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Items: 1 to 50 of 306

1.

Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches.

Poulin JF, Caronia G, Hofer C, Cui Q, Helm B, Ramakrishnan C, Chan CS, Dombeck DA, Deisseroth K, Awatramani R.

Nat Neurosci. 2018 Aug 13. doi: 10.1038/s41593-018-0203-4. [Epub ahead of print]

PMID:
30104732
2.

Three-dimensional intact-tissue sequencing of single-cell transcriptional states.

Wang X, Allen WE, Wright MA, Sylwestrak EL, Samusik N, Vesuna S, Evans K, Liu C, Ramakrishnan C, Liu J, Nolan GP, Bava FA, Deisseroth K.

Science. 2018 Jul 27;361(6400). pii: eaat5691. doi: 10.1126/science.aat5691. Epub 2018 Jun 21.

PMID:
29930089
3.

Development of an optogenetic toolkit for neural circuit dissection in squirrel monkeys.

O'Shea DJ, Kalanithi P, Ferenczi EA, Hsueh B, Chandrasekaran C, Goo W, Diester I, Ramakrishnan C, Kaufman MT, Ryu SI, Yeom KW, Deisseroth K, Shenoy KV.

Sci Rep. 2018 Apr 30;8(1):6775. doi: 10.1038/s41598-018-24362-7.

4.

Sorting Through the Safety Data Haystack: Using Machine Learning to Identify Individual Case Safety Reports in Social-Digital Media.

Comfort S, Perera S, Hudson Z, Dorrell D, Meireis S, Nagarajan M, Ramakrishnan C, Fine J.

Drug Saf. 2018 Jun;41(6):579-590. doi: 10.1007/s40264-018-0641-7.

5.

RNA-Seq analysis during the life cycle of Cryptosporidium parvum reveals significant differential gene expression between proliferating stages in the intestine and infectious sporozoites.

Lippuner C, Ramakrishnan C, Basso WU, Schmid MW, Okoniewski M, Smith NC, Hässig M, Deplazes P, Hehl AB.

Int J Parasitol. 2018 May;48(6):413-422. doi: 10.1016/j.ijpara.2017.10.007. Epub 2018 Feb 9.

PMID:
29432770
6.

The central amygdala controls learning in the lateral amygdala.

Yu K, Ahrens S, Zhang X, Schiff H, Ramakrishnan C, Fenno L, Deisseroth K, Zhao F, Luo MH, Gong L, He M, Zhou P, Paninski L, Li B.

Nat Neurosci. 2017 Dec;20(12):1680-1685. doi: 10.1038/s41593-017-0009-9. Epub 2017 Oct 23.

7.

Long-Range GABAergic Inputs Regulate Neural Stem Cell Quiescence and Control Adult Hippocampal Neurogenesis.

Bao H, Asrican B, Li W, Gu B, Wen Z, Lim SA, Haniff I, Ramakrishnan C, Deisseroth K, Philpot B, Song J.

Cell Stem Cell. 2017 Nov 2;21(5):604-617.e5. doi: 10.1016/j.stem.2017.10.003.

PMID:
29100013
8.

An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes.

Chiba S, Ishida T, Ikeda K, Mochizuki M, Teramoto R, Taguchi YH, Iwadate M, Umeyama H, Ramakrishnan C, Thangakani AM, Velmurugan D, Gromiha MM, Okuno T, Kato K, Minami S, Chikenji G, Suzuki SD, Yanagisawa K, Shin WH, Kihara D, Yamamoto KZ, Moriwaki Y, Yasuo N, Yoshino R, Zozulya S, Borysko P, Stavniichuk R, Honma T, Hirokawa T, Akiyama Y, Sekijima M.

Sci Rep. 2017 Sep 20;7(1):12038. doi: 10.1038/s41598-017-10275-4.

9.

Thirst-associated preoptic neurons encode an aversive motivational drive.

Allen WE, DeNardo LA, Chen MZ, Liu CD, Loh KM, Fenno LE, Ramakrishnan C, Deisseroth K, Luo L.

Science. 2017 Sep 15;357(6356):1149-1155. doi: 10.1126/science.aan6747.

10.

Place field assembly distribution encodes preferred locations.

Mamad O, Stumpp L, McNamara HM, Ramakrishnan C, Deisseroth K, Reilly RB, Tsanov M.

