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Introduction to Topical Collection on Updates in Advanced Heart Failure.

Rame JE.

Curr Heart Fail Rep. 2019 Oct;16(5):117-118. doi: 10.1007/s11897-019-00439-w. Review. No abstract available.


Self-Expanding Valve System for Treatment of Native Aortic Regurgitation by Transcatheter Aortic Valve Implantation (from the STS/ACC TVT Registry).

Anwaruddin S, Desai ND, Szeto WY, Hermiller JB Jr, Sorajja P, Kodali S, Popma JJ, Giri J, Herrmann HC, Tang GHL, Rame JE, McCarthy FH, Zhang AQ, Reardon MJ.

Am J Cardiol. 2019 Sep 1;124(5):781-788. doi: 10.1016/j.amjcard.2019.05.045. Epub 2019 Jun 6.


Preimplant Phosphodiesterase-5 Inhibitor Use Is Associated With Higher Rates of Severe Early Right Heart Failure After Left Ventricular Assist Device Implantation.

Gulati G, Grandin EW, Kennedy K, Cabezas F, DeNofrio DD, Kociol R, Rame JE, Pagani FD, Kirklin JK, Kormos RL, Teuteberg J, Kiernan M.

Circ Heart Fail. 2019 Jun;12(6):e005537. doi: 10.1161/CIRCHEARTFAILURE.118.005537. Epub 2019 Jun 11.


Optimal timing for heart transplantation in patients bridged with left ventricular assist devices: Is timing of the essence?

Brown CR, Khurshan F, Chen Z, Groeneveld PW, McCarthy F, Acker M, Rame JE, Desai N.

J Thorac Cardiovasc Surg. 2019 Jun;157(6):2315-2324.e4. doi: 10.1016/j.jtcvs.2018.12.118. Epub 2019 Mar 1.


Better With Time: An Economic Assessment of Long-Term Mechanical Circulatory Support in a Population Surviving at Least 1 Year with a Left Ventricular Assist Device.

Chung JJ, Stetson R, Gordon J, Chen CW, Gaffey AC, Rame JE, Acker M, Atluri P.

Semin Thorac Cardiovasc Surg. 2018 Oct 9. pii: S1043-0679(18)30292-2. doi: 10.1053/j.semtcvs.2018.09.029. [Epub ahead of print]


Frameshifts in Code and in Care: The Importance of Timely Genetic Evaluation.

Reza N, Chowns JL, Merrill SL, Marzolf A, Zado ES, Palmer MB, Deshpande C, Pryma DA, Rame JE, Marchlinski FE, Owens AT.

Circ Genom Precis Med. 2018 May;11(5):e002215. doi: 10.1161/CIRCGEN.118.002215. No abstract available.


Pulmonary hypertension: Barrier or just a bump in the road in transplanting adults with congenital heart disease.

Menachem JN, Birati EY, Zamani P, Owens AT, Atluri P, Bermudez CA, Drajpuch D, Fuller S, Kim YY, Mascio CE, Palanivel V, Rame JE, Wald J, Acker MA, Mazurek JA.

Congenit Heart Dis. 2018 Jul;13(4):492-498. doi: 10.1111/chd.12606. Epub 2018 Mar 30. Review.


Predicting Long Term Outcome in Patients Treated With Continuous Flow Left Ventricular Assist Device: The Penn-Columbia Risk Score.

Birati EY, Hanff TC, Maldonado D, Grandin EW, Kennel PJ, Mazurek JA, Vorovich E, Seigerman M, Howard JLL, Acker MA, Naka Y, Wald J, Goldberg LR, Jessup M, Atluri P, Margulies KB, Schulze PC, Rame JE.

J Am Heart Assoc. 2018 Mar 7;7(6). pii: e006408. doi: 10.1161/JAHA.117.006408.


Transfemoral transcatheter aortic valve replacement with a self-expanding valve for severe aortic regurgitation in a patient with left ventricular assist device.

Rene AG, Desai N, Wald J, Rame JE, Frogel JK, Anwaruddin S.

