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Items: 1 to 50 of 894

1.

Temperament profiles are associated with dietary behavior from childhood to adulthood.

Lipsanen J, Elovainio M, Hakulinen C, Tremblay MS, Rovio S, Lagström H, Jaakkola JM, Jula A, Rönnemaa T, Viikari J, Niinikoski H, Simell O, Raitakari OT, Pahkala K, Pulkki-Råback L.

Appetite. 2020 Apr 3:104681. doi: 10.1016/j.appet.2020.104681. [Epub ahead of print]

PMID:
32251766
2.

The Young Finns Study.

Rovio SP, Pihlman J, Pahkala K, Juonala M, Magnussen CG, Pitkänen N, Ahola-Olli A, Salo P, Kähönen M, Hutri-Kähönen N, Lehtimäki T, Jokinen E, Laitinen T, Taittonen L, Tossavainen P, Viikari JSA, Raitakari OT.

Am J Epidemiol. 2020 Apr 3. pii: kwaa052. doi: 10.1093/aje/kwaa052. [Epub ahead of print]

PMID:
32242223
3.

The contribution of neighborhood socioeconomic disadvantage on depressive symptoms over the adult lifetime: a 32-year prospective cohort study.

Elovainio M, Vahtera J, Pentti J, Hakulinen C, Pulkki-Råback L, Lipsanen J, Virtanen M, Keltikangas-Järvinen L, Kivimäki M, Kähönen M, Viikari J, Lehtimäki T, Raitakari O.

Am J Epidemiol. 2020 Apr 2. pii: kwaa026. doi: 10.1093/aje/kwaa026. [Epub ahead of print]

PMID:
32239174
4.

Non-HDL Cholesterol Levels in Childhood and Carotid Intima-Media Thickness in Adulthood.

Juonala M, Wu F, Sinaiko A, Woo JG, Urbina EM, Jacobs D, Steinberger J, Prineas R, Koskinen J, Sabin MA, Burgner DP, Burns TL, Bazzano L, Venn A, Viikari JSA, Hutri-Kähönen N, Daniels SR, Dwyer T, Raitakari OT, Magnussen CG.

Pediatrics. 2020 Apr;145(4). pii: e20192114. doi: 10.1542/peds.2019-2114. Epub 2020 Mar 24.

PMID:
32209701
5.

Dietary Fats and Atherosclerosis From Childhood to Adulthood.

Laitinen TT, Nuotio J, Rovio SP, Niinikoski H, Juonala M, Magnussen CG, Jokinen E, Lagström H, Jula A, Viikari JSA, Rönnemaa T, Simell O, Raitakari OT, Pahkala K.

Pediatrics. 2020 Apr;145(4). pii: e20192786. doi: 10.1542/peds.2019-2786. Epub 2020 Mar 24.

PMID:
32209700
6.

Early cardiovascular structural and functional abnormalities as a guide to future morbid events.

Koskinen JS, Raitakari OT.

Eur J Prev Cardiol. 2020 Mar 24:2047487320908700. doi: 10.1177/2047487320908700. [Epub ahead of print] No abstract available.

PMID:
32208751
7.

Education leads to a more physically active lifestyle: Evidence based on Mendelian randomization.

Kari JT, Viinikainen J, Böckerman P, Tammelin TH, Pitkänen N, Lehtimäki T, Pahkala K, Hirvensalo M, Raitakari OT, Pehkonen J.

Scand J Med Sci Sports. 2020 Mar 16. doi: 10.1111/sms.13653. [Epub ahead of print]

PMID:
32176397
8.

Cardiovascular Health Trajectories From Childhood Through Middle Age and Their Association With Subclinical Atherosclerosis.

Allen NB, Krefman AE, Labarthe D, Greenland P, Juonala M, Kähönen M, Lehtimäki T, Day RS, Bazzano LA, Van Horn LV, Liu L, Alonso CF, Webber LS, Pahkala K, Laitinen TT, Raitakari OT, Lloyd-Jones DM.

JAMA Cardiol. 2020 Mar 11. doi: 10.1001/jamacardio.2020.0140. [Epub ahead of print]

PMID:
32159727
9.

Genome-wide association meta-analysis of nicotine metabolism and cigarette consumption measures in smokers of European descent.

Buchwald J, Chenoweth MJ, Palviainen T, Zhu G, Benner C, Gordon S, Korhonen T, Ripatti S, Madden PAF, Lehtimäki T, Raitakari OT, Salomaa V, Rose RJ, George TP, Lerman C, Pirinen M, Martin NG, Kaprio J, Loukola A, Tyndale RF.

Mol Psychiatry. 2020 Mar 10. doi: 10.1038/s41380-020-0702-z. [Epub ahead of print]

PMID:
32157176
10.

Correction: Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition.

