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Items: 1 to 50 of 79

1.

Intrahepatic Cholestasis Owing to a Novel Heterozygous ABCG8 Mutation and SLC4A2 Polymorphism With Favorable Outcome Under Ursodeoxycholic Acid.

Ciocan D, Voican CS, Barbu V, Corpechot C, Rainteau D, Prevot S, Lebrun A, Perlemuter G.

Am J Gastroenterol. 2019 Sep;114(9):1556-1559. doi: 10.14309/ajg.0000000000000328. No abstract available.

PMID:
31335361
2.

Variations in gastrointestinal lipases, pH and bile acid levels with food intake, age and diseases: Possible impact on oral lipid-based drug delivery systems.

Amara S, Bourlieu C, Humbert L, Rainteau D, Carrière F.

Adv Drug Deliv Rev. 2019 Mar 1;142:3-15. doi: 10.1016/j.addr.2019.03.005. Epub 2019 Mar 26. Review.

PMID:
30926476
3.

Saccharomyces boulardii CNCM I-745 Modulates the Fecal Bile Acids Metabolism During Antimicrobial Therapy in Healthy Volunteers.

Kelly CP, Chong Nguyen C, Palmieri LJ, Pallav K, Dowd SE, Humbert L, Seksik P, Bado A, Coffin B, Rainteau D, Kabbani T, Duboc H.

Front Microbiol. 2019 Mar 4;10:336. doi: 10.3389/fmicb.2019.00336. eCollection 2019.

4.

TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function.

Merlen G, Kahale N, Ursic-Bedoya J, Bidault-Jourdainne V, Simerabet H, Doignon I, Tanfin Z, Garcin I, Péan N, Gautherot J, Davit-Spraul A, Guettier C, Humbert L, Rainteau D, Ebnet K, Ullmer C, Cassio D, Tordjmann T.

Gut. 2019 Feb 5. pii: gutjnl-2018-316975. doi: 10.1136/gutjnl-2018-316975. [Epub ahead of print]

PMID:
30723104
5.

Predictive Value of Cellular Accumulation of Hydrophobic Bile Acids As a Marker of Cholestatic Drug Potential.

Burban A, Sharanek A, Humbert L, Eguether T, Guguen-Guillouzo C, Rainteau D, Guillouzo A.

Toxicol Sci. 2019 Apr 1;168(2):474-485. doi: 10.1093/toxsci/kfz009.

6.

Milk Polar Lipids in a High-Fat Diet Can Prevent Body Weight Gain: Modulated Abundance of Gut Bacteria in Relation with Fecal Loss of Specific Fatty Acids.

Milard M, Laugerette F, Durand A, Buisson C, Meugnier E, Loizon E, Louche-Pelissier C, Sauvinet V, Garnier L, Viel S, Bertrand K, Joffre F, Cheillan D, Humbert L, Rainteau D, Plaisancié P, Bindels LB, Neyrinck AM, Delzenne NM, Michalski MC.

Mol Nutr Food Res. 2019 Feb;63(4):e1801078. doi: 10.1002/mnfr.201801078. Epub 2019 Jan 25.

PMID:
30628158
7.

Diet-Induced Dysbiosis and Genetic Background Synergize With Cystic Fibrosis Transmembrane Conductance Regulator Deficiency to Promote Cholangiopathy in Mice.

Debray D, El Mourabit H, Merabtene F, Brot L, Ulveling D, Chrétien Y, Rainteau D, Moszer I, Wendum D, Sokol H, Housset C.

Hepatol Commun. 2018 Oct 10;2(12):1533-1549. doi: 10.1002/hep4.1266. eCollection 2018 Dec.

8.

Inhibitory Effect of Ursodeoxycholic Acid on Clostridium difficile Germination Is Insufficient to Prevent Colitis: A Study in Hamsters and Humans.

Palmieri LJ, Rainteau D, Sokol H, Beaugerie L, Dior M, Coffin B, Humbert L, Eguether T, Bado A, Hoys S, Janoir C, Duboc H.

Front Microbiol. 2018 Nov 22;9:2849. doi: 10.3389/fmicb.2018.02849. eCollection 2018.

9.

Antipruritic effect of bezafibrate and serum autotaxin measures in patients with primary biliary cholangitis.

Kremer AE, Le Cleac'h A, Lemoinne S, Wolf K, De Chaisemartin L, Chollet-Martin S, Humbert L, Rainteau D, Poupon R, Rousseau A, Chazouillères O, Corpechot C.

Gut. 2019 Oct;68(10):1902-1903. doi: 10.1136/gutjnl-2018-317426. Epub 2018 Sep 18. No abstract available.

PMID:
30228218
10.

Postprandial bile acid levels in intestine and plasma reveal altered biliary circulation in chronic pancreatitis patients.

