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Items: 1 to 50 of 123

1.

Targeting Artificial Tumor Stromal Targets for Molecular Imaging of Tumor Vascular Hypoxia.

Koonce NA, Levy J, Hardee ME, Jamshidi-Parsian A, Vang KB, Sharma S, Raleigh JA, Dings RP, Griffin RJ.

PLoS One. 2015 Aug 26;10(8):e0135607. doi: 10.1371/journal.pone.0135607. eCollection 2015.

2.

Evaluation and immunohistochemical qualification of carbogen-induced ΔR₂ as a noninvasive imaging biomarker of improved tumor oxygenation.

Baker LC, Boult JK, Jamin Y, Gilmour LD, Walker-Samuel S, Burrell JS, Ashcroft M, Howe FA, Griffiths JR, Raleigh JA, van der Kogel AJ, Robinson SP.

Int J Radiat Oncol Biol Phys. 2013 Sep 1;87(1):160-7. doi: 10.1016/j.ijrobp.2013.04.051. Epub 2013 Jul 9.

PMID:
23849692
3.

Hypoxia regulation of phosphokinases and the prognostic value of pAKT in breast cancer.

Wennemers M, Stegeman H, Bussink J, Versleijen-Jonkers YM, van Laarhoven HW, Raleigh JA, Varia MA, Sweep FC, Span PN.

Int J Biol Markers. 2013 Jun 28;28(2):151-60. doi: 10.5301/jbm.5000008.

PMID:
23558942
4.

Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response.

Wennemers M, Bussink J, Scheijen B, Nagtegaal ID, van Laarhoven HW, Raleigh JA, Varia MA, Heuvel JJ, Rouschop KM, Sweep FC, Span PN.

Breast Cancer Res. 2011 Aug 24;13(4):R82. doi: 10.1186/bcr2934.

5.

Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates.

Via LE, Lin PL, Ray SM, Carrillo J, Allen SS, Eum SY, Taylor K, Klein E, Manjunatha U, Gonzales J, Lee EG, Park SK, Raleigh JA, Cho SN, McMurray DN, Flynn JL, Barry CE 3rd.

Infect Immun. 2008 Jun;76(6):2333-40. doi: 10.1128/IAI.01515-07. Epub 2008 Mar 17.

6.

Pimonidazole labelling and response to fractionated irradiation of five human squamous cell carcinoma (hSCC) lines in nude mice: the need for a multivariate approach in biomarker studies.

Yaromina A, Zips D, Thames HD, Eicheler W, Krause M, Rosner A, Haase M, Petersen C, Raleigh JA, Quennet V, Walenta S, Mueller-Klieser W, Baumann M.

Radiother Oncol. 2006 Nov;81(2):122-9. Epub 2006 Sep 7.

PMID:
16956683
7.

The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: a prospective international multi-center study.

Nordsmark M, Loncaster J, Aquino-Parsons C, Chou SC, Gebski V, West C, Lindegaard JC, Havsteen H, Davidson SE, Hunter R, Raleigh JA, Overgaard J.

Radiother Oncol. 2006 Aug;80(2):123-31. Epub 2006 Aug 4.

PMID:
16890316
8.

Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix.

Jankovic B, Aquino-Parsons C, Raleigh JA, Stanbridge EJ, Durand RE, Banath JP, MacPhail SH, Olive PL.

Cytometry B Clin Cytom. 2006 Mar;70(2):45-55.

9.

A comparison of oral and intravenous pimonidazole in canine tumors using intravenous CCI-103F as a control hypoxia marker.

Kleiter MM, Thrall DE, Malarkey DE, Ji X, Lee DY, Chou SC, Raleigh JA.

Int J Radiat Oncol Biol Phys. 2006 Feb 1;64(2):592-602. Epub 2005 Nov 14.

PMID:
16289910
10.

Hypoxic cell turnover in different solid tumor lines.

Ljungkvist AS, Bussink J, Kaanders JH, Rijken PF, Begg AC, Raleigh JA, van der Kogel AJ.

Int J Radiat Oncol Biol Phys. 2005 Jul 15;62(4):1157-68.

