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Items: 32

1.

Peptidoglycan associated cyclic lipopeptide disrupts viral infectivity.

Johnson BA, Hage A, Kalveram B, Mears M, Plante JA, Rodriguez SE, Ding Z, Luo X, Bente D, Bradrick SS, Freiberg AN, Popov V, Rajsbaum R, Rossi S, Russell WK, Menachery VD.

J Virol. 2019 Aug 28. pii: JVI.01282-19. doi: 10.1128/JVI.01282-19. [Epub ahead of print]

PMID:
31462558
2.

An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction.

Xia H, Luo H, Shan C, Muruato AE, Nunes BTD, Medeiros DBA, Zou J, Xie X, Giraldo MI, Vasconcelos PFC, Weaver SC, Wang T, Rajsbaum R, Shi PY.

Nat Commun. 2018 Jan 29;9(1):414. doi: 10.1038/s41467-017-02816-2.

3.

K48-linked polyubiquitination of dengue virus NS1 protein inhibits its interaction with the viral partner NS4B.

Giraldo MI, Vargas-Cuartas O, Gallego-Gomez JC, Shi PY, Padilla-Sanabria L, Castaño-Osorio JC, Rajsbaum R.

Virus Res. 2018 Feb 15;246:1-11. doi: 10.1016/j.virusres.2017.12.013. Epub 2017 Dec 30.

4.

The TRIMendous Role of TRIMs in Virus-Host Interactions.

van Tol S, Hage A, Giraldo MI, Bharaj P, Rajsbaum R.

Vaccines (Basel). 2017 Aug 22;5(3). pii: E23. doi: 10.3390/vaccines5030023. Review.

5.

The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication.

Bharaj P, Atkins C, Luthra P, Giraldo MI, Dawes BE, Miorin L, Johnson JR, Krogan NJ, Basler CF, Freiberg AN, Rajsbaum R.

J Virol. 2017 Aug 24;91(18). pii: e00833-17. doi: 10.1128/JVI.00833-17. Print 2017 Sep 15.

6.

Intranasal Delivery of Peptide-Morpholinos to Knockdown Influenza Host Factors in Mice.

Rajsbaum R.

Methods Mol Biol. 2017;1565:191-199. doi: 10.1007/978-1-4939-6817-6_16.

PMID:
28364244
7.

The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response.

Bharaj P, Wang YE, Dawes BE, Yun TE, Park A, Yen B, Basler CF, Freiberg AN, Lee B, Rajsbaum R.

PLoS Pathog. 2016 Sep 13;12(9):e1005880. doi: 10.1371/journal.ppat.1005880. eCollection 2016 Sep.

8.

Immune and non-immune responses to hepatitis C virus infection.

Sun J, Rajsbaum R, Yi M.

World J Gastroenterol. 2015 Oct 14;21(38):10739-48. doi: 10.3748/wjg.v21.i38.10739. Review.

9.

Virology. Unanchored ubiquitin in virus uncoating.

Rajsbaum R, García-Sastre A.

Science. 2014 Oct 24;346(6208):427-8. doi: 10.1126/science.1261509. No abstract available.

PMID:
25342790
10.

The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon.

Laurent-Rolle M, Morrison J, Rajsbaum R, Macleod JML, Pisanelli G, Pham A, Ayllon J, Miorin L, Martinez C, tenOever BR, García-Sastre A.

Cell Host Microbe. 2014 Sep 10;16(3):314-327. doi: 10.1016/j.chom.2014.07.015.

11.

InTRIMsic immunity: Positive and negative regulation of immune signaling by tripartite motif proteins.

Versteeg GA, Benke S, García-Sastre A, Rajsbaum R.

Cytokine Growth Factor Rev. 2014 Oct;25(5):563-76. doi: 10.1016/j.cytogfr.2014.08.001. Epub 2014 Aug 13. Review.

PMID:
25172371
12.

A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence.

Ayllon J, Domingues P, Rajsbaum R, Miorin L, Schmolke M, Hale BG, García-Sastre A.

J Virol. 2014 Oct;88(20):12146-51. doi: 10.1128/JVI.01567-14. Epub 2014 Jul 30.

13.

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.

Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Martínez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, García-Sastre A.

Immunity. 2014 Jun 19;40(6):880-95. doi: 10.1016/j.immuni.2014.04.018. Epub 2014 May 29.

14.

TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity.

Rajsbaum R, García-Sastre A, Versteeg GA.

J Mol Biol. 2014 Mar 20;426(6):1265-84. doi: 10.1016/j.jmb.2013.12.005. Epub 2013 Dec 12. Review.

15.

Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways.

Rajsbaum R, García-Sastre A.

Trends Microbiol. 2013 Aug;21(8):421-9. doi: 10.1016/j.tim.2013.06.006. Epub 2013 Jul 11. Review.

16.

TPL-2-ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I IFN production.

McNab FW, Ewbank J, Rajsbaum R, Stavropoulos E, Martirosyan A, Redford PS, Wu X, Graham CM, Saraiva M, Tsichlis P, Chaussabel D, Ley SC, O'Garra A.

