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Items: 1 to 50 of 250

1.

Testicular cancer incidence predictions in Europe 2010-2035: A rising burden despite population ageing.

Znaor A, Skakkebaek NE, Rajpert-De Meyts E, Laversanne M, Kuliš T, Gurney J, Sarfati D, McGlynn KA, Bray F.

Int J Cancer. 2019 Nov 26. doi: 10.1002/ijc.32810. [Epub ahead of print]

PMID:
31773729
2.

Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes.

Harpelunde Poulsen K, Nielsen JE, Frederiksen H, Melau C, Juul Hare K, Langhoff Thuesen L, Perlman S, Lundvall L, Mitchell RT, Juul A, Rajpert-De Meyts E, Jørgensen A.

Hum Reprod. 2019 Nov 1;34(11):2228-2243. doi: 10.1093/humrep/dez191.

PMID:
31734698
3.

Characterisation and localisation of the endocannabinoid system components in the adult human testis.

Nielsen JE, Rolland AD, Rajpert-De Meyts E, Janfelt C, Jørgensen A, Winge SB, Kristensen DM, Juul A, Chalmel F, Jégou B, Skakkebaek NE.

Sci Rep. 2019 Sep 19;9(1):12866. doi: 10.1038/s41598-019-49177-y.

4.

Testicular germ cell cancer: recent developments in biology and clinical management.

Rajpert-De Meyts E.

Andrology. 2019 Jul;7(4):391-393. doi: 10.1111/andr.12675. No abstract available.

PMID:
31310059
5.

High-Throughput Sequencing-Based Investigation of Viruses in Human Cancers by Multienrichment Approach.

Mollerup S, Asplund M, Friis-Nielsen J, Kjartansdóttir KR, Fridholm H, Hansen TA, Herrera JAR, Barnes CJ, Jensen RH, Richter SR, Nielsen IB, Pietroni C, Alquezar-Planas DE, Rey-Iglesia A, Olsen PVS, Rajpert-De Meyts E, Groth-Pedersen L, von Buchwald C, Jensen DH, Gniadecki R, Høgdall E, Langhoff JL, Pete I, Vereczkey I, Baranyai Z, Dybkaer K, Johnsen HE, Steiniche T, Hokland P, Rosenberg J, Baandrup U, Sicheritz-Pontén T, Willerslev E, Brunak S, Lund O, Mourier T, Vinner L, Izarzugaza JMG, Nielsen LP, Hansen AJ.

J Infect Dis. 2019 Sep 13;220(8):1312-1324. doi: 10.1093/infdis/jiz318.

6.

European Academy of Andrology Newsletter (Edition December 2018).

Rajpert-De Meyts E, Krausz C.

Andrology. 2019 Jan;7(1):124-130. doi: 10.1111/andr.12582. No abstract available.

7.

Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis.

Jørgensen A, Macdonald J, Nielsen JE, Kilcoyne KR, Perlman S, Lundvall L, Langhoff Thuesen L, Juul Hare K, Frederiksen H, Andersson AM, Skakkebæk NE, Juul A, Sharpe RM, Rajpert-De Meyts E, Mitchell RT.

Cell Rep. 2018 Nov 13;25(7):1924-1937.e4. doi: 10.1016/j.celrep.2018.10.064.

8.

Expression of the O-Glycosylation Enzyme GalNAc-T3 in the Equatorial Segment Correlates with the Quality of Spermatozoa.

Nygaard MB, Herlihy AS, Jeanneau C, Nielsen JE, Bennett EP, Jørgensen N, Clausen H, Mandel U, Rajpert-De Meyts E, Almstrup K.

Int J Mol Sci. 2018 Sep 27;19(10). pii: E2949. doi: 10.3390/ijms19102949.

9.

Decrease in semen quality and Leydig cell function in infertile men: a longitudinal study.

Olesen IA, Joensen UN, Petersen JH, Almstrup K, Rajpert-De Meyts E, Carlsen E, McLachlan R, Juul A, Jørgensen N.

Hum Reprod. 2018 Nov 1;33(11):1963-1974. doi: 10.1093/humrep/dey283.

PMID:
30247578
10.

