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Items: 1 to 50 of 325

1.

Excitation of Diverse Classes of Cholecystokinin Interneurons in the Basal Amygdala Facilitates Fear Extinction.

Rovira-Esteban L, Gunduz-Cinar O, Bukalo O, Limoges A, Brockway E, Müller K, Fenno L, Kim YS, Ramakrishnan C, Andrási T, Deisseroth K, Holmes A, Hájos N.

eNeuro. 2019 Nov 7;6(6). pii: ENEURO.0220-19.2019. doi: 10.1523/ENEURO.0220-19.2019. Print 2019 Nov/Dec.

2.

Stereochemical Assessment of (φ,ψ) Outliers in Protein Structures Using Bond Geometry-Specific Ramachandran Steric-Maps.

Ravikumar A, Ramakrishnan C, Srinivasan N.

Structure. 2019 Oct 9. pii: S0969-2126(19)30315-6. doi: 10.1016/j.str.2019.09.009. [Epub ahead of print]

PMID:
31607615
3.

Mapping Brain-Wide Afferent Inputs of Parvalbumin-Expressing GABAergic Neurons in Barrel Cortex Reveals Local and Long-Range Circuit Motifs.

Hafner G, Witte M, Guy J, Subhashini N, Fenno LE, Ramakrishnan C, Kim YS, Deisseroth K, Callaway EM, Oberhuber M, Conzelmann KK, Staiger JF.

Cell Rep. 2019 Sep 24;28(13):3450-3461.e8. doi: 10.1016/j.celrep.2019.08.064.

4.

A neuronal circuit for activating descending modulation of neuropathic pain.

Huang J, Gadotti VM, Chen L, Souza IA, Huang S, Wang D, Ramakrishnan C, Deisseroth K, Zhang Z, Zamponi GW.

Nat Neurosci. 2019 Oct;22(10):1659-1668. doi: 10.1038/s41593-019-0481-5. Epub 2019 Sep 9.

PMID:
31501573
5.

Cortical layer-specific critical dynamics triggering perception.

Marshel JH, Kim YS, Machado TA, Quirin S, Benson B, Kadmon J, Raja C, Chibukhchyan A, Ramakrishnan C, Inoue M, Shane JC, McKnight DJ, Yoshizawa S, Kato HE, Ganguli S, Deisseroth K.

Science. 2019 Aug 9;365(6453). pii: eaaw5202. doi: 10.1126/science.aaw5202. Epub 2019 Jul 18.

6.

Adiposity measures and pre-diabetes or diabetes in adults with hypertension in Singapore polyclinics.

Wang Y, Shirore RM, Ramakrishnan C, Tan NC, Jafar TH.

J Clin Hypertens (Greenwich). 2019 Jul;21(7):953-962. doi: 10.1111/jch.13587. Epub 2019 Jun 21.

7.

Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics.

Inoue M, Takeuchi A, Manita S, Horigane SI, Sakamoto M, Kawakami R, Yamaguchi K, Otomo K, Yokoyama H, Kim R, Yokoyama T, Takemoto-Kimura S, Abe M, Okamura M, Kondo Y, Quirin S, Ramakrishnan C, Imamura T, Sakimura K, Nemoto T, Kano M, Fujii H, Deisseroth K, Kitamura K, Bito H.

Cell. 2019 May 16;177(5):1346-1360.e24. doi: 10.1016/j.cell.2019.04.007. Epub 2019 May 9.

PMID:
31080068
8.

Plant latex thrombin-like cysteine proteases alleviates bleeding by bypassing factor VIII in murine model.

Urs AP, Rudresha GV, Manjuprasanna VN, Suvilesh KN, Gowda MDM, Yariswamy M, Hiremath V, Ramakrishnan C, Savitha MN, Jayachandra K, Sharanappa P, Vishwanath BS.

J Cell Biochem. 2019 Aug;120(8):12843-12858. doi: 10.1002/jcb.28555. Epub 2019 Mar 12.

PMID:
30861186
9.

Investigating the feasibility of channelrhodopsin variants for nanoscale optogenetics.

Stahlberg MA, Ramakrishnan C, Willig KI, Boyden ES, Deisseroth K, Dean C.

Neurophotonics. 2019 Jan;6(1):015007. doi: 10.1117/1.NPh.6.1.015007. Epub 2019 Feb 28.

10.