PMID:
15913908
11.

Erythropoietin and erythropoietin receptor expression in head and neck cancer: relationship to tumor hypoxia.

Arcasoy MO, Amin K, Chou SC, Haroon ZA, Varia M, Raleigh JA.

Clin Cancer Res. 2005 Jan 1;11(1):20-7.

12.
13.

Hypoxia and differentiation in squamous cell carcinomas of the uterine cervix: pimonidazole and involucrin.

Azuma Y, Chou SC, Lininger RA, Murphy BJ, Varia MA, Raleigh JA.

Clin Cancer Res. 2003 Oct 15;9(13):4944-52.

14.

Chronic intragastric alcohol exposure causes hypoxia and oxidative stress in the rat pancreas.

McKim SE, Uesugi T, Raleigh JA, McClain CJ, Arteel GE.

Arch Biochem Biophys. 2003 Sep 1;417(1):34-43.

PMID:
12921777
15.

Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas.

Nordsmark M, Loncaster J, Aquino-Parsons C, Chou SC, Ladekarl M, Havsteen H, Lindegaard JC, Davidson SE, Varia M, West C, Hunter R, Overgaard J, Raleigh JA.

Radiother Oncol. 2003 Apr;67(1):35-44.

PMID:
12758238
16.

GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: relationship to pimonidazole binding.

Airley RE, Loncaster J, Raleigh JA, Harris AL, Davidson SE, Hunter RD, West CM, Stratford IJ.

Int J Cancer. 2003 Mar 10;104(1):85-91.

17.

Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer.

Kaanders JH, Wijffels KI, Marres HA, Ljungkvist AS, Pop LA, van den Hoogen FJ, de Wilde PC, Bussink J, Raleigh JA, van der Kogel AJ.

Cancer Res. 2002 Dec 1;62(23):7066-74.

18.

Orally administered pimonidazole to label hypoxic tumor cells.

Bennewith KL, Raleigh JA, Durand RE.

Cancer Res. 2002 Dec 1;62(23):6827-30.

19.

HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors.

Janssen HL, Haustermans KM, Sprong D, Blommestijn G, Hofland I, Hoebers FJ, Blijweert E, Raleigh JA, Semenza GL, Varia MA, Balm AJ, van Velthuysen ML, Delaere P, Sciot R, Begg AC.

Int J Radiat Oncol Biol Phys. 2002 Dec 1;54(5):1537-49.

PMID:
12459383
20.

Synergy between vascular targeting agents and antibody-directed therapy.

Pedley RB, El-Emir E, Flynn AA, Boxer GM, Dearling J, Raleigh JA, Hill SA, Stuart S, Motha R, Begent RH.

Int J Radiat Oncol Biol Phys. 2002 Dec 1;54(5):1524-31.

PMID:
12459381
21.

Functional significance of erythropoietin receptor expression in breast cancer.

Arcasoy MO, Amin K, Karayal AF, Chou SC, Raleigh JA, Varia MA, Haroon ZA.

Lab Invest. 2002 Jul;82(7):911-8.

22.

Tumor-specific regulation of angiogenic growth factors and their receptors during recovery from cytotoxic therapy.

Taylor AP, Osorio L, Craig R, Raleigh JA, Ying Z, Goldenberg DM, Blumenthal RD.

Clin Cancer Res. 2002 Apr;8(4):1213-22.

23.

Hypoxia and perfusion measurements in human tumors--initial experience with pimonidazole and IUdR.

Begg AC, Janssen H, Sprong D, Hofland I, Blommestijn G, Raleigh JA, Varia M, Balm A, Van Velthuyzen L, Delaere P, Sciot R, Haustermans KMG.

Acta Oncol. 2001;40(8):924-8.

PMID:
11845956
24.

Protective effect of glycine on renal injury induced by ischemia-reperfusion in vivo.

Yin M, Zhong Z, Connor HD, Bunzendahl H, Finn WF, Rusyn I, Li X, Raleigh JA, Mason RP, Thurman RG.