Kettunen J, Holmes MV, Allara E, Anufrieva O, Ohukainen P, Oliver-Williams C, Wang Q, Tillin T, Hughes AD, Kähönen M, Lehtimäki T, Viikari J, Raitakari OT, Salomaa V, Järvelin MR, Perola M, Smith GD, Chaturvedi N, Danesh J, Di Angelantonio E, Butterworth AS, Ala-Korpela M.

PLoS Biol. 2020 Mar 6;18(3):e3000694. doi: 10.1371/journal.pbio.3000694. eCollection 2020 Mar.

11.

Apolipoprotein A-I concentrations and risk of coronary artery disease: A Mendelian randomization study.

Karjalainen MK, Holmes MV, Wang Q, Anufrieva O, Kähönen M, Lehtimäki T, Havulinna AS, Kristiansson K, Salomaa V, Perola M, Viikari JS, Raitakari OT, Järvelin MR, Ala-Korpela M, Kettunen J.

Atherosclerosis. 2020 Feb 14. pii: S0021-9150(20)30081-2. doi: 10.1016/j.atherosclerosis.2020.02.002. [Epub ahead of print]

12.

Do childhood infections affect labour market outcomes in adulthood and, if so, how?

Viinikainen J, Bryson A, Böckerman P, Elovainio M, Hutri-Kähönen N, Juonala M, Lehtimäki T, Pahkala K, Rovio S, Pulkki-Råback L, Raitakari O, Pehkonen J.

Econ Hum Biol. 2020 Jan 30;37:100857. doi: 10.1016/j.ehb.2020.100857. [Epub ahead of print]

13.

Easy-to-use tool for evaluating the elevated acute kidney injury risk against reduced cardiovascular disease risk during intensive blood pressure control.

Venäläinen MS, Klén R, Mahmoudian M, Raitakari OT, Elo LL.

J Hypertens. 2020 Mar;38(3):511-518. doi: 10.1097/HJH.0000000000002282.

PMID:
31977572
14.

EpiMetal: an open-source graphical web browser tool for easy statistical analyses in epidemiology and metabolomics.

Ekholm J, Ohukainen P, Kangas AJ, Kettunen J, Wang Q, Karsikas M, Khan AA, Kingwell BA, Kähönen M, Lehtimäki T, Raitakari OT, Järvelin MR, Meikle PJ, Ala-Korpela M.

Int J Epidemiol. 2020 Jan 16. pii: dyz244. doi: 10.1093/ije/dyz244. [Epub ahead of print]

PMID:
31943015
15.

Influence of Genetic Variation in PDE3A on Endothelial Function and Stroke.

Traylor M, Amin Al Olama A, Lyytikäinen LP, Marini S, Chung J, Malik R, Dichgans M, Kähönen M, Lehtimäki T, Anderson CD, Raitakari OT, Markus HS.

Hypertension. 2020 Feb;75(2):365-371. doi: 10.1161/HYPERTENSIONAHA.119.13513. Epub 2019 Dec 23.

16.

Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition.

Kettunen J, Holmes MV, Allara E, Anufrieva O, Ohukainen P, Oliver-Williams C, Wang Q, Tillin T, Hughes AD, Kähönen M, Lehtimäki T, Viikari J, Raitakari OT, Salomaa V, Järvelin MR, Perola M, Davey Smith G, Chaturvedi N, Danesh J, Di Angelantonio E, Butterworth AS, Ala-Korpela M.

PLoS Biol. 2019 Dec 20;17(12):e3000572. doi: 10.1371/journal.pbio.3000572. eCollection 2019 Dec. Erratum in: PLoS Biol. 2020 Mar 6;18(3):e3000694.

17.

Childhood risk factors and carotid atherosclerotic plaque in adulthood: The Cardiovascular Risk in Young Finns Study.

Koskinen JS, Kytö V, Juonala M, Viikari JSA, Nevalainen J, Kähönen M, Lehtimäki T, Hutri-Kähönen N, Laitinen T, Tossavainen P, Jokinen E, Magnussen CG, Raitakari OT.

Atherosclerosis. 2020 Jan;293:18-25. doi: 10.1016/j.atherosclerosis.2019.11.029. Epub 2019 Nov 30.

PMID:
31830725
18.

Breastfeeding and offspring's compassion and empathy in adulthood: A study with an over 30-year follow-up.

Saarinen AIL, Keltikangas-Järvinen L, Honda Y, Oksman E, Raitakari O, Pulkki-Råback L, Hintsanen M.

Scand J Psychol. 2020 Apr;61(2):227-236. doi: 10.1111/sjop.12600. Epub 2019 Dec 10.

PMID:
31823393
19.

Lipidomic architecture shared by subclinical markers of osteoporosis and atherosclerosis: The Cardiovascular Risk in Young Finns Study.

Mishra BH, Mishra PP, Mononen N, Hilvo M, Sievänen H, Juonala M, Laaksonen M, Hutri-Kähönen N, Viikari J, Kähönen M, Raitakari OT, Laaksonen R, Lehtimäki T.

Bone. 2020 Feb;131:115160. doi: 10.1016/j.bone.2019.115160. Epub 2019 Nov 21.