Identification of novel NAD(P)H dehydrogenase [quinone] 1 antagonist using computational approaches.

Selvakumar R, Anantha Krishnan D, Ramakrishnan C, Velmurugan D, Gunasekaran K.

J Biomol Struct Dyn. 2019 Feb 26:1-15. doi: 10.1080/07391102.2019.1585291. [Epub ahead of print]

PMID:
30806580
11.

A hypothalamus-habenula circuit controls aversion.

Lazaridis I, Tzortzi O, Weglage M, Märtin A, Xuan Y, Parent M, Johansson Y, Fuzik J, Fürth D, Fenno LE, Ramakrishnan C, Silberberg G, Deisseroth K, Carlén M, Meletis K.

Mol Psychiatry. 2019 Sep;24(9):1351-1368. doi: 10.1038/s41380-019-0369-5. Epub 2019 Feb 12.

12.

An experimental genetically attenuated live vaccine to prevent transmission of Toxoplasma gondii by cats.

Ramakrishnan C, Maier S, Walker RA, Rehrauer H, Joekel DE, Winiger RR, Basso WU, Grigg ME, Hehl AB, Deplazes P, Smith NC.

Sci Rep. 2019 Feb 6;9(1):1474. doi: 10.1038/s41598-018-37671-8.

13.

Molecular dynamics simulation studies on influenza A virus H5N1 complexed with sialic acid and fluorinated sialic acid.

Jeyaram RA, Priyadarzini TRK, Anu Radha C, Siva Shanmugam NR, Ramakrishnan C, Gromiha MM, Veluraja K.

J Biomol Struct Dyn. 2019 Nov;37(18):4813-4824. doi: 10.1080/07391102.2019.1568304. Epub 2019 Feb 22.

PMID:
30686127
14.

Interacting neural ensembles in orbitofrontal cortex for social and feeding behaviour.

Jennings JH, Kim CK, Marshel JH, Raffiee M, Ye L, Quirin S, Pak S, Ramakrishnan C, Deisseroth K.

Nature. 2019 Jan;565(7741):645-649. doi: 10.1038/s41586-018-0866-8. Epub 2019 Jan 16.

15.

Scale-Invariant Visual Capabilities Explained by Topographic Representations of Luminance and Texture in Primate V1.

Benvenuti G, Chen Y, Ramakrishnan C, Deisseroth K, Geisler WS, Seidemann E.

Neuron. 2018 Dec 19;100(6):1533. doi: 10.1016/j.neuron.2018.12.011. No abstract available.

16.

Scale-Invariant Visual Capabilities Explained by Topographic Representations of Luminance and Texture in Primate V1.

Benvenuti G, Chen Y, Ramakrishnan C, Deisseroth K, Geisler WS, Seidemann E.

Neuron. 2018 Dec 19;100(6):1504-1512.e4. doi: 10.1016/j.neuron.2018.10.020. Epub 2018 Nov 1. Erratum in: Neuron. 2018 Dec 19;100(6):1533.

PMID:
30392796
17.

Structural mechanisms of selectivity and gating in anion channelrhodopsins.

Kato HE, Kim YS, Paggi JM, Evans KE, Allen WE, Richardson C, Inoue K, Ito S, Ramakrishnan C, Fenno LE, Yamashita K, Hilger D, Lee SY, Berndt A, Shen K, Kandori H, Dror RO, Kobilka BK, Deisseroth K.

Nature. 2018 Sep;561(7723):349-354. doi: 10.1038/s41586-018-0504-5. Epub 2018 Aug 29.

18.

Crystal structure of the natural anion-conducting channelrhodopsin GtACR1.

Kim YS, Kato HE, Yamashita K, Ito S, Inoue K, Ramakrishnan C, Fenno LE, Evans KE, Paggi JM, Dror RO, Kandori H, Kobilka BK, Deisseroth K.

Nature. 2018 Sep;561(7723):343-348. doi: 10.1038/s41586-018-0511-6. Epub 2018 Aug 29.

19.

The non-enzymatic RAS effector RASSF7 inhibits oncogenic c-Myc function.

Kumaraswamy A, Mamidi A, Desai P, Sivagnanam A, Perumalsamy LR, Ramakrishnan C, Gromiha M, Rajalingam K, Mahalingam S.

J Biol Chem. 2018 Oct 5;293(40):15691-15705. doi: 10.1074/jbc.RA118.004452. Epub 2018 Aug 23.

