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Items: 1 to 50 of 121

1.

Sphingosine Kinase 1/S1P Signaling Contributes to Pulmonary Fibrosis by Activating Hippo/YAP Pathway and Mitochondrial Reactive Oxygen Species in Lung Fibroblasts.

Huang LS, Sudhadevi T, Fu P, Punathil-Kannan PK, Ebenezer DL, Ramchandran R, Putherickal V, Cheresh P, Zhou G, Ha AW, Harijith A, Kamp DW, Natarajan V.

Int J Mol Sci. 2020 Mar 17;21(6). pii: E2064. doi: 10.3390/ijms21062064.

2.

S1P and Plasmalogen Derived Fatty Aldehydes in Cellular Signaling and Functions.

Ebenezer DL, Fu P, Ramchandran R, Ha AW, Putherickal V, Sudhadevi T, Harijith A, Schumacher F, Kleuser B, Natarajan V.

Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Mar 11:158681. doi: 10.1016/j.bbalip.2020.158681. [Epub ahead of print] Review. No abstract available.

PMID:
32171908
3.

ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis.

Chen C, Gupta P, Parashar D, Nair GG, George J, Geethadevi A, Wang W, Tsaih SW, Bradley W, Ramchandran R, Rader JS, Chaluvally-Raghavan P, Pradeep S.

Oncogene. 2020 Feb 6. doi: 10.1038/s41388-020-1194-7. [Epub ahead of print]

PMID:
32029900
4.

Patient perceived value of teleophthalmology in an urban, low income US population with diabetes.

Ramchandran RS, Yilmaz S, Greaux E, Dozier A.

PLoS One. 2020 Jan 9;15(1):e0225300. doi: 10.1371/journal.pone.0225300. eCollection 2020.

5.

miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer.

Parashar D, Geethadevi A, Aure MR, Mishra J, George J, Chen C, Mishra MK, Tahiri A, Zhao W, Nair B, Lu Y, Mangala LS, Rodriguez-Aguayo C, Lopez-Berestein G, Camara AKS, Liang M, Rader JS, Ramchandran R, You M, Sood AK, Kristensen VN, Mills GB, Pradeep S, Chaluvally-Raghavan P.

Cell Rep. 2019 Dec 24;29(13):4389-4406.e10. doi: 10.1016/j.celrep.2019.11.085.

6.

Discovery and Characterization of Halogenated Xanthene Inhibitors of DUSP5 as Potential Photodynamic Therapeutics.

Bongard RD, Lepley M, Gastonguay A, Syrlybaeva RR, Talipov MR, Lipinsky RAJ, Leigh NR, Brahmbhatt J, Kutty R, Rathore R, Ramchandran R, Sem DS.

J Photochem Photobiol A Chem. 2019 Apr 15;375:114-131. doi: 10.1016/j.jphotochem.2019.01.005. Epub 2019 Feb 10.

PMID:
31839699
7.

Cardiomyocyte-Specific Snrk Prevents Inflammation in the Heart.

Thirugnanam K, Cossette SM, Lu Q, Chowdhury SR, Harmann LM, Gupta A, Spearman AD, Sonin DL, Bordas M, Kumar SN, Pan AY, Simpson PM, Strande JL, Bishop E, Zou MH, Ramchandran R.

J Am Heart Assoc. 2019 Nov 19;8(22):e012792. doi: 10.1161/JAHA.119.012792. Epub 2019 Nov 13.

8.

Interaction of tumor cells and astrocytes promotes breast cancer brain metastases through TGF-β2/ANGPTL4 axes.

Gong X, Hou Z, Endsley MP, Gronseth EI, Rarick KR, Jorns JM, Yang Q, Du Z, Yan K, Bordas ML, Gershan J, Deepak P, Geethadevi A, Chaluvally-Raghavan P, Fan Y, Harder DR, Ramchandran R, Wang L.

NPJ Precis Oncol. 2019 Oct 3;3:24. doi: 10.1038/s41698-019-0094-1. eCollection 2019.

9.

Lessons learned from a lncRNA odyssey for two genes with vascular functions, DLL4 and TIE1.

Chowdhury TA, Li K, Ramchandran R.

Vascul Pharmacol. 2019 Mar;114:103-109. doi: 10.1016/j.vph.2018.06.010. Review.