J Immunol. 2013 Aug 15;191(4):1732-43. doi: 10.4049/jimmunol.1300146. Epub 2013 Jul 10.

17.

Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling.

Morrison J, Laurent-Rolle M, Maestre AM, Rajsbaum R, Pisanelli G, Simon V, Mulder LC, Fernandez-Sesma A, García-Sastre A.

PLoS Pathog. 2013 Mar;9(3):e1003265. doi: 10.1371/journal.ppat.1003265. Epub 2013 Mar 28.

18.

The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors.

Versteeg GA, Rajsbaum R, Sánchez-Aparicio MT, Maestre AM, Valdiviezo J, Shi M, Inn KS, Fernandez-Sesma A, Jung J, García-Sastre A.

Immunity. 2013 Feb 21;38(2):384-98. doi: 10.1016/j.immuni.2012.11.013.

19.

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.

Rajsbaum R, Albrecht RA, Wang MK, Maharaj NP, Versteeg GA, Nistal-Villán E, García-Sastre A, Gack MU.

PLoS Pathog. 2012;8(11):e1003059. doi: 10.1371/journal.ppat.1003059. Epub 2012 Nov 29.

20.

The transcription factor NFATp plays a key role in susceptibility to TB in mice.

Via LE, Tsytsykova AV, Rajsbaum R, Falvo JV, Goldfeld AE.

PLoS One. 2012;7(7):e41427. doi: 10.1371/journal.pone.0041427. Epub 2012 Jul 23.

21.

HERC6 is the main E3 ligase for global ISG15 conjugation in mouse cells.

Oudshoorn D, van Boheemen S, Sánchez-Aparicio MT, Rajsbaum R, García-Sastre A, Versteeg GA.

PLoS One. 2012;7(1):e29870. doi: 10.1371/journal.pone.0029870. Epub 2012 Jan 17.

22.

Tripartite-motif proteins and innate immune regulation.

McNab FW, Rajsbaum R, Stoye JP, O'Garra A.

Curr Opin Immunol. 2011 Feb;23(1):46-56. doi: 10.1016/j.coi.2010.10.021. Epub 2010 Dec 3. Review.

PMID:
21131187
23.

TPL-2 negatively regulates interferon-beta production in macrophages and myeloid dendritic cells.

Kaiser F, Cook D, Papoutsopoulou S, Rajsbaum R, Wu X, Yang HT, Grant S, Ricciardi-Castagnoli P, Tsichlis PN, Ley SC, O'Garra A.

J Exp Med. 2009 Aug 31;206(9):1863-71. doi: 10.1084/jem.20091059. Epub 2009 Aug 10.

24.

Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells.

Rajsbaum R, Stoye JP, O'Garra A.

Eur J Immunol. 2008 Mar;38(3):619-30. doi: 10.1002/eji.200737916.

25.

Activation-dependent intrachromosomal interactions formed by the TNF gene promoter and two distal enhancers.

Tsytsykova AV, Rajsbaum R, Falvo JV, Ligeiro F, Neely SR, Goldfeld AE.

Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16850-5. Epub 2007 Oct 16.

26.

NFAT5 regulates HIV-1 in primary monocytes via a highly conserved long terminal repeat site.

Ranjbar S, Tsytsykova AV, Lee SK, Rajsbaum R, Falvo JV, Lieberman J, Shankar P, Goldfeld AE.

PLoS Pathog. 2006 Dec;2(12):e130.

27.

Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.

Boonstra A, Rajsbaum R, Holman M, Marques R, Asselin-Paturel C, Pereira JP, Bates EE, Akira S, Vieira P, Liu YJ, Trinchieri G, O'Garra A.

J Immunol. 2006 Dec 1;177(11):7551-8.

29.

Linkage disequilibrium between HLA-DPB1 alleles and retinoid X receptor beta haplotypes.

Rajsbaum R, Fici D, Boggs DA, Fraser PA, Flores-Villanueva PO, Awdeh ZL.

Hum Immunol. 2002 Sep;63(9):771-8.

PMID:
12175732
30.

Evidence for coupling of membrane targeting and function of the signal recognition particle (SRP) receptor FtsY.

Herskovits AA, Seluanov A, Rajsbaum R, ten Hagen-Jongman CM, Henrichs T, Bochkareva ES, Phillips GJ, Probst FJ, Nakae T, Ehrmann M, Luirink J, Bibi E.

EMBO Rep. 2001 Nov;2(11):1040-6.

31.

Polymorphism of the human retinoid X receptor beta and linkage disequilibrium with HLA-DPB1.

Rajsbaum R, Fici D, Fraser PA, Flores-Villanueva PO, Awdeh ZL.

Tissue Antigens. 2001 Jul;58(1):24-9.

PMID:
11580852
32.

Molecular characterization of two genes encoding betaine aldehyde dehydrogenase from amaranth. Expression in leaves under short-term exposure to osmotic stress or abscisic acid.

Legaria J, Rajsbaum R, Muñoz-Clares RA, Villegas-Sepúlveda N, Simpson J, Iturriaga G.

Gene. 1998 Sep 18;218(1-2):69-76.

PMID:
9751804

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