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Items: 1 to 50 of 59

1.

Preclinical Pharmacokinetics of Fosciclopirox, a Novel Treatment of Urothelial Cancers, in Rats and Dogs.

Weir SJ, Wood R, Schorno K, Brinker AE, Ramamoorthy P, Heppert K, Rajewski L, Tanol M, Ham T, McKenna MJ, McCulloch W, Dalton M, Reed GA, Jensen RA, Baltezor MJ, Anant S, Taylor JA 3rd.

J Pharmacol Exp Ther. 2019 Aug;370(2):148-159. doi: 10.1124/jpet.119.257972. Epub 2019 May 21.

PMID:
31113837
2.

Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and progression.

Roy BC, Ahmed I, Ramalingam S, Jala V, Haribabu B, Ramamoorthy P, Ashcraft J, Valentino J, Anant S, Sampath V, Umar S.

Oncotarget. 2019 Mar 22;10(24):2340-2354. doi: 10.18632/oncotarget.26684. eCollection 2019 Mar 22.

3.

Pleotropic role of RNA binding protein CELF2 in autophagy induction.

New J, Subramaniam D, Ramalingam S, Enders J, Sayed AAA, Ponnurangam S, Standing D, Ramamoorthy P, O'Neil M, Dixon DA, Saha S, Umar S, Gunewardena S, Jensen RA, Thomas SM, Anant S.

Mol Carcinog. 2019 Aug;58(8):1400-1409. doi: 10.1002/mc.23023. Epub 2019 Apr 24.

PMID:
31020708
4.

Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response.

Ramamoorthy P, Thomas SM, Kaushik G, Subramaniam D, Chastain KM, Dhar A, Tawfik O, Kasi A, Sun W, Ramalingam S, Gunewardena S, Umar S, Mammen JM, Padhye SB, Weir SJ, Jensen RA, Sittampalam GS, Anant S.

Cancer Res. 2019 Apr 1;79(7):1681-1695. doi: 10.1158/0008-5472.CAN-18-2602. Epub 2019 Jan 23.

PMID:
30674533
5.

Expression of Hypoxia Inducible Factor 1alpha Is Protein Kinase A-dependent in Primary Cortical Astrocytes Exposed to Severe Hypoxia.

Ramamoorthy P, Xu G, Shi H.

Neurochem Res. 2019 Jan;44(1):258-268. doi: 10.1007/s11064-018-2516-9. Epub 2018 Mar 27.

PMID:
29589179
6.

StrandAdvantage test for early-line and advanced-stage treatment decisions in solid tumors.

Sen M, Katragadda S, Ravichandran A, Deshpande G, Parulekar M, Nayanala S, Vittal V, Shen W, Phooi Nee Yong M, Jacob J, Parchuru S, Dhanuskodi K, Eyring K, Agrawal P, Agarwal S, Shanmugam A, Gupta S, Vishwanath D, Kumari K, Hariharan AK, Balaji SA, Liang Q, Robolledo B, Gauribidanur Raghavendrachar V, Oomer Farooque M, Buresh CJ, Ramamoorthy P, Bahadur U, Subramanian K, Hariharan R, Veeramachaneni V, Sankaran S, Gupta V.

Cancer Med. 2017 May;6(5):883-901. doi: 10.1002/cam4.1037. Epub 2017 Apr 3.

7.

Root traits confer grain yield advantages under terminal drought in chickpea (Cicer arietinum L.).

Ramamoorthy P, Lakshmanan K, Upadhyaya HD, Vadez V, Varshney RK.

Field Crops Res. 2017 Feb 1;201:146-161. doi: 10.1016/j.fcr.2016.11.004.

8.

Shoot traits and their relevance in terminal drought tolerance of chickpea (Cicer arietinum L.).

Ramamoorthy P, Lakshmanan K, Upadhyaya HD, Vadez V, Varshney RK.

Field Crops Res. 2016 Oct;197:10-27.

9.

Detection of high frequency of mutations in a breast and/or ovarian cancer cohort: implications of embracing a multi-gene panel in molecular diagnosis in India.

