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Items: 16

1.

A new class of synthetic retinoid antibiotics effective against bacterial persisters.

Kim W, Zhu W, Hendricks GL, Van Tyne D, Steele AD, Keohane CE, Fricke N, Conery AL, Shen S, Pan W, Lee K, Rajamuthiah R, Fuchs BB, Vlahovska PM, Wuest WM, Gilmore MS, Gao H, Ausubel FM, Mylonakis E.

Nature. 2018 Apr 5;556(7699):103-107. doi: 10.1038/nature26157. Epub 2018 Mar 28.

2.

Activity of a novel protonophore against methicillin-resistant Staphylococcus aureus.

Tharmalingam N, Jayamani E, Rajamuthiah R, Castillo D, Fuchs BB, Kelso MJ, Mylonakis E.

Future Med Chem. 2017 Aug;9(12):1401-1411. doi: 10.4155/fmc-2017-0047. Epub 2017 Aug 3.

3.

Characterization of a Francisella tularensis-Caenorhabditis elegans Pathosystem for the Evaluation of Therapeutic Compounds.

Jayamani E, Tharmalingam N, Rajamuthiah R, Coleman JJ, Kim W, Okoli I, Hernandez AM, Lee K, Nau GJ, Ausubel FM, Mylonakis E.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00310-17. doi: 10.1128/AAC.00310-17. Print 2017 Sep.

4.

NH125 kills methicillin-resistant Staphylococcus aureus persisters by lipid bilayer disruption.

Kim W, Fricke N, Conery AL, Fuchs BB, Rajamuthiah R, Jayamani E, Vlahovska PM, Ausubel FM, Mylonakis E.

Future Med Chem. 2016;8(3):257-69. doi: 10.4155/fmc.15.189. Epub 2016 Feb 24.

5.

Inhibition of bacterial and fungal pathogens by the orphaned drug auranofin.

Fuchs BB, RajaMuthiah R, Souza AC, Eatemadpour S, Rossoni RD, Santos DA, Junqueira JC, Rice LB, Mylonakis E.

Future Med Chem. 2016;8(2):117-32. doi: 10.4155/fmc.15.182. Epub 2016 Jan 25.

6.

On the Mechanism of Berberine-INF55 (5-Nitro-2-phenylindole) Hybrid Antibacterials.

Dolla NK, Chen C, Larkins-Ford J, Rajamuthiah R, Jagadeesan S, Conery AL, Ausubel FM, Mylonakis E, Bremner JB, Lewis K, Kelso MJ.

Aust J Chem. 2015;67:1471-1480.

7.

Erratum to: Micafungin Elicits an Immunomodulatory Effect in Galleria mellonella and Mice.

Fuchs BB, Li Y, Li D, Johnston T, Hendricks G, Li G, Rajamuthiah R, Mylonakis E.

Mycopathologia. 2016 Feb;181(1-2):27. doi: 10.1007/s11046-015-9959-1. No abstract available.

8.

Antibacterial properties of 3-(phenylsulfonyl)-2-pyrazinecarbonitrile.

Rajamuthiah R, Jayamani E, Majed H, Conery AL, Kim W, Kwon B, Fuchs BB, Kelso MJ, Ausubel FM, Mylonakis E.

Bioorg Med Chem Lett. 2015 Nov 15;25(22):5203-7. doi: 10.1016/j.bmcl.2015.09.066. Epub 2015 Sep 30.

9.

Micafungin Elicits an Immunomodulatory Effect in Galleria mellonella and Mice.

Fuchs BB, Li Y, Li D, Johnston T, Hendricks G, Li G, Rajamuthiah R, Mylonakis E.

Mycopathologia. 2016 Feb;181(1-2):17-25. doi: 10.1007/s11046-015-9940-z. Epub 2015 Sep 18. Erratum in: Mycopathologia. 2016 Feb;181(1-2):27.

10.

A Defensin from the Model Beetle Tribolium castaneum Acts Synergistically with Telavancin and Daptomycin against Multidrug Resistant Staphylococcus aureus.

Rajamuthiah R, Jayamani E, Conery AL, Fuchs BB, Kim W, Johnston T, Vilcinskas A, Ausubel FM, Mylonakis E.

PLoS One. 2015 Jun 10;10(6):e0128576. doi: 10.1371/journal.pone.0128576. eCollection 2015.

11.

Identification of an Antimicrobial Agent Effective against Methicillin-Resistant Staphylococcus aureus Persisters Using a Fluorescence-Based Screening Strategy.

Kim W, Conery AL, Rajamuthiah R, Fuchs BB, Ausubel FM, Mylonakis E.

PLoS One. 2015 Jun 3;10(6):e0127640. doi: 10.1371/journal.pone.0127640. eCollection 2015.

12.

Repurposing salicylanilide anthelmintic drugs to combat drug resistant Staphylococcus aureus.

Rajamuthiah R, Fuchs BB, Conery AL, Kim W, Jayamani E, Kwon B, Ausubel FM, Mylonakis E.

PLoS One. 2015 Apr 21;10(4):e0124595. doi: 10.1371/journal.pone.0124595. eCollection 2015.

13.

Insect-derived cecropins display activity against Acinetobacter baumannii in a whole-animal high-throughput Caenorhabditis elegans model.

Jayamani E, Rajamuthiah R, Larkins-Ford J, Fuchs BB, Conery AL, Vilcinskas A, Ausubel FM, Mylonakis E.

Antimicrob Agents Chemother. 2015 Mar;59(3):1728-37. doi: 10.1128/AAC.04198-14. Epub 2015 Jan 12.

14.

Effector triggered immunity.

Rajamuthiah R, Mylonakis E.

Virulence. 2014;5(7):697-702. doi: 10.4161/viru.29091. Review.

15.

A multi-host approach for the systematic analysis of virulence factors in Cryptococcus neoformans.

Desalermos A, Tan X, Rajamuthiah R, Arvanitis M, Wang Y, Li D, Kourkoumpetis TK, Fuchs BB, Mylonakis E.

J Infect Dis. 2015 Jan 15;211(2):298-305. doi: 10.1093/infdis/jiu441. Epub 2014 Aug 11.

16.

Whole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureus.

Rajamuthiah R, Fuchs BB, Jayamani E, Kim Y, Larkins-Ford J, Conery A, Ausubel FM, Mylonakis E.

PLoS One. 2014 Feb 19;9(2):e89189. doi: 10.1371/journal.pone.0089189. eCollection 2014.

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