J Card Surg. 2017 Nov;32(11):741-745. doi: 10.1111/jocs.13238. Epub 2017 Nov 26.


Biventricular Support With Intracorporeal, Continuous Flow, Centrifugal Ventricular Assist Devices.

Arabía FA, Milano CA, Mahr C, McGee EC Jr, Mokadam NA, Rame JE, Moriguchi JD, Ramzy D, Naftel DC, Myers SL, Kirklin JK.

Ann Thorac Surg. 2018 Feb;105(2):548-555. doi: 10.1016/j.athoracsur.2017.08.019. Epub 2017 Nov 20.


Early Right Ventricular Assist Device Use in Patients Undergoing Continuous-Flow Left Ventricular Assist Device Implantation: Incidence and Risk Factors From the Interagency Registry for Mechanically Assisted Circulatory Support.

Kiernan MS, Grandin EW, Brinkley M Jr, Kapur NK, Pham DT, Ruthazer R, Rame JE, Atluri P, Birati EY, Oliveira GH, Pagani FD, Kirklin JK, Naftel D, Kormos RL, Teuteberg JJ, DeNofrio D.

Circ Heart Fail. 2017 Oct;10(10). pii: e003863. doi: 10.1161/CIRCHEARTFAILURE.117.003863.


Different Clinical Course and Complications in Interagency Registry for Mechanically Assisted Circulatory Support 1 (INTERMACS) Patients Managed With or Without Extracorporeal Membrane Oxygenation.

Han JJ, Chung J, Chen CW, Gaffey AC, Sotolongo A, Justice C, Ameer AE, Rame JE, Bermudez C, Acker MA, Atluri P.

ASAIO J. 2018 May/Jun;64(3):318-322. doi: 10.1097/MAT.0000000000000674.


Outcomes of rescue cardiopulmonary support for periprocedural acute hemodynamic decompensation in patients undergoing catheter ablation of electrical storm.

Enriquez A, Liang J, Gentile J, Schaller RD, Supple GE, Frankel DS, Garcia FC, Wald J, Birati EY, Rame JE, Bermudez C, Callans DJ, Marchlinski FE, Santangeli P.

Heart Rhythm. 2018 Jan;15(1):75-80. doi: 10.1016/j.hrthm.2017.09.005. Epub 2017 Sep 14.


Value of a flow cytometry cross-match in the setting of a negative complement-dependent cytotoxicity cross-match in heart transplant recipients.

Keeshan BC, O'Connor MJ, Lin KY, Monos D, Lind C, Mascio CE, Rame JE, Spray TL, Shaddy RE, Rossano JW.

Clin Transplant. 2017 Oct;31(10). doi: 10.1111/ctr.13064. Epub 2017 Aug 30.


Subcellular Remodeling of the T-Tubule Membrane System: The Limits of Myocardial Recovery Revealed?

Rame JE, Lavandero S.

Circulation. 2017 Apr 25;135(17):1646-1650. doi: 10.1161/CIRCULATIONAHA.117.025319. No abstract available.


Management of Ventricular Arrhythmias in Patients With Advanced Heart Failure.

Santangeli P, Rame JE, Birati EY, Marchlinski FE.

J Am Coll Cardiol. 2017 Apr 11;69(14):1842-1860. doi: 10.1016/j.jacc.2017.01.047. Review.


Higher Body Mass Index Increases Risk of HeartMate II Pump Thrombosis But Does Not Adversely Affect Long-Term Survival.

Han JJ, Sooppan R, Johnson AP, Chen CW, Gaffey AC, Phillips EC, Howard J, Rame JE, Acker MA, Atluri P.

Circ J. 2017 Jan 25;81(2):213-219. doi: 10.1253/circj.CJ-16-0942. Epub 2016 Dec 22.


Heart Rate Dependence of the Pulmonary Resistance x Compliance (RC) Time and Impact on Right Ventricular Load.

Metkus TS, Mullin CJ, Grandin EW, Rame JE, Tampakakis E, Hsu S, Kolb TM, Damico R, Hassoun PM, Kass DA, Mathai SC, Tedford RJ.

