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Items: 1 to 50 of 164

1.

The potassium channel Kcne3 is a VEGFA-inducible gene selectively expressed by vascular endothelial tip cells.

Deckelbaum RA, Lobov IB, Cheung E, Halasz G, Rajamani S, Lerner J, Tong C, Li Z, Boland P, Dominguez M, Hughes V, Yancopoulos GD, Murphy AJ, Thurston G, Cao J, Romano C, Gale NW.

Angiogenesis. 2019 Nov 21. doi: 10.1007/s10456-019-09696-8. [Epub ahead of print]

PMID:
31754927
2.

Lipid-Assisted Polymerization of Nucleotides.

Olasagasti F, Rajamani S.

Life (Basel). 2019 Nov 5;9(4). pii: E83. doi: 10.3390/life9040083. Review.

3.

Sequence variants with large effects on cardiac electrophysiology and disease.

Norland K, Sveinbjornsson G, Thorolfsdottir RB, Davidsson OB, Tragante V, Rajamani S, Helgadottir A, Gretarsdottir S, van Setten J, Asselbergs FW, Sverrisson JT, Stephensen SS, Oskarsson G, Sigurdsson EL, Andersen K, Danielsen R, Thorgeirsson G, Thorsteinsdottir U, Arnar DO, Sulem P, Holm H, Gudbjartsson DF, Stefansson K.

Nat Commun. 2019 Oct 22;10(1):4803. doi: 10.1038/s41467-019-12682-9.

4.

Mechanisms by Which Ranolazine Terminates Paroxysmal but Not Persistent Atrial Fibrillation.

Ramirez RJ, Takemoto Y, Martins RP, Filgueiras-Rama D, Ennis SR, Mironov S, Bhushal S, Deo M, Rajamani S, Berenfeld O, Belardinelli L, Jalife J, Pandit SV.

Circ Arrhythm Electrophysiol. 2019 Oct;12(10):e005557. doi: 10.1161/CIRCEP.117.005557. Epub 2019 Oct 9.

PMID:
31594392
5.

Interaction of the mononucleotide UMP with a fluid phospholipid bilayer.

Sasidharan S, Pochinda S, Elgaard-Jørgensen PN, Rajamani S, Khandelia H, Raghunathan VA.

Soft Matter. 2019 Oct 28;15(40):8129-8136. doi: 10.1039/c9sm01257e. Epub 2019 Oct 7.

PMID:
31589218
6.

Formation of Abasic Oligomers in Nonenzymatic Polymerization of Canonical Nucleotides.

Mungi CV, Bapat NV, Hongo Y, Rajamani S.

Life (Basel). 2019 Jul 4;9(3). pii: E57. doi: 10.3390/life9030057.

7.

Analysis of the prognostic utility of the cell cycle progression (CCP) score generated from needle biopsy in men treated with definitive therapy.

Canter DJ, Freedland S, Rajamani S, Latsis M, Variano M, Halat S, Tward J, Cohen T, Stone S, Schlomm T, Bishoff J, Bardot S.

Prostate Cancer Prostatic Dis. 2019 Jun 27. doi: 10.1038/s41391-019-0159-9. [Epub ahead of print]

PMID:
31243337
8.

Enhancing the antibacterial activity of polymyxins using a nonantibiotic drug.

Krishnamurthy M, Lemmon MM, Falcinelli EM, Sandy RA, Dootz JN, Mott TM, Rajamani S, Schaecher KE, Duplantier AJ, Panchal RG.

Infect Drug Resist. 2019 May 27;12:1393-1405. doi: 10.2147/IDR.S196874. eCollection 2019.

9.

A high-performance hydrogen sensor based on a reverse-biased MoS2/GaN heterojunction.

Goel N, Kumar R, Jain SK, Rajamani S, Roul B, Gupta G, Kumar M, Krupanidhi SB.

Nanotechnology. 2019 Aug 2;30(31):314001. doi: 10.1088/1361-6528/ab1102. Epub 2019 Mar 19.

PMID:
30889560
10.

Novel regulation of the mammalian cardiac Na+ channel by dipeptidyl peptidase 10 interactions: An editorial comment.

Ni H, Rajamani S, Giles WR.

