adaptive Process of Prostate Cancer during Inhibition of Androgen Receptor Signaling by Enzalutamide.

Soekmadji C, Rockstroh A, Ramm GA, Nelson CC, Russell PJ.

Proteomics. 2017 Dec;17(23-24). doi: 10.1002/pmic.201600427.

PMID:
29105980
29.

Lung and liver growth and retinoic acid status in human fetuses with congenital diaphragmatic hernia.

Loo CKC, Pearen MA, Pereira TN, Perry-Keene J, Payton D, Ramm GA.

Early Hum Dev. 2018 Jan;116:17-23. doi: 10.1016/j.earlhumdev.2017.10.005. Epub 2017 Nov 5.

PMID:
29096166
30.

Taurocholate Induces Biliary Differentiation of Liver Progenitor Cells Causing Hepatic Stellate Cell Chemotaxis in the Ductular Reaction: Role in Pediatric Cystic Fibrosis Liver Disease.

Pozniak KN, Pearen MA, Pereira TN, Kramer CSM, Kalita-De Croft P, Nawaratna SK, Fernandez-Rojo MA, Gobert GN, Tirnitz-Parker JEE, Olynyk JK, Shepherd RW, Lewindon PJ, Ramm GA.

Am J Pathol. 2017 Dec;187(12):2744-2757. doi: 10.1016/j.ajpath.2017.08.024. Epub 2017 Sep 19.

PMID:
28935574
31.

Extracellular vesicles for personalized therapy decision support in advanced metastatic cancers and its potential impact for prostate cancer.

Soekmadji C, Corcoran NM, Oleinikova I, Jovanovic L; Australian Prostate Cancer Collaboration BioResource, Ramm GA, Nelson CC, Jenster G, Russell PJ.

Prostate. 2017 Oct;77(14):1416-1423. doi: 10.1002/pros.23403. Epub 2017 Aug 29. Review.

PMID:
28856701
32.

Filling the Gap on Caveolin-1 in Liver Carcinogenesis.

Fernandez-Rojo MA, Ramm GA.

Trends Cancer. 2016 Dec;2(12):701-705. doi: 10.1016/j.trecan.2016.10.011. Epub 2016 Nov 8.

PMID:
28741517
33.

Serum ferritin concentration predicts hepatic fibrosis better than hepatic iron concentration in human HFE-Haemochromatosis.

Wood MJ, Crawford DHG, Wockner LF, Powell LW, Ramm GA.

Liver Int. 2017 Sep;37(9):1382-1388. doi: 10.1111/liv.13395. Epub 2017 Mar 17.

PMID:
28231420
34.

Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway.

Weeden CE, Chen Y, Ma SB, Hu Y, Ramm G, Sutherland KD, Smyth GK, Asselin-Labat ML.

PLoS Biol. 2017 Jan 26;15(1):e2000731. doi: 10.1371/journal.pbio.2000731. eCollection 2017 Jan.

35.

Reply.

McLaren GD, Barton JC, Ramm GA, Emond MJ, Subramaniam VN, Phatak PD, Adams PC, Powell LW, Gurrin LC, Anderson GJ, McLaren CE.

Hepatology. 2017 Mar;65(3):1072-1073. doi: 10.1002/hep.29002. Epub 2017 Feb 3. No abstract available. Erratum in: Hepatology. 2017 Jun;65(6):2136.

36.

INPP5E regulates phosphoinositide-dependent cilia transition zone function.

Dyson JM, Conduit SE, Feeney SJ, Hakim S, DiTommaso T, Fulcher AJ, Sriratana A, Ramm G, Horan KA, Gurung R, Wicking C, Smyth I, Mitchell CA.

J Cell Biol. 2017 Jan 2;216(1):247-263. doi: 10.1083/jcb.201511055. Epub 2016 Dec 20.

37.

GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes.

Barton JC, Chen WP, Emond MJ, Phatak PD, Subramaniam VN, Adams PC, Gurrin LC, Anderson GJ, Ramm GA, Powell LW, Allen KJ, Phillips JD, Parker CJ, McLaren GD, McLaren CE.

Blood Cells Mol Dis. 2017 Mar;63:15-20. doi: 10.1016/j.bcmd.2016.11.009. Epub 2016 Nov 12.

38.

Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.

Nguyen TN, Padman BS, Usher J, Oorschot V, Ramm G, Lazarou M.

J Cell Biol. 2016 Dec 19;215(6):857-874. Epub 2016 Nov 18.

39.

Diagnosing schistosomiasis-induced liver morbidity: implications for global control.

Olveda DU, Inobaya M, Olveda RM, Vinluan ML, Ng SK, Weerakoon K, McManus DP, Ramm GA, Harn DA, Li Y, Lam AK, Guevarra JR, Ross AG.

