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Items: 26

1.

The large protein 'L' of Peste-des-petits-ruminants virus exhibits RNA triphosphatase activity, the first enzyme in mRNA capping pathway.

Ansari MY, Singh PK, Rajagopalan D, Shanmugam P, Bellur A, Shaila MS.

Virus Genes. 2019 Feb;55(1):68-75. doi: 10.1007/s11262-018-1617-5. Epub 2018 Dec 3.

2.

TIP60 represses activation of endogenous retroviral elements.

Rajagopalan D, Tirado-Magallanes R, Bhatia SS, Teo WS, Sian S, Hora S, Lee KK, Zhang Y, Jadhav SP, Wu Y, Gan YH, Karnani N, Benoukraf T, Jha S.

Nucleic Acids Res. 2018 Oct 12;46(18):9456-9470. doi: 10.1093/nar/gky659.

3.

An epi(c)genetic war: Pathogens, cancer and human genome.

Rajagopalan D, Jha S.

Biochim Biophys Acta Rev Cancer. 2018 Apr;1869(2):333-345. doi: 10.1016/j.bbcan.2018.04.003. Epub 2018 Apr 13. Review.

4.

Id Proteins Suppress E2A-Driven Invariant Natural Killer T Cell Development prior to TCR Selection.

Roy S, Moore AJ, Love C, Reddy A, Rajagopalan D, Dave SS, Li L, Murre C, Zhuang Y.

Front Immunol. 2018 Jan 24;9:42. doi: 10.3389/fimmu.2018.00042. eCollection 2018.

5.

TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter.

Rajagopalan D, Pandey AK, Xiuzhen MC, Lee KK, Hora S, Zhang Y, Chua BH, Kwok HS, Bhatia SS, Deng LW, Tenen DG, Kappei D, Jha S.

PLoS Pathog. 2017 Oct 18;13(10):e1006681. doi: 10.1371/journal.ppat.1006681. eCollection 2017 Oct.

6.

Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma.

Reddy A, Zhang J, Davis NS, Moffitt AB, Love CL, Waldrop A, Leppa S, Pasanen A, Meriranta L, Karjalainen-Lindsberg ML, Nørgaard P, Pedersen M, Gang AO, Høgdall E, Heavican TB, Lone W, Iqbal J, Qin Q, Li G, Kim SY, Healy J, Richards KL, Fedoriw Y, Bernal-Mizrachi L, Koff JL, Staton AD, Flowers CR, Paltiel O, Goldschmidt N, Calaminici M, Clear A, Gribben J, Nguyen E, Czader MB, Ondrejka SL, Collie A, Hsi ED, Tse E, Au-Yeung RKH, Kwong YL, Srivastava G, Choi WWL, Evens AM, Pilichowska M, Sengar M, Reddy N, Li S, Chadburn A, Gordon LI, Jaffe ES, Levy S, Rempel R, Tzeng T, Happ LE, Dave T, Rajagopalan D, Datta J, Dunson DB, Dave SS.

Cell. 2017 Oct 5;171(2):481-494.e15. doi: 10.1016/j.cell.2017.09.027.

7.

Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2.

Moffitt AB, Ondrejka SL, McKinney M, Rempel RE, Goodlad JR, Teh CH, Leppa S, Mannisto S, Kovanen PE, Tse E, Au-Yeung RKH, Kwong YL, Srivastava G, Iqbal J, Yu J, Naresh K, Villa D, Gascoyne RD, Said J, Czader MB, Chadburn A, Richards KL, Rajagopalan D, Davis NS, Smith EC, Palus BC, Tzeng TJ, Healy JA, Lugar PL, Datta J, Love C, Levy S, Dunson DB, Zhuang Y, Hsi ED, Dave SS.

J Exp Med. 2017 May 1;214(5):1371-1386. doi: 10.1084/jem.20160894. Epub 2017 Apr 19.

8.

Id2 Collaborates with Id3 To Suppress Invariant NKT and Innate-like Tumors.

Li J, Roy S, Kim YM, Li S, Zhang B, Love C, Reddy A, Rajagopalan D, Dave S, Diehl AM, Zhuang Y.

J Immunol. 2017 Apr 15;198(8):3136-3148. doi: 10.4049/jimmunol.1601935. Epub 2017 Mar 3.

9.

The Genetic Basis of Hepatosplenic T-cell Lymphoma.