20.

Age-Specific Estimates and Comparisons of Youth Tri-Ponderal Mass Index and Body Mass Index in Predicting Adult Obesity-Related Outcomes.

Wu F, Buscot MJ, Niinikoski H, Rovio SP, Juonala M, Sabin MA, Jula A, Rönnemaa T, Viikari JSA, Raitakari OT, Magnussen CG, Pahkala K.

J Pediatr. 2020 Mar;218:198-203.e6. doi: 10.1016/j.jpeds.2019.10.062. Epub 2019 Nov 19.

PMID:
31757470
21.

Childhood Psychosocial Environment and Adult Cardiac Health: A Causal Mediation Approach.

Komulainen K, Mittleman MA, Ruohonen S, Laitinen TT, Pahkala K, Elovainio M, Tammelin T, Kähönen M, Juonala M, Keltikangas-Järvinen L, Raitakari O, Pulkki-Råback L, Jokela M.

Am J Prev Med. 2019 Dec;57(6):e195-e202. doi: 10.1016/j.amepre.2019.08.018.

PMID:
31753272
22.

Three genetic-environmental networks for human personality.

Zwir I, Del-Val C, Arnedo J, Pulkki-Råback L, Konte B, Yang SS, Romero-Zaliz R, Hintsanen M, Cloninger KM, Garcia D, Svrakic DM, Lester N, Rozsa S, Mesa A, Lyytikäinen LP, Giegling I, Kähönen M, Martinez M, Seppälä I, Raitoharju E, de Erausquin GA, Mamah D, Raitakari O, Rujescu D, Postolache TT, Gu CC, Sung J, Lehtimäki T, Keltikangas-Järvinen L, Cloninger CR.

Mol Psychiatry. 2019 Nov 21. doi: 10.1038/s41380-019-0579-x. [Epub ahead of print]

PMID:
31748689
23.

Increase in adiposity from childhood to adulthood predicts a metabolically obese phenotype in normal-weight adults.

Viitasalo A, Pitkänen N, Pahkala K, Lehtimäki T, Viikari JSA, Raitakari O, Kilpeläinen TO.

Int J Obes (Lond). 2020 Apr;44(4):848-851. doi: 10.1038/s41366-019-0479-9. Epub 2019 Nov 19.

PMID:
31745257
24.

Associations of Leisure-Time Physical Activity Trajectories with Fruit and Vegetable Consumption from Childhood to Adulthood: The Cardiovascular Risk in Young Finns Study.

Lounassalo I, Hirvensalo M, Kankaanpää A, Tolvanen A, Palomäki S, Salin K, Fogelholm M, Yang X, Pahkala K, Rovio S, Hutri-Kähönen N, Raitakari O, Tammelin TH.

Int J Environ Res Public Health. 2019 Nov 12;16(22). pii: E4437. doi: 10.3390/ijerph16224437.

25.

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.

Noordam R, Bos MM, Wang H, Winkler TW, Bentley AR, Kilpeläinen TO, de Vries PS, Sung YJ, Schwander K, Cade BE, Manning A, Aschard H, Brown MR, Chen H, Franceschini N, Musani SK, Richard M, Vojinovic D, Aslibekyan S, Bartz TM, de Las Fuentes L, Feitosa M, Horimoto AR, Ilkov M, Kho M, Kraja A, Li C, Lim E, Liu Y, Mook-Kanamori DO, Rankinen T, Tajuddin SM, van der Spek A, Wang Z, Marten J, Laville V, Alver M, Evangelou E, Graff ME, He M, Kühnel B, Lyytikäinen LP, Marques-Vidal P, Nolte IM, Palmer ND, Rauramaa R, Shu XO, Snieder H, Weiss S, Wen W, Yanek LR, Adolfo C, Ballantyne C, Bielak L, Biermasz NR, Boerwinkle E, Dimou N, Eiriksdottir G, Gao C, Gharib SA, Gottlieb DJ, Haba-Rubio J, Harris TB, Heikkinen S, Heinzer R, Hixson JE, Homuth G, Ikram MA, Komulainen P, Krieger JE, Lee J, Liu J, Lohman KK, Luik AI, Mägi R, Martin LW, Meitinger T, Metspalu A, Milaneschi Y, Nalls MA, O'Connell J, Peters A, Peyser P, Raitakari OT, Reiner AP, Rensen PCN, Rice TK, Rich SS, Roenneberg T, Rotter JI, Schreiner PJ, Shikany J, Sidney SS, Sims M, Sitlani CM, Sofer T, Strauch K, Swertz MA, Taylor KD, Uitterlinden AG, van Duijn CM, Völzke H, Waldenberger M, Wallance RB, van Dijk KW, Yu C, Zonderman AB, Becker DM, Elliott P, Esko T, Gieger C, Grabe HJ, Lakka TA, Lehtimäki T, North KE, Penninx BWJH, Vollenweider P, Wagenknecht LE, Wu T, Xiang YB, Zheng W, Arnett DK, Bouchard C, Evans MK, Gudnason V, Kardia S, Kelly TN, Kritchevsky SB, Loos RJF, Pereira AC, Province M, Psaty BM, Rotimi C, Zhu X, Amin N, Cupples LA, Fornage M, Fox EF, Guo X, Gauderman WJ, Rice K, Kooperberg C, Munroe PB, Liu CT, Morrison AC, Rao DC, van Heemst D, Redline S.