Quantification of the Leydig cell compartment in testicular biopsies and association with biochemical Leydig cell dysfunction in testicular cancer survivors.

Tarsitano MG, Bandak M, Jørgensen N, Skakkebaek NE, Juul A, Lenzi A, Daugaard G, Rajpert-De Meyts E.

Andrology. 2018 Sep;6(5):748-755. doi: 10.1111/andr.12508. Epub 2018 Jul 6.

11.

Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells.

Winge SB, Dalgaard MD, Belling KG, Jensen JM, Nielsen JE, Aksglaede L, Schierup MH, Brunak S, Skakkebæk NE, Juul A, Rajpert-De Meyts E, Almstrup K.

Cell Death Dis. 2018 May 22;9(6):586. doi: 10.1038/s41419-018-0671-1.

12.

Complex Polygenic Nature of Testicular Germ Cell Cancer Suggests Multifactorial Aetiology.

Rajpert-De Meyts E, Skotheim RI.

Eur Urol. 2018 Jun;73(6):832-833. doi: 10.1016/j.eururo.2018.02.023. Epub 2018 Mar 9. No abstract available.

PMID:
29530636
13.

Loss of Function of the Nuclear Receptor NR2F2, Encoding COUP-TF2, Causes Testis Development and Cardiac Defects in 46,XX Children.

Bashamboo A, Eozenou C, Jorgensen A, Bignon-Topalovic J, Siffroi JP, Hyon C, Tar A, Nagy P, Sólyom J, Halász Z, Paye-Jaouen A, Lambert S, Rodriguez-Buritica D, Bertalan R, Martinerie L, Rajpert-De Meyts E, Achermann JC, McElreavey K.

Am J Hum Genet. 2018 Mar 1;102(3):487-493. doi: 10.1016/j.ajhg.2018.01.021. Epub 2018 Feb 22.

14.

Deletion in the uridine diphosphate glucuronyltransferase 2B17 gene is associated with delayed pubarche in healthy boys.

Mouritsen A, Busch AS, Aksglaede L, Rajpert-De Meyts E, Juul A.

Endocr Connect. 2018 Mar;7(3):460-465. doi: 10.1530/EC-18-0080. Epub 2018 Feb 21.

15.

Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies.

Portnoi MF, Dumargne MC, Rojo S, Witchel SF, Duncan AJ, Eozenou C, Bignon-Topalovic J, Yatsenko SA, Rajkovic A, Reyes-Mugica M, Almstrup K, Fusee L, Srivastava Y, Chantot-Bastaraud S, Hyon C, Louis-Sylvestre C, Validire P, de Malleray Pichard C, Ravel C, Christin-Maitre S, Brauner R, Rossetti R, Persani L, Charreau EH, Dain L, Chiauzzi VA, Mazen I, Rouba H, Schluth-Bolard C, MacGowan S, McLean WHI, Patin E, Rajpert-De Meyts E, Jauch R, Achermann JC, Siffroi JP, McElreavey K, Bashamboo A.

Hum Mol Genet. 2018 Apr 1;27(7):1228-1240. doi: 10.1093/hmg/ddy037.

16.

Corrigendum to "Biglycan is a novel binding partner of fibroblast growth factor receptor 3c (FGFR3c) in the human testis" [Mol. Cell Endocrinol.] 399 (2015) 235-243.

Winge SB, Nielsen J, Jorgensen A, Owczarek S, Ewen KA, Nielsen JE, Juul A, Berezin V, Rajpert-De Meyts E.

Mol Cell Endocrinol. 2018 Jan 15;460:258. doi: 10.1016/j.mce.2017.12.001. No abstract available.

PMID:
29269121
17.

Polymorphisms in JMJD1C are associated with pubertal onset in boys and reproductive function in men.

Mørup N, Busch AS, Bang AK, Nordkap L, Nielsen JE, Rajpert-De Meyts E, Juul A, Jørgensen N, Almstrup K.

Sci Rep. 2017 Dec 8;7(1):17242. doi: 10.1038/s41598-017-17575-9.

18.

Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation.

Winge SB, Dalgaard MD, Jensen JM, Graem N, Schierup MH, Juul A, Rajpert-De Meyts E, Almstrup K.

