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Items: 26


Increased arrhythmia susceptibility in type 2 diabetic mice related to dysregulation of ventricular sympathetic innervation.

Jungen C, Scherschel K, Flenner F, Jee H, Rajendran PS, De Jong KA, Nikolaev VO, Meyer C, Ardell JL, Tompkins JD.

Am J Physiol Heart Circ Physiol. 2019 Oct 18. doi: 10.1152/ajpheart.00249.2019. [Epub ahead of print]


Neuromodulation for Ventricular Tachycardia and Atrial Fibrillation: A Clinical Scenario-Based Review.

Zhu C, Hanna P, Rajendran PS, Shivkumar K.

JACC Clin Electrophysiol. 2019 Aug;5(8):881-896. doi: 10.1016/j.jacep.2019.06.009. Epub 2019 Aug 19. Review.


Publisher Correction: Systemic AAV vectors for widespread and targeted gene delivery in rodents.

Challis RC, Kumar SR, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V.

Nat Protoc. 2019 Aug;14(8):2597. doi: 10.1038/s41596-019-0155-5.


Anesthetizing the Fibrillating Heart.

Hanna P, Zhu C, Rajendran PS, Shivkumar K.

J Am Heart Assoc. 2019 May 21;8(10):e012713. doi: 10.1161/JAHA.119.012713.


Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies.

Rajendran PS, Challis RC, Fowlkes CC, Hanna P, Tompkins JD, Jordan MC, Hiyari S, Gabris-Weber BA, Greenbaum A, Chan KY, Deverman BE, Münzberg H, Ardell JL, Salama G, Gradinaru V, Shivkumar K.

Nat Commun. 2019 Apr 26;10(1):1944. doi: 10.1038/s41467-019-09770-1.


Neuroinflammation as a mechanism for cardiovascular diseases.

Rajendran PS, Hanna P, Zhu C, Shivkumar K.

Int J Cardiol. 2019 Aug 1;288:128-129. doi: 10.1016/j.ijcard.2019.04.003. Epub 2019 Apr 4. No abstract available.


Premature ventricular contraction diurnal profiles predict distinct clinical characteristics and beta-blocker responses.

Hamon D, Swid MA, Rajendran PS, Liu A, Boyle NG, Shivkumar K, Bradfield JS.

J Cardiovasc Electrophysiol. 2019 Jun;30(6):836-843. doi: 10.1111/jce.13944. Epub 2019 Apr 16.


Systemic AAV vectors for widespread and targeted gene delivery in rodents.

Challis RC, Ravindra Kumar S, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V.

Nat Protoc. 2019 Feb;14(2):379-414. doi: 10.1038/s41596-018-0097-3. Erratum in: Nat Protoc. 2019 Aug;14(8):2597.


Neural ablation to treat ventricular arrhythmias.

Hanna P, Rajendran PS, Shivkumar K.

Europace. 2018 Dec 1;20(12):1880-1881. doi: 10.1093/europace/euy134. No abstract available.


Antiarrhythmic effects of vagal nerve stimulation after cardiac sympathetic denervation in the setting of chronic myocardial infarction.

Yamaguchi N, Yamakawa K, Rajendran PS, Takamiya T, Vaseghi M.

Heart Rhythm. 2018 Aug;15(8):1214-1222. doi: 10.1016/j.hrthm.2018.03.012. Epub 2018 Mar 9.


Cardiac vanilloid receptor-1 afferent depletion enhances stellate ganglion neuronal activity and efferent sympathetic response to cardiac stress.

Yoshie K, Rajendran PS, Massoud L, Kwon O, Tadimeti V, Salavatian S, Ardell JL, Shivkumar K, Ajijola OA.

Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H954-H966. doi: 10.1152/ajpheart.00593.2017. Epub 2018 Jan 16.


Parasympathetic dysfunction and antiarrhythmic effect of vagal nerve stimulation following myocardial infarction.

Vaseghi M, Salavatian S, Rajendran PS, Yagishita D, Woodward WR, Hamon D, Yamakawa K, Irie T, Habecker BA, Shivkumar K.

JCI Insight. 2017 Aug 17;2(16). pii: 86715. doi: 10.1172/jci.insight.86715. eCollection 2017 Aug 17.


Cardiac neuroanatomy - Imaging nerves to define functional control.

Hanna P, Rajendran PS, Ajijola OA, Vaseghi M, Andrew Armour J, Ardell JL, Shivkumar K.

Auton Neurosci. 2017 Nov;207:48-58. doi: 10.1016/j.autneu.2017.07.008. Epub 2017 Jul 29. Review.


Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence.

Chai H, Diaz-Castro B, Shigetomi E, Monte E, Octeau JC, Yu X, Cohn W, Rajendran PS, Vondriska TM, Whitelegge JP, Coppola G, Khakh BS.

Neuron. 2017 Aug 2;95(3):531-549.e9. doi: 10.1016/j.neuron.2017.06.029. Epub 2017 Jul 14.