Nat Commun. 2019 Nov 12;10(1):5121. doi: 10.1038/s41467-019-12958-0.

26.

Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.

Nath AP, Ritchie SC, Grinberg NF, Tang HH, Huang QQ, Teo SM, Ahola-Olli AV, Würtz P, Havulinna AS, Santalahti K, Pitkänen N, Lehtimäki T, Kähönen M, Lyytikäinen LP, Raitoharju E, Seppälä I, Sarin AP, Ripatti S, Palotie A, Perola M, Viikari JS, Jalkanen S, Maksimow M, Salmi M, Wallace C, Raitakari OT, Salomaa V, Abraham G, Kettunen J, Inouye M.

Am J Hum Genet. 2019 Dec 5;105(6):1076-1090. doi: 10.1016/j.ajhg.2019.10.001. Epub 2019 Oct 31.

PMID:
31679650
27.

Long-Term Burden of Increased Body Mass Index from Childhood on Adult Dyslipidemia: The i3C Consortium Study.

Yan Y, Bazzano LA, Juonala M, Raitakari OT, Viikari JSA, Prineas R, Dwyer T, Sinaiko A, Burns TL, Daniels SR, Woo JG, Khoury PR, Urbina EM, Jacobs DR Jr, Hu T, Steinberger J, Venn A, Chen W.

J Clin Med. 2019 Oct 18;8(10). pii: E1725. doi: 10.3390/jcm8101725.

28.

Associations Between Trajectories of Leisure-Time Physical Activity and Television Viewing Time Across Adulthood: The Cardiovascular Risk in Young Finns Study.

Yang X, Lounassalo I, Kankaanpää A, Hirvensalo M, Rovio SP, Tolvanen A, Biddle SJH, Helajärvi H, Palomäki SH, Salin K, Hutri-Kähönen N, Raitakari OT, Tammelin TH.

J Phys Act Health. 2019 Oct 10:1-7. doi: 10.1123/jpah.2018-0650. [Epub ahead of print]

PMID:
31600733
29.

Prediction of adult class II/III obesity from childhood BMI: the i3C consortium.

Woo JG, Zhang N, Fenchel M, Jacobs DR Jr, Hu T, Urbina EM, Burns TL, Raitakari O, Steinberger J, Bazzano L, Prineas RJ, Jaquish C, Juonala M, Ryder JR, Daniels SR, Sinaiko A, Dwyer T, Venn A.

Int J Obes (Lond). 2019 Oct 9. doi: 10.1038/s41366-019-0461-6. [Epub ahead of print]

PMID:
31597933
30.

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts.

Ahola-Olli AV, Mustelin L, Kalimeri M, Kettunen J, Jokelainen J, Auvinen J, Puukka K, Havulinna AS, Lehtimäki T, Kähönen M, Juonala M, Keinänen-Kiukaanniemi S, Salomaa V, Perola M, Järvelin MR, Ala-Korpela M, Raitakari O, Würtz P.

Diabetologia. 2019 Dec;62(12):2298-2309. doi: 10.1007/s00125-019-05001-w. Epub 2019 Oct 4.

31.