Int J Cardiol. 2019 Jun 1;284:74-76. doi: 10.1016/j.ijcard.2019.02.011. Epub 2019 Feb 13. No abstract available.

PMID:
30827732
11.

Robust biofilm assay for quantification and high throughput screening applications.

Rajamani S, Sandy R, Kota K, Lundh L, Gomba G, Recabo K, Duplantier A, Panchal RG.

J Microbiol Methods. 2019 Apr;159:179-185. doi: 10.1016/j.mimet.2019.02.018. Epub 2019 Feb 28.

PMID:
30826440
12.

Comparison of the Prognostic Utility of the Cell Cycle Progression Score for Predicting Clinical Outcomes in African American and Non-African American Men with Localized Prostate Cancer.

Canter DJ, Reid J, Latsis M, Variano M, Halat S, Rajamani S, Gurtner KE, Sangale Z, Brawer M, Stone S, Bardot S.

Eur Urol. 2019 Mar;75(3):515-522. doi: 10.1016/j.eururo.2018.10.028. Epub 2018 Oct 31.

13.

Evaluation of Data Exchange Process for Interoperability and Impact on Electronic Laboratory Reporting Quality to a State Public Health Agency.

Rajamani S, Kayser A, Emerson E, Solarz S.

Online J Public Health Inform. 2018 Sep 21;10(2):e204. doi: 10.5210/ojphi.v10i2.9317. eCollection 2018.

14.

Templated replication (or lack thereof) under prebiotically pertinent conditions.

Bapat NV, Rajamani S.

Sci Rep. 2018 Oct 9;8(1):15032. doi: 10.1038/s41598-018-33157-9.

15.

Deletion of Adam6 in Mus musculus leads to male subfertility and deficits in sperm ascent into the oviduct.

Voronina VA, Harris FM, Schmahl J, Galligan C, Oristian D, Zamfirova R, Gong G, Bai Y, Fury W, Rajamani S, Walls JR, Poueymirou WT, Esau L, Gale NW, Auerbach W, Murphy AJ, Macdonald LE.

Biol Reprod. 2019 Mar 1;100(3):686-696. doi: 10.1093/biolre/ioy210.

PMID:
30289441
16.

Coding variants in RPL3L and MYZAP increase risk of atrial fibrillation.

Thorolfsdottir RB, Sveinbjornsson G, Sulem P, Nielsen JB, Jonsson S, Halldorsson GH, Melsted P, Ivarsdottir EV, Davidsson OB, Kristjansson RP, Thorleifsson G, Helgadottir A, Gretarsdottir S, Norddahl G, Rajamani S, Torfason B, Valgardsson AS, Sverrisson JT, Tragante V, Holmen OL, Asselbergs FW, Roden DM, Darbar D, Pedersen TR, Sabatine MS, Willer CJ, Løchen ML, Halldorsson BV, Jonsdottir I, Hveem K, Arnar DO, Thorsteinsdottir U, Gudbjartsson DF, Holm H, Stefansson K.

Commun Biol. 2018 Jun 12;1:68. doi: 10.1038/s42003-018-0068-9. eCollection 2018.

17.

Bioengineering of bacterial pathogens for noninvasive imaging and in vivo evaluation of therapeutics.

Rajamani S, Kuszpit K, Scarff JM, Lundh L, Khan M, Brown J, Stafford R, Cazares LH, Panchal RG, Bocan T.

Sci Rep. 2018 Aug 22;8(1):12618. doi: 10.1038/s41598-018-30806-x.

18.

Correction: Synthesis of barbituric acid containing nucleotides and their implications for the origin of primitive informational polymers.

Mungi CV, Singh SK, Chugh J, Rajamani S.

Phys Chem Chem Phys. 2018 Aug 8;20(31):20734. doi: 10.1039/c8cp91818j.

PMID:
30043780
19.

Augmented anticancer activity of naringenin-loaded TPGS polymeric nanosuspension for drug resistive MCF-7 human breast cancer cells.

Rajamani S, Radhakrishnan A, Sengodan T, Thangavelu S.

Drug Dev Ind Pharm. 2018 Nov;44(11):1752-1761. doi: 10.1080/03639045.2018.1496445. Epub 2018 Aug 31.

PMID:
29968480
20.

Stakeholder Use and Feedback on Vaccination History and Clinical Decision Support for Immunizations Offered by Public Health.