McKinney M, Moffitt AB, Gaulard P, Travert M, De Leval L, Nicolae A, Raffeld M, Jaffe ES, Pittaluga S, Xi L, Heavican T, Iqbal J, Belhadj K, Delfau-Larue MH, Fataccioli V, Czader MB, Lossos IS, Chapman-Fredricks JR, Richards KL, Fedoriw Y, Ondrejka SL, Hsi ED, Low L, Weisenburger D, Chan WC, Mehta-Shah N, Horwitz S, Bernal-Mizrachi L, Flowers CR, Beaven AW, Parihar M, Baseggio L, Parrens M, Moreau A, Sujobert P, Pilichowska M, Evens AM, Chadburn A, Au-Yeung RK, Srivastava G, Choi WW, Goodlad JR, Aurer I, Basic-Kinda S, Gascoyne RD, Davis NS, Li G, Zhang J, Rajagopalan D, Reddy A, Love C, Levy S, Zhuang Y, Datta J, Dunson DB, Davé SS.

Cancer Discov. 2017 Apr;7(4):369-379. doi: 10.1158/2159-8290.CD-16-0330. Epub 2017 Jan 25.

10.

TIP60 inhibits metastasis by ablating DNMT1-SNAIL2-driven epithelial-mesenchymal transition program.

Zhang Y, Subbaiah VK, Rajagopalan D, Tham CY, Abdullah LN, Toh TB, Gong M, Tan TZ, Jadhav SP, Pandey AK, Karnani N, Chow EK, Thiery JP, Jha S.

J Mol Cell Biol. 2016 Sep 20. pii: mjw038. [Epub ahead of print]

PMID:
27651430
11.

E3 ligase EDD1/UBR5 is utilized by the HPV E6 oncogene to destabilize tumor suppressor TIP60.

Subbaiah VK, Zhang Y, Rajagopalan D, Abdullah LN, Yeo-Teh NS, Tomaić V, Banks L, Myers MP, Chow EK, Jha S.

Oncogene. 2016 Apr 21;35(16):2062-74. doi: 10.1038/onc.2015.268. Epub 2015 Aug 3.

PMID:
26234678
12.

Synaptic, transcriptional and chromatin genes disrupted in autism.

De Rubeis S, He X, Goldberg AP, Poultney CS, Samocha K, Cicek AE, Kou Y, Liu L, Fromer M, Walker S, Singh T, Klei L, Kosmicki J, Shih-Chen F, Aleksic B, Biscaldi M, Bolton PF, Brownfeld JM, Cai J, Campbell NG, Carracedo A, Chahrour MH, Chiocchetti AG, Coon H, Crawford EL, Curran SR, Dawson G, Duketis E, Fernandez BA, Gallagher L, Geller E, Guter SJ, Hill RS, Ionita-Laza J, Jimenz Gonzalez P, Kilpinen H, Klauck SM, Kolevzon A, Lee I, Lei I, Lei J, Lehtimäki T, Lin CF, Ma'ayan A, Marshall CR, McInnes AL, Neale B, Owen MJ, Ozaki N, Parellada M, Parr JR, Purcell S, Puura K, Rajagopalan D, Rehnström K, Reichenberg A, Sabo A, Sachse M, Sanders SJ, Schafer C, Schulte-Rüther M, Skuse D, Stevens C, Szatmari P, Tammimies K, Valladares O, Voran A, Li-San W, Weiss LA, Willsey AJ, Yu TW, Yuen RK; DDD Study; Homozygosity Mapping Collaborative for Autism; UK10K Consortium, Cook EH, Freitag CM, Gill M, Hultman CM, Lehner T, Palotie A, Schellenberg GD, Sklar P, State MW, Sutcliffe JS, Walsh CA, Scherer SW, Zwick ME, Barett JC, Cutler DJ, Roeder K, Devlin B, Daly MJ, Buxbaum JD.

Nature. 2014 Nov 13;515(7526):209-15. doi: 10.1038/nature13772. Epub 2014 Oct 29.

13.

Relationships between pazopanib exposure and clinical safety and efficacy in patients with advanced renal cell carcinoma.

Suttle AB, Ball HA, Molimard M, Hutson TE, Carpenter C, Rajagopalan D, Lin Y, Swann S, Amado R, Pandite L.

Br J Cancer. 2014 Nov 11;111(10):1909-16. doi: 10.1038/bjc.2014.503. Epub 2014 Oct 28. Erratum in: Br J Cancer. 2014 Dec 9;111(12):2383.

14.

