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Recurrent Wheezing During the First 3 Years of Life in a Birth Cohort of Moderate-to-Late Preterm Infants.

Moreno-Galdó A, Pérez-Yarza EG, Ramilo O, Rubí T, Escribano A, Torres A, Sardón O, Oliva C, Pérez G, Cortell I, Rovira-Amigo S, Sánchez-Solís M, Pérez-Frías J, Velasco V, Torres J, Figuerola J, Barrio MI, García-Hernández G, Mejías A; SAREPREM 3235 investigators.

Pediatr Allergy Immunol. 2019 Oct 9. doi: 10.1111/pai.13134. [Epub ahead of print]


Risk of Childhood Wheeze and Asthma after Respiratory Syncytial Virus Infection in Full-Term Infants.

Mejias A, Bingcao W, Tandon N, Chow W, Varma R, Franco E, Ramilo O.

Pediatr Allergy Immunol. 2019 Sep 30. doi: 10.1111/pai.13131. [Epub ahead of print]


Advanced Live Attenuated Vaccines for the Prevention of Respiratory Syncytial Virus Infections in Young Children.

Ramilo O, Rodriguez-Fernandez R, Peeples ME, Mejias A.

J Infect Dis. 2019 Sep 24. pii: jiz409. doi: 10.1093/infdis/jiz409. [Epub ahead of print] No abstract available.


Whole-blood transcriptomic responses to lumacaftor/ivacaftor therapy in cystic fibrosis.

Kopp BT, Fitch J, Jaramillo L, Shrestha CL, Robledo-Avila F, Zhang S, Palacios S, Woodley F, Hayes D Jr, Partida-Sanchez S, Ramilo O, White P, Mejias A.

J Cyst Fibros. 2019 Aug 29. pii: S1569-1993(19)30868-9. doi: 10.1016/j.jcf.2019.08.021. [Epub ahead of print]


Efficacy of a Clinical Prediction Rule to Identify Febrile Young Infants at Low Risk for Serious Bacterial Infections-Reply.

Kuppermann N, Mahajan P, Ramilo O.

JAMA Pediatr. 2019 Aug 19. doi: 10.1001/jamapediatrics.2019.2656. [Epub ahead of print] No abstract available.


Respiratory Syncytial Virus Vaccines: Are We Making Progress?

Mejias A, Rodriguez-Fernandez R, Peeples ME, Ramilo O.

Pediatr Infect Dis J. 2019 Oct;38(10):e266-e269. doi: 10.1097/INF.0000000000002404. No abstract available.


Infant Immune Response to Respiratory Viral Infections.

Heinonen S, Rodriguez-Fernandez R, Diaz A, Rodriguez-Pastor SO, Ramilo O, Mejias A.

Immunol Allergy Clin North Am. 2019 Aug;39(3):361-376. doi: 10.1016/j.iac.2019.03.005. Epub 2019 May 15. Review.


Recent Trends in RSV Immunoprophylaxis: Clinical Implications for the Infant.

Acero-Bedoya S, Wozniak PS, Sánchez PJ, Ramilo O, Mejias A.

Am J Perinatol. 2019 Jul;36(S 02):S63-S67. doi: 10.1055/s-0039-1691803. Epub 2019 Jun 25.


Community-Acquired Pneumonia in Children: Myths and Facts.

Yun KW, Wallihan R, Juergensen A, Mejias A, Ramilo O.

Am J Perinatol. 2019 Jul;36(S 02):S54-S57. doi: 10.1055/s-0039-1691801. Epub 2019 Jun 25.


Viral Bacterial Interactions in Children: Impact on Clinical Outcomes.

Diaz-Diaz A, Garcia-Maurino C, Jordan-Villegas A, Naples J, Ramilo O, Mejias A.

Pediatr Infect Dis J. 2019 Jun;38(6S Suppl 1):S14-S19. doi: 10.1097/INF.0000000000002319.



Curtis N, Finn A, Warris A, Pollard AJ, van Rossum A, Ramilo O.

Pediatr Infect Dis J. 2019 Jun;38(6S Suppl 1):S1. doi: 10.1097/INF.0000000000002316. No abstract available.


Prediction Models for Febrile Infants: Time for a Unified Field Theory.

Kuppermann N, Mahajan P, Ramilo O.

Pediatrics. 2019 Jul;144(1). pii: e20191375. doi: 10.1542/peds.2019-1375. Epub 2019 Jun 5. No abstract available.


