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Items: 19


T3 Induces Both Markers of Maturation and Aging in Pancreatic β-Cells.

Aguayo-Mazzucato C, Lee TB Jr, Matzko M, DiIenno A, Rezanejad H, Ramadoss P, Scanlan T, Zavacki AM, Larsen PR, Hollenberg A, Colton C, Sharma A, Bonner-Weir S.

Diabetes. 2018 Jul;67(7):1322-1331. doi: 10.2337/db18-0030. Epub 2018 Apr 6.


Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production.

Hine C, Kim HJ, Zhu Y, Harputlugil E, Longchamp A, Matos MS, Ramadoss P, Bauerle K, Brace L, Asara JM, Ozaki CK, Cheng SY, Singha S, Ahn KH, Kimmelman A, Fisher FM, Pissios P, Withers DJ, Selman C, Wang R, Yen K, Longo VD, Cohen P, Bartke A, Kopchick JJ, Miller R, Hollenberg AN, Mitchell JR.

Cell Metab. 2017 Jun 6;25(6):1320-1333.e5. doi: 10.1016/j.cmet.2017.05.003.


Liganded Thyroid Hormone Receptors Transactivate the DNA Methyltransferase 3a Gene in Mouse Neuronal Cells.

Kyono Y, Subramani A, Ramadoss P, Hollenberg AN, Bonett RM, Denver RJ.

Endocrinology. 2016 Sep;157(9):3647-57. doi: 10.1210/en.2015-1529. Epub 2016 Jul 7.


Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TRβ1-governed pathway.

Astapova I, Ramadoss P, Costa-e-Sousa RH, Ye F, Holtz KA, Li Y, Niepel MW, Cohen DE, Hollenberg AN.

J Clin Invest. 2014 May;124(5):1976-86. doi: 10.1172/JCI73419. Epub 2014 Apr 8.


Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.

Vella KR, Ramadoss P, Costa-E-Sousa RH, Astapova I, Ye FD, Holtz KA, Harris JC, Hollenberg AN.

Mol Cell Biol. 2014 May;34(9):1564-75. doi: 10.1128/MCB.00129-14. Epub 2014 Feb 18.


Novel mechanism of positive versus negative regulation by thyroid hormone receptor β1 (TRβ1) identified by genome-wide profiling of binding sites in mouse liver.

Ramadoss P, Abraham BJ, Tsai L, Zhou Y, Costa-e-Sousa RH, Ye F, Bilban M, Zhao K, Hollenberg AN.

J Biol Chem. 2014 Jan 17;289(3):1313-28. doi: 10.1074/jbc.M113.521450. Epub 2013 Nov 27.


Family members CREB and CREM control thyrotropin-releasing hormone (TRH) expression in the hypothalamus.

Chiappini F, Ramadoss P, Vella KR, Cunha LL, Ye FD, Stuart RC, Nillni EA, Hollenberg AN.

Mol Cell Endocrinol. 2013 Jan 5;365(1):84-94. doi: 10.1016/j.mce.2012.09.006. Epub 2012 Sep 20.


NPY and MC4R signaling regulate thyroid hormone levels during fasting through both central and peripheral pathways.

Vella KR, Ramadoss P, Lam FS, Harris JC, Ye FD, Same PD, O'Neill NF, Maratos-Flier E, Hollenberg AN.

Cell Metab. 2011 Dec 7;14(6):780-90. doi: 10.1016/j.cmet.2011.10.009. Epub 2011 Nov 17.


The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis.

Astapova I, Vella KR, Ramadoss P, Holtz KA, Rodwin BA, Liao XH, Weiss RE, Rosenberg MA, Rosenzweig A, Hollenberg AN.

Mol Endocrinol. 2011 Feb;25(2):212-24. doi: 10.1210/me.2010-0462. Epub 2011 Jan 14.


Regulation of hepatic six transmembrane epithelial antigen of prostate 4 (STEAP4) expression by STAT3 and CCAAT/enhancer-binding protein alpha.

Ramadoss P, Chiappini F, Bilban M, Hollenberg AN.

J Biol Chem. 2010 May 28;285(22):16453-66. doi: 10.1074/jbc.M109.066936. Epub 2010 Mar 19.


STAT3 targets the regulatory regions of gluconeogenic genes in vivo.

Ramadoss P, Unger-Smith NE, Lam FS, Hollenberg AN.

Mol Endocrinol. 2009 Jun;23(6):827-37. doi: 10.1210/me.2008-0264. Epub 2009 Mar 5.


Inflammatory signaling and aryl hydrocarbon receptor mediate synergistic induction of interleukin 6 in MCF-7 cells.

Hollingshead BD, Beischlag TV, Dinatale BC, Ramadoss P, Perdew GH.

Cancer Res. 2008 May 15;68(10):3609-17. doi: 10.1158/0008-5472.CAN-07-6168.


Role of the aryl hydrocarbon receptor in drug metabolism.

Ramadoss P, Marcus C, Perdew GH.

Expert Opin Drug Metab Toxicol. 2005 Jun;1(1):9-21. Review.


Evidence that ligand binding is a key determinant of Ah receptor-mediated transcriptional activity.

Murray IA, Reen RK, Leathery N, Ramadoss P, Bonati L, Gonzalez FJ, Peters JM, Perdew GH.

Arch Biochem Biophys. 2005 Oct 1;442(1):59-71.


Divergent roles of hepatitis B virus X-associated protein 2 (XAP2) in human versus mouse Ah receptor complexes.

Ramadoss P, Petrulis JR, Hollingshead BD, Kusnadi A, Perdew GH.

Biochemistry. 2004 Jan 27;43(3):700-9.


The hsp90 Co-chaperone XAP2 alters importin beta recognition of the bipartite nuclear localization signal of the Ah receptor and represses transcriptional activity.

Petrulis JR, Kusnadi A, Ramadoss P, Hollingshead B, Perdew GH.

J Biol Chem. 2003 Jan 24;278(4):2677-85. Epub 2002 Nov 12.


The Q-rich subdomain of the human Ah receptor transactivation domain is required for dioxin-mediated transcriptional activity.

Kumar MB, Ramadoss P, Reen RK, Vanden Heuvel JP, Perdew GH.

J Biol Chem. 2001 Nov 9;276(45):42302-10. Epub 2001 Sep 10.

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