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Items: 1 to 50 of 70

1.

Novel Inhaled Pan-JAK Inhibitor, LAS194046, Reduces Allergen-Induced Airway Inflammation, Late Asthmatic Response, and pSTAT Activation in Brown Norway Rats.

Calbet M, Ramis I, Calama E, Carreño C, Paris S, Maldonado M, Orellana A, Calaf E, Pauta M, De Alba J, Bach J, Miralpeix M.

J Pharmacol Exp Ther. 2019 Aug;370(2):137-147. doi: 10.1124/jpet.119.256263. Epub 2019 May 13.

PMID:
31085698
2.

Mycobacterium avium: an overview.

Busatto C, Vianna JS, da Silva LV Junior, Ramis IB, da Silva PEA.

Tuberculosis (Edinb). 2019 Jan;114:127-134. doi: 10.1016/j.tube.2018.12.004. Epub 2019 Jan 4. Review.

PMID:
30711152
3.

Tetrahydropyridine derivative as efflux inhibitor in Mycobacterium abscessus.

Vianna JS, Ramis IB, Bierhals D, von Groll A, Ramos DF, Zanatta N, Lourenço MC, Viveiros M, Almeida da Silva PE.

J Glob Antimicrob Resist. 2019 Jun;17:296-299. doi: 10.1016/j.jgar.2018.12.020. Epub 2019 Jan 7.

PMID:
30630106
4.

Antimicrobial Resistance and Molecular Characterization of Extended-Spectrum β-Lactamases of Escherichia coli and Klebsiella spp. Isolates from Urinary Tract Infections in Southern Brazil.

Pereira JL, Volcão LM, Klafke GB, Vieira RS, Gonçalves CV, Ramis IB, da Silva PEA, von Groll A.

Microb Drug Resist. 2019 Mar;25(2):173-181. doi: 10.1089/mdr.2018.0046. Epub 2018 Aug 22.

PMID:
30133334
5.

The interplay between mutations in cagA, 23S rRNA, gyrA and drug resistance in Helicobacter pylori.

Vianna JS, Ramis IB, Ramos DF, Gastal OL, Silva RAD, Gonçalves CV, Silva PEAD.

Rev Inst Med Trop Sao Paulo. 2018;60:e25. doi: 10.1590/s1678-9946201860025. Epub 2018 Jun 28.

6.

Antifungal activity of diphenyl diselenide alone and in combination with itraconazole against Sporothrix brasiliensis.

Poester VR, Mattei AS, Mendes JF, Klafke GB, Ramis IB, Sanchotene KO, Xavier MO.

Med Mycol. 2019 Apr 1;57(3):328-331. doi: 10.1093/mmy/myy044.

PMID:
29924365
7.

Antimicrobial and Efflux Inhibitor Activity of Usnic Acid Against Mycobacterium abscessus.

Ramis IB, Vianna JS, Reis AJ, von Groll A, Ramos DF, Viveiros M, da Silva PEA.

Planta Med. 2018 Nov;84(17):1265-1270. doi: 10.1055/a-0639-5412. Epub 2018 Jun 18.

PMID:
29913527
8.

PI3K, p38 and JAK/STAT signalling in bronchial tissue from patients with asthma following allergen challenge.

Southworth T, Mason S, Bell A, Ramis I, Calbet M, Domenech A, Prats N, Miralpeix M, Singh D.

Biomark Res. 2018 Apr 11;6:14. doi: 10.1186/s40364-018-0128-9. eCollection 2018.

9.

High frequency of aac(6')-Ib-cr gene associated with double mutations in gyrA and parC in Escherichia coli isolates from patients with urinary tract infections.

Volcão LM, Lacava JP, Gewehr MF, Leal VL, Ramis IB, Ramos DF, Gonçalves CV, Possuelo LG, Minarini LAR, da Silva PEA, von Groll A.

J Glob Antimicrob Resist. 2018 Jun;13:180-183. doi: 10.1016/j.jgar.2017.12.013. Epub 2018 Jan 4.