PLoS Biol. 2017 Sep 12;15(9):e2002365. doi: 10.1371/journal.pbio.2002365. eCollection 2017 Sep.

11.

Molecular and Circuit-Dynamical Identification of Top-Down Neural Mechanisms for Restraint of Reward Seeking.

Kim CK, Ye L, Jennings JH, Pichamoorthy N, Tang DD, Yoo AW, Ramakrishnan C, Deisseroth K.

Cell. 2017 Aug 24;170(5):1013-1027.e14. doi: 10.1016/j.cell.2017.07.020. Epub 2017 Aug 17.

12.

Developmental Dysfunction of VIP Interneurons Impairs Cortical Circuits.

Batista-Brito R, Vinck M, Ferguson KA, Chang JT, Laubender D, Lur G, Mossner JM, Hernandez VG, Ramakrishnan C, Deisseroth K, Higley MJ, Cardin JA.

Neuron. 2017 Aug 16;95(4):884-895.e9. doi: 10.1016/j.neuron.2017.07.034.

13.

Influence of Socioeconomic Factors on Daily Life Activities and Quality of Life of Thai Elderly.

Somrongthong R, Wongchalee S, Ramakrishnan C, Hongthong D, Yodmai K, Wongtongkam N.

J Public Health Res. 2017 Jun 22;6(1):862. doi: 10.4081/jphr.2017.862. eCollection 2017 Apr 13.

14.

Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2-deficient mice.

Selimbeyoglu A, Kim CK, Inoue M, Lee SY, Hong ASO, Kauvar I, Ramakrishnan C, Fenno LE, Davidson TJ, Wright M, Deisseroth K.

Sci Transl Med. 2017 Aug 2;9(401). pii: eaah6733. doi: 10.1126/scitranslmed.aah6733.

15.

A Guide to Creating and Testing New INTRSECT Constructs.

Fenno LE, Mattis J, Ramakrishnan C, Deisseroth K.

Curr Protoc Neurosci. 2017 Jul 5;80:4.39.1-4.39.24. doi: 10.1002/cpns.30.

PMID:
28678399
16.

Genome-wide analysis of gene expression and protein secretion of Babesia canis during virulent infection identifies potential pathogenicity factors.

Eichenberger RM, Ramakrishnan C, Russo G, Deplazes P, Hehl AB.

Sci Rep. 2017 Jun 13;7(1):3357. doi: 10.1038/s41598-017-03445-x.

17.

In Vivo Fiber Photometry Reveals Signature of Future Stress Susceptibility in Nucleus Accumbens.

Muir J, Lorsch ZS, Ramakrishnan C, Deisseroth K, Nestler EJ, Calipari ES, Bagot RC.

Neuropsychopharmacology. 2018 Jan;43(2):255-263. doi: 10.1038/npp.2017.122. Epub 2017 Jun 7.

PMID:
28589967
18.

Identification of type I and type II inhibitors of c-Yes kinase using in silico and experimental techniques.

Ramakrishnan C, Mary Thangakani A, Velmurugan D, Anantha Krishnan D, Sekijima M, Akiyama Y, Gromiha MM.

J Biomol Struct Dyn. 2018 May;36(6):1566-1576. doi: 10.1080/07391102.2017.1329098. Epub 2017 Jun 7.

PMID:
28589758
19.

The merozoite-specific protein, TgGRA11B, identified as a component of the Toxoplasma gondii parasitophorous vacuole in a tachyzoite expression model.

Ramakrishnan C, Walker RA, Eichenberger RM, Hehl AB, Smith NC.

Int J Parasitol. 2017 Sep;47(10-11):597-600. doi: 10.1016/j.ijpara.2017.04.001. Epub 2017 May 17.

PMID:
28526607
20.

A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins.

François A, Low SA, Sypek EI, Christensen AJ, Sotoudeh C, Beier KT, Ramakrishnan C, Ritola KD, Sharif-Naeini R, Deisseroth K, Delp SL, Malenka RC, Luo L, Hantman AW, Scherrer G.

Neuron. 2017 Feb 22;93(4):822-839.e6. doi: 10.1016/j.neuron.2017.01.008. Epub 2017 Feb 2.

21.

Gamma oscillations organize top-down signalling to hypothalamus and enable food seeking.