Mannan AU, Singh J, Lakshmikeshava R, Thota N, Singh S, Sowmya TS, Mishra A, Sinha A, Deshwal S, Soni MR, Chandrasekar A, Ramesh B, Ramamurthy B, Padhi S, Manek P, Ramalingam R, Kapoor S, Ghosh M, Sankaran S, Ghosh A, Veeramachaneni V, Ramamoorthy P, Hariharan R, Subramanian K.

J Hum Genet. 2016 Jun;61(6):515-22. doi: 10.1038/jhg.2016.4. Epub 2016 Feb 25.

PMID:
26911350
10.

The Effect of Viral Infection on Exhaled Nitric Oxide in Children with Acute Asthma Exacerbations.

Malka J, Covar R, Faino A, Fish J, Pickering P, Ramamoorthy P, Gleason M, Spahn JD.

J Allergy Clin Immunol Pract. 2015 Nov-Dec;3(6):913-9. doi: 10.1016/j.jaip.2015.05.029. Epub 2015 Jul 26.

PMID:
26216254
11.

Organization for rare diseases India (ORDI) - addressing the challenges and opportunities for the Indian rare diseases' community.

Rajasimha HK, Shirol PB, Ramamoorthy P, Hegde M, Barde S, Chandru V, Ravinandan ME, Ramchandran R, Haldar K, Lin JC, Babar IA, Girisha KM, Srinivasan S, Navaneetham D, Battu R, Devarakonda R, Kini U, Vijayachandra K, Verma IC.

Genet Res (Camb). 2014 Aug 13;96:e009. doi: 10.1017/S0016672314000111. Review.

PMID:
25579084
12.

Honokiol inhibits melanoma stem cells by targeting notch signaling.

Kaushik G, Venugopal A, Ramamoorthy P, Standing D, Subramaniam D, Umar S, Jensen RA, Anant S, Mammen JM.

Mol Carcinog. 2015 Dec;54(12):1710-21. doi: 10.1002/mc.22242. Epub 2014 Dec 9.

13.

Genome sequencing of Mycobacterium abscessus isolates from patients in the united states and comparisons to globally diverse clinical strains.

Davidson RM, Hasan NA, Reynolds PR, Totten S, Garcia B, Levin A, Ramamoorthy P, Heifets L, Daley CL, Strong M.

J Clin Microbiol. 2014 Oct;52(10):3573-82. doi: 10.1128/JCM.01144-14. Epub 2014 Jul 23.

14.

Ischemia induces different levels of hypoxia inducible factor-1α protein expression in interneurons and pyramidal neurons.

Ramamoorthy P, Shi H.

Acta Neuropathol Commun. 2014 May 5;2:51. doi: 10.1186/2051-5960-2-51.

15.

Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy.

Kim J, Vasu VT, Mishra R, Singleton KR, Yoo M, Leach SM, Farias-Hesson E, Mason RJ, Kang J, Ramamoorthy P, Kern JA, Heasley LE, Finigan JH, Tan AC.

Bioinformatics. 2014 Sep 1;30(17):2393-8. doi: 10.1093/bioinformatics/btu323. Epub 2014 May 7.

16.

Increased compound heterozygous filaggrin mutations in severe atopic dermatitis in the United States.

Mohiuddin MS, Ramamoorthy P, Reynolds PR, Curran-Everett D, Leung DY.

J Allergy Clin Immunol Pract. 2013 Sep-Oct;1(5):534-6. doi: 10.1016/j.jaip.2013.06.006. Epub 2013 Jul 30. No abstract available.

PMID:
24565632
17.

Toward more transparent and reproducible omics studies through a common metadata checklist and data publications.

Kolker E, Özdemir V, Martens L, Hancock W, Anderson G, Anderson N, Aynacioglu S, Baranova A, Campagna SR, Chen R, Choiniere J, Dearth SP, Feng WC, Ferguson L, Fox G, Frishman D, Grossman R, Heath A, Higdon R, Hutz MH, Janko I, Jiang L, Joshi S, Kel A, Kemnitz JW, Kohane IS, Kolker N, Lancet D, Lee E, Li W, Lisitsa A, Llerena A, Macnealy-Koch C, Marshall JC, Masuzzo P, May A, Mias G, Monroe M, Montague E, Mooney S, Nesvizhskii A, Noronha S, Omenn G, Rajasimha H, Ramamoorthy P, Sheehan J, Smarr L, Smith CV, Smith T, Snyder M, Rapole S, Srivastava S, Stanberry L, Stewart E, Toppo S, Uetz P, Verheggen K, Voy BH, Warnich L, Wilhelm SW, Yandl G.