20.

Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches.

Poulin JF, Caronia G, Hofer C, Cui Q, Helm B, Ramakrishnan C, Chan CS, Dombeck DA, Deisseroth K, Awatramani R.

Nat Neurosci. 2018 Sep;21(9):1260-1271. doi: 10.1038/s41593-018-0203-4. Epub 2018 Aug 13.

21.

Three-dimensional intact-tissue sequencing of single-cell transcriptional states.

Wang X, Allen WE, Wright MA, Sylwestrak EL, Samusik N, Vesuna S, Evans K, Liu C, Ramakrishnan C, Liu J, Nolan GP, Bava FA, Deisseroth K.

Science. 2018 Jul 27;361(6400). pii: eaat5691. doi: 10.1126/science.aat5691. Epub 2018 Jun 21.

22.

Development of an optogenetic toolkit for neural circuit dissection in squirrel monkeys.

O'Shea DJ, Kalanithi P, Ferenczi EA, Hsueh B, Chandrasekaran C, Goo W, Diester I, Ramakrishnan C, Kaufman MT, Ryu SI, Yeom KW, Deisseroth K, Shenoy KV.

Sci Rep. 2018 Apr 30;8(1):6775. doi: 10.1038/s41598-018-24362-7.

23.

Sorting Through the Safety Data Haystack: Using Machine Learning to Identify Individual Case Safety Reports in Social-Digital Media.

Comfort S, Perera S, Hudson Z, Dorrell D, Meireis S, Nagarajan M, Ramakrishnan C, Fine J.

Drug Saf. 2018 Jun;41(6):579-590. doi: 10.1007/s40264-018-0641-7.

24.

RNA-Seq analysis during the life cycle of Cryptosporidium parvum reveals significant differential gene expression between proliferating stages in the intestine and infectious sporozoites.

Lippuner C, Ramakrishnan C, Basso WU, Schmid MW, Okoniewski M, Smith NC, Hässig M, Deplazes P, Hehl AB.

Int J Parasitol. 2018 May;48(6):413-422. doi: 10.1016/j.ijpara.2017.10.007. Epub 2018 Feb 9.

PMID:
29432770
25.

The central amygdala controls learning in the lateral amygdala.

Yu K, Ahrens S, Zhang X, Schiff H, Ramakrishnan C, Fenno L, Deisseroth K, Zhao F, Luo MH, Gong L, He M, Zhou P, Paninski L, Li B.

Nat Neurosci. 2017 Dec;20(12):1680-1685. doi: 10.1038/s41593-017-0009-9. Epub 2017 Oct 23.

26.

Long-Range GABAergic Inputs Regulate Neural Stem Cell Quiescence and Control Adult Hippocampal Neurogenesis.

Bao H, Asrican B, Li W, Gu B, Wen Z, Lim SA, Haniff I, Ramakrishnan C, Deisseroth K, Philpot B, Song J.

Cell Stem Cell. 2017 Nov 2;21(5):604-617.e5. doi: 10.1016/j.stem.2017.10.003.

27.

An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes.

Chiba S, Ishida T, Ikeda K, Mochizuki M, Teramoto R, Taguchi YH, Iwadate M, Umeyama H, Ramakrishnan C, Thangakani AM, Velmurugan D, Gromiha MM, Okuno T, Kato K, Minami S, Chikenji G, Suzuki SD, Yanagisawa K, Shin WH, Kihara D, Yamamoto KZ, Moriwaki Y, Yasuo N, Yoshino R, Zozulya S, Borysko P, Stavniichuk R, Honma T, Hirokawa T, Akiyama Y, Sekijima M.

Sci Rep. 2017 Sep 20;7(1):12038. doi: 10.1038/s41598-017-10275-4.

28.

Thirst-associated preoptic neurons encode an aversive motivational drive.

Allen WE, DeNardo LA, Chen MZ, Liu CD, Loh KM, Fenno LE, Ramakrishnan C, Deisseroth K, Luo L.

Science. 2017 Sep 15;357(6356):1149-1155. doi: 10.1126/science.aan6747.

29.

Place field assembly distribution encodes preferred locations.

Mamad O, Stumpp L, McNamara HM, Ramakrishnan C, Deisseroth K, Reilly RB, Tsanov M.

PLoS Biol. 2017 Sep 12;15(9):e2002365. doi: 10.1371/journal.pbio.2002365. eCollection 2017 Sep.