10.

Role of Conserved Histidine and Serine in the HCXXXXXRS Motif of Human Dual-Specificity Phosphatase 5.

Gupta A, Brahmbhatt J, Syrlybaeva R, Bodnar C, Bodnar N, Bongard R, Pokkuluri PR, Sem DS, Ramchandran R, Rathore R, Talipov MR.

J Chem Inf Model. 2019 Apr 22;59(4):1563-1574. doi: 10.1021/acs.jcim.8b00919. Epub 2019 Mar 20.

PMID:
30835471
11.

Clinico-radiological characteristics and not laboratory markers are useful in diagnosing diabetic myonecrosis in Asian Indian patients with type 2 diabetes mellitus: A 10-year experience from South India.

Gupta RD, Haobam SS, Krishna A, Ramchandran R, Satyaraddi A, Shetty S, Asha HS, Paul TV, Thomas N.

J Family Med Prim Care. 2018 Nov-Dec;7(6):1243-1247. doi: 10.4103/jfmpc.jfmpc_4_18.

12.

Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish ( Danio rerio).

Eisa-Beygi S, Benslimane FM, El-Rass S, Prabhudesai S, Abdelrasoul MKA, Simpson PM, Yalcin HC, Burrows PE, Ramchandran R.

Arterioscler Thromb Vasc Biol. 2018 Dec;38(12):2806-2818. doi: 10.1161/ATVBAHA.118.311231.

13.

Tuberculosis infection control measures at health care facilities offering HIV and tuberculosis services in India: A baseline assessment.

Sachdeva KS, Deshmukh RD, Seguy NS, Nair SA, Rewari BB, Ramchandran R, Parmar M, Vohra V, Singh S, Ghedia M, Agarwal R, Shah AN, Balasubramanian D, Bamrotiya M, Sikhamani R, Gupta RS, Khaparde SD.

Indian J Tuberc. 2018 Oct;65(4):280-284. doi: 10.1016/j.ijtb.2018.04.004. Epub 2018 Apr 19.

PMID:
30522613
14.

Corrigendum: Cystathionine β-Synthase Is Necessary for Axis Development in vivo.

Prabhudesai S, Koceja C, Dey A, Eisa-Beygi S, Leigh NR, Bhattacharya R, Mukherjee P, Ramchandran R.

Front Cell Dev Biol. 2018 Sep 27;6:121. doi: 10.3389/fcell.2018.00121. eCollection 2018.

15.

Bitter experience with liquorice sweetening agent resulting in apparent mineralocorticoid excess with periodic paralysis.

Ramchandran R, Verma S, Dasgupta R, Thomas N.

BMJ Case Rep. 2018 Aug 10;2018. pii: bcr-2018-225686. doi: 10.1136/bcr-2018-225686.

PMID:
30097547
16.

Neurologic Complications of Acute Posterior Multifocal Placoid Pigment Epitheliopathy: A Case Series of 4 Patients.

Tsuboyama M, Chandler JV, Scharf E, Scagnelli J, Ramchandran RS, Holloway R, Wychowski T.

Neurohospitalist. 2018 Jul;8(3):146-151. doi: 10.1177/1941874417749379. Epub 2018 Jan 17.

17.

Correction to "Critical Role of the Secondary Binding Pocket in Modulating the Enzymatic Activity of DUSP5 toward Phosphorylated ERKs".

Talipov MR, Nayak J, Lepley M, Bongard RD, Sem DS, Ramchandran R, Rathore R.

Biochemistry. 2018 Jul 3;57(26):3987. doi: 10.1021/acs.biochem.8b00570. Epub 2018 Jun 13. No abstract available.

PMID:
29897735
18.

Temporal and Spatial Post-Transcriptional Regulation of Zebrafish tie1 mRNA by Long Noncoding RNA During Brain Vascular Assembly.

Chowdhury TA, Koceja C, Eisa-Beygi S, Kleinstiver BP, Kumar SN, Lin CW, Li K, Prabhudesai S, Joung JK, Ramchandran R.

Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1562-1575. doi: 10.1161/ATVBAHA.118.310848. Epub 2018 May 3.

19.

Correction: RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells (doi:10.1242/jcs.167601).

Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun C, Ramchandran R, Ekker SC, Mukhopadhyay D.