Int J Infect Dis. 2017 Jan;54:138-144. doi: 10.1016/j.ijid.2016.10.024. Epub 2016 Nov 2.

40.

Function and Regulation of MicroRNAs and Their Potential as Biomarkers in Paediatric Liver Disease.

Calvopina DA, Coleman MA, Lewindon PJ, Ramm GA.

Int J Mol Sci. 2016 Oct 27;17(11). pii: E1795. Review.

41.

FLNC myofibrillar myopathy results from impaired autophagy and protein insufficiency.

Ruparelia AA, Oorschot V, Ramm G, Bryson-Richardson RJ.

Hum Mol Genet. 2016 Jun 1;25(11):2131-2142. Epub 2016 Mar 11.

PMID:
26969713
42.

Variants in the Oxidoreductase PYROXD1 Cause Early-Onset Myopathy with Internalized Nuclei and Myofibrillar Disorganization.

O'Grady GL, Best HA, Sztal TE, Schartner V, Sanjuan-Vazquez M, Donkervoort S, Abath Neto O, Sutton RB, Ilkovski B, Romero NB, Stojkovic T, Dastgir J, Waddell LB, Boland A, Hu Y, Williams C, Ruparelia AA, Maisonobe T, Peduto AJ, Reddel SW, Lek M, Tukiainen T, Cummings BB, Joshi H, Nectoux J, Brammah S, Deleuze JF, Ing VO, Ramm G, Ardicli D, Nowak KJ, Talim B, Topaloglu H, Laing NG, North KN, MacArthur DG, Friant S, Clarke NF, Bryson-Richardson RJ, Bönnemann CG, Laporte J, Cooper ST.

Am J Hum Genet. 2016 Nov 3;99(5):1086-1105. doi: 10.1016/j.ajhg.2016.09.005. Epub 2016 Oct 13.

43.

Visualising coordination chemistry: fluorescence X-ray absorption near edge structure tomography.

James SA, Burke R, Howard DL, Spiers KM, Paterson DJ, Murphy S, Ramm G, Kirkham R, Ryan CG, de Jonge MD.

Chem Commun (Camb). 2016 Sep 27;52(79):11834-11837.

PMID:
27722440
44.

Caveolin-1 Function in Liver Physiology and Disease.

Fernandez-Rojo MA, Ramm GA.

Trends Mol Med. 2016 Oct;22(10):889-904. doi: 10.1016/j.molmed.2016.08.007. Epub 2016 Sep 12. Review.

PMID:
27633517
45.

Transient liver elastography in unsedated control children: Impact of age and intercurrent illness.

Lewindon PJ, Balouch F, Pereira TN, Puertolas-Lopez MV, Noble C, Wixey JA, Ramm GA.

J Paediatr Child Health. 2016 Jun;52(6):637-42. doi: 10.1111/jpc.13151. Epub 2016 May 20.

PMID:
27203205
46.

Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury.

Köhn-Gaone J, Dwyer BJ, Grzelak CA, Miller G, Shackel NA, Ramm GA, McCaughan GW, Elsegood CL, Olynyk JK, Tirnitz-Parker JEE.

Am J Pathol. 2016 Jul;186(7):1762-1774. doi: 10.1016/j.ajpath.2016.03.005. Epub 2016 May 13.

PMID:
27181403
47.

Mechanism of pancreatic and liver malformations in human fetuses with short-rib polydactyly syndrome.

Loo CK, Pereira TN, Ramsing M, Vogel I, Petersen OB, Ramm GA.

Birth Defects Res A Clin Mol Teratol. 2016 Jul;106(7):549-62. doi: 10.1002/bdra.23495. Epub 2016 Mar 11.

PMID:
26970085
48.

Value of the 8-oxodG/dG ratio in chronic liver inflammation of patients with hepatocellular carcinoma.

Li P, Ramm GA, Macdonald GA.

Redox Biol. 2016 Aug;8:259-70. doi: 10.1016/j.redox.2016.02.003. Epub 2016 Feb 9.

49.

Reply.

McLaren CE, Barton JC, Subramaniam VN, Ramm GA, Phatak PD, Emond MJ, Gurrin LC, Adams PC, Powell LW, Anderson GJ, McLaren GD.

Hepatology. 2016 Jun;63(6):2058-60. doi: 10.1002/hep.28479. Epub 2016 Mar 15. No abstract available.

50.

Structure of the poly-C9 component of the complement membrane attack complex.

Dudkina NV, Spicer BA, Reboul CF, Conroy PJ, Lukoyanova N, Elmlund H, Law RH, Ekkel SM, Kondos SC, Goode RJ, Ramm G, Whisstock JC, Saibil HR, Dunstone MA.

Nat Commun. 2016 Feb 4;7:10588. doi: 10.1038/ncomms10588.

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