30.

Molecular and Circuit-Dynamical Identification of Top-Down Neural Mechanisms for Restraint of Reward Seeking.

Kim CK, Ye L, Jennings JH, Pichamoorthy N, Tang DD, Yoo AW, Ramakrishnan C, Deisseroth K.

Cell. 2017 Aug 24;170(5):1013-1027.e14. doi: 10.1016/j.cell.2017.07.020. Epub 2017 Aug 17.

31.

Developmental Dysfunction of VIP Interneurons Impairs Cortical Circuits.

Batista-Brito R, Vinck M, Ferguson KA, Chang JT, Laubender D, Lur G, Mossner JM, Hernandez VG, Ramakrishnan C, Deisseroth K, Higley MJ, Cardin JA.

Neuron. 2017 Aug 16;95(4):884-895.e9. doi: 10.1016/j.neuron.2017.07.034.

32.

Influence of Socioeconomic Factors on Daily Life Activities and Quality of Life of Thai Elderly.

Somrongthong R, Wongchalee S, Ramakrishnan C, Hongthong D, Yodmai K, Wongtongkam N.

J Public Health Res. 2017 Jun 22;6(1):862. doi: 10.4081/jphr.2017.862. eCollection 2017 Apr 13.

33.

Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2-deficient mice.

Selimbeyoglu A, Kim CK, Inoue M, Lee SY, Hong ASO, Kauvar I, Ramakrishnan C, Fenno LE, Davidson TJ, Wright M, Deisseroth K.

Sci Transl Med. 2017 Aug 2;9(401). pii: eaah6733. doi: 10.1126/scitranslmed.aah6733.

34.

A Guide to Creating and Testing New INTRSECT Constructs.

Fenno LE, Mattis J, Ramakrishnan C, Deisseroth K.

Curr Protoc Neurosci. 2017 Jul 5;80:4.39.1-4.39.24. doi: 10.1002/cpns.30.

PMID:
28678399
35.

Genome-wide analysis of gene expression and protein secretion of Babesia canis during virulent infection identifies potential pathogenicity factors.

Eichenberger RM, Ramakrishnan C, Russo G, Deplazes P, Hehl AB.

Sci Rep. 2017 Jun 13;7(1):3357. doi: 10.1038/s41598-017-03445-x.

36.

In Vivo Fiber Photometry Reveals Signature of Future Stress Susceptibility in Nucleus Accumbens.

Muir J, Lorsch ZS, Ramakrishnan C, Deisseroth K, Nestler EJ, Calipari ES, Bagot RC.

Neuropsychopharmacology. 2018 Jan;43(2):255-263. doi: 10.1038/npp.2017.122. Epub 2017 Jun 7.

37.

Identification of type I and type II inhibitors of c-Yes kinase using in silico and experimental techniques.

Ramakrishnan C, Mary Thangakani A, Velmurugan D, Anantha Krishnan D, Sekijima M, Akiyama Y, Gromiha MM.

J Biomol Struct Dyn. 2018 May;36(6):1566-1576. doi: 10.1080/07391102.2017.1329098. Epub 2017 Jun 7.

PMID:
28589758
38.

The merozoite-specific protein, TgGRA11B, identified as a component of the Toxoplasma gondii parasitophorous vacuole in a tachyzoite expression model.

Ramakrishnan C, Walker RA, Eichenberger RM, Hehl AB, Smith NC.

Int J Parasitol. 2017 Sep;47(10-11):597-600. doi: 10.1016/j.ijpara.2017.04.001. Epub 2017 May 17.

PMID:
28526607
39.

A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins.

François A, Low SA, Sypek EI, Christensen AJ, Sotoudeh C, Beier KT, Ramakrishnan C, Ritola KD, Sharif-Naeini R, Deisseroth K, Delp SL, Malenka RC, Luo L, Hantman AW, Scherrer G.

Neuron. 2017 Feb 22;93(4):822-839.e6. doi: 10.1016/j.neuron.2017.01.008. Epub 2017 Feb 2.

40.

Gamma oscillations organize top-down signalling to hypothalamus and enable food seeking.

Carus-Cadavieco M, Gorbati M, Ye L, Bender F, van der Veldt S, Kosse C, Börgers C, Lee SY, Ramakrishnan C, Hu Y, Denisova N, Ramm F, Volitaki E, Burdakov D, Deisseroth K, Ponomarenko A, Korotkova T.