[Disseminated cat scratch disease: The wide variety of clinical presentations].

Maiques-Tobias E, Tomatis-Souverbielle C, Watson J, Ramilo O, Mejias A.

An Pediatr (Barc). 2019 Jun;90(6):393-395. doi: 10.1016/j.anpedi.2018.06.002. Epub 2018 Jul 7. Spanish. No abstract available.


Practice Variation in the Evaluation and Disposition of Febrile Infants ≤60 Days of Age.

Rogers AJ, Kuppermann N, Anders J, Roosevelt G, Hoyle JD Jr, Ruddy RM, Bennett JE, Borgialli DA, Dayan PS, Powell EC, Casper TC, Ramilo O, Mahajan P; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN).

J Emerg Med. 2019 Jun;56(6):583-591. doi: 10.1016/j.jemermed.2019.03.003. Epub 2019 Apr 20.


Respiratory Syncytial Virus, Rhinoviruses, and Recurrent Wheezing: Unraveling the Riddle Opens New Opportunities for Targeted Interventions.

Ramilo O, Rodriguez-Fernandez R, Mejias A.

JAMA Pediatr. 2019 Jun 1;173(6):520-521. doi: 10.1001/jamapediatrics.2019.0370. No abstract available.


Multiple sites PCR testing for enteroviruses in young febrile infants.

Tomatis Souverbielle C, Feister J, Leber A, Salamon D, Mejias A, Ramilo O, Erdem G.

Lancet Infect Dis. 2019 Mar;19(3):239-240. doi: 10.1016/S1473-3099(19)30042-8. No abstract available.


A Clinical Prediction Rule to Identify Febrile Infants 60 Days and Younger at Low Risk for Serious Bacterial Infections.

Kuppermann N, Dayan PS, Levine DA, Vitale M, Tzimenatos L, Tunik MG, Saunders M, Ruddy RM, Roosevelt G, Rogers AJ, Powell EC, Nigrovic LE, Muenzer J, Linakis JG, Grisanti K, Jaffe DM, Hoyle JD Jr, Greenberg R, Gattu R, Cruz AT, Crain EF, Cohen DM, Brayer A, Borgialli D, Bonsu B, Browne L, Blumberg S, Bennett JE, Atabaki SM, Anders J, Alpern ER, Miller B, Casper TC, Dean JM, Ramilo O, Mahajan P; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN).

JAMA Pediatr. 2019 Apr 1;173(4):342-351. doi: 10.1001/jamapediatrics.2018.5501.


Secondhand smoke alters arachidonic acid metabolism and inflammation in infants and children with cystic fibrosis.

Kopp BT, Thompson R, Kim J, Konstan R, Diaz A, Smith B, Shrestha C, Rogers LK, Hayes D Jr, Tumin D, Woodley FW, Ramilo O, Sanders DB, Groner JA, Mejias A.

Thorax. 2019 Mar;74(3):237-246. doi: 10.1136/thoraxjnl-2018-211845. Epub 2019 Jan 19.


Molecular Distance to Health Transcriptional Score and Disease Severity in Children Hospitalized With Community-Acquired Pneumonia.

Wallihan RG, Suárez NM, Cohen DM, Marcon M, Moore-Clingenpeel M, Mejias A, Ramilo O.

Front Cell Infect Microbiol. 2018 Oct 30;8:382. doi: 10.3389/fcimb.2018.00382. eCollection 2018.


Viral Load Dynamics and Clinical Disease Severity in Infants With Respiratory Syncytial Virus Infection.

Garcia-Mauriño C, Moore-Clingenpeel M, Thomas J, Mertz S, Cohen DM, Ramilo O, Mejias A.

J Infect Dis. 2019 Apr 8;219(8):1207-1215. doi: 10.1093/infdis/jiy655.


Re: "Discharge Criteria for Bronchiolitis: Does Age Matter?"

Garcia-Mauriño C, Moore-Clingenpeel M, Ramilo O, Mejias A.

Pediatr Infect Dis J. 2018 Dec;37(12):e350-e351. doi: 10.1097/INF.0000000000002065. No abstract available.


Post-viral atopic airway disease: pathogenesis and potential avenues for intervention.

Hussain SA, Mejias A, Ramilo O, Peeples ME, Grayson MH.

Expert Rev Clin Immunol. 2019 Jan;15(1):49-58. doi: 10.1080/1744666X.2019.1541737. Epub 2018 Nov 3.