PLoS One. 2016 Nov 18;11(11):e0166463. doi: 10.1371/journal.pone.0166463. eCollection 2016.


INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) Profiling Identifies Ambulatory Patients at High Risk on Medical Therapy After Hospitalizations for Heart Failure.

Stewart GC, Kittleson MM, Patel PC, Cowger JA, Patel CB, Mountis MM, Johnson FL, Guglin ME, Rame JE, Teuteberg JJ, Stevenson LW.

Circ Heart Fail. 2016 Nov;9(11). pii: e003032.


Relation of Body Mass Index to Long-Term Survival After Cardiac Resynchronization Therapy.

Grandin EW, Wand A, Zamani P, Rame JE, Verdino RJ.

Am J Cardiol. 2016 Dec 15;118(12):1861-1867. doi: 10.1016/j.amjcard.2016.08.079. Epub 2016 Sep 15.


Metabolic Reprogramming After Left Ventricular Assist Device: Remodeling Without Recovery of Cardiac Energetics.

Rame JE, Birks EJ.

JACC Basic Transl Sci. 2016 Oct 31;1(6):445-448. doi: 10.1016/j.jacbts.2016.09.003. eCollection 2016 Oct. No abstract available.


Right Ventricular Pacing-Induced Hemodynamic Compromise in a Patient With a Left Ventricular Assist Device.

Hyman MC, Schaller RD, Epstein AE, Rame JE.

Circ Arrhythm Electrophysiol. 2016 Nov;9(11). pii: e004622. No abstract available.


Cholesterol efflux capacity of high-density lipoprotein correlates with survival and allograft vasculopathy in cardiac transplant recipients.

Javaheri A, Molina M, Zamani P, Rodrigues A, Novak E, Chambers S, Stutman P, Maslanek W, Williams M, Lilly SM, Heeger P, Sayegh MH, Chandraker A, Briscoe DM, Daly KP, Starling R, Ikle D, Christie J, Rame JE, Goldberg LR, Billheimer J, Rader DJ.

J Heart Lung Transplant. 2016 Nov;35(11):1295-1302. doi: 10.1016/j.healun.2016.06.022. Epub 2016 Jul 15. Review.


Right ventricular response to pulsatile load is associated with early right heart failure and mortality after left ventricular assist device.

Grandin EW, Zamani P, Mazurek JA, Troutman GS, Birati EY, Vorovich E, Chirinos JA, Tedford RJ, Margulies KB, Atluri P, Rame JE.

J Heart Lung Transplant. 2017 Jan;36(1):97-105. doi: 10.1016/j.healun.2016.06.015. Epub 2016 Jun 24.


Comparison of Causes of Death After Heart Transplantation in Patients With Left Ventricular Ejection Fractions ≤35% Versus >35.

Birati EY, Mathelier H, Molina M, Hanff TC, Mazurek JA, Atluri P, Acker MA, Rame JE, Margulies KB, Goldberg LR, Jessup M.

Am J Cardiol. 2016 Apr 15;117(8):1322-6. doi: 10.1016/j.amjcard.2016.01.028. Epub 2016 Jan 28.


Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure.

Bedi KC Jr, Snyder NW, Brandimarto J, Aziz M, Mesaros C, Worth AJ, Wang LL, Javaheri A, Blair IA, Margulies KB, Rame JE.

Circulation. 2016 Feb 23;133(8):706-16. doi: 10.1161/CIRCULATIONAHA.115.017545. Epub 2016 Jan 27.


Metabolic Staging in Human Heart Failure: Circulating Acylcarnitines and the Failing Heart's Energetic Signature.

Rame JE.

J Am Coll Cardiol. 2016 Jan 26;67(3):300-2. doi: 10.1016/j.jacc.2015.11.017. No abstract available.


Reply: Is Pump the Answer to Heart Failure With Preserved Ejection Fraction?

Burkhoff D, Maurer MS, Joseph S, Rogers JG, Birati E, Rame JE, Shah SJ.

JACC Heart Fail. 2016 Jan;4(1):93. doi: 10.1016/j.jchf.2015.10.010. No abstract available.