PMID:
29307860
10.

Activity of Rifabutin and Hemi-synthetic Derivatives Against Mycobacterium abscessus.

Ramis IB, Figueiredo R, Ramos DF, Halicki PCB, von Groll A, Viveiros M, do Ceu Costa M, da Silva PEA.

Med Chem. 2018;14(4):394-399. doi: 10.2174/1573406414666171204102633.

PMID:
29205119
11.

Tofacitinib ameliorates inflammation in a rat model of airway neutrophilia induced by inhaled LPS.

Calama E, Ramis I, Domènech A, Carreño C, De Alba J, Prats N, Miralpeix M.

Pulm Pharmacol Ther. 2017 Apr;43:60-67. doi: 10.1016/j.pupt.2017.01.002. Epub 2017 Jan 10.

PMID:
28087469
12.

Anti-inflammatory potential of PI3Kδ and JAK inhibitors in asthma patients.

Southworth T, Plumb J, Gupta V, Pearson J, Ramis I, Lehner MD, Miralpeix M, Singh D.

Respir Res. 2016 Oct 4;17(1):124.

13.

DRUG RESISTANCE IN HELICOBACTER PYLORI.

Vianna JS, Ramis IB, Ramos DF, VON Groll A, Silva PE.

Arq Gastroenterol. 2016 Oct-Dec;53(4):215-223. doi: 10.1590/S0004-28032016000400002. Review.

14.

Relationship of interleukin-1B gene promoter region polymorphism with Helicobacter pylori infection and gastritis.

Ramis IB, Vianna JS, Halicki PC, Lara C, Tadiotto TF, da Silva Maciel JB, Gonçalves CV, von Groll A, Dellagostin OA, da Silva PE.

J Infect Dev Ctries. 2015 Sep 29;9(10):1108-16. doi: 10.3855/jidc.6123.

15.

Detection of Helicobacter pylori CagA EPIYA in gastric biopsy specimens and its relation to gastric diseases.

Vianna JS, Ramis IB, Halicki PC, Gastal OL, Silva RA, Junior JS, Dos Santos DM, Chaves AL, Juliano CR, Jannke HA, da Silva LV Jr, Von Groll A, da Silva PE.

Diagn Microbiol Infect Dis. 2015 Oct;83(2):89-92. doi: 10.1016/j.diagmicrobio.2015.05.017. Epub 2015 Jun 10.

PMID:
26144892
16.

A novel inhaled Syk inhibitor blocks mast cell degranulation and early asthmatic response.

Ramis I, Otal R, Carreño C, Domènech A, Eichhorn P, Orellana A, Maldonado M, De Alba J, Prats N, Fernández JC, Vidal B, Miralpeix M.

Pharmacol Res. 2015 Sep;99:116-24. doi: 10.1016/j.phrs.2015.05.011. Epub 2015 Jun 4.

PMID:
26051661
17.

Polymorphisms of the IL-6, IL-8 and IL-10 genes and the risk of gastric pathology in patients infected with Helicobacter pylori.

Ramis IB, Vianna JS, Gonçalves CV, von Groll A, Dellagostin OA, da Silva PEA.

J Microbiol Immunol Infect. 2017 Apr;50(2):153-159. doi: 10.1016/j.jmii.2015.03.002. Epub 2015 Mar 24.

18.

Antimicrobial susceptibility of rapidly growing mycobacteria using the rapid colorimetric method.

Ramis IB, Cnockaert M, von Groll A, Nogueira CL, Leão SC, Andre E, Simon A, Palomino JC, da Silva PE, Vandamme P, Martin A.

Eur J Clin Microbiol Infect Dis. 2015 Jul;34(7):1403-13. doi: 10.1007/s10096-015-2365-2. Epub 2015 Mar 29.

PMID:
25820290
19.

Evaluation of the Speed-Oligo Mycobacteria assay for the identification of nontuberculous mycobacteria.