Risk of Serious Bacterial Infection in Infants Aged ≤60 Days Presenting to Emergency Departments with a History of Fever Only.

Ramgopal S, Janofsky S, Zuckerbraun NS, Ramilo O, Mahajan P, Kuppermann N, Vitale MA.

J Pediatr. 2019 Jan;204:191-195. doi: 10.1016/j.jpeds.2018.08.043. Epub 2018 Oct 2.


Risk of Bacterial Coinfections in Febrile Infants 60 Days Old and Younger with Documented Viral Infections.

Mahajan P, Browne LR, Levine DA, Cohen DM, Gattu R, Linakis JG, Anders J, Borgialli D, Vitale M, Dayan PS, Casper TC, Ramilo O, Kuppermann N; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN).

J Pediatr. 2018 Dec;203:86-91.e2. doi: 10.1016/j.jpeds.2018.07.073. Epub 2018 Sep 6.


The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates.

Mazur NI, Higgins D, Nunes MC, Melero JA, Langedijk AC, Horsley N, Buchholz UJ, Openshaw PJ, McLellan JS, Englund JA, Mejias A, Karron RA, Simões EA, Knezevic I, Ramilo O, Piedra PA, Chu HY, Falsey AR, Nair H, Kragten-Tabatabaie L, Greenough A, Baraldi E, Papadopoulos NG, Vekemans J, Polack FP, Powell M, Satav A, Walsh EE, Stein RT, Graham BS, Bont LJ; Respiratory Syncytial Virus Network (ReSViNET) Foundation.

Lancet Infect Dis. 2018 Oct;18(10):e295-e311. doi: 10.1016/S1473-3099(18)30292-5. Epub 2018 Jun 18. Review. Erratum in: Lancet Infect Dis. 2018 Jul 25;:.


Respiratory Syncytial Virus-induced Acute Disease Severity and Long-Term Wheezing. Uncovering the Unexpected.

Ramilo O, Mejias A.

Am J Respir Crit Care Med. 2018 Oct 15;198(8):984-986. doi: 10.1164/rccm.201805-0908ED. No abstract available.


Whole blood transcriptional profiles as a prognostic tool in complete and incomplete Kawasaki Disease.

Jaggi P, Mejias A, Xu Z, Yin H, Moore-Clingenpeel M, Smith B, Burns JC, Tremoulet AH, Jordan-Villegas A, Chaussabel D, Texter K, Pascual V, Ramilo O.

PLoS One. 2018 May 29;13(5):e0197858. doi: 10.1371/journal.pone.0197858. eCollection 2018.


Early Immune Function and Duration of Organ Dysfunction in Critically III Children with Sepsis.

Muszynski JA, Nofziger R, Moore-Clingenpeel M, Greathouse K, Anglim L, Steele L, Hensley J, Hanson-Huber L, Nateri J, Ramilo O, Hall MW.

Am J Respir Crit Care Med. 2018 Aug 1;198(3):361-369. doi: 10.1164/rccm.201710-2006OC.


Respiratory Syncytial Virus Seasonality: A Global Overview.

Obando-Pacheco P, Justicia-Grande AJ, Rivero-Calle I, Rodríguez-Tenreiro C, Sly P, Ramilo O, Mejías A, Baraldi E, Papadopoulos NG, Nair H, Nunes MC, Kragten-Tabatabaie L, Heikkinen T, Greenough A, Stein RT, Manzoni P, Bont L, Martinón-Torres F.

J Infect Dis. 2018 Apr 11;217(9):1356-1364. doi: 10.1093/infdis/jiy056. Review.


Accuracy of the Urinalysis for Urinary Tract Infections in Febrile Infants 60 Days and Younger.

Tzimenatos L, Mahajan P, Dayan PS, Vitale M, Linakis JG, Blumberg S, Borgialli D, Ruddy RM, Van Buren J, Ramilo O, Kuppermann N; Pediatric Emergency Care Applied Research Network (PECARN).

Pediatrics. 2018 Feb;141(2). pii: e20173068. doi: 10.1542/peds.2017-3068. Epub 2018 Jan 16.


One Step Forward in the Road Toward a Universal Influenza Vaccine.

Ramilo O, Rodriguez-Fernandez R, Mejias A.

J Infect Dis. 2017 Dec 27;217(1):1-2. doi: 10.1093/infdis/jix591. No abstract available.