OMICS. 2014 Jan;18(1):10-4. doi: 10.1089/omi.2013.0149.

18.

Compliance factors associated with contact lens-related dry eye.

Ramamoorthy P, Nichols JJ.

Eye Contact Lens. 2014 Jan;40(1):17-22. doi: 10.1097/ICL.0000000000000009.

PMID:
24335450
19.

Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications.

Kolker E, Özdemir V, Martens L, Hancock W, Anderson G, Anderson N, Aynacioglu S, Baranova A, Campagna SR, Chen R, Choiniere J, Dearth SP, Feng WC, Ferguson L, Fox G, Frishman D, Grossman R, Heath A, Higdon R, Hutz MH, Janko I, Jiang L, Joshi S, Kel A, Kemnitz JW, Kohane IS, Kolker N, Lancet D, Lee E, Li W, Lisitsa A, Llerena A, MacNealy-Koch C, Marshall JC, Masuzzo P, May A, Mias G, Monroe M, Montague E, Mooney S, Nesvizhskii A, Noronha S, Omenn G, Rajasimha H, Ramamoorthy P, Sheehan J, Smarr L, Smith CV, Smith T, Snyder M, Rapole S, Srivastava S, Stanberry L, Stewart E, Toppo S, Uetz P, Verheggen K, Voy BH, Warnich L, Wilhelm SW, Yandl G.

Big Data. 2013 Dec;1(4):196-201. doi: 10.1089/big.2013.0039.

PMID:
27447251
20.

Tear film images and breakup analyzed using fluorescent quenching.

King-Smith PE, Ramamoorthy P, Braun RJ, Nichols JJ.

Invest Ophthalmol Vis Sci. 2013 Sep 5;54(9):6003-11. doi: 10.1167/iovs.13-12628.

21.

Utility of a bacterial infection model to study epithelial-mesenchymal transition, mesenchymal-epithelial transition or tumorigenesis.

Chandrakesan P, Roy B, Jakkula LU, Ahmed I, Ramamoorthy P, Tawfik O, Papineni R, Houchen C, Anant S, Umar S.

Oncogene. 2014 May 15;33(20):2639-54. doi: 10.1038/onc.2013.210. Epub 2013 Jun 10.

22.

IL-25 enhances HSV-1 replication by inhibiting filaggrin expression, and acts synergistically with Th2 cytokines to enhance HSV-1 replication.

Kim BE, Bin L, Ye YM, Ramamoorthy P, Leung DYM.

J Invest Dermatol. 2013 Dec;133(12):2678-2685. doi: 10.1038/jid.2013.223. Epub 2013 May 8.

23.

Hypoxia alters ocular drug transporter expression and activity in rat and calf models: implications for drug delivery.

Kadam RS, Ramamoorthy P, LaFlamme DJ, McKinsey TA, Kompella UB.

Mol Pharm. 2013 Jun 3;10(6):2350-61. doi: 10.1021/mp3007133. Epub 2013 May 22. Retraction in: Mol Pharm. 2015 Jul 6;12(7):2559.

24.

Methanolic extracts of bitter melon inhibit colon cancer stem cells by affecting energy homeostasis and autophagy.

Kwatra D, Subramaniam D, Ramamoorthy P, Standing D, Moran E, Velayutham R, Mitra A, Umar S, Anant S.

Evid Based Complement Alternat Med. 2013;2013:702869. doi: 10.1155/2013/702869. Epub 2013 Mar 6.

25.

Patients with nontuberculous mycobacterial lung disease exhibit unique body and immune phenotypes.

Kartalija M, Ovrutsky AR, Bryan CL, Pott GB, Fantuzzi G, Thomas J, Strand MJ, Bai X, Ramamoorthy P, Rothman MS, Nagabhushanam V, McDermott M, Levin AR, Frazer-Abel A, Giclas PC, Korner J, Iseman MD, Shapiro L, Chan ED.