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

Tin A, Marten J, Halperin Kuhns VL, Li Y, Wuttke M, Kirsten H, Sieber KB, Qiu C, Gorski M, Yu Z, Giri A, Sveinbjornsson G, Li M, Chu AY, Hoppmann A, O'Connor LJ, Prins B, Nutile T, Noce D, Akiyama M, Cocca M, Ghasemi S, van der Most PJ, Horn K, Xu Y, Fuchsberger C, Sedaghat S, Afaq S, Amin N, Ärnlöv J, Bakker SJL, Bansal N, Baptista D, Bergmann S, Biggs ML, Biino G, Boerwinkle E, Bottinger EP, Boutin TS, Brumat M, Burkhardt R, Campana E, Campbell A, Campbell H, Carroll RJ, Catamo E, Chambers JC, Ciullo M, Concas MP, Coresh J, Corre T, Cusi D, Felicita SC, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Delgado G, Demirkan A, Devuyst O, Dittrich K, Eckardt KU, Ehret G, Endlich K, Evans MK, Gansevoort RT, Gasparini P, Giedraitis V, Gieger C, Girotto G, Gögele M, Gordon SD, Gudbjartsson DF, Gudnason V; German Chronic Kidney Disease Study, Haller T, Hamet P, Harris TB, Hayward C, Hicks AA, Hofer E, Holm H, Huang W, Hutri-Kähönen N, Hwang SJ, Ikram MA, Lewis RM, Ingelsson E, Jakobsdottir J, Jonsdottir I, Jonsson H, Joshi PK, Josyula NS, Jung B, Kähönen M, Kamatani Y, Kanai M, Kerr SM, Kiess W, Kleber ME, Koenig W, Kooner JS, Körner A, Kovacs P, Krämer BK, Kronenberg F, Kubo M, Kühnel B, La Bianca M, Lange LA, Lehne B, Lehtimäki T; Lifelines Cohort Study, Liu J, Loeffler M, Loos RJF, Lyytikäinen LP, Magi R, Mahajan A, Martin NG, März W, Mascalzoni D, Matsuda K, Meisinger C, Meitinger T, Metspalu A, Milaneschi Y; V. A. Million Veteran Program, O'Donnell CJ, Wilson OD, Gaziano JM, Mishra PP, Mohlke KL, Mononen N, Montgomery GW, Mook-Kanamori DO, Müller-Nurasyid M, Nadkarni GN, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Noordam R, O'Connell JR, Olafsson I, Padmanabhan S, Penninx BWJH, Perls T, Peters A, Pirastu M, Pirastu N, Pistis G, Polasek O, Ponte B, Porteous DJ, Poulain T, Preuss MH, Rabelink TJ, Raffield LM, Raitakari OT, Rettig R, Rheinberger M, Rice KM, Rizzi F, Robino A, Rudan I, Krajcoviechova A, Cifkova R, Rueedi R, Ruggiero D, Ryan KA, Saba Y, Salvi E, Schmidt H, Schmidt R, Shaffer CM, Smith AV, Smith BH, Spracklen CN, Strauch K, Stumvoll M, Sulem P, Tajuddin SM, Teren A, Thiery J, Thio CHL, Thorsteinsdottir U, Toniolo D, Tönjes A, Tremblay J, Uitterlinden AG, Vaccargiu S, van der Harst P, van Duijn CM, Verweij N, Völker U, Vollenweider P, Waeber G, Waldenberger M, Whitfield JB, Wild SH, Wilson JF, Yang Q, Zhang W, Zonderman AB, Bochud M, Wilson JG, Pendergrass SA, Ho K, Parsa A, Pramstaller PP, Psaty BM, Böger CA, Snieder H, Butterworth AS, Okada Y, Edwards TL, Stefansson K, Susztak K, Scholz M, Heid IM, Hung AM, Teumer A, Pattaro C, Woodward OM, Vitart V, Köttgen A.

Nat Genet. 2019 Oct;51(10):1459-1474. doi: 10.1038/s41588-019-0504-x. Epub 2019 Oct 2.

32.

Associations Between Early Childcare Environment and Different Aspects of Adulthood Sociability: The 32-Year Prospective Young Finns Study.

Oksman E, Rosenström T, Gluschkoff K, Saarinen A, Hintsanen M, Pulkki-Råback L, Viikari J, Raitakari OT, Keltikangas-Järvinen L.

Front Psychol. 2019 Sep 10;10:2060. doi: 10.3389/fpsyg.2019.02060. eCollection 2019.

33.

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study.

BIRTH-GENE (BIG) Study Working Group, Huang T, Wang T, Zheng Y, Ellervik C, Li X, Gao M, Fang Z, Chai JF, Ahluwalia TVS, Wang Y, Voortman T, Noordam R, Frazier-Wood A, Scholz M, Sonestedt E, Akiyama M, Dorajoo R, Zhou A, Kilpeläinen TO, Kleber ME, Crozier SR, Godfrey KM, Lemaitre R, Felix JF, Shi Y, Gupta P, Khor CC, Lehtimäki T, Wang CA, Tiesler CMT, Thiering E, Standl M, Rzehak P, Marouli E, He M, Lecoeur C, Corella D, Lai CQ, Moreno LA, Pitkänen N, Boreham CA, Zhang T, Saw SM, Ridker PM, Graff M, van Rooij FJA, Uitterlinden AG, Hofman A, van Heemst D, Rosendaal FR, de Mutsert R, Burkhardt R, Schulz CA, Ericson U, Kamatani Y, Yuan JM, Power C, Hansen T, Sørensen TIA, Tjønneland A, Overvad K, Delgado G, Cooper C, Djousse L, Rivadeneira F, Jameson K, Zhao W, Liu J, Lee NR, Raitakari O, Kähönen M, Viikari J, Grote V, Langhendries JP, Koletzko B, Escribano J, Verduci E, Dedoussis G, Yu C, Tham YC, Lim B, Lim SH, Froguel P, Balkau B, Fink NR, Vinding RK, Sevelsted A, Bisgaard H, Coltell O, Dallongeville J, Gottrand F, Pahkala K, Niinikoski H, Hyppönen E, Pedersen O, März W, Inskip H, Jaddoe VWV, Dennison E, Wong TY, Sabanayagam C, Tai ES, Mohlke KL, Mackey DA, Gruszfeld D, Deloukas P, Tucker KL, Fumeron F, Bønnelykke K, Rossing P, Estruch R, Ordovas JM, Arnett DK, Meirhaeghe A, Amouyel P, Cheng CY, Sim X, Teo YY, van Dam RM, Koh WP, Orho-Melander M, Loeffler M, Kubo M, Thiery J, Mook-Kanamori DO, Mozaffarian D, Psaty BM, Franco OH, Wu T, North KE, Davey Smith G, Chavarro JE, Chasman DI, Qi L.