Carus-Cadavieco M, Gorbati M, Ye L, Bender F, van der Veldt S, Kosse C, Börgers C, Lee SY, Ramakrishnan C, Hu Y, Denisova N, Ramm F, Volitaki E, Burdakov D, Deisseroth K, Ponomarenko A, Korotkova T.

Nature. 2017 Feb 9;542(7640):232-236. doi: 10.1038/nature21066. Epub 2017 Feb 1.

PMID:
28146472
22.

Dopaminergic dynamics underlying sex-specific cocaine reward.

Calipari ES, Juarez B, Morel C, Walker DM, Cahill ME, Ribeiro E, Roman-Ortiz C, Ramakrishnan C, Deisseroth K, Han MH, Nestler EJ.

Nat Commun. 2017 Jan 10;8:13877. doi: 10.1038/ncomms13877.

23.

Structure-function relationship of Chikungunya nsP2 protease: A comparative study with papain.

Ramakrishnan C, Kutumbarao NHV, Suhitha S, Velmurugan D.

Chem Biol Drug Des. 2017 May;89(5):772-782. doi: 10.1111/cbdd.12901. Epub 2017 Jan 5.

PMID:
28054451
24.

In Vivo Interrogation of Spinal Mechanosensory Circuits.

Christensen AJ, Iyer SM, François A, Vyas S, Ramakrishnan C, Vesuna S, Deisseroth K, Scherrer G, Delp SL.

Cell Rep. 2016 Nov 1;17(6):1699-1710. doi: 10.1016/j.celrep.2016.10.010.

25.

Celastrol modulates inflammation through inhibition of the catalytic activity of mediators of arachidonic acid pathway: Secretory phospholipase A2 group IIA, 5-lipoxygenase and cyclooxygenase-2.

Joshi V, Venkatesha SH, Ramakrishnan C, Nanjaraj Urs AN, Hiremath V, Moudgil KD, Velmurugan D, Vishwanath BS.

Pharmacol Res. 2016 Nov;113(Pt A):265-275. doi: 10.1016/j.phrs.2016.08.035. Epub 2016 Sep 3.

PMID:
27597642
26.

Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala.

Marcinkiewcz CA, Mazzone CM, D'Agostino G, Halladay LR, Hardaway JA, DiBerto JF, Navarro M, Burnham N, Cristiano C, Dorrier CE, Tipton GJ, Ramakrishnan C, Kozicz T, Deisseroth K, Thiele TE, McElligott ZA, Holmes A, Heisler LK, Kash TL.

Nature. 2016 Sep 1;537(7618):97-101. doi: 10.1038/nature19318. Epub 2016 Aug 24.

27.

Optogenetic and chemogenetic strategies for sustained inhibition of pain.

Iyer SM, Vesuna S, Ramakrishnan C, Huynh K, Young S, Berndt A, Lee SY, Gorini CJ, Deisseroth K, Delp SL.

Sci Rep. 2016 Aug 3;6:30570. doi: 10.1038/srep30570.

28.

Competition between engrams influences fear memory formation and recall.

Rashid AJ, Yan C, Mercaldo V, Hsiang HL, Park S, Cole CJ, De Cristofaro A, Yu J, Ramakrishnan C, Lee SY, Deisseroth K, Frankland PW, Josselyn SA.

Science. 2016 Jul 22;353(6297):383-7. doi: 10.1126/science.aaf0594.

29.

Intramolecular backbone···backbone hydrogen bonds in polypeptide conformations. The other way around: ɛ-turn.

Toniolo C, Crisma M, Formaggio F, Alemán C, Ramakrishnan C, Kalmankar N, Balaram P.

Biopolymers. 2017 Jan;108(1). doi: 10.1002/bip.22911. Review.

PMID:
27404945
30.

Midbrain circuits for defensive behaviour.

Tovote P, Esposito MS, Botta P, Chaudun F, Fadok JP, Markovic M, Wolff SB, Ramakrishnan C, Fenno L, Deisseroth K, Herry C, Arber S, Lüthi A.

Nature. 2016 Jun 9;534(7606):206-12. doi: 10.1038/nature17996. Epub 2016 Jun 1.

PMID:
27279213
31.

Endocannabinoid Modulation of Orbitostriatal Circuits Gates Habit Formation.