Hum Mol Genet. 2018 Feb 1;27(3):430-439. doi: 10.1093/hmg/ddx411.

PMID:
29186436
19.

Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?

Bang AK, Busch AS, Almstrup K, Gromoll J, Kliesch S, Rajpert-De Meyts E, Skakkebaek NE, Juul A, Tüttelmann F, Jørgensen N.

Andrology. 2018 Jan;6(1):176-183. doi: 10.1111/andr.12440. Epub 2017 Nov 27.

20.

Germ Cell Neoplasia in Situ and Preserved Fertility Despite Suppressed Gonadotropins in a Patient With Testotoxicosis.

Juel Mortensen L, Blomberg Jensen M, Christiansen P, Rønholt AM, Jørgensen A, Frederiksen H, Nielsen JE, Loya AC, Grønkær Toft B, Skakkebæk NE, Rajpert-De Meyts E, Juul A.

J Clin Endocrinol Metab. 2017 Dec 1;102(12):4411-4416. doi: 10.1210/jc.2017-01761.

PMID:
29029242
21.

Possible involvement of the glucocorticoid receptor (NR3C1) and selected NR3C1 gene variants in regulation of human testicular function.

Nordkap L, Almstrup K, Nielsen JE, Bang AK, Priskorn L, Krause M, Holmboe SA, Winge SB, Egeberg Palme DL, Mørup N, Petersen JH, Juul A, Skakkebaek NE, Rajpert-De Meyts E, Jørgensen N.

Andrology. 2017 Nov;5(6):1105-1114. doi: 10.1111/andr.12418. Epub 2017 Oct 9.

22.

Factor V Leiden is associated with increased sperm count.

van Mens TE, Joensen UN, Bochdanovits Z, Takizawa A, Peter J, Jørgensen N, Szecsi PB, Meijers JCM, Weiler H, Rajpert-De Meyts E, Repping S, Middeldorp S.

Hum Reprod. 2017 Nov 1;32(11):2332-2339. doi: 10.1093/humrep/dex287.

PMID:
28927238
23.

Short stature homeobox-containing gene duplications in 3.7% of girls with tall stature and normal karyotypes.

Upners EN, Jensen RB, Rajpert-De Meyts E, Dunø M, Aksglaede L, Juul A.

Acta Paediatr. 2017 Oct;106(10):1651-1657. doi: 10.1111/apa.13969. Epub 2017 Jul 20.

PMID:
28667773
24.

Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor.

Wang Z, McGlynn KA, Rajpert-De Meyts E, Bishop DT, Chung CC, Dalgaard MD, Greene MH, Gupta R, Grotmol T, Haugen TB, Karlsson R, Litchfield K, Mitra N, Nielsen K, Pyle LC, Schwartz SM, Thorsson V, Vardhanabhuti S, Wiklund F, Turnbull C, Chanock SJ, Kanetsky PA, Nathanson KL; Testicular Cancer Consortium.

Nat Genet. 2017 Jul;49(7):1141-1147. doi: 10.1038/ng.3879. Epub 2017 Jun 12.

25.

Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline.

Giannoulatou E, Maher GJ, Ding Z, Gillis AJM, Dorssers LCJ, Hoischen A, Rajpert-De Meyts E; WGS500 Consortium, McVean G, Wilkie AOM, Looijenga LHJ, Goriely A.

PLoS One. 2017 May 22;12(5):e0178169. doi: 10.1371/journal.pone.0178169. eCollection 2017.

26.

Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours.

Rudolph C, Melau C, Nielsen JE, Vile Jensen K, Liu D, Pena-Diaz J, Rajpert-De Meyts E, Rasmussen LJ, Jørgensen A.

Cell Oncol (Dordr). 2017 Aug;40(4):341-355. doi: 10.1007/s13402-017-0326-8. Epub 2017 May 23.

PMID:
28536927
27.

Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity.

Belling K, Russo F, Jensen AB, Dalgaard MD, Westergaard D, Rajpert-De Meyts E, Skakkebæk NE, Juul A, Brunak S.

Hum Mol Genet. 2017 Apr 1;26(7):1219-1229. doi: 10.1093/hmg/ddx014.