Bioelectronic block of paravertebral sympathetic nerves mitigates post-myocardial infarction ventricular arrhythmias.

Chui RW, Buckley U, Rajendran PS, Vrabec T, Shivkumar K, Ardell JL.

Heart Rhythm. 2017 Nov;14(11):1665-1672. doi: 10.1016/j.hrthm.2017.06.025. Epub 2017 Jun 16.


Premature Ventricular Contraction Coupling Interval Variability Destabilizes Cardiac Neuronal and Electrophysiological Control: Insights From Simultaneous Cardioneural Mapping.

Hamon D, Rajendran PS, Chui RW, Ajijola OA, Irie T, Talebi R, Salavatian S, Vaseghi M, Bradfield JS, Armour JA, Ardell JL, Shivkumar K.

Circ Arrhythm Electrophysiol. 2017 Apr;10(4). pii: e004937. doi: 10.1161/CIRCEP.116.004937.


Bioelectronic neuromodulation of the paravertebral cardiac efferent sympathetic outflow and its effect on ventricular electrical indices.

Buckley U, Chui RW, Rajendran PS, Vrabec T, Shivkumar K, Ardell JL.

Heart Rhythm. 2017 Jul;14(7):1063-1070. doi: 10.1016/j.hrthm.2017.02.020. Epub 2017 Feb 20.


Ganglionated plexus ablation for atrial fibrillation: Just because we can, does that mean we should?

Buckley U, Rajendran PS, Shivkumar K.

Heart Rhythm. 2017 Jan;14(1):133-134. doi: 10.1016/j.hrthm.2016.09.001. No abstract available.


CDX2 as a Prognostic Biomarker in Stage II and Stage III Colon Cancer.

Dalerba P, Sahoo D, Paik S, Guo X, Yothers G, Song N, Wilcox-Fogel N, Forgó E, Rajendran PS, Miranda SP, Hisamori S, Hutchison J, Kalisky T, Qian D, Wolmark N, Fisher GA, van de Rijn M, Clarke MF.

N Engl J Med. 2016 Jan 21;374(3):211-22. doi: 10.1056/NEJMoa1506597.


Myocardial infarction induces structural and functional remodelling of the intrinsic cardiac nervous system.

Rajendran PS, Nakamura K, Ajijola OA, Vaseghi M, Armour JA, Ardell JL, Shivkumar K.

J Physiol. 2016 Jan 15;594(2):321-41. doi: 10.1113/JP271165. Epub 2015 Dec 15.


Vagal nerve stimulation activates vagal afferent fibers that reduce cardiac efferent parasympathetic effects.

Yamakawa K, Rajendran PS, Takamiya T, Yagishita D, So EL, Mahajan A, Shivkumar K, Vaseghi M.

Am J Physiol Heart Circ Physiol. 2015 Nov;309(9):H1579-90. doi: 10.1152/ajpheart.00558.2015. Epub 2015 Sep 14.


Central-peripheral neural network interactions evoked by vagus nerve stimulation: functional consequences on control of cardiac function.

Ardell JL, Rajendran PS, Nier HA, KenKnight BH, Armour JA.

Am J Physiol Heart Circ Physiol. 2015 Nov 15;309(10):H1740-52. doi: 10.1152/ajpheart.00557.2015. Epub 2015 Sep 14.


Sympathetic nerve stimulation, not circulating norepinephrine, modulates T-peak to T-end interval by increasing global dispersion of repolarization.

Yagishita D, Chui RW, Yamakawa K, Rajendran PS, Ajijola OA, Nakamura K, So EL, Mahajan A, Shivkumar K, Vaseghi M.

Circ Arrhythm Electrophysiol. 2015 Feb;8(1):174-85. doi: 10.1161/CIRCEP.114.002195. Epub 2014 Dec 22.


Electrophysiological effects of right and left vagal nerve stimulation on the ventricular myocardium.

Yamakawa K, So EL, Rajendran PS, Hoang JD, Makkar N, Mahajan A, Shivkumar K, Vaseghi M.

Am J Physiol Heart Circ Physiol. 2014 Sep 1;307(5):H722-31. doi: 10.1152/ajpheart.00279.2014. Epub 2014 Jul 11.


Marshaling the autonomic nervous system for treatment of atrial fibrillation.

Rajendran PS, Buch E, Shivkumar K.

J Am Coll Cardiol. 2014 May 13;63(18):1902-3. doi: 10.1016/j.jacc.2014.01.033. Epub 2014 Feb 19. No abstract available.


Single-cell dissection of transcriptional heterogeneity in human colon tumors.

Dalerba P, Kalisky T, Sahoo D, Rajendran PS, Rothenberg ME, Leyrat AA, Sim S, Okamoto J, Johnston DM, Qian D, Zabala M, Bueno J, Neff NF, Wang J, Shelton AA, Visser B, Hisamori S, Shimono Y, van de Wetering M, Clevers H, Clarke MF, Quake SR.

Nat Biotechnol. 2011 Nov 13;29(12):1120-7. doi: 10.1038/nbt.2038.

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