Gremel CM, Chancey JH, Atwood BK, Luo G, Neve R, Ramakrishnan C, Deisseroth K, Lovinger DM, Costa RM.

Neuron. 2016 Jun 15;90(6):1312-1324. doi: 10.1016/j.neuron.2016.04.043. Epub 2016 May 26.

32.

Wiring and Molecular Features of Prefrontal Ensembles Representing Distinct Experiences.

Ye L, Allen WE, Thompson KR, Tian Q, Hsueh B, Ramakrishnan C, Wang AC, Jennings JH, Adhikari A, Halpern CH, Witten IB, Barth AL, Luo L, McNab JA, Deisseroth K.

Cell. 2016 Jun 16;165(7):1776-1788. doi: 10.1016/j.cell.2016.05.010. Epub 2016 May 26.

33.

Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2, lipoxygenase and cyclooxygenase.

Joshi V, Umashankara M, Ramakrishnan C, Nanjaraj Urs AN, Suvilesh KN, Velmurugan D, Rangappa KS, Vishwanath BS.

Arch Biochem Biophys. 2016 May 15;598:28-39. doi: 10.1016/j.abb.2016.04.003. Epub 2016 Apr 6.

PMID:
27060751
34.

Optogenetic approaches addressing extracellular modulation of neural excitability.

Ferenczi EA, Vierock J, Atsuta-Tsunoda K, Tsunoda SP, Ramakrishnan C, Gorini C, Thompson K, Lee SY, Berndt A, Perry C, Minniberger S, Vogt A, Mattis J, Prakash R, Delp S, Deisseroth K, Hegemann P.

Sci Rep. 2016 Apr 5;6:23947. doi: 10.1038/srep23947.

35.

Nucleus accumbens D2R cells signal prior outcomes and control risky decision-making.

Zalocusky KA, Ramakrishnan C, Lerner TN, Davidson TJ, Knutson B, Deisseroth K.

Nature. 2016 Mar 31;531(7596):642-6. doi: 10.1038/nature17400. Epub 2016 Mar 23.

36.

Discovery of a tyrosine-rich sporocyst wall protein in Eimeria tenella.

Walker RA, Niepceron A, Ramakrishnan C, Sedano L, Hehl AB, Brossier F, Smith NC.

Parasit Vectors. 2016 Mar 2;9:124. doi: 10.1186/s13071-016-1410-z.

37.

Simultaneous fast measurement of circuit dynamics at multiple sites across the mammalian brain.

Kim CK, Yang SJ, Pichamoorthy N, Young NP, Kauvar I, Jennings JH, Lerner TN, Berndt A, Lee SY, Ramakrishnan C, Davidson TJ, Inoue M, Bito H, Deisseroth K.

Nat Methods. 2016 Apr;13(4):325-8. doi: 10.1038/nmeth.3770. Epub 2016 Feb 15.

38.

In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward.

Calipari ES, Bagot RC, Purushothaman I, Davidson TJ, Yorgason JT, Peña CJ, Walker DM, Pirpinias ST, Guise KG, Ramakrishnan C, Deisseroth K, Nestler EJ.

Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):2726-31. doi: 10.1073/pnas.1521238113. Epub 2016 Feb 1.

39.

Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior.

Ferenczi EA, Zalocusky KA, Liston C, Grosenick L, Warden MR, Amatya D, Katovich K, Mehta H, Patenaude B, Ramakrishnan C, Kalanithi P, Etkin A, Knutson B, Glover GH, Deisseroth K.

Science. 2016 Jan 1;351(6268):aac9698. doi: 10.1126/science.aac9698.

40.

Structural foundations of optogenetics: Determinants of channelrhodopsin ion selectivity.

Berndt A, Lee SY, Wietek J, Ramakrishnan C, Steinberg EE, Rashid AJ, Kim H, Park S, Santoro A, Frankland PW, Iyer SM, Pak S, Ährlund-Richter S, Delp SL, Malenka RC, Josselyn SA, Carlén M, Hegemann P, Deisseroth K.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):822-9. doi: 10.1073/pnas.1523341113. Epub 2015 Dec 22.

41.

Identification of potential inhibitors based on compound proposal contest: Tyrosine-protein kinase Yes as a target.