J Cell Sci. 2018 Mar 16;131(6). pii: jcs217604. doi: 10.1242/jcs.217604. No abstract available.

20.

Cystathionine β-Synthase Is Necessary for Axis Development in Vivo.

Prabhudesai S, Koceja C, Dey A, Eisa-Beygi S, Leigh NR, Bhattacharya R, Mukherjee P, Ramchandran R.

Front Cell Dev Biol. 2018 Feb 16;6:14. doi: 10.3389/fcell.2018.00014. eCollection 2018. Erratum in: Front Cell Dev Biol. 2018 Sep 27;6:121.

21.

SNRK (Sucrose Nonfermenting 1-Related Kinase) Promotes Angiogenesis In Vivo.

Lu Q, Xie Z, Yan C, Ding Y, Ma Z, Wu S, Qiu Y, Cossette SM, Bordas M, Ramchandran R, Zou MH.

Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):373-385. doi: 10.1161/ATVBAHA.117.309834. Epub 2017 Dec 14. Erratum in: Arterioscler Thromb Vasc Biol. 2019 Sep;39(9):e209.

22.

Current Shortcomings of Camera Screening.

Ramchandran RS, Feldon SE, Owsley C.

JAMA Intern Med. 2017 Oct 1;177(10):1539. doi: 10.1001/jamainternmed.2017.3833. No abstract available.

PMID:
28973273
23.

Dual Specificity Phosphatase 5-Substrate Interaction: A Mechanistic Perspective.

Kutty RG, Talipov MR, Bongard RD, Lipinski RAJ, Sweeney NL, Sem DS, Rathore R, Ramchandran R.

Compr Physiol. 2017 Sep 12;7(4):1449-1461. doi: 10.1002/cphy.c170007. Review.

PMID:
28915331
24.

Sucrose Non-Fermenting Related Kinase Expression in Ovarian Cancer and Correlation with Clinical Features.

Hopp EE, Cossette SM, Kumar SN, Eastwood D, Ramchandran R, Bishop E.

Cancer Invest. 2017 Aug 9;35(7):456-462. doi: 10.1080/07357907.2017.1337781. Epub 2017 Jul 19.

25.

miRNA-Mediated RNA Activation in Mammalian Cells.

Ramchandran R, Chaluvally-Raghavan P.

Adv Exp Med Biol. 2017;983:81-89. doi: 10.1007/978-981-10-4310-9_6.

PMID:
28639193
26.

Serendipitous discovery of light-induced (In Situ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor.

Bongard RD, Lepley M, Thakur K, Talipov MR, Nayak J, Lipinski RAJ, Bohl C, Sweeney N, Ramchandran R, Rathore R, Sem DS.

BMC Biochem. 2017 May 31;18(1):10. doi: 10.1186/s12858-017-0083-3.

27.

Dual Specificity Phosphatase 5 Is Essential for T Cell Survival.

Kutty RG, Xin G, Schauder DM, Cossette SM, Bordas M, Cui W, Ramchandran R.

PLoS One. 2016 Dec 9;11(12):e0167246. doi: 10.1371/journal.pone.0167246. eCollection 2016.

28.

Sucrose Nonfermenting-Related Kinase Enzyme-Mediated Rho-Associated Kinase Signaling is Responsible for Cardiac Function.

Cossette SM, Bhute VJ, Bao X, Harmann LM, Horswill MA, Sinha I, Gastonguay A, Pooya S, Bordas M, Kumar SN, Mirza SP, Palecek SP, Strande JL, Ramchandran R.

Circ Cardiovasc Genet. 2016 Dec;9(6):474-486. doi: 10.1161/CIRCGENETICS.116.001515. Epub 2016 Oct 25.

29.

Critical Role of the Secondary Binding Pocket in Modulating the Enzymatic Activity of DUSP5 toward Phosphorylated ERKs.

Talipov MR, Nayak J, Lepley M, Bongard RD, Sem DS, Ramchandran R, Rathore R.

Biochemistry. 2016 Nov 8;55(44):6187-6195. Epub 2016 Oct 26. Erratum in: Biochemistry. 2018 Jul 3;57(26):3987.

PMID:
27739308
30.

