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Items: 37


Dietary wheat amylase trypsin inhibitors exacerbate murine allergic airway inflammation.

Zevallos VF, Raker VK, Maxeiner J, Scholtes P, Steinbrink K, Schuppan D.

Eur J Nutr. 2018 Mar 29. doi: 10.1007/s00394-018-1681-6. [Epub ahead of print]


Protein corona-mediated targeting of nanocarriers to B cells allows redirection of allergic immune responses.

Shen L, Tenzer S, Storck W, Hobernik D, Raker VK, Fischer K, Decker S, Dzionek A, Krauthäuser S, Diken M, Nikolaev A, Maxeiner J, Schuster P, Kappel C, Verschoor A, Schild H, Grabbe S, Bros M.

J Allergy Clin Immunol. 2018 Nov;142(5):1558-1570. doi: 10.1016/j.jaci.2017.08.049. Epub 2018 Jan 31.


Tolerance through Education: How Tolerogenic Dendritic Cells Shape Immunity.

Domogalla MP, Rostan PV, Raker VK, Steinbrink K.

Front Immunol. 2017 Dec 11;8:1764. doi: 10.3389/fimmu.2017.01764. eCollection 2017. Review.


Allergen-Specific Low Zone Tolerance Is Independent of MRP8/14-, TLR4-, TLR7-, and TLR9-Mediated Immune Processes.

Schmidt T, Lorenz N, Raker VK, Schmidgen MI, Mahnke K, Enk A, Roth J, Steinbrink K.

J Invest Dermatol. 2018 Feb;138(2):452-455. doi: 10.1016/j.jid.2017.09.020. Epub 2017 Sep 22. No abstract available.


Regulatory T cell deficient scurfy mice exhibit a Th2/M2-like inflammatory response in the skin.

Haeberle S, Raker V, Haub J, Kim YO, Weng SY, Yilmaz OK, Enk A, Steinbrink K, Schuppan D, Hadaschik EN.

J Dermatol Sci. 2017 Sep;87(3):285-291. doi: 10.1016/j.jdermsci.2017.07.001. Epub 2017 Jul 13.


Early inflammatory players in cutanous fibrosis.

Raker V, Haub J, Stojanovic A, Cerwenka A, Schuppan D, Steinbrink K.

J Dermatol Sci. 2017 Sep;87(3):228-235. doi: 10.1016/j.jdermsci.2017.06.009. Epub 2017 Jun 15. Review.


Nutritional Wheat Amylase-Trypsin Inhibitors Promote Intestinal Inflammation via Activation of Myeloid Cells.

Zevallos VF, Raker V, Tenzer S, Jimenez-Calvente C, Ashfaq-Khan M, Rüssel N, Pickert G, Schild H, Steinbrink K, Schuppan D.

Gastroenterology. 2017 Apr;152(5):1100-1113.e12. doi: 10.1053/j.gastro.2016.12.006. Epub 2016 Dec 16.


Myeloid cell populations and fibrogenic parameters in bleomycin- and HOCl-induced fibrosis.

Raker VK, Ook KY, Haub J, Lorenz N, Schmidt T, Stegemann A, Böhm M, Schuppan D, Steinbrink K.

Exp Dermatol. 2016 Nov;25(11):887-894. doi: 10.1111/exd.13124.


IL-10-Modulated Human Dendritic Cells for Clinical Use: Identification of a Stable and Migratory Subset with Improved Tolerogenic Activity.

Kryczanowsky F, Raker V, Graulich E, Domogalla MP, Steinbrink K.

J Immunol. 2016 Nov 1;197(9):3607-3617. Epub 2016 Sep 28.


Epicutaneous and Oral Low-Zone Tolerance Protects from Colitis in Mice.

Schmidt T, Lorenz N, Raker V, Reißig S, Waisman A, Weigmann B, Steinbrink K.

J Invest Dermatol. 2016 Sep;136(9):1831-9. doi: 10.1016/j.jid.2016.04.037. Epub 2016 May 17. Review.


The cAMP Pathway as Therapeutic Target in Autoimmune and Inflammatory Diseases.

Raker VK, Becker C, Steinbrink K.

Front Immunol. 2016 Mar 31;7:123. doi: 10.3389/fimmu.2016.00123. eCollection 2016. Review.


Tolerogenic Dendritic Cells for Regulatory T Cell Induction in Man.

Raker VK, Domogalla MP, Steinbrink K.

Front Immunol. 2015 Nov 9;6:569. doi: 10.3389/fimmu.2015.00569. eCollection 2015. Review.


Regulation of IgE production and airway reactivity by CD4⁻CD8⁻ regulatory T cells.

Raker V, Stein J, Montermann E, Maxeiner J, Taube C, Reske-Kunz AB, Sudowe S.

Immunobiology. 2015 Apr;220(4):490-9. doi: 10.1016/j.imbio.2014.10.022. Epub 2014 Oct 30.


Non-eosinophilic airway hyper-reactivity in mice, induced by IFN-γ producing CD4(+) and CD8(+) lung T cells, is responsive to steroid treatment.

Stein J, Maxeiner JH, Montermann E, Höhn Y, Raker V, Taube C, Sudowe S, Reske-Kunz AB.