Chiba S, Ikeda K, Ishida T, Gromiha MM, Taguchi YH, Iwadate M, Umeyama H, Hsin KY, Kitano H, Yamamoto K, Sugaya N, Kato K, Okuno T, Chikenji G, Mochizuki M, Yasuo N, Yoshino R, Yanagisawa K, Ban T, Teramoto R, Ramakrishnan C, Thangakani AM, Velmurugan D, Prathipati P, Ito J, Tsuchiya Y, Mizuguchi K, Honma T, Hirokawa T, Akiyama Y, Sekijima M.

Sci Rep. 2015 Nov 26;5:17209. doi: 10.1038/srep17209.

42.

openBIS ELN-LIMS: an open-source database for academic laboratories.

Barillari C, Ottoz DS, Fuentes-Serna JM, Ramakrishnan C, Rinn B, Rudolf F.

Bioinformatics. 2016 Feb 15;32(4):638-40. doi: 10.1093/bioinformatics/btv606. Epub 2015 Oct 27.

43.

Projections from neocortex mediate top-down control of memory retrieval.

Rajasethupathy P, Sankaran S, Marshel JH, Kim CK, Ferenczi E, Lee SY, Berndt A, Ramakrishnan C, Jaffe A, Lo M, Liston C, Deisseroth K.

Nature. 2015 Oct 29;526(7575):653-9. doi: 10.1038/nature15389. Epub 2015 Oct 5.

44.

Progressive Hemorrhage and Myotoxicity Induced by Echis carinatus Venom in Murine Model: Neutralization by Inhibitor Cocktail of N,N,N',N'-Tetrakis (2-Pyridylmethyl) Ethane-1,2-Diamine and Silymarin.

Nanjaraj Urs AN, Ramakrishnan C, Joshi V, Suvilesh KN, Veerabasappa Gowda T, Velmurugan D, Vishwanath BS.

PLoS One. 2015 Aug 14;10(8):e0135843. doi: 10.1371/journal.pone.0135843. eCollection 2015.

45.

Peptide δ-Turn: Literature Survey and Recent Progress.

Toniolo C, Crisma M, Moretto A, Peggion C, Formaggio F, Alemán C, Cativiela C, Ramakrishnan C, Balaram P.

Chemistry. 2015 Sep 28;21(40):13866-77. doi: 10.1002/chem.201501467. Epub 2015 Aug 4.

PMID:
26243713
46.

Optogenetic Stimulation of Neural Grafts Enhances Neurotransmission and Downregulates the Inflammatory Response in Experimental Stroke Model.

Daadi MM, Klausner JQ, Bajar B, Goshen I, Lee-Messer C, Lee SY, Winge MC, Ramakrishnan C, Lo M, Sun G, Deisseroth K, Steinberg GK.

Cell Transplant. 2016;25(7):1371-80. doi: 10.3727/096368915X688533. Epub 2015 Jun 30.

47.

Identifying a potential receptor for the antibacterial peptide of sponge Axinella donnani endosymbiont.

Vimala A, Ramakrishnan C, Gromiha MM.

Gene. 2015 Jul 25;566(2):166-74. doi: 10.1016/j.gene.2015.04.070. Epub 2015 May 2.

PMID:
25939848
48.

Structure based approach for understanding organism specific recognition of protein-RNA complexes.

Nagarajan R, Chothani SP, Ramakrishnan C, Sekijima M, Gromiha MM.

Biol Direct. 2015 Mar 7;10:8. doi: 10.1186/s13062-015-0039-8.

49.

RNA Seq analysis of the Eimeria tenella gametocyte transcriptome reveals clues about the molecular basis for sexual reproduction and oocyst biogenesis.

Walker RA, Sharman PA, Miller CM, Lippuner C, Okoniewski M, Eichenberger RM, Ramakrishnan C, Brossier F, Deplazes P, Hehl AB, Smith NC.

BMC Genomics. 2015 Feb 18;16:94. doi: 10.1186/s12864-015-1298-6.

50.

Asexual expansion of Toxoplasma gondii merozoites is distinct from tachyzoites and entails expression of non-overlapping gene families to attach, invade, and replicate within feline enterocytes.

Hehl AB, Basso WU, Lippuner C, Ramakrishnan C, Okoniewski M, Walker RA, Grigg ME, Smith NC, Deplazes P.

BMC Genomics. 2015 Feb 13;16:66. doi: 10.1186/s12864-015-1225-x.

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