JAMA Netw Open. 2019 Sep 4;2(9):e1910915. doi: 10.1001/jamanetworkopen.2019.10915.

34.

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity.

Bradfield JP, Vogelezang S, Felix JF, Chesi A, Helgeland Ø, Horikoshi M, Karhunen V, Lowry E, Cousminer DL, Ahluwalia TS, Thiering E, Boh ET, Zafarmand MH, Vilor-Tejedor N, Wang CA, Joro R, Chen Z, Gauderman WJ, Pitkänen N, Parra EJ, Fernandez-Rhodes L, Alyass A, Monnereau C, Curtin JA, Have CT, McCormack SE, Hollensted M, Frithioff-Bøjsøe C, Valladares-Salgado A, Peralta-Romero J, Teo YY, Standl M, Leinonen JT, Holm JC, Peters T, Vioque J, Vrijheid M, Simpson A, Custovic A, Vaudel M, Canouil M, Lindi V, Atalay M, Kähönen M, Raitakari OT, van Schaik BDC, Berkowitz RI, Cole SA, Voruganti VS, Wang Y, Highland HM, Comuzzie AG, Butte NF, Justice AE, Gahagan S, Blanco E, Lehtimäki T, Lakka TA, Hebebrand J, Bonnefond A, Grarup N, Froguel P, Lyytikäinen LP, Cruz M, Kobes S, Hanson RL, Zemel BS, Hinney A, Teo KK, Meyre D, North KE, Gilliland FD, Bisgaard H, Bustamante M, Bonnelykke K, Pennell CE, Rivadeneira F, Uitterlinden AG, Baier LJ, Vrijkotte TGM, Heinrich J, Sørensen TIA, Saw SM, Pedersen O, Hansen T, Eriksson J, Widén E, McCarthy MI, Njølstad PR, Power C, Hyppönen E, Sebert S, Brown CD, Järvelin MR, Timpson NJ, Johansson S, Hakonarson H, Jaddoe VWV; Early Growth Genetics Consortium, Grant SFA.

Hum Mol Genet. 2019 Oct 1;28(19):3327-3338. doi: 10.1093/hmg/ddz161.

PMID:
31504550
35.

Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis.

Viitasalo A, Schnurr TM, Pitkänen N, Hollensted M, Nielsen TRH, Pahkala K, Atalay M, Lind MV, Heikkinen S, Frithioff-Bøjsøe C, Fonvig CE, Grarup N, Kähönen M, Carrasquilla GD, Larnkjaer A, Pedersen O, Michaelsen KF, Lakka TA, Holm JC, Lehtimäki T, Raitakari O, Hansen T, Kilpeläinen TO.

Am J Clin Nutr. 2019 Nov 1;110(5):1079-1087. doi: 10.1093/ajcn/nqz187.

PMID:
31504107
36.

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.

Spracklen CN, Karaderi T, Yaghootkar H, Schurmann C, Fine RS, Kutalik Z, Preuss MH, Lu Y, Wittemans LBL, Adair LS, Allison M, Amin N, Auer PL, Bartz TM, Blüher M, Boehnke M, Borja JB, Bork-Jensen J, Broer L, Chasman DI, Chen YI, Chirstofidou P, Demirkan A, van Duijn CM, Feitosa MF, Garcia ME, Graff M, Grallert H, Grarup N, Guo X, Haesser J, Hansen T, Harris TB, Highland HM, Hong J, Ikram MA, Ingelsson E, Jackson R, Jousilahti P, Kähönen M, Kizer JR, Kovacs P, Kriebel J, Laakso M, Lange LA, Lehtimäki T, Li J, Li-Gao R, Lind L, Luan J, Lyytikäinen LP, MacGregor S, Mackey DA, Mahajan A, Mangino M, Männistö S, McCarthy MI, McKnight B, Medina-Gomez C, Meigs JB, Molnos S, Mook-Kanamori D, Morris AP, de Mutsert R, Nalls MA, Nedeljkovic I, North KE, Pennell CE, Pradhan AD, Province MA, Raitakari OT, Raulerson CK, Reiner AP, Ridker PM, Ripatti S, Roberston N, Rotter JI, Salomaa V, Sandoval-Zárate AA, Sitlani CM, Spector TD, Strauch K, Stumvoll M, Taylor KD, Thuesen B, Tönjes A, Uitterlinden AG, Venturini C, Walker M, Wang CA, Wang S, Wareham NJ, Willems SM, Willems van Dijk K, Wilson JG, Wu Y, Yao J, Young KL, Langenberg C, Frayling TM, Kilpeläinen TO, Lindgren CM, Loos RJF, Mohlke KL.

