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Items: 11

1.

BODIPY-Caged Photoactivated Inhibitors of Cathepsin B Flip the Light Switch on Cancer Cell Apoptosis.

Toupin NP, Arora K, Shrestha P, Peterson JA, Fischer LJ, Rajagurubandara E, Podgorski I, Winter AH, Kodanko JJ.

ACS Chem Biol. 2019 Dec 20;14(12):2833-2840. doi: 10.1021/acschembio.9b00711. Epub 2019 Dec 6.

PMID:
31750642
2.

Prostate Tumor Cell-Derived IL1β Induces an Inflammatory Phenotype in Bone Marrow Adipocytes and Reduces Sensitivity to Docetaxel via Lipolysis-Dependent Mechanisms.

Herroon MK, Diedrich JD, Rajagurubandara E, Martin C, Maddipati KR, Kim S, Heath EI, Granneman J, Podgorski I.

Mol Cancer Res. 2019 Dec;17(12):2508-2521. doi: 10.1158/1541-7786.MCR-19-0540. Epub 2019 Sep 27.

PMID:
31562254
3.

The Lipid Side of Bone Marrow Adipocytes: How Tumor Cells Adapt and Survive in Bone.

Diedrich JD, Herroon MK, Rajagurubandara E, Podgorski I.

Curr Osteoporos Rep. 2018 Aug;16(4):443-457. doi: 10.1007/s11914-018-0453-9. Review.

4.

Adipocyte-activated oxidative and ER stress pathways promote tumor survival in bone via upregulation of Heme Oxygenase 1 and Survivin.

Herroon MK, Rajagurubandara E, Diedrich JD, Heath EI, Podgorski I.

Sci Rep. 2018 Jan 8;8(1):40. doi: 10.1038/s41598-017-17800-5.

5.

Bone marrow adipocytes promote the Warburg phenotype in metastatic prostate tumors via HIF-1α activation.

Diedrich JD, Rajagurubandara E, Herroon MK, Mahapatra G, Hüttemann M, Podgorski I.

Oncotarget. 2016 Oct 4;7(40):64854-64877. doi: 10.18632/oncotarget.11712.

6.

Photoactivated inhibition of cathepsin K in a 3D tumor model.

Herroon MK, Sharma R, Rajagurubandara E, Turro C, Kodanko JJ, Podgorski I.

Biol Chem. 2016 Jun 1;397(6):571-82. doi: 10.1515/hsz-2015-0274.

7.

Marrow adipocyte-derived CXCL1 and CXCL2 contribute to osteolysis in metastatic prostate cancer.

Hardaway AL, Herroon MK, Rajagurubandara E, Podgorski I.

Clin Exp Metastasis. 2015 Apr;32(4):353-68. doi: 10.1007/s10585-015-9714-5. Epub 2015 Mar 24.

8.

Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases.

Hardaway AL, Herroon MK, Rajagurubandara E, Podgorski I.

Cancer Metastasis Rev. 2014 Sep;33(2-3):527-43. doi: 10.1007/s10555-013-9484-y. Review.

9.

Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms.

Herroon MK, Rajagurubandara E, Hardaway AL, Powell K, Turchick A, Feldmann D, Podgorski I.

Oncotarget. 2013 Nov;4(11):2108-23.

10.

Macrophage cathepsin K promotes prostate tumor progression in bone.

Herroon MK, Rajagurubandara E, Rudy DL, Chalasani A, Hardaway AL, Podgorski I.

Oncogene. 2013 Mar 21;32(12):1580-93. doi: 10.1038/onc.2012.166. Epub 2012 May 21.

11.

Determinants of sequence-specificity within human AID and APOBEC3G.

Carpenter MA, Rajagurubandara E, Wijesinghe P, Bhagwat AS.

DNA Repair (Amst). 2010 May 4;9(5):579-87. doi: 10.1016/j.dnarep.2010.02.010. Epub 2010 Mar 24.

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