Rajamani S, Bieringer A, Sowunmi S, Muscoplat M.

AMIA Annu Symp Proc. 2018 Apr 16;2017:1450-1457. eCollection 2017.

21.

Developing Workforce Capacity in Public Health Informatics: Core Competencies and Curriculum Design.

Wholey DR, LaVenture M, Rajamani S, Kreiger R, Hedberg C, Kenyon C.

Front Public Health. 2018 May 2;6:124. doi: 10.3389/fpubh.2018.00124. eCollection 2018.

22.

Enhanced late sodium current underlies pro-arrhythmic intracellular sodium and calcium dysregulation in murine sodium channelopathy.

Rivaud MR, Baartscheer A, Verkerk AO, Beekman L, Rajamani S, Belardinelli L, Bezzina CR, Remme CA.

Int J Cardiol. 2018 Jul 15;263:54-62. doi: 10.1016/j.ijcard.2018.03.044.

PMID:
29754923
23.

A common co-morbidity modulates disease expression and treatment efficacy in inherited cardiac sodium channelopathy.

Rivaud MR, Jansen JA, Postema PG, Nannenberg EA, Mizusawa Y, van der Nagel R, Wolswinkel R, van der Made I, Marchal GA, Rajamani S, Belardinelli L, van Tintelen JP, Tanck MWT, van der Wal AC, de Bakker JMT, van Rijen HV, Creemers EE, Wilde AAM, van den Berg MP, van Veen TAB, Bezzina CR, Remme CA.

Eur Heart J. 2018 Aug 14;39(31):2898-2907. doi: 10.1093/eurheartj/ehy247.

PMID:
29718149
24.

Deep UV narrow-band photodetector based on ion beam synthesized indium oxide quantum dots in Al2O3 matrix.

Rajamani S, Arora K, Konakov A, Belov A, Korolev D, Nikolskaya A, Mikhaylov A, Surodin S, Kryukov R, Nikolitchev D, Sushkov A, Pavlov D, Tetelbaum D, Kumar M, Kumar M.

Nanotechnology. 2018 Jul 27;29(30):305603. doi: 10.1088/1361-6528/aabfaf. Epub 2018 Apr 20.

PMID:
29676733
25.

Identification of men with low-risk biopsy-confirmed prostate cancer as candidates for active surveillance.

Lin DW, Crawford ED, Keane T, Evans B, Reid J, Rajamani S, Brown K, Gutin A, Tward J, Scardino P, Brawer M, Stone S, Cuzick J.

Urol Oncol. 2018 Jun;36(6):310.e7-310.e13. doi: 10.1016/j.urolonc.2018.03.011. Epub 2018 Apr 11.

PMID:
29655620
26.

Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia.

Bossu A, Houtman MJC, Meijborg VMF, Varkevisser R, Beekman HDM, Dunnink A, de Bakker JMT, Mollova N, Rajamani S, Belardinelli L, van der Heyden MAG, Vos MA.

Br J Pharmacol. 2018 Jun;175(12):2470-2482. doi: 10.1111/bph.14217. Epub 2018 May 6.

27.

Improved Sensitivity with Low Limit of Detection of a Hydrogen Gas Sensor Based on rGO-Loaded Ni-Doped ZnO Nanostructures.

Bhati VS, Ranwa S, Rajamani S, Kumari K, Raliya R, Biswas P, Kumar M.

ACS Appl Mater Interfaces. 2018 Apr 4;10(13):11116-11124. doi: 10.1021/acsami.7b17877. Epub 2018 Mar 23.

PMID:
29537250
28.

Assessing the Representation of Occupation Information in Free-Text Clinical Documents Across Multiple Sources.

Lindemann EA, Chen ES, Rajamani S, Manohar N, Wang Y, Melton GB.

Stud Health Technol Inform. 2017;245:486-490.

29.

Pro-arrhythmic effects of low plasma [K+] in human ventricle: An illustrated review.

Trenor B, Cardona K, Romero L, Gomez JF, Saiz J, Rajamani S, Belardinelli L, Giles W.

Trends Cardiovasc Med. 2018 May;28(4):233-242. doi: 10.1016/j.tcm.2017.11.002. Epub 2017 Nov 24. Review.