28.

Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents.

Lottrup G, Belling K, Leffers H, Nielsen JE, Dalgaard MD, Juul A, Skakkebæk NE, Brunak S, Rajpert-De Meyts E.

Mol Hum Reprod. 2017 May 1;23(5):339-354. doi: 10.1093/molehr/gax012.

PMID:
28333300
29.

Leydig cell clustering and Reinke crystal distribution in relation to hormonal function in adult patients with testicular dysgenesis syndrome (TDS) including cryptorchidism.

Soerensen RR, Johannsen TH, Skakkebaek NE, Rajpert-De Meyts E.

Hormones (Athens). 2016 Oct;15(4):518-526. doi: 10.14310/horm.2002.1708.

30.

Rewarding peer-review work: the Publons initiative.

Rajpert-De Meyts E, Losito S, Carrell DT.

Andrology. 2016 Nov;4(6):985-986. doi: 10.1111/andr.12301. No abstract available.

31.

Dynamic GnRH and hCG testing: establishment of new diagnostic reference levels.

Bang AK, Nordkap L, Almstrup K, Priskorn L, Petersen JH, Rajpert-De Meyts E, Andersson AM, Juul A, Jørgensen N.

Eur J Endocrinol. 2017 Apr;176(4):379-391. doi: 10.1530/EJE-16-0912. Epub 2017 Jan 11.

PMID:
28077499
32.

Differences in global DNA methylation of testicular seminoma are not associated with changes in histone modifications, clinical prognosis, BRAF mutations or gene expression.

Pedersen LH, Nielsen JE, Daugaard G, Hansen TV, Rajpert-De Meyts E, Almstrup K.

Cancer Genet. 2016 Nov;209(11):506-514. doi: 10.1016/j.cancergen.2016.10.003. Epub 2016 Oct 31.

PMID:
27886677
33.

Clinical, genetic, biochemical, and testicular biopsy findings among 1,213 men evaluated for infertility.

Olesen IA, Andersson AM, Aksglaede L, Skakkebaek NE, Rajpert-de Meyts E, Joergensen N, Juul A.

Fertil Steril. 2017 Jan;107(1):74-82.e7. doi: 10.1016/j.fertnstert.2016.09.015. Epub 2016 Oct 25.

PMID:
27793385
34.

Special issue on endocrine disruption and reproductive health.

Rajpert-De Meyts E, Carrell DT.

Andrology. 2016 Jul;4(4):555. doi: 10.1111/andr.12243. No abstract available.

35.

Polygenic susceptibility to testicular cancer: implications for personalised health care.

Litchfield K, Mitchell JS, Shipley J, Huddart R, Rajpert-De Meyts E, Skakkebæk NE, Houlston RS, Turnbull C.

Br J Cancer. 2016 Jun 14;114(12):e22. doi: 10.1038/bjc.2016.136. Epub 2016 May 26. No abstract available.

36.

Andrology Award 2015.

Rajpert-De Meyts E, Carrell DT.

Andrology. 2016 May;4(3):361-2. doi: 10.1111/andr.12207. No abstract available.

37.

Cellular correlates of selfish spermatogonial selection.

Maher GJ, Rajpert-De Meyts E, Goriely A, Wilkie AO.

Andrology. 2016 May;4(3):550-3. doi: 10.1111/andr.12185. Epub 2016 Apr 26. No abstract available.

38.

Germ cell neoplasia in situ (GCNIS): evolution of the current nomenclature for testicular pre-invasive germ cell malignancy.

Berney DM, Looijenga LH, Idrees M, Oosterhuis JW, Rajpert-De Meyts E, Ulbright TM, Skakkebaek NE.

Histopathology. 2016 Jul;69(1):7-10. doi: 10.1111/his.12958. Epub 2016 Apr 12. Review.

PMID:
26918959
39.

Testicular germ cell tumours.

Rajpert-De Meyts E, McGlynn KA, Okamoto K, Jewett MA, Bokemeyer C.

Lancet. 2016 Apr 23;387(10029):1762-74. doi: 10.1016/S0140-6736(15)00991-5. Epub 2015 Dec 3. Review.