HeartWare Left Ventricular Assist Device Pump Thrombosis: A Shift Away From Ramp.

Rame JE, Birati EY.

JACC Heart Fail. 2015 Nov;3(11):857-9. doi: 10.1016/j.jchf.2015.07.010. Epub 2015 Oct 7. No abstract available.


Reversible but risky: Pulmonary hypertension in advanced heart failure is the Achilles' heel of cardiac transplantation.

Bermudez CA, Rame JE.

J Thorac Cardiovasc Surg. 2015 Nov;150(5):1362-3. doi: 10.1016/j.jtcvs.2015.07.098. Epub 2015 Aug 6. No abstract available.


Who wants a left ventricular assist device for ambulatory heart failure? Early insights from the MEDAMACS screening pilot.

Stewart GC, Kittleson MM, Cowger JA, Johnson FL, Patel CB, Mountis MM, Patel PC, Rame JE, Testani J, Guglin ME, Teuteberg JJ, Stevenson LW.

J Heart Lung Transplant. 2015 Dec;34(12):1630-3. doi: 10.1016/j.healun.2015.07.009. Epub 2015 Aug 4. No abstract available.


Increasing Frequency of Left Ventricular Assist Device Exchanges in the United States.

McCarthy FH, Kobrin D, Rame JE, Groeneveld PW, McDermott KM, Atluri P, Acker MA, Desai ND.

Ann Thorac Surg. 2015 Nov;100(5):1660-4; discussion 1665. doi: 10.1016/j.athoracsur.2015.04.072. Epub 2015 Jul 21.


Ventricular assist devices for treatment of acute heart failure and chronic heart failure.

Kirkpatrick JN, Wieselthaler G, Strueber M, St John Sutton MG, Rame JE.

Heart. 2015 Jul;101(14):1091-6. doi: 10.1136/heartjnl-2014-306789. Epub 2015 May 6. Review.


Left atrial decompression pump for severe heart failure with preserved ejection fraction: theoretical and clinical considerations.

Burkhoff D, Maurer MS, Joseph SM, Rogers JG, Birati EY, Rame JE, Shah SJ.

JACC Heart Fail. 2015 Apr;3(4):275-82. doi: 10.1016/j.jchf.2014.10.011. Epub 2015 Mar 11.


Diagnosis and Management of LVAD Thrombosis.

Birati EY, Rame JE.

Curr Treat Options Cardiovasc Med. 2015 Feb;17(2):361. doi: 10.1007/s11936-014-0361-y.


Regulated inositol-requiring protein 1-dependent decay as a mechanism of corin RNA and protein deficiency in advanced human systolic heart failure.

Lee R, Xu B, Rame JE, Felkin LE, Barton P, Dries DL.

J Am Heart Assoc. 2014 Dec;3(6):e001104. doi: 10.1161/JAHA.114..


Acute hemodynamic decompensation during catheter ablation of scar-related ventricular tachycardia: incidence, predictors, and impact on mortality.

Santangeli P, Muser D, Zado ES, Magnani S, Khetpal S, Hutchinson MD, Supple G, Frankel DS, Garcia FC, Bala R, Riley MP, Lin D, Rame JE, Schaller R, Dixit S, Marchlinski FE, Callans DJ.

Circ Arrhythm Electrophysiol. 2015 Feb;8(1):68-75. doi: 10.1161/CIRCEP.114.002155. Epub 2014 Dec 9.


Disease progression in pulmonary arterial hypertension: refining the phenotype with a prognostic biomarker profile from collagen.

Rame JE, Vaidya A.

JACC Heart Fail. 2014 Aug;2(4):422-4. doi: 10.1016/j.jchf.2014.05.004. Epub 2014 Jul 9. No abstract available.


Post-heart transplant complications.

Birati EY, Rame JE.

Crit Care Clin. 2014 Jul;30(3):629-37. doi: 10.1016/j.ccc.2014.03.005. Review.


Left ventricular assist device management and complications.

Birati EY, Rame JE.