Ramis IB, Cnockaert M, Von Groll A, Mathys V, Simon A, Tortoli E, Palomino JC, Almeida da Silva PE, Vandamme P, Andre E, Martin A.

J Med Microbiol. 2015 Mar;64(Pt 3):283-7. doi: 10.1099/jmm.0.000025. Epub 2015 Jan 16.

PMID:
25596120
20.

Authors reply: cagE as a biomarker of the pathogenicity of Helicobacter pylori.

Ramis IB, Vianna JS, Silva Junior LV, Von Groll A, da Silva PE.

Rev Soc Bras Med Trop. 2014 May-Jun;47(3):404. No abstract available.

21.

cagE as a biomarker of the pathogenicity of Helicobacter pylori.

Ramis IB, Vianna JS, Silva Junior LV, Von Groll A, Silva PE.

Rev Soc Bras Med Trop. 2013 Mar-Apr;46(2):185-9. doi: 10.1590/0037-8682-0054-2012.

22.

Highly potent aminopyridines as Syk kinase inhibitors.

Castillo M, Forns P, Erra M, Mir M, López M, Maldonado M, Orellana A, Carreño C, Ramis I, Miralpeix M, Vidal B.

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5419-23. doi: 10.1016/j.bmcl.2012.07.045. Epub 2012 Jul 20.

PMID:
22877633
23.

Improving tuberculosis control through the partnership between university and the health system.

Valença MS, da Rocha JZ, Ramis IB, Carrion LL, Madruga C, de Macedo MB, Scaini CJ, von Groll A, da Silva PE.

Rev Soc Bras Med Trop. 2012 Jul-Aug;45(4):491-5. Epub 2012 Jul 5.

24.

Evaluation of diagnostic methods for the detection of Helicobacter pylori in gastric biopsy specimens of dyspeptic patients.

Ramis IB, de Moraes EP, Fernandes MS, Mendoza-Sassi R, Rodrigues O, Juliano CR, Scaini CJ, da Silva PE.

Braz J Microbiol. 2012 Jul;43(3):903-8. doi: 10.1590/S1517-83822012000300008. Epub 2012 Jun 1.

25.

Pyrazine-based Syk kinase inhibitors.

Forns P, Esteve C, Taboada L, Alonso JA, Orellana A, Maldonado M, Carreño C, Ramis I, López M, Miralpeix M, Vidal B.

Bioorg Med Chem Lett. 2012 Apr 15;22(8):2784-8. doi: 10.1016/j.bmcl.2012.02.087. Epub 2012 Mar 2.

PMID:
22425453
26.

Characterization of a model of tracheal plasma extravasation in passively sensitized rats using anti-allergic and anti-inflammatory drugs by oral and intratracheal route.

Carreño C, Domènech A, Prats N, Miralpeix M, Ramis I.

Pulm Pharmacol Ther. 2012 Feb;25(1):87-93. doi: 10.1016/j.pupt.2011.12.002. Epub 2011 Dec 22.

PMID:
22207135
27.

Molecular Basis of pathogenicity in Helicobacter pylori clinical isolates.

Ramis IB, Fonseca TL, de Moraes EP, Fernandes MS, Mendoza-Sassi R, Rodrigues O, Juliano CR, Scaini CJ, da Silva PE.

J Clin Microbiol. 2010 Oct;48(10):3776-8. doi: 10.1128/JCM.00472-10. Epub 2010 Aug 4.

28.

The new salicylate derivative UR-1505 modulates the Th2/humoral response in a dextran sodium sulphate model of colitis that resembles ulcerative colitis.

Bailón E, Román J, Ramis I, Michelena P, Balsa D, Merlos M, Zarzuelo A, Gálvez J, Comalada M.

J Pharmacol Sci. 2009 Feb;109(2):315-8.

29.

UR-1505, a salicylate able to selectively block T-cell activation, shows intestinal anti-inflammatory activity in the chronic phase of the DSS model of rat colitis.