Am J Physiol Renal Physiol. 2002 Mar;282(3):F417-23.

25.

Carbonic anhydrase 9 as an endogenous marker for hypoxic cells in cervical cancer.

Olive PL, Aquino-Parsons C, MacPhail SH, Liao SY, Raleigh JA, Lerman MI, Stanbridge EJ.

Cancer Res. 2001 Dec 15;61(24):8924-9.

26.

Optimizing the use of combined radioimmunotherapy and hypoxic cytotoxin therapy as a function of tumor hypoxia.

Blumenthal RD, Taylor A, Osorio L, Ochakovskaya R, Raleigh JA, Papadopoulou M, Bloomer WD, Goldenberg DM.

Int J Cancer. 2001 Nov;94(4):564-71.

27.

Tumor vasculature is targeted by the combination of combretastatin A-4 and hyperthermia.

Eikesdal HP, Bjerkvig R, Raleigh JA, Mella O, Dahl O.

Radiother Oncol. 2001 Dec;61(3):313-20.

PMID:
11731002
28.

Cyclosporin A causes a hypermetabolic state and hypoxia in the liver: prevention by dietary glycine.

Zhong Z, Li X, Yamashina S, von Frankenberg M, Enomoto N, Ikejima K, Kolinsky M, Raleigh JA, Thurman RG.

J Pharmacol Exp Ther. 2001 Dec;299(3):858-65.

PMID:
11714869
29.

Hypokalemia induces renal injury and alterations in vasoactive mediators that favor salt sensitivity.

Suga SI, Phillips MI, Ray PE, Raleigh JA, Vio CP, Kim YG, Mazzali M, Gordon KL, Hughes J, Johnson RJ.

Am J Physiol Renal Physiol. 2001 Oct;281(4):F620-9.

30.

Activated Kupffer cells cause a hypermetabolic state after gentle in situ manipulation of liver in rats.

Schemmer P, Enomoto N, Bradford BU, Bunzendahl H, Raleigh JA, Lemasters JJ, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2001 Jun;280(6):G1076-82.

31.

Autonomic nervous system and gut-derived endotoxin: involvement in activation of Kupffer cells after in situ organ manipulation.

Schemmer P, Enomoto N, Bradford BU, Bunzendahl H, Raleigh JA, Thurman RG.

World J Surg. 2001 Apr;25(4):399-406.

PMID:
11344388
32.

Invasive oxygen measurements and pimonidazole labeling in human cervix carcinoma.

Nordsmark M, Loncaster J, Chou SC, Havsteen H, Lindegaard JC, Davidson SE, Varia M, West C, Hunter R, Overgaard J, Raleigh JA.

Int J Radiat Oncol Biol Phys. 2001 Feb 1;49(2):581-6.

PMID:
11173158
33.

Semiquantitative immunohistochemical analysis for hypoxia in human tumors.

Raleigh JA, Chou SC, Bono EL, Thrall DE, Varia MA.

Int J Radiat Oncol Biol Phys. 2001 Feb 1;49(2):569-74.

PMID:
11173156
34.

Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development.

Lee YM, Jeong CH, Koo SY, Son MJ, Song HS, Bae SK, Raleigh JA, Chung HY, Yoo MA, Kim KW.

Dev Dyn. 2001 Feb;220(2):175-86.

35.

Changes in tumor hypoxia measured with a double hypoxic marker technique.

Ljungkvist AS, Bussink J, Rijken PF, Raleigh JA, Denekamp J, Van Der Kogel AJ.

Int J Radiat Oncol Biol Phys. 2000 Dec 1;48(5):1529-38.

PMID:
11121659
36.

Comparison between the comet assay and pimonidazole binding for measuring tumour hypoxia.

Olive PL, Durand RE, Raleigh JA, Luo C, Aquino-Parsons C.

Br J Cancer. 2000 Dec;83(11):1525-31.

37.

Spatial relationship between hypoxia and the (perfused) vascular network in a human glioma xenograft: a quantitative multi-parameter analysis.

Rijken PF, Bernsen HJ, Peters JP, Hodgkiss RJ, Raleigh JA, van der Kogel AJ.