Smooth Muscle Insulin-Like Growth Factor-1 Mediates Hypoxia-Induced Pulmonary Hypertension in Neonatal Mice.

Sun M, Ramchandran R, Chen J, Yang Q, Raj JU.

Am J Respir Cell Mol Biol. 2016 Dec;55(6):779-791.

31.

E-cadherin re-expression shows in vivo evidence for mesenchymal to epithelial transition in clonal metastatic breast tumor cells.

Palen K, Weber J, Dwinell MB, Johnson BD, Ramchandran R, Gershan JA.

Oncotarget. 2016 Jul 12;7(28):43363-43375. doi: 10.18632/oncotarget.9715.

32.

The lncRNA PVT1 Contributes to the Cervical Cancer Phenotype and Associates with Poor Patient Prognosis.

Iden M, Fye S, Li K, Chowdhury T, Ramchandran R, Rader JS.

PLoS One. 2016 May 27;11(5):e0156274. doi: 10.1371/journal.pone.0156274. eCollection 2016.

33.

MicroRNA-223 Attenuates Hypoxia-induced Vascular Remodeling by Targeting RhoB/MLC2 in Pulmonary Arterial Smooth Muscle Cells.

Zeng Y, Zhang X, Kang K, Chen J, Wu Z, Huang J, Lu W, Chen Y, Zhang J, Wang Z, Zhai Y, Qu J, Ramchandran R, Raj JU, Wang J, Gou D.

Sci Rep. 2016 Apr 28;6:24900. doi: 10.1038/srep24900.

34.

Nogo-B receptor deficiency causes cerebral vasculature defects during embryonic development in mice.

Rana U, Liu Z, Kumar SN, Zhao B, Hu W, Bordas M, Cossette S, Szabo S, Foeckler J, Weiler H, Chrzanowska-Wodnicka M, Holtz ML, Misra RP, Salato V, North PE, Ramchandran R, Miao QR.

Dev Biol. 2016 Feb 15;410(2):190-201. doi: 10.1016/j.ydbio.2015.12.023. Epub 2015 Dec 31.

35.

Endothelial Cell Surface Expressed Chemotaxis and Apoptosis Regulator (ECSCR) Regulates Lipolysis in White Adipocytes via the PTEN/AKT Signaling Pathway.

Kilari S, Cossette S, Pooya S, Bordas M, Huang YW, Ramchandran R, Wilkinson GA.

PLoS One. 2015 Dec 21;10(12):e0144185. doi: 10.1371/journal.pone.0144185. eCollection 2015.

36.

Cystathionine β-synthase regulates endothelial function via protein S-sulfhydration.

Saha S, Chakraborty PK, Xiong X, Dwivedi SK, Mustafi SB, Leigh NR, Ramchandran R, Mukherjee P, Bhattacharya R.

FASEB J. 2016 Jan;30(1):441-56. doi: 10.1096/fj.15-278648. Epub 2015 Sep 24.

37.

Correction: Astrocytes Directly Influence Tumor Cell Invasion and Metastasis In Vivo.

Wang L, Cossette SM, Rarick KR, Gershan J, Dwinell MB, Harder DR, Ramchandran R.

PLoS One. 2015 Aug 31;10(8):e0137369. doi: 10.1371/journal.pone.0137369. eCollection 2015. No abstract available.

38.

Identification of inhibitors that target dual-specificity phosphatase 5 provide new insights into the binding requirements for the two phosphate pockets.

Neumann TS, Span EA, Kalous KS, Bongard R, Gastonguay A, Lepley MA, Kutty RG, Nayak J, Bohl C, Lange RG, Sarker MI, Talipov MR, Rathore R, Ramchandran R, Sem DS.

BMC Biochem. 2015 Aug 19;16:19. doi: 10.1186/s12858-015-0048-3.

39.

Evaluation of Cataract Surgery Outcomes at the Ban Phaeo Mobile Eye Clinic, Thailand.

Thavikulwat AT, Fisher SG, Thevenet-Morrison K, Pongtawigorn P, Ramchandran RS.

Ophthalmic Epidemiol. 2015;22(4):266-73. doi: 10.3109/09286586.2015.1009120.

PMID:
26218109
40.

Gene Expression in Experimental Aortic Coarctation and Repair: Candidate Genes for Therapeutic Intervention?