PMID:
29203397
30.

Formation and Stability of Prebiotically Relevant Vesicular Systems in Terrestrial Geothermal Environments.

Joshi MP, Samanta A, Tripathy GR, Rajamani S.

Life (Basel). 2017 Nov 30;7(4). pii: E51. doi: 10.3390/life7040051.

31.

Biosensors for the Detection and Quantification of AI-2 Class Quorum-Sensing Compounds.

Rajamani S, Sayre R.

Methods Mol Biol. 2018;1673:73-88. doi: 10.1007/978-1-4939-7309-5_6.

PMID:
29130165
32.

A Missense Variant in PLEC Increases Risk of Atrial Fibrillation.

Thorolfsdottir RB, Sveinbjornsson G, Sulem P, Helgadottir A, Gretarsdottir S, Benonisdottir S, Magnusdottir A, Davidsson OB, Rajamani S, Roden DM, Darbar D, Pedersen TR, Sabatine MS, Jonsdottir I, Arnar DO, Thorsteinsdottir U, Gudbjartsson DF, Holm H, Stefansson K.

J Am Coll Cardiol. 2017 Oct 24;70(17):2157-2168. doi: 10.1016/j.jacc.2017.09.005.

33.

Selective inhibition of physiological late Na+ current stabilizes ventricular repolarization.

El-Bizri N, Li CH, Liu GX, Rajamani S, Belardinelli L.

Am J Physiol Heart Circ Physiol. 2018 Feb 1;314(2):H236-H245. doi: 10.1152/ajpheart.00071.2017. Epub 2017 Sep 29.

34.

Analytical validation of a 12-gene molecular test for the prediction of distant recurrence in breast cancer.

Warf MB, Rajamani S, Krappmann K, Doedt J, Cassiano J, Brown K, Reid JE, Kronenwett R, Roa BB.

Future Sci OA. 2017 Jun 5;3(3):FSO221. doi: 10.4155/fsoa-2017-0051. eCollection 2017 Aug.

35.

The Expansion of Heterotopic Bone in Fibrodysplasia Ossificans Progressiva Is Activin A-Dependent.

Upadhyay J, Xie L, Huang L, Das N, Stewart RC, Lyon MC, Palmer K, Rajamani S, Graul C, Lobo M, Wellman TJ, Soares EJ, Silva MD, Hesterman J, Wang L, Wen X, Qian X, Nannuru K, Idone V, Murphy AJ, Economides AN, Hatsell SJ.

J Bone Miner Res. 2017 Dec;32(12):2489-2499. doi: 10.1002/jbmr.3235. Epub 2017 Sep 22.

36.

Efficient room temperature hydrogen sensor based on UV-activated ZnO nano-network.

Kumar M, Kumar R, Rajamani S, Ranwa S, Fanetti M, Valant M, Kumar M.

Nanotechnology. 2017 Sep 8;28(36):365502. doi: 10.1088/1361-6528/aa7cad. Epub 2017 Jun 30.

PMID:
28664873
37.

Immunization Information System and Informatics to Promote Immunizations: Perspective From Minnesota Immunization Information Connection.

Muscoplat MH, Rajamani S.

Biomed Inform Insights. 2017 Feb 9;9:1178222616688893. doi: 10.1177/1178222616688893. eCollection 2017.

38.

Representation of occupational information across resources and validation of the occupational data for health model.

Rajamani S, Chen ES, Lindemann E, Aldekhyyel R, Wang Y, Melton GB.

J Am Med Inform Assoc. 2018 Feb 1;25(2):197-205. doi: 10.1093/jamia/ocx035.

39.

Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 in murine Scn5a-1798insD+/- and human SCN5A-1795insD+/- iPSC-derived cardiomyocytes.

Portero V, Casini S, Hoekstra M, Verkerk AO, Mengarelli I, Belardinelli L, Rajamani S, Wilde AAM, Bezzina CR, Veldkamp MW, Remme CA.

Cardiovasc Res. 2017 Jun 1;113(7):829-838. doi: 10.1093/cvr/cvx077.

PMID:
28430892
40.

Content and Quality of Free-Text Occupation Documentation in the Electronic Health Record.

Aldekhyyel R, Chen ES, Rajamani S, Wang Y, Melton GB.