Bailón E, Comalada M, Román J, Michelena P, Ramis I, Merlos M, Nieto A, Concha A, Zarzuelo A, Gálvez J.

Inflamm Bowel Dis. 2008 Jul;14(7):888-97. doi: 10.1002/ibd.20381.

PMID:
18253952
30.

The intestinal anti-inflammatory effects of the novel agent UR-1505 in the TNBS model of rat colitis are mediated by T-lymphocyte inhibition.

Bailón E, Camuesco D, Nieto A, Concha A, Fernández de Arriba A, Román J, Ramis I, Merlos M, Zarzuelo A, Gálvez J, Comalada M.

Biochem Pharmacol. 2007 Nov 15;74(10):1496-506. Epub 2007 Jul 22.

PMID:
17720145
31.

UR-1505, a new salicylate, blocks T cell activation through nuclear factor of activated T cells.

Román J, de Arriba AF, Barrón S, Michelena P, Giral M, Merlos M, Bailón E, Comalada M, Gálvez J, Zarzuelo A, Ramis I.

Mol Pharmacol. 2007 Aug;72(2):269-79. Epub 2007 May 2.

PMID:
17475810
32.

Inflammatory markers in bronchoalveolar lavage fluid from human volunteers 2 hours after hydrogen fluoride exposure.

Lund K, Dunster C, Ramis I, Sandström T, Kelly FJ, Søstrand P, Schwarze P, Skovlund E, Boe J, Kongerud J, Refsnes M.

Hum Exp Toxicol. 2005 Mar;24(3):101-8.

PMID:
15901049
33.

New water-soluble sulfonylphosphoramidic acid derivatives of the COX-2 selective inhibitor cimicoxib. A novel approach to sulfonamide prodrugs.

Almansa C, Bartrolí J, Belloc J, Cavalcanti FL, Ferrando R, Gómez LA, Ramis I, Carceller E, Merlos M, García-Rafanell J.

J Med Chem. 2004 Oct 21;47(22):5579-82.

PMID:
15481993
34.

The intestinal anti-inflammatory activity of UR-12746S on reactivated experimental colitis is mediated through downregulation of cytokine production.

Gálvez J, Garrido M, Rodríguez-Cabezas ME, Ramis I, de Medina FS, Merlos M, Zarzuelo A.

Inflamm Bowel Dis. 2003 Nov;9(6):363-71.

PMID:
14671485
35.

Human exposure to hydrogen fluoride induces acute neutrophilic, eicosanoid, and antioxidant changes in nasal lavage fluid.

Lund K, Refsnes M, Ramis I, Dunster C, Boe J, Schwarze PE, Skovlund E, Kelly FJ, Kongerud J.

Inhal Toxicol. 2002 Feb;14(2):119-32.

PMID:
12122575
36.

Constitutive nuclear factor-kappaB activity in human upper airway tissues and nasal epithelial cells.

Ramis I, Bioque G, Lorente J, Jares P, Quesada P, Roselló-Catafau J, Gelpí E, Bulbena O.

Eur Respir J. 2000 Mar;15(3):582-9.

37.

[Nitric oxide synthase activity in nasal mucosa].

Lorente J, Quesada JL, Quesada P, Serra J, Piñas J, Bulbena O, Ramis I.

Acta Otorrinolaringol Esp. 1998 Oct;49(7):503-7. Spanish.

PMID:
9866213
38.

The assessment of biomarkers to detect nephrotoxicity using an integrated database.

Taylor SA, Chivers ID, Price RG, Arce-Tomas M, Milligan P, Francini I, Alinovi R, Cavazzini S, Bergamaschi E, Vittori M, Mutti A, Lauwerys RR, Bernard AM, Roels HA, De Broe ME, Nuyts GD, Elseviers MM, Hotter G, Ramis I, Rosello J, Gelpi E, Stolte H, Eisenberger U, Fels LM.

Environ Res. 1997 Oct;75(1):23-33.

PMID:
9356191
39.