LaDisa JF Jr, Bozdag S, Olson J, Ramchandran R, Kersten JR, Eddinger TJ.

PLoS One. 2015 Jul 24;10(7):e0133356. doi: 10.1371/journal.pone.0133356. eCollection 2015.

41.

Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells.

Zeng Y, Liu H, Kang K, Wang Z, Hui G, Zhang X, Zhong J, Peng W, Ramchandran R, Raj JU, Gou D.

Sci Rep. 2015 Jul 13;5:12098. doi: 10.1038/srep12098.

42.

RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells.

Hoeppner LH, Sinha S, Wang Y, Bhattacharya R, Dutta S, Gong X, Bedell VM, Suresh S, Chun C, Ramchandran R, Ekker SC, Mukhopadhyay D.

J Cell Sci. 2015 Oct 1;128(19):3556-68. doi: 10.1242/jcs.167601. Epub 2015 Jul 1. Erratum in: J Cell Sci. 2018 Mar 16;131(6):.

43.

SIGIRR genetic variants in premature infants with necrotizing enterocolitis.

Sampath V, Menden H, Helbling D, Li K, Gastonguay A, Ramchandran R, Dimmock DP.

Pediatrics. 2015 Jun;135(6):e1530-4. doi: 10.1542/peds.2014-3386. Epub 2015 May 11.

44.

IGF-1 signaling in neonatal hypoxia-induced pulmonary hypertension: Role of epigenetic regulation.

Yang Q, Sun M, Ramchandran R, Raj JU.

Vascul Pharmacol. 2015 Oct;73:20-31. doi: 10.1016/j.vph.2015.04.005. Epub 2015 Apr 25.

45.

Delta-like 4 mRNA is regulated by adjacent natural antisense transcripts.

Li K, Chowdhury T, Vakeel P, Koceja C, Sampath V, Ramchandran R.

Vasc Cell. 2015 Mar 24;7:3. doi: 10.1186/s13221-015-0028-9. eCollection 2015.

46.

Organization for rare diseases India (ORDI) - addressing the challenges and opportunities for the Indian rare diseases' community.

Rajasimha HK, Shirol PB, Ramamoorthy P, Hegde M, Barde S, Chandru V, Ravinandan ME, Ramchandran R, Haldar K, Lin JC, Babar IA, Girisha KM, Srinivasan S, Navaneetham D, Battu R, Devarakonda R, Kini U, Vijayachandra K, Verma IC.

Genet Res (Camb). 2014 Aug 13;96:e009. doi: 10.1017/S0016672314000111. Review.

47.

Lipopolysaccharide (LPS)-mediated angiopoietin-2-dependent autocrine angiogenesis is regulated by NADPH oxidase 2 (Nox2) in human pulmonary microvascular endothelial cells.

Menden H, Welak S, Cossette S, Ramchandran R, Sampath V.

J Biol Chem. 2015 Feb 27;290(9):5449-61. doi: 10.1074/jbc.M114.600692. Epub 2015 Jan 7.

48.

Protein expression, characterization and activity comparisons of wild type and mutant DUSP5 proteins.

Nayak J, Gastonguay AJ, Talipov MR, Vakeel P, Span EA, Kalous KS, Kutty RG, Jensen DR, Pokkuluri PR, Sem DS, Rathore R, Ramchandran R.

BMC Biochem. 2014 Dec 18;15:27. doi: 10.1186/s12858-014-0027-0.

49.

Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism.

Cossette SM, Gastonguay AJ, Bao X, Lerch-Gaggl A, Zhong L, Harmann LM, Koceja C, Miao RQ, Vakeel P, Chun C, Li K, Foeckler J, Bordas M, Weiler H, Strande J, Palecek SP, Ramchandran R.

Biol Open. 2014 Dec 12;4(1):48-61. doi: 10.1242/bio.20149811.

50.

MiR-20a regulates the PRKG1 gene by targeting its coding region in pulmonary arterial smooth muscle cells.

Zeng Y, Pan Y, Liu H, Kang K, Wu Y, Hui G, Peng W, Ramchandran R, Raj JU, Gou D.

FEBS Lett. 2014 Dec 20;588(24):4677-85. doi: 10.1016/j.febslet.2014.10.040. Epub 2014 Nov 13.

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