Scand J Immunol. 2014 Nov;80(5):327-38. doi: 10.1111/sji.12217.


Research in practice: the impact of interferon-α therapy on immune tolerance.

Raker V, Steinbrink K.

J Dtsch Dermatol Ges. 2014 Apr;12(4):315-9. doi: 10.1111/ddg.12297. Epub 2014 Mar 14. Review.


Interferon-α suppresses cAMP to disarm human regulatory T cells.

Bacher N, Raker V, Hofmann C, Graulich E, Schwenk M, Baumgrass R, Bopp T, Zechner U, Merten L, Becker C, Steinbrink K.

Cancer Res. 2013 Sep 15;73(18):5647-56. doi: 10.1158/0008-5472.CAN-12-3788. Epub 2013 Jul 22.


Efficiency of biolistic DNA vaccination in experimental type I allergy.

Raker V, Maxeiner J, Reske-Kunz AB, Sudowe S.

Methods Mol Biol. 2013;940:357-70. doi: 10.1007/978-1-62703-110-3_26.


Strict 3' splice site sequence requirements for U2 snRNP recruitment after U2AF binding underlie a genetic defect leading to autoimmune disease.

Corrionero A, Raker VA, Izquierdo JM, Valcárcel J.

RNA. 2011 Mar;17(3):401-11. doi: 10.1261/rna.2444811. Epub 2011 Jan 13.


Antigen dose-dependent suppression of murine IgE responses is mediated by CD4(-)CD8(-) double-negative T cells.

Barwig C, Raker V, Montermann E, Grabbe S, Reske-Kunz AB, Sudowe S.

Clin Exp Allergy. 2010 Jun;40(6):891-901. doi: 10.1111/j.1365-2222.2010.03476.x. Epub 2010 Mar 1.


Modulation of alternative splicing by long-range RNA structures in Drosophila.

Raker VA, Mironov AA, Gelfand MS, Pervouchine DD.

Nucleic Acids Res. 2009 Aug;37(14):4533-44. doi: 10.1093/nar/gkp407. Epub 2009 May 22.


The methyl-CpG binding protein MBD1 is required for PML-RARalpha function.

Villa R, Morey L, Raker VA, Buschbeck M, Gutierrez A, De Santis F, Corsaro M, Varas F, Bossi D, Minucci S, Pelicci PG, Di Croce L.

Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1400-5. Epub 2006 Jan 23.


The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential.

Orsini F, Migliaccio E, Moroni M, Contursi C, Raker VA, Piccini D, Martin-Padura I, Pelliccia G, Trinei M, Bono M, Puri C, Tacchetti C, Ferrini M, Mannucci R, Nicoletti I, Lanfrancone L, Giorgio M, Pelicci PG.

J Biol Chem. 2004 Jun 11;279(24):25689-95. Epub 2004 Apr 12.


A cryptic targeting signal induces isoform-specific localization of p46Shc to mitochondria.

Ventura A, Maccarana M, Raker VA, Pelicci PG.

J Biol Chem. 2004 Jan 16;279(3):2299-306. Epub 2003 Oct 22.


A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

Trinei M, Giorgio M, Cicalese A, Barozzi S, Ventura A, Migliaccio E, Milia E, Padura IM, Raker VA, Maccarana M, Petronilli V, Minucci S, Bernardi P, Lanfrancone L, Pelicci PG.

Oncogene. 2002 May 30;21(24):3872-8.


Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor.

Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, Faretta M, Fuks F, Lo Coco F, Kouzarides T, Nervi C, Minucci S, Pelicci PG.

Science. 2002 Feb 8;295(5557):1079-82.


Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure.

Urlaub H, Raker VA, Kostka S, Lührmann R.

EMBO J. 2001 Jan 15;20(1-2):187-96.


Variations in normal color vision. II. Unique hues.

Webster MA, Miyahara E, Malkoc G, Raker VE.

J Opt Soc Am A Opt Image Sci Vis. 2000 Sep;17(9):1545-55.


Variations in normal color vision. I. Cone-opponent axes.

Webster MA, Miyahara E, Malkoc G, Raker VE.

J Opt Soc Am A Opt Image Sci Vis. 2000 Sep;17(9):1535-44.


Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy.

Bühler D, Raker V, Lührmann R, Fischer U.

Hum Mol Genet. 1999 Dec;8(13):2351-7.


Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs.

Kambach C, Walke S, Young R, Avis JM, de la Fortelle E, Raker VA, Lührmann R, Li J, Nagai K.

Cell. 1999 Feb 5;96(3):375-87.


An unusual chemical reactivity of Sm site adenosines strongly correlates with proper assembly of core U snRNP particles.

Hartmuth K, Raker VA, Huber J, Branlant C, Lührmann R.

J Mol Biol. 1999 Jan 8;285(1):133-47.


snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions.

Hermann H, Fabrizio P, Raker VA, Foulaki K, Hornig H, Brahms H, Lührmann R.

EMBO J. 1995 May 1;14(9):2076-88.


cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction.

Lehmeier T, Raker V, Hermann H, Lührmann R.

Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):12317-21.


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