Discharge Criteria for Bronchiolitis: An Unmet Need.

Garcia-Mauriño C, Moore-Clingenpeel M, Wallihan R, Koranyi K, Rajah B, Shirk T, Vegh M, Ramilo O, Mejias A.

Pediatr Infect Dis J. 2018 Jun;37(6):514-519. doi: 10.1097/INF.0000000000001836.


Respiratory Syncytial Virus Genotypes, Host Immune Profiles, and Disease Severity in Young Children Hospitalized With Bronchiolitis.

Rodriguez-Fernandez R, Tapia LI, Yang CF, Torres JP, Chavez-Bueno S, Garcia C, Jaramillo LM, Moore-Clingenpeel M, Jafri HS, Peeples ME, Piedra PA, Ramilo O, Mejias A.

J Infect Dis. 2017 Dec 27;217(1):24-34. doi: 10.1093/infdis/jix543.


Prefusion F, Postfusion F, G Antibodies, and Disease Severity in Infants and Young Children With Acute Respiratory Syncytial Virus Infection.

Capella C, Chaiwatpongsakorn S, Gorrell E, Risch ZA, Ye F, Mertz SE, Johnson SM, Moore-Clingenpeel M, Ramilo O, Mejias A, Peeples ME.

J Infect Dis. 2017 Dec 12;216(11):1398-1406. doi: 10.1093/infdis/jix489.


Epidemiology of Bacteremia in Febrile Infants Aged 60 Days and Younger.

Powell EC, Mahajan PV, Roosevelt G, Hoyle JD Jr, Gattu R, Cruz AT, Rogers AJ, Atabaki SM, Jaffe DM, Casper TC, Ramilo O, Kuppermann N; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN).

Ann Emerg Med. 2018 Feb;71(2):211-216. doi: 10.1016/j.annemergmed.2017.07.488. Epub 2017 Oct 6.


Global respiratory syncytial virus-associated mortality in young children (RSV GOLD): a retrospective case series.

Scheltema NM, Gentile A, Lucion F, Nokes DJ, Munywoki PK, Madhi SA, Groome MJ, Cohen C, Moyes J, Thorburn K, Thamthitiwat S, Oshitani H, Lupisan SP, Gordon A, Sánchez JF, O'Brien KL; PERCH Study Group, Gessner BD, Sutanto A, Mejias A, Ramilo O, Khuri-Bulos N, Halasa N, de-Paris F, Pires MR, Spaeder MC, Paes BA, Simões EAF, Leung TF, da Costa Oliveira MT, de Freitas Lázaro Emediato CC, Bassat Q, Butt W, Chi H, Aamir UB, Ali A, Lucero MG, Fasce RA, Lopez O, Rath BA, Polack FP, Papenburg J, Roglić S, Ito H, Goka EA, Grobbee DE, Nair H, Bont LJ.

Lancet Glob Health. 2017 Oct;5(10):e984-e991. doi: 10.1016/S2214-109X(17)30344-3. Erratum in: Lancet Glob Health. 2017 Dec;5(12 ):e1190.


Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections.

Cruz AT, Mahajan P, Bonsu BK, Bennett JE, Levine DA, Alpern ER, Nigrovic LE, Atabaki SM, Cohen DM, VanBuren JM, Ramilo O, Kuppermann N; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network.

JAMA Pediatr. 2017 Nov 6;171(11):e172927. doi: 10.1001/jamapediatrics.2017.2927. Epub 2017 Nov 6. Erratum in: JAMA Pediatr. 2018 Mar 1;172(3):302.


Effects of prior influenza virus vaccination on maternal antibody responses: Implications for achieving protection in the newborns.

Christian LM, Beverly C, Mitchell AM, Karlsson E, Porter K, Schultz-Cherry S, Ramilo O.

Vaccine. 2017 Sep 18;35(39):5283-5290. doi: 10.1016/j.vaccine.2017.05.050. Epub 2017 Aug 1.


The Yale Observation Scale Score and the Risk of Serious Bacterial Infections in Febrile Infants.

Nigrovic LE, Mahajan PV, Blumberg SM, Browne LR, Linakis JG, Ruddy RM, Bennett JE, Rogers AJ, Tzimenatos L, Powell EC, Alpern ER, Casper TC, Ramilo O, Kuppermann N; Febrile Infant Working Group of the Pediatric Emergency Care Applied Research Network (PECARN).