Am J Respir Crit Care Med. 2013 Jan 15;187(2):197-205. doi: 10.1164/rccm.201206-1035OC. Epub 2012 Nov 9.

26.

Hypoxia-inducible factor 1 protects hypoxic astrocytes against glutamate toxicity.

Badawi Y, Ramamoorthy P, Shi H.

ASN Neuro. 2012 May 30;4(4):231-41. doi: 10.1042/AN20120006.

27.

Curcumin induces cell death in esophageal cancer cells through modulating Notch signaling.

Subramaniam D, Ponnurangam S, Ramamoorthy P, Standing D, Battafarano RJ, Anant S, Sharma P.

PLoS One. 2012;7(2):e30590. doi: 10.1371/journal.pone.0030590. Epub 2012 Feb 17.

28.

Development of the 4-3-2-1 meibum expressibility scale.

Meadows JF, Ramamoorthy P, Nichols JJ, Nichols KK.

Eye Contact Lens. 2012 Mar;38(2):86-92. doi: 10.1097/ICL.0b013e318242b494.

PMID:
22249431
29.

Reduced Expression of RNA Binding Protein CELF2, a Putative Tumor Suppressor Gene in Colon Cancer.

Ramalingam S, Ramamoorthy P, Subramaniam D, Anant S.

Immunogastroenterology. 2012;1(1):27-33.

30.

Activation of NPY type 5 receptors induces a long-lasting increase in spontaneous GABA release from cerebellar inhibitory interneurons.

Dubois CJ, Ramamoorthy P, Whim MD, Liu SJ.

J Neurophysiol. 2012 Mar;107(6):1655-65. doi: 10.1152/jn.00755.2011. Epub 2011 Dec 21.

31.

Efficacy of occupant-collected dust samples in the evaluation of residential allergen and fungal levels.

Van Dyke MV, Martyny JW, Marola J, Ramamoorthy P, Ridder A, Harbeck RJ, Rose CS.

J Occup Environ Hyg. 2012;9(1):14-24. doi: 10.1080/15459624.2012.633069.

PMID:
22150472
32.

Cell type-dependent trafficking of neuropeptide Y-containing dense core granules in CNS neurons.

Ramamoorthy P, Wang Q, Whim MD.

J Neurosci. 2011 Oct 12;31(41):14783-8. doi: 10.1523/JNEUROSCI.2933-11.2011.

33.

Achieving better healthcare through diverse leadership. Interview by Mari Paul.

Ramamoorthy P.

Nat Biotechnol. 2011 Jul 11;29(7):665-6. doi: 10.1038/nbt.1916. No abstract available.

PMID:
21747389
34.

Validation of the Cepheid Xpert Flu A real time RT-PCR detection panel for emergency use authorization.

Sambol AR, Iwen PC, Pieretti M, Basu S, Levi MH, Gilonske KD, Moses KD, Marola JL, Ramamoorthy P.

J Clin Virol. 2010 Aug;48(4):234-8. doi: 10.1016/j.jcv.2010.06.001. Epub 2010 Jun 26.

PMID:
20580600
35.

Contact lens material characteristics associated with hydrogel lens dehydration.

Ramamoorthy P, Sinnott LT, Nichols JJ.

Ophthalmic Physiol Opt. 2010 Mar;30(2):160-6. doi: 10.1111/j.1475-1313.2009.00705.x.

PMID:
20444120
36.

Differential changes of glutathione levels in astrocytes and neurons in ischemic brains by two-photon imaging.

Bragin DE, Zhou B, Ramamoorthy P, Müller WS, Connor JA, Shi H.

J Cereb Blood Flow Metab. 2010 Apr;30(4):734-8. doi: 10.1038/jcbfm.2010.9. Epub 2010 Jan 27.

37.

A common single nucleotide polymorphism alters the synthesis and secretion of neuropeptide Y.

Mitchell GC, Wang Q, Ramamoorthy P, Whim MD.

J Neurosci. 2008 Dec 31;28(53):14428-34. doi: 10.1523/JNEUROSCI.0343-08.2008.

38.

Trafficking and fusion of neuropeptide Y-containing dense-core granules in astrocytes.

Ramamoorthy P, Whim MD.