Development and validation of new screening tests for nephrotoxic effects.

Price RG, Taylor SA, Chivers I, Arce-Tomas M, Crutcher E, Franchini I, Alinovi R, Cavazzini S, Bergamaschi E, Mutti A, Vettori MV, Lauwerys R, Bernard A, Kabanda A, Roels H, Thielemans N, Hotz P, De Broe ME, Elseviers MM, Nuyts GD, Gelpi E, Hotter G, Rosello J, Ramis I, Stolte H, et al.

Hum Exp Toxicol. 1996 Mar;15 Suppl 1:S10-9. Review.

PMID:
8882556
40.

Differential activity of nitric oxide synthase in human nasal mucosa and polyps.

Ramis I, Lorente J, Roselló-Catafau J, Quesada P, Gelpí E, Bulbena O.

Eur Respir J. 1996 Feb;9(2):202-6.

41.

Interleukin-3 in bronchial biopsies from nonasthmatics and patients with mild and allergen-induced asthma.

Woolley KL, Adelroth E, Woolley MJ, Ramis I, Abrams JS, Jordana M, O'Byrne PM.

Am J Respir Crit Care Med. 1996 Jan;153(1):350-5.

PMID:
8542142
42.

In vitro release of arachidonic acid metabolites, glutathione peroxidase, and oxygen-free radicals from platelets of asthmatic patients with and without aspirin intolerance.

Plaza V, Prat J, Rosellò J, Ballester E, Ramis I, Mullol J, Gelpí E, Vives-Corrons JL, Picado C.

Thorax. 1995 May;50(5):490-6.

43.

Increased survival of nasal polyp eosinophils.

Ramis I, Finotto S, Dolovich J, Marshall J, Jordana M.

Immunol Lett. 1995 Mar;45(3):219-21. No abstract available.

PMID:
7558178
44.

Immune-inflammatory functions of fibroblasts.

Jordana M, Särnstrand B, Sime PJ, Ramis I.

Eur Respir J. 1994 Dec;7(12):2212-22. Review.

45.

Application of totally automated on-line sample clean up system for extraction and high-performance liquid chromatography separation of peptide leukotrienes.

Ramis I, Hotter G, Roselló-Catafau J, Bulbena O, Picado C, Gelpi E.

J Pharm Biomed Anal. 1993 Nov-Dec;11(11-12):1135-9.

PMID:
8123725
46.

Altered leukotriene B4 levels by HL-60 cells after monocytic/macrophage differentiation.

Hotter G, Ramis I, Closa D, Roselló-Catafau J, Gelpí E.

Agents Actions. 1993 Sep;40(1-2):72-7.

PMID:
8147272
47.

Release of chemical mediators and inflammatory cell influx during early allergic reaction in the nose: effect of furosemide.

Prat J, Mullol J, Ramis I, Roselló-Catafau J, Xaubet A, Nerin I, Gelpí E, Picado C.

J Allergy Clin Immunol. 1993 Aug;92(2):248-54.

PMID:
8349935
48.

Failure of frusemide to increase production of prostaglandin E2 in human nasal mucosa in vivo.

Mullol J, Ramis I, Prat J, Roselló-Catafau J, Xaubet A, Piera C, Gelpí E, Picado C.

Thorax. 1993 Mar;48(3):260-3.

49.

Markers of early renal changes induced by industrial pollutants. III. Application to workers exposed to cadmium.

Roels H, Bernard AM, Cárdenas A, Buchet JP, Lauwerys RR, Hotter G, Ramis I, Mutti A, Franchini I, Bundschuh I, et al.

Br J Ind Med. 1993 Jan;50(1):37-48.

50.

Markers of early renal changes induced by industrial pollutants. II. Application to workers exposed to lead.

Cárdenas A, Roels H, Bernard AM, Barbon R, Buchet JP, Lauwerys RR, Roselló J, Ramis I, Mutti A, Franchini I, et al.

Br J Ind Med. 1993 Jan;50(1):28-36.

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