PMID:
26651223
40.

Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility.

Skakkebaek NE, Rajpert-De Meyts E, Buck Louis GM, Toppari J, Andersson AM, Eisenberg ML, Jensen TK, Jørgensen N, Swan SH, Sapra KJ, Ziebe S, Priskorn L, Juul A.

Physiol Rev. 2016 Jan;96(1):55-97. doi: 10.1152/physrev.00017.2015. Review.

41.

Polygenic susceptibility to testicular cancer: implications for personalised health care.

Litchfield K, Mitchell JS, Shipley J, Huddart R, Rajpert-De Meyts E, Skakkebæk NE, Houlston RS, Turnbull C.

Br J Cancer. 2015 Nov 17;113(10):1512-8. doi: 10.1038/bjc.2015.334. Epub 2015 Oct 13. Erratum in: Br J Cancer. 2016 Jun 14;114(12):e22.

42.

Pathogenesis of germ cell neoplasia in testicular dysgenesis and disorders of sex development.

Jørgensen A, Lindhardt Johansen M, Juul A, Skakkebaek NE, Main KM, Rajpert-De Meyts E.

Semin Cell Dev Biol. 2015 Sep;45:124-37. doi: 10.1016/j.semcdb.2015.09.013. Epub 2015 Sep 26. Review.

PMID:
26410164
43.

Diagnostic markers for germ cell neoplasms: from placental-like alkaline phosphatase to micro-RNAs.

Rajpert-De Meyts E, Nielsen JE, Skakkebaek NE, Almstrup K.

Folia Histochem Cytobiol. 2015;53(3):177-88. doi: 10.5603/FHC.a2015.0020. Epub 2015 Aug 26. Review.

44.

Human 3β-hydroxysteroid dehydrogenase deficiency seems to affect fertility but may not harbor a tumor risk: lesson from an experiment of nature.

Burckhardt MA, Udhane SS, Marti N, Schnyder I, Tapia C, Nielsen JE, Mullis PE, Rajpert-De Meyts E, Flück CE.

Eur J Endocrinol. 2015 Nov;173(5):K1-K12. doi: 10.1530/EJE-15-0599. Epub 2015 Aug 19. Review.

PMID:
26290012
45.

Ex vivo culture of human fetal gonads: manipulation of meiosis signalling by retinoic acid treatment disrupts testis development.

Jørgensen A, Nielsen JE, Perlman S, Lundvall L, Mitchell RT, Juul A, Rajpert-De Meyts E.

Hum Reprod. 2015 Oct;30(10):2351-63. doi: 10.1093/humrep/dev194. Epub 2015 Aug 6.

46.

Announcing the 2014 andrology award.

Carrell DT, Rajpert-De Meyts E.

Andrology. 2015 Mar;3(2):147. doi: 10.1111/andr.12039. No abstract available.

47.

Testicular Cancer Pathogenesis, Diagnosis and Endocrine Aspects.

Rajpert-De Meyts E, Skakkebaek NE, Toppari J.

In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.
2018 Jan 7.

48.

Contralateral biopsy in the management of testicular cancer: what we have learned and what we need to improve.

Rørth M, Grigor KM, Jørgensen N, Skakkebaek NE, Rajpert-De Meyts E.

Andrology. 2015 Jan;3(1):99-101. doi: 10.1111/andr.12008. No abstract available.

49.

Increasing international efforts to understand and conquer testicular germ cell cancer.

Rajpert-De Meyts E, Daugaard G, Almstrup K, Jørgensen A, Rørth M, Jørgensen N, von der Maase H, Skakkebaek NE.

Andrology. 2015 Jan;3(1):1-3. doi: 10.1111/andr.12010. No abstract available.

50.

Abundance of DLK1, differential expression of CYP11B1, CYP21A2 and MC2R, and lack of INSL3 distinguish testicular adrenal rest tumours from Leydig cell tumours.

Lottrup G, Nielsen JE, Skakkebæk NE, Juul A, Rajpert-De Meyts E.

Eur J Endocrinol. 2015 Apr;172(4):491-9. doi: 10.1530/EJE-14-0810. Epub 2015 Jan 21.

PMID:
25609776

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