J Neurosci. 2008 Dec 17;28(51):13815-27. doi: 10.1523/JNEUROSCI.5361-07.2008.

39.

Treatment, material, care, and patient-related factors in contact lens-related dry eye.

Ramamoorthy P, Sinnott LT, Nichols JJ.

Optom Vis Sci. 2008 Aug;85(8):764-72. doi: 10.1097/OPX.0b013e318181a91f.

40.

Mucins in contact lens wear and dry eye conditions.

Ramamoorthy P, Nichols JJ.

Optom Vis Sci. 2008 Aug;85(8):631-42. doi: 10.1097/OPX.0b013e3181819f25. Review.

PMID:
18677222
41.

Early indicators of exposure to biological threat agents using host gene profiles in peripheral blood mononuclear cells.

Das R, Hammamieh R, Neill R, Ludwig GV, Eker S, Lincoln P, Ramamoorthy P, Dhokalia A, Mani S, Mendis C, Cummings C, Kearney B, Royaee A, Huang XZ, Paranavitana C, Smith L, Peel S, Kanesa-Thasan N, Hoover D, Lindler LE, Yang D, Henchal E, Jett M.

BMC Infect Dis. 2008 Jul 30;8:104. doi: 10.1186/1471-2334-8-104.

42.

Renal damage in experimentally-induced cirrhosis in rats: Role of oxygen free radicals.

Natarajan SK, Basivireddy J, Ramachandran A, Thomas S, Ramamoorthy P, Pulimood AB, Jacob M, Balasubramanian KA.

Hepatology. 2006 Jun;43(6):1248-56.

PMID:
16729302
43.

Oxidative stress in the development of liver cirrhosis: a comparison of two different experimental models.

Natarajan SK, Thomas S, Ramamoorthy P, Basivireddy J, Pulimood AB, Ramachandran A, Balasubramanian KA.

J Gastroenterol Hepatol. 2006 Jun;21(6):947-57.

PMID:
16724977
44.

Mild whole-body heat stress alters retinoid metabolism in the rat small intestine.

Ramamoorthy P, Thomas S, Ramachandran A, Balasubramanian KA.

Dig Dis Sci. 2006 Mar;51(3):466-70.

PMID:
16614953
45.

Intestinal mucosal alterations in rats with carbon tetrachloride-induced cirrhosis: changes in glycosylation and luminal bacteria.

Natarajan SK, Ramamoorthy P, Thomas S, Basivireddy J, Kang G, Ramachandran A, Pulimood AB, Balasubramanian KA.

Hepatology. 2006 Apr;43(4):837-46.

PMID:
16557555
46.

Alterations in the intestinal glycocalyx and bacterial flora in response to oral indomethacin.

Basivireddy J, Jacob M, Ramamoorthy P, Balasubramanian KA.

Int J Biochem Cell Biol. 2005 Nov;37(11):2321-32.

PMID:
15979923
47.

Indomethacin-induced free radical-mediated changes in the intestinal brush border membranes.

Basivireddy J, Jacob M, Ramamoorthy P, Pulimood AB, Balasubramanian KA.

Biochem Pharmacol. 2003 Feb 15;65(4):683-95.

PMID:
12566098
48.

In vitro studies of a prolactin antagonist, hPRL-G129R in human breast cancer cells.

Ramamoorthy P, Sticca R, Wagner TE, Chen WY.

Int J Oncol. 2001 Jan;18(1):25-32.

PMID:
11115535
49.

Inhibition of oncogene STAT3 phosphorylation by a prolactin antagonist, hPRL-G129R, in T-47D human breast cancer cells.

Cataldo L, Chen NY, Yuan Q, Li W, Ramamoorthy P, Wagner TE, Sticca RP, Chen WY.

Int J Oncol. 2000 Dec;17(6):1179-85.

PMID:
11078803
50.

A human prolactin antagonist, hPRL-G129R, inhibits breast cancer cell proliferation through induction of apoptosis.

Chen WY, Ramamoorthy P, Chen N, Sticca R, Wagner TE.

Clin Cancer Res. 1999 Nov;5(11):3583-93. Erratum in: Clin Cancer Res 2000 May;6(5):2120.

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