Am J Hum Genet. 2019 Sep 5;105(3):670-671. doi: 10.1016/j.ajhg.2019.08.001. No abstract available.

37.

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration.

Liu X, Helenius D, Skotte L, Beaumont RN, Wielscher M, Geller F, Juodakis J, Mahajan A, Bradfield JP, Lin FTJ, Vogelezang S, Bustamante M, Ahluwalia TS, Pitkänen N, Wang CA, Bacelis J, Borges MC, Zhang G, Bedell BA, Rossi RM, Skogstrand K, Peng S, Thompson WK, Appadurai V, Lawlor DA, Kalliala I, Power C, McCarthy MI, Boyd HA, Marazita ML, Hakonarson H, Hayes MG, Scholtens DM, Rivadeneira F, Jaddoe VWV, Vinding RK, Bisgaard H, Knight BA, Pahkala K, Raitakari O, Helgeland Ø, Johansson S, Njølstad PR, Fadista J, Schork AJ, Nudel R, Miller DE, Chen X, Weirauch MT, Mortensen PB, Børglum AD, Nordentoft M, Mors O, Hao K, Ryckman KK, Hougaard DM, Kottyan LC, Pennell CE, Lyytikainen LP, Bønnelykke K, Vrijheid M, Felix JF, Lowe WL Jr, Grant SFA, Hyppönen E, Jacobsson B, Jarvelin MR, Muglia LJ, Murray JC, Freathy RM, Werge TM, Melbye M, Buil A, Feenstra B.

Nat Commun. 2019 Sep 2;10(1):3927. doi: 10.1038/s41467-019-11881-8.

38.

CVD risk factors and surrogate markers - Urban-rural differences.

Nuotio J, Vähämurto L, Pahkala K, Magnussen CG, Hutri-Kähönen N, Kähönen M, Laitinen T, Taittonen L, Tossavainen P, Lehtimäki T, Jokinen E, Viikari JSA, Raitakari O, Juonala M.

Scand J Public Health. 2019 Aug 29:1403494819869816. doi: 10.1177/1403494819869816. [Epub ahead of print]

PMID:
31464561
39.

Exposure to heavy physical work from early to later adulthood and primary healthcare visits due to musculoskeletal diseases in midlife: a register linked study.

Halonen JI, Shiri R, Mänty M, Sumanen H, Solovieva S, Viikari-Juntura E, Kähönen M, Lehtimäki T, Raitakari OT, Lallukka T.

BMJ Open. 2019 Aug 27;9(8):e031564. doi: 10.1136/bmjopen-2019-031564.

40.

Predicting overweight and obesity in young adulthood from childhood body-mass index: comparison of cutoffs derived from longitudinal and cross-sectional data.

Kartiosuo N, Ramakrishnan R, Lemeshow S, Juonala M, Burns TL, Woo JG, Jacobs DR Jr, Daniels SR, Venn A, Steinberger J, Urbina EM, Bazzano L, Sabin MA, Hu T, Prineas RJ, Sinaiko AR, Pahkala K, Raitakari O, Dwyer T.

Lancet Child Adolesc Health. 2019 Nov;3(11):795-802. doi: 10.1016/S2352-4642(19)30204-4. Epub 2019 Aug 23.

PMID:
31451394
41.

Potential Interplay between Dietary Saturated Fats and Genetic Variants of the NLRP3 Inflammasome to Modulate Insulin Resistance and Diabetes Risk: Insights from a Meta-Analysis of 19 005 Individuals.

Murphy AM, Smith CE, Murphy LM, Follis JL, Tanaka T, Richardson K, Noordam R, Lemaitre RN, Kähönen M, Dupuis J, Voortman T, Marouli E, Mook-Kanamori DO, Raitakari OT, Hong J, Dehghan A, Dedoussis G, de Mutsert R, Lehtimäki T, Liu CT, Rivadeneira F, Deloukas P, Mikkilä V, Meigs JB, Uitterlinden A, Ikram MA, Franco OH, Hughes M, O' Gaora P, Ordovás JM, Roche HM.

Mol Nutr Food Res. 2019 Nov;63(22):e1900226. doi: 10.1002/mnfr.201900226. Epub 2019 Sep 12.

42.

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM.

Nat Commun. 2019 Aug 14;10(1):3669. doi: 10.1038/s41467-019-11558-2.

43.

Natural History of Atherosclerosis and Abdominal Aortic Intima-Media Thickness: Rationale, Evidence, and Best Practice for Detection of Atherosclerosis in the Young.

Skilton MR, Celermajer DS, Cosmi E, Crispi F, Gidding SS, Raitakari OT, Urbina EM.

J Clin Med. 2019 Aug 12;8(8). pii: E1201. doi: 10.3390/jcm8081201. Review.

44.

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders.