Pediatrics. 2017 Jul;140(1). pii: e20170695. doi: 10.1542/peds.2017-0695. Epub 2017 Jun 6.


Rhinovirus - not just the common cold.

Drysdale SB, Mejias A, Ramilo O.

J Infect. 2017 Jun;74 Suppl 1:S41-S46. doi: 10.1016/S0163-4453(17)30190-1. Review.



Curtis N, Pollard AJ, Finn A, Ramilo O, Dobson S, Warris A, van Rossum A.

J Infect. 2017 Jun;74 Suppl 1:S1. doi: 10.1016/S0163-4453(17)30183-4. No abstract available.


Host transcriptomics for diagnosis of infectious diseases: one step closer to clinical application.

Ramilo O, Mejias A.

Eur Respir J. 2017 Jun 15;49(6). pii: 1700993. doi: 10.1183/13993003.00993-2017. Print 2017 Jun. No abstract available.


RNA signature test to distinguish bacterial from viral infection.

Ramilo O, Mejias A, Mahajan P, Kuppermann N.

J Pediatr. 2017 Mar;182:401-404. doi: 10.1016/j.jpeds.2016.12.066. No abstract available.



Mejias A, Sánchez PJ, Ramilo O.

J Pediatr. 2017 Jun;185:251. doi: 10.1016/j.jpeds.2017.01.055. Epub 2017 Feb 22. No abstract available.


Impact of the Updated Guidance for Palivizumab Prophylaxis against Respiratory Syncytial Virus Infection: A Single Center Experience.

Rajah B, Sánchez PJ, Garcia-Maurino C, Leber A, Ramilo O, Mejias A.

J Pediatr. 2017 Feb;181:183-188.e1. doi: 10.1016/j.jpeds.2016.10.074. Epub 2016 Nov 15.


Nasopharyngeal Microbiota, Host Transcriptome, and Disease Severity in Children with Respiratory Syncytial Virus Infection.

de Steenhuijsen Piters WA, Heinonen S, Hasrat R, Bunsow E, Smith B, Suarez-Arrabal MC, Chaussabel D, Cohen DM, Sanders EA, Ramilo O, Bogaert D, Mejias A.

Am J Respir Crit Care Med. 2016 Nov 1;194(9):1104-1115.


Helicobacter pylori Infection Is Associated with Decreased Expression of SLC5A8, a Cancer Suppressor Gene, in Young Children.

Orellana-Manzano A, O'Ryan MG, Lagomarcino AJ, George S, Muñoz MS, Mamani N, Serrano CA, Harris PR, Ramilo O, Mejías A, Torres JP, Lucero Y, Quest AF.

Front Cell Infect Microbiol. 2016 Oct 10;6:121. eCollection 2016.


Promise and Limitations of Procalcitonin to Identify Bacterial Infections in the Pediatric Intensive Care Unit.

Ramilo O, Rodriguez-Fernandez R, Mejias A.

J Pediatr. 2016 Dec;179:7-9. doi: 10.1016/j.jpeds.2016.09.031. Epub 2016 Oct 4. No abstract available.


Development and clinical applications of novel antibodies for prevention and treatment of respiratory syncytial virus infection.

Mejias A, Garcia-Maurino C, Rodriguez-Fernandez R, Peeples ME, Ramilo O.

Vaccine. 2017 Jan 11;35(3):496-502. doi: 10.1016/j.vaccine.2016.09.026. Epub 2016 Sep 28. Review.


Association of RNA Biosignatures With Bacterial Infections in Febrile Infants Aged 60 Days or Younger.

Mahajan P, Kuppermann N, Mejias A, Suarez N, Chaussabel D, Casper TC, Smith B, Alpern ER, Anders J, Atabaki SM, Bennett JE, Blumberg S, Bonsu B, Borgialli D, Brayer A, Browne L, Cohen DM, Crain EF, Cruz AT, Dayan PS, Gattu R, Greenberg R, Hoyle JD Jr, Jaffe DM, Levine DA, Lillis K, Linakis JG, Muenzer J, Nigrovic LE, Powell EC, Rogers AJ, Roosevelt G, Ruddy RM, Saunders M, Tunik MG, Tzimenatos L, Vitale M, Dean JM, Ramilo O; Pediatric Emergency Care Applied Research Network (PECARN).

JAMA. 2016 Aug 23-30;316(8):846-57. doi: 10.1001/jama.2016.9207. Erratum in: JAMA. 2016 Nov 8;316(18):1924.

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