Nature. 2017 Feb 9;542(7640):232-236. doi: 10.1038/nature21066. Epub 2017 Feb 1.

PMID:
28146472
41.

Dopaminergic dynamics underlying sex-specific cocaine reward.

Calipari ES, Juarez B, Morel C, Walker DM, Cahill ME, Ribeiro E, Roman-Ortiz C, Ramakrishnan C, Deisseroth K, Han MH, Nestler EJ.

Nat Commun. 2017 Jan 10;8:13877. doi: 10.1038/ncomms13877.

42.

Structure-function relationship of Chikungunya nsP2 protease: A comparative study with papain.

Ramakrishnan C, Kutumbarao NHV, Suhitha S, Velmurugan D.

Chem Biol Drug Des. 2017 May;89(5):772-782. doi: 10.1111/cbdd.12901. Epub 2017 Jan 5.

PMID:
28054451
43.

In Vivo Interrogation of Spinal Mechanosensory Circuits.

Christensen AJ, Iyer SM, François A, Vyas S, Ramakrishnan C, Vesuna S, Deisseroth K, Scherrer G, Delp SL.

Cell Rep. 2016 Nov 1;17(6):1699-1710. doi: 10.1016/j.celrep.2016.10.010.

44.

Celastrol modulates inflammation through inhibition of the catalytic activity of mediators of arachidonic acid pathway: Secretory phospholipase A2 group IIA, 5-lipoxygenase and cyclooxygenase-2.

Joshi V, Venkatesha SH, Ramakrishnan C, Nanjaraj Urs AN, Hiremath V, Moudgil KD, Velmurugan D, Vishwanath BS.

Pharmacol Res. 2016 Nov;113(Pt A):265-275. doi: 10.1016/j.phrs.2016.08.035. Epub 2016 Sep 3.

PMID:
27597642
45.

Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala.

Marcinkiewcz CA, Mazzone CM, D'Agostino G, Halladay LR, Hardaway JA, DiBerto JF, Navarro M, Burnham N, Cristiano C, Dorrier CE, Tipton GJ, Ramakrishnan C, Kozicz T, Deisseroth K, Thiele TE, McElligott ZA, Holmes A, Heisler LK, Kash TL.

Nature. 2016 Sep 1;537(7618):97-101. doi: 10.1038/nature19318. Epub 2016 Aug 24.

46.

Optogenetic and chemogenetic strategies for sustained inhibition of pain.

Iyer SM, Vesuna S, Ramakrishnan C, Huynh K, Young S, Berndt A, Lee SY, Gorini CJ, Deisseroth K, Delp SL.

Sci Rep. 2016 Aug 3;6:30570. doi: 10.1038/srep30570.

47.

Competition between engrams influences fear memory formation and recall.

Rashid AJ, Yan C, Mercaldo V, Hsiang HL, Park S, Cole CJ, De Cristofaro A, Yu J, Ramakrishnan C, Lee SY, Deisseroth K, Frankland PW, Josselyn SA.

Science. 2016 Jul 22;353(6297):383-7. doi: 10.1126/science.aaf0594.

48.

Intramolecular backbone···backbone hydrogen bonds in polypeptide conformations. The other way around: ɛ-turn.

Toniolo C, Crisma M, Formaggio F, Alemán C, Ramakrishnan C, Kalmankar N, Balaram P.

Biopolymers. 2017 Jan;108(1). doi: 10.1002/bip.22911. Review.

PMID:
27404945
49.

Midbrain circuits for defensive behaviour.

Tovote P, Esposito MS, Botta P, Chaudun F, Fadok JP, Markovic M, Wolff SB, Ramakrishnan C, Fenno L, Deisseroth K, Herry C, Arber S, Lüthi A.

Nature. 2016 Jun 9;534(7606):206-12. doi: 10.1038/nature17996. Epub 2016 Jun 1.

PMID:
27279213
50.

Endocannabinoid Modulation of Orbitostriatal Circuits Gates Habit Formation.

Gremel CM, Chancey JH, Atwood BK, Luo G, Neve R, Ramakrishnan C, Deisseroth K, Lovinger DM, Costa RM.

Neuron. 2016 Jun 15;90(6):1312-1324. doi: 10.1016/j.neuron.2016.04.043. Epub 2016 May 26.

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