DDD-028: a potent potential non-opioid, non-cannabinoid analgesic for neuropathic and inflammatory pain.

Rajagopalan P, Tracey H, Chen Z, Bandyopadhyaya A, Veeraraghavan S, Rajagopalan DR, Salvemini D, McPhee I, Viswanadha S, Rajagopalan R.

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3088-91. doi: 10.1016/j.bmcl.2014.05.016. Epub 2014 May 14.

PMID:
24863744
15.

The synthesis and comparative receptor binding affinities of novel, isomeric pyridoindolobenzazepine scaffolds.

Rajagopalan R, Bandyopadhyaya A, Rajagopalan DR, Rajagopalan P.

Bioorg Med Chem Lett. 2014 Jan 15;24(2):576-9. doi: 10.1016/j.bmcl.2013.12.024. Epub 2013 Dec 11.

PMID:
24365159
16.

The C-terminal domain of CblD interacts with CblC and influences intracellular cobalamin partitioning.

Gherasim C, Hannibal L, Rajagopalan D, Jacobsen DW, Banerjee R.

Biochimie. 2013 May;95(5):1023-32. doi: 10.1016/j.biochi.2013.02.003. Epub 2013 Feb 14.

17.

Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes.

Xu CF, Bing NX, Ball HA, Rajagopalan D, Sternberg CN, Hutson TE, de Souza P, Xue ZG, McCann L, King KS, Ragone LJ, Whittaker JC, Spraggs CF, Cardon LR, Mooser VE, Pandite LN.

J Clin Oncol. 2011 Jun 20;29(18):2557-64. doi: 10.1200/JCO.2010.32.9110. Epub 2011 May 16.

PMID:
21576632
18.

Plasma cytokine and angiogenic factor profiling identifies markers associated with tumor shrinkage in early-stage non-small cell lung cancer patients treated with pazopanib.

Nikolinakos PG, Altorki N, Yankelevitz D, Tran HT, Yan S, Rajagopalan D, Bordogna W, Ottesen LH, Heymach JV.

Cancer Res. 2010 Mar 15;70(6):2171-9. doi: 10.1158/0008-5472.CAN-09-2533. Epub 2010 Mar 9.

19.

The role of positive selection in determining the molecular cause of species differences in disease.

Vamathevan JJ, Hasan S, Emes RD, Amrine-Madsen H, Rajagopalan D, Topp SD, Kumar V, Word M, Simmons MD, Foord SM, Sanseau P, Yang Z, Holbrook JD.

BMC Evol Biol. 2008 Oct 6;8:273. doi: 10.1186/1471-2148-8-273.

20.

A global pathway crosstalk network.

Li Y, Agarwal P, Rajagopalan D.

Bioinformatics. 2008 Jun 15;24(12):1442-7. doi: 10.1093/bioinformatics/btn200. Epub 2008 Apr 23.

PMID:
18434343
21.

P38 MAPK inhibitors suppress biomarkers of hypertension end-organ damage, osteopontin and plasminogen activator inhibitor-1.

Nerurkar SS, Olzinski AR, Frazier KS, Mirabile RC, O'Brien SP, Jing J, Rajagopalan D, Yue TL, Willette RN.

Biomarkers. 2007 Jan-Feb;12(1):87-112.

PMID:
17438656
22.

A comparison of statistical tests for detecting differential expression using Affymetrix oligonucleotide microarrays.

Vardhanabhuti S, Blakemore SJ, Clark SM, Ghosh S, Stephens RJ, Rajagopalan D.

OMICS. 2006 Winter;10(4):555-66.

PMID:
17233564
23.

Inferring pathways from gene lists using a literature-derived network of biological relationships.

Rajagopalan D, Agarwal P.

Bioinformatics. 2005 Mar;21(6):788-93. Epub 2004 Oct 27.

PMID:
15509611
24.

A comparison of statistical methods for analysis of high density oligonucleotide array data.

Rajagopalan D.

Bioinformatics. 2003 Aug 12;19(12):1469-76.

PMID:
12912826
25.

Frogs as carriers of rare Salmonella serotypes.

Rajagopalan D, Deshpande CK, Joshi LM.

J Postgrad Med. 1984 Apr;30(2):85-8. No abstract available.

PMID:
6527302
26.

Lactose positive Salmonella inpraw from processed frog legs.

Rajagopalan D, Deshpande CK, Joshi L.

Indian J Med Res. 1983 Aug;78:177-80. No abstract available.

PMID:
6654407

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