AMIA Annu Symp Proc. 2017 Feb 10;2016:1708-1716. eCollection 2016.

41.

Health Reform in Minnesota: An Analysis of Complementary Initiatives Implementing Electronic Health Record Technology and Care Coordination.

Soderberg K, Rajamani S, Wholey D, LaVenture M.

Online J Public Health Inform. 2016 Dec 28;8(3):e204. doi: 10.5210/ojphi.v8i3.7094. eCollection 2016.

42.

Direct and Electronic Health Record Access to the Clinical Decision Support for Immunizations in the Minnesota Immunization Information System.

Rajamani S, Bieringer A, Wallerius S, Jensen D, Winden T, Muscoplat MH.

Biomed Inform Insights. 2016 Dec 22;8(Suppl 2):23-29. doi: 10.4137/BII.S40208. eCollection 2016.

43.

Bacterial genome engineering and synthetic biology: combating pathogens.

Krishnamurthy M, Moore RT, Rajamani S, Panchal RG.

BMC Microbiol. 2016 Nov 4;16(1):258. Review.

44.

Eleclazine, an inhibitor of the cardiac late sodium current, is superior to flecainide in suppressing catecholamine-induced ventricular tachycardia and T-wave alternans in an intact porcine model.

Bacic D, Carneiro JS, Bento AA, Nearing BD, Rajamani S, Belardinelli L, Verrier RL.

Heart Rhythm. 2017 Mar;14(3):448-454. doi: 10.1016/j.hrthm.2016.10.021. Epub 2016 Oct 21.

PMID:
27777148
45.

Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late INai), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties.

Zablocki JA, Elzein E, Li X, Koltun DO, Parkhill EQ, Kobayashi T, Martinez R, Corkey B, Jiang H, Perry T, Kalla R, Notte GT, Saunders O, Graupe M, Lu Y, Venkataramani C, Guerrero J, Perry J, Osier M, Strickley R, Liu G, Wang WQ, Hu L, Li XJ, El-Bizri N, Hirakawa R, Kahlig K, Xie C, Li CH, Dhalla AK, Rajamani S, Mollova N, Soohoo D, Lepist EI, Murray B, Rhodes G, Belardinelli L, Desai MC.

J Med Chem. 2016 Oct 13;59(19):9005-9017. doi: 10.1021/acs.jmedchem.6b00939. Epub 2016 Oct 3.

PMID:
27690427
46.

Early somatic mosaicism is a rare cause of long-QT syndrome.

Priest JR, Gawad C, Kahlig KM, Yu JK, O'Hara T, Boyle PM, Rajamani S, Clark MJ, Garcia ST, Ceresnak S, Harris J, Boyle S, Dewey FE, Malloy-Walton L, Dunn K, Grove M, Perez MV, Neff NF, Chen R, Maeda K, Dubin A, Belardinelli L, West J, Antolik C, Macaya D, Quertermous T, Trayanova NA, Quake SR, Ashley EA.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11555-11560. Epub 2016 Sep 28.

47.

A computational model predicts adjunctive pharmacotherapy for cardiac safety via selective inhibition of the late cardiac Na current.

Yang PC, El-Bizri N, Romero L, Giles WR, Rajamani S, Belardinelli L, Clancy CE.

J Mol Cell Cardiol. 2016 Oct;99:151-161. doi: 10.1016/j.yjmcc.2016.08.011. Epub 2016 Aug 18.

48.

The novel late Na+ current inhibitor, GS-6615 (eleclazine) and its anti-arrhythmic effects in rabbit isolated heart preparations.

Rajamani S, Liu G, El-Bizri N, Guo D, Li C, Chen XL, Kahlig KM, Mollova N, Elzein E, Zablocki J, Belardinelli L.

Br J Pharmacol. 2016 Nov;173(21):3088-3098. doi: 10.1111/bph.13563. Epub 2016 Sep 14.

49.
50.

Computational analysis of fitness landscapes and evolutionary networks from in vitro evolution experiments.

Xulvi-Brunet R, Campbell GW, Rajamani S, Jiménez JI, Chen IA.

Methods. 2016 Aug 15;106:86-96. doi: 10.1016/j.ymeth.2016.05.012. Epub 2016 May 19.

PMID:
27211010

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