Crit Care Clin. 2014 Jul;30(3):607-27. doi: 10.1016/j.ccc.2014.04.001. Review.


Unexpected abrupt increase in left ventricular assist device thrombosis.

Rame JE, Atluri P, Acker MA.

N Engl J Med. 2014 Apr 10;370(15):1466-7. doi: 10.1056/NEJMc1402425. No abstract available.


Mesenchymal precursor cells as adjunctive therapy in recipients of contemporary left ventricular assist devices.

Ascheim DD, Gelijns AC, Goldstein D, Moye LA, Smedira N, Lee S, Klodell CT, Szady A, Parides MK, Jeffries NO, Skerrett D, Taylor DA, Rame JE, Milano C, Rogers JG, Lynch J, Dewey T, Eichhorn E, Sun B, Feldman D, Simari R, O'Gara PT, Taddei-Peters WC, Miller MA, Naka Y, Bagiella E, Rose EA, Woo YJ.

Circulation. 2014 Jun 3;129(22):2287-96. doi: 10.1161/CIRCULATIONAHA.113.007412. Epub 2014 Mar 28.


Dynamic left ventricular assist device inflow obstruction.

Birati EY, Kirkpatrick JN, Rame JE, Bala R, Margulies KB.

Circ Heart Fail. 2014 Jan;7(1):225-6. doi: 10.1161/CIRCHEARTFAILURE.113.000941. No abstract available.


Unexpected abrupt increase in left ventricular assist device thrombosis.

Starling RC, Moazami N, Silvestry SC, Ewald G, Rogers JG, Milano CA, Rame JE, Acker MA, Blackstone EH, Ehrlinger J, Thuita L, Mountis MM, Soltesz EG, Lytle BW, Smedira NG.

N Engl J Med. 2014 Jan 2;370(1):33-40. doi: 10.1056/NEJMoa1313385. Epub 2013 Nov 27.


Relation of regional fat distribution to left ventricular structure and function.

Neeland IJ, Gupta S, Ayers CR, Turer AT, Rame JE, Das SR, Berry JD, Khera A, McGuire DK, Vega GL, Grundy SM, de Lemos JA, Drazner MH.

Circ Cardiovasc Imaging. 2013 Sep;6(5):800-7. doi: 10.1161/CIRCIMAGING.113.000532. Epub 2013 Aug 8.


Complete spontaneous left heart and aortic thromboses on extracorporeal membrane oxygenation support.

Ramjee V, Shreenivas S, Rame JE, Kirkpatrick JN, Jagasia D.

Echocardiography. 2013 Nov;30(10):E342-3. doi: 10.1111/echo.12323. Epub 2013 Jul 27. No abstract available.


Ethical considerations related to the use of mechanical support in congenital heart disease.

Rossano JW, Kaufman BD, Rame JE.

World J Pediatr Congenit Heart Surg. 2013 Jan;4(1):70-4. doi: 10.1177/2150135112469040. Review.


Ventricular assist device implant in the elderly is associated with increased, but respectable risk: a multi-institutional study.

Atluri P, Goldstone AB, Kobrin DM, Cohen JE, MacArthur JW, Howard JL, Jessup ML, Rame JE, Acker MA, Woo YJ.

Ann Thorac Surg. 2013 Jul;96(1):141-7. doi: 10.1016/j.athoracsur.2013.04.010. Epub 2013 May 31.


Management of ventricular arrhythmias in patients with ventricular assist devices.

Pedrotty DM, Rame JE, Margulies KB.

Curr Opin Cardiol. 2013 May;28(3):360-8. doi: 10.1097/HCO.0b013e32835fb7dc. Review.


A pilot study of the effect of spironolactone therapy on exercise capacity and endothelial dysfunction in pulmonary arterial hypertension: study protocol for a randomized controlled trial.

Elinoff JM, Rame JE, Forfia PR, Hall MK, Sun J, Gharib AM, Abd-Elmoniem K, Graninger G, Harper B, Danner RL, Solomon MA.

Trials. 2013 Apr 2;14:91. doi: 10.1186/1745-6215-14-91.

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