Evangelou E, Gao H, Chu C, Ntritsos G, Blakeley P, Butts AR, Pazoki R, Suzuki H, Koskeridis F, Yiorkas AM, Karaman I, Elliott J, Luo Q, Aeschbacher S, Bartz TM, Baumeister SE, Braund PS, Brown MR, Brody JA, Clarke TK, Dimou N, Faul JD, Homuth G, Jackson AU, Kentistou KA, Joshi PK, Lemaitre RN, Lind PA, Lyytikäinen LP, Mangino M, Milaneschi Y, Nelson CP, Nolte IM, Perälä MM, Polasek O, Porteous D, Ratliff SM, Smith JA, Stančáková A, Teumer A, Tuominen S, Thériault S, Vangipurapu J, Whitfield JB, Wood A, Yao J, Yu B, Zhao W, Arking DE, Auvinen J, Liu C, Männikkö M, Risch L, Rotter JI, Snieder H, Veijola J, Blakemore AI, Boehnke M, Campbell H, Conen D, Eriksson JG, Grabe HJ, Guo X, van der Harst P, Hartman CA, Hayward C, Heath AC, Jarvelin MR, Kähönen M, Kardia SLR, Kühne M, Kuusisto J, Laakso M, Lahti J, Lehtimäki T, McIntosh AM, Mohlke KL, Morrison AC, Martin NG, Oldehinkel AJ, Penninx BWJH, Psaty BM, Raitakari OT, Rudan I, Samani NJ, Scott LJ, Spector TD, Verweij N, Weir DR, Wilson JF, Levy D, Tzoulaki I, Bell JD, Matthews PM, Rothenfluh A, Desrivières S, Schumann G, Elliott P.

Nat Hum Behav. 2019 Sep;3(9):950-961. doi: 10.1038/s41562-019-0653-z. Epub 2019 Jul 29.

PMID:
31358974
45.

Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents.

Viitasalo A, Schnurr TM, Pitkänen N, Hollensted M, Nielsen TRH, Pahkala K, Lintu N, Lind MV, Atalay M, Frithioff-Bøjsøe C, Fonvig CE, Grarup N, Kähönen M, Larnkjaer A, Pedersen O, Holm JC, Michaelsen KF, Lakka TA, Lehtimäki T, Raitakari O, Hansen T, Kilpeläinen TO.

Int J Obes (Lond). 2019 Oct;43(10):2007-2016. doi: 10.1038/s41366-019-0414-0. Epub 2019 Jul 22.

PMID:
31332278
46.

New evidence from plasma ceramides links apoE polymorphism to greater risk of coronary artery disease in Finnish adults.

Karjalainen JP, Mononen N, Hutri-Kähönen N, Lehtimäki M, Hilvo M, Kauhanen D, Juonala M, Viikari J, Kähönen M, Raitakari O, Laaksonen R, Lehtimäki T.

J Lipid Res. 2019 Sep;60(9):1622-1629. doi: 10.1194/jlr.M092809. Epub 2019 Jul 3.

PMID:
31270131
47.

Whole blood microRNA levels associate with glycemic status and correlate with target mRNAs in pathways important to type 2 diabetes.

Mononen N, Lyytikäinen LP, Seppälä I, Mishra PP, Juonala M, Waldenberger M, Klopp N, Illig T, Leiviskä J, Loo BM, Laaksonen R, Oksala N, Kähönen M, Hutri-Kähönen N, Raitakari O, Lehtimäki T, Raitoharju E.

Sci Rep. 2019 Jun 20;9(1):8887. doi: 10.1038/s41598-019-43793-4.

48.

Cognitive Decline Before and After Incident Coronary Heart Disease: Opportunity to Intervene Cognitive Function Trajectories.

Rovio SP, Pahkala K, Raitakari OT.

J Am Coll Cardiol. 2019 Jun 25;73(24):3051-3053. doi: 10.1016/j.jacc.2019.04.020. No abstract available.

PMID:
31221252
49.

Adverse childhood environment and self-reported sleep in adulthood: The Young Finns Study.

Talvitie E, Hintsanen M, Pulkki-Råback L, Lipsanen J, Merjonen P, Hakulinen C, Elovainio M, Rosenström T, Lehtimäki T, Raitakari O, Keltikangas-Järvinen L.

Health Psychol. 2019 Aug;38(8):705-715. doi: 10.1037/hea0000772. Epub 2019 Jun 20.

PMID:
31219257
50.

Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns.

Sliz E, Kalaoja M, Ahola-Olli A, Raitakari O, Perola M, Salomaa V, Lehtimäki T, Karhu T, Viinamäki H, Salmi M, Santalahti K, Jalkanen S, Jokelainen J, Keinänen-Kiukaanniemi S, Männikkö M, Herzig KH, Järvelin MR, Sebert S, Kettunen J.

J Med Genet. 2019 Sep;56(9):607-616. doi: 10.1136/jmedgenet-2018-105965. Epub 2019 Jun 19.

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