Int J Radiat Oncol Biol Phys. 2000 Sep 1;48(2):571-82.

PMID:
10974478
38.

Hypoxia in a human intracerebral glioma model.

Bernsen HJ, Rijken PF, Peters H, Raleigh JA, Jeuken JW, Wesseling P, van der Kogel AJ.

J Neurosurg. 2000 Sep;93(3):449-54.

PMID:
10969943
39.

Vascular architecture and hypoxic profiles in human head and neck squamous cell carcinomas.

Wijffels KI, Kaanders JH, Rijken PF, Bussink J, van den Hoogen FJ, Marres HA, de Wilde PC, Raleigh JA, van der Kogel AJ.

Br J Cancer. 2000 Sep;83(5):674-83.

40.

Changes in blood perfusion and hypoxia after irradiation of a human squamous cell carcinoma xenograft tumor line.

Bussink J, Kaanders JH, Rijken PF, Raleigh JA, Van der Kogel AJ.

Radiat Res. 2000 Apr;153(4):398-404.

PMID:
10760999
41.

A clinical study of hypoxia and metallothionein protein expression in squamous cell carcinomas.

Raleigh JA, Chou SC, Calkins-Adams DP, Ballenger CA, Novotny DB, Varia MA.

Clin Cancer Res. 2000 Mar;6(3):855-62.

42.

Early wound healing exhibits cytokine surge without evidence of hypoxia.

Haroon ZA, Raleigh JA, Greenberg CS, Dewhirst MW.

Ann Surg. 2000 Jan;231(1):137-47.

43.

Gentle organ manipulation during harvest as a key determinant of survival of fatty livers after transplantation in the rat.

Schemmer P, Schoonhoven R, Swenberg JA, Bunzendahl H, Raleigh JA, Lemasters JJ, Thurman RG.

Transpl Int. 1999;12(5):351-9.

PMID:
10552001
44.

Osteocyte hypoxia: a novel mechanotransduction pathway.

Dodd JS, Raleigh JA, Gross TS.

Am J Physiol. 1999 Sep;277(3):C598-602. doi: 10.1152/ajpcell.1999.277.3.C598.

PMID:
10484347
45.

Mechanisms of alcohol-induced hepatotoxicity: studies in rats.

Thurman RG, Bradford BU, Iimuro Y, Frankenberg MV, Knecht KT, Connor HD, Adachi Y, Wall C, Arteel GE, Raleigh JA, Forman DT, Mason RP.

Front Biosci. 1999 Jul 15;4:e42-6. Review.

PMID:
10417060
46.

Binge drinking disturbs hepatic microcirculation after transplantation: prevention with free radical scavengers.

Zhong Z, Arteel GE, Connor HD, Schemmer P, Chou SC, Raleigh JA, Mason RP, Lemasters JJ, Thurman RG.

J Pharmacol Exp Ther. 1999 Aug;290(2):611-20.

PMID:
10411569
47.

Reperfusion injury in livers due to gentle in situ organ manipulation during harvest involves hypoxia and free radicals.

Schemmer P, Connor HD, Arteel GE, Raleigh JA, Bunzendahl H, Mason RP, Thurman RG.

J Pharmacol Exp Ther. 1999 Jul;290(1):235-40.

PMID:
10381781
48.

Graft survival is improved by hepatic denervation before organ harvesting.

Schemmer P, Bunzendahl H, Raleigh JA, Thurman RG.

Transplantation. 1999 May 27;67(10):1301-7.

PMID:
10360581
49.

Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors.

Raleigh JA, Chou SC, Arteel GE, Horsman MR.

Radiat Res. 1999 May;151(5):580-9.

PMID:
10319731
50.

Intravenous glycine improves survival in rat liver transplantation.

Schemmer P, Bradford BU, Rose ML, Bunzendahl H, Raleigh JA, Lemasters JJ, Thurman RG.

Am J Physiol. 1999 Apr;276(4):G924-32. doi: 10.1152/ajpgi.1999.276.4.G924.

PMID:
10198336

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