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Items: 13


An update on the safety of current therapies for Alzheimer's disease: focus on rivastigmine.

Khoury R, Rajamanickam J, Grossberg GT.

Ther Adv Drug Saf. 2018 Mar;9(3):171-178. doi: 10.1177/2042098617750555. Epub 2018 Jan 8. Review.


Akt-mediated regulation of antidepressant-sensitive serotonin transporter function, cell-surface expression and phosphorylation.

Rajamanickam J, Annamalai B, Rahbek-Clemmensen T, Sundaramurthy S, Gether U, Jayanthi LD, Ramamoorthy S.

Biochem J. 2015 May 15;468(1):177-90. doi: 10.1042/BJ20140826.


Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1/2-dependent mechanism.

Kivell B, Uzelac Z, Sundaramurthy S, Rajamanickam J, Ewald A, Chefer V, Jaligam V, Bolan E, Simonson B, Annamalai B, Mannangatti P, Prisinzano TE, Gomes I, Devi LA, Jayanthi LD, Sitte HH, Ramamoorthy S, Shippenberg TS.

Neuropharmacology. 2014 Nov;86:228-40. doi: 10.1016/j.neuropharm.2014.07.016. Epub 2014 Aug 10.


Bioavailability through PepT1: the role of computer modelling in intelligent drug design.

Foley DW, Rajamanickam J, Bailey PD, Meredith D.

Curr Comput Aided Drug Des. 2010 Mar;6(1):68-78. Review.


EAAT4 phosphorylation at the SGK1 consensus site is required for transport modulation by the kinase.

Rajamanickam J, Palmada M, Lang F, Boehmer C.

J Neurochem. 2007 Aug;102(3):858-66. Epub 2007 Apr 17.


Upregulation of HERG channels by the serum and glucocorticoid inducible kinase isoform SGK3.

Maier G, Palmada M, Rajamanickam J, Shumilina E, Böhmer C, Lang F.

Cell Physiol Biochem. 2006;18(4-5):177-86.


Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet.

Huang DY, Boini KM, Osswald H, Friedrich B, Artunc F, Ullrich S, Rajamanickam J, Palmada M, Wulff P, Kuhl D, Vallon V, Lang F.

Am J Physiol Renal Physiol. 2006 Dec;291(6):F1264-73. Epub 2006 Sep 26.


Post-translational regulation of EAAT2 function by co-expressed ubiquitin ligase Nedd4-2 is impacted by SGK kinases.

Boehmer C, Palmada M, Rajamanickam J, Schniepp R, Amara S, Lang F.

J Neurochem. 2006 May;97(4):911-21. Epub 2006 Mar 29.


SGK1 kinase upregulates GLUT1 activity and plasma membrane expression.

Palmada M, Boehmer C, Akel A, Rajamanickam J, Jeyaraj S, Keller K, Lang F.

Diabetes. 2006 Feb;55(2):421-7.


Regulation of the excitatory amino acid transporter EAAT5 by the serum and glucocorticoid dependent kinases SGK1 and SGK3.

Boehmer C, Rajamanickam J, Schniepp R, Kohler K, Wulff P, Kuhl D, Palmada M, Lang F.

Biochem Biophys Res Commun. 2005 Apr 8;329(2):738-42.


Stimulation of the EAAT4 glutamate transporter by SGK protein kinase isoforms and PKB.

Böhmer C, Philippin M, Rajamanickam J, Mack A, Broer S, Palmada M, Lang F.

Biochem Biophys Res Commun. 2004 Nov 26;324(4):1242-8.


Regulation of CLC-Ka/barttin by the ubiquitin ligase Nedd4-2 and the serum- and glucocorticoid-dependent kinases.

Embark HM, Böhmer C, Palmada M, Rajamanickam J, Wyatt AW, Wallisch S, Capasso G, Waldegger P, Seyberth HW, Waldegger S, Lang F.

Kidney Int. 2004 Nov;66(5):1918-25.


Regulation of glucose transporter SGLT1 by ubiquitin ligase Nedd4-2 and kinases SGK1, SGK3, and PKB.

Dieter M, Palmada M, Rajamanickam J, Aydin A, Busjahn A, Boehmer C, Luft FC, Lang F.

Obes Res. 2004 May;12(5):862-70.

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