Humbert L, Rainteau D, Tuvignon N, Wolf C, Seksik P, Laugier R, Carrière F.

J Lipid Res. 2018 Nov;59(11):2202-2213. doi: 10.1194/jlr.M084830. Epub 2018 Sep 11.

PMID:
30206181
11.

Inter-kingdom effect on epithelial cells of the N-Acyl homoserine lactone 3-oxo-C12:2, a major quorum-sensing molecule from gut microbiota.

Landman C, Grill JP, Mallet JM, Marteau P, Humbert L, Le Balc'h E, Maubert MA, Perez K, Chaara W, Brot L, Beaugerie L, Sokol H, Thenet S, Rainteau D, Seksik P, Quévrain E; Saint Antoine IBD Network.

PLoS One. 2018 Aug 29;13(8):e0202587. doi: 10.1371/journal.pone.0202587. eCollection 2018.

12.

Bile acid homeostasis and intestinal dysbiosis in alcoholic hepatitis.

Ciocan D, Voican CS, Wrzosek L, Hugot C, Rainteau D, Humbert L, Cassard AM, Perlemuter G.

Aliment Pharmacol Ther. 2018 Nov;48(9):961-974. doi: 10.1111/apt.14949. Epub 2018 Aug 24.

13.

Bilophila wadsworthia aggravates high fat diet induced metabolic dysfunctions in mice.

Natividad JM, Lamas B, Pham HP, Michel ML, Rainteau D, Bridonneau C, da Costa G, van Hylckama Vlieg J, Sovran B, Chamignon C, Planchais J, Richard ML, Langella P, Veiga P, Sokol H.

Nat Commun. 2018 Jul 18;9(1):2802. doi: 10.1038/s41467-018-05249-7.

14.

A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis.

Corpechot C, Chazouillères O, Rousseau A, Le Gruyer A, Habersetzer F, Mathurin P, Goria O, Potier P, Minello A, Silvain C, Abergel A, Debette-Gratien M, Larrey D, Roux O, Bronowicki JP, Boursier J, de Ledinghen V, Heurgue-Berlot A, Nguyen-Khac E, Zoulim F, Ollivier-Hourmand I, Zarski JP, Nkontchou G, Lemoinne S, Humbert L, Rainteau D, Lefèvre G, de Chaisemartin L, Chollet-Martin S, Gaouar F, Admane FH, Simon T, Poupon R.

N Engl J Med. 2018 Jun 7;378(23):2171-2181. doi: 10.1056/NEJMoa1714519.

15.

Roux-en-Y Gastric-Bypass and sleeve gastrectomy induces specific shifts of the gut microbiota without altering the metabolism of bile acids in the intestinal lumen.

Duboc H, Nguyen CC, Cavin JB, Ribeiro-Parenti L, Jarry AC, Rainteau D, Humbert L, Coffin B, Le Gall M, Bado A, Sokol H.

Int J Obes (Lond). 2019 Feb;43(2):428-431. doi: 10.1038/s41366-018-0015-3. Epub 2018 Jan 30.

PMID:
29453461
16.

The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease.

Torres J, Palmela C, Brito H, Bao X, Ruiqi H, Moura-Santos P, Pereira da Silva J, Oliveira A, Vieira C, Perez K, Itzkowitz SH, Colombel JF, Humbert L, Rainteau D, Cravo M, Rodrigues CM, Hu J.

United European Gastroenterol J. 2018 Feb;6(1):112-122. doi: 10.1177/2050640617708953. Epub 2017 May 5.

17.

Plasma oxysterols: biomarkers for diagnosis and treatment in spastic paraplegia type 5.

Marelli C, Lamari F, Rainteau D, Lafourcade A, Banneau G, Humbert L, Monin ML, Petit E, Debs R, Castelnovo G, Ollagnon E, Lavie J, Pilliod J, Coupry I, Babin PJ, Guissart C, Benyounes I, Ullmann U, Lesca G, Thauvin-Robinet C, Labauge P, Odent S, Ewenczyk C, Wolf C, Stevanin G, Hajage D, Durr A, Goizet C, Mochel F.

Brain. 2018 Jan 1;141(1):72-84. doi: 10.1093/brain/awx297.

PMID:
29228183
18.

Progressive and Preferential Cellular Accumulation of Hydrophobic Bile Acids Induced by Cholestatic Drugs Is Associated with Inhibition of Their Amidation and Sulfation.

Sharanek A, Burban A, Humbert L, Guguen-Guillouzo C, Rainteau D, Guillouzo A.

Drug Metab Dispos. 2017 Dec;45(12):1292-1303. doi: 10.1124/dmd.117.077420. Epub 2017 Sep 19.

PMID:
28928138
19.

Glycerolipid analysis during desiccation and recovery of the resurrection plant Xerophyta humilis (Bak) Dur and Schinz.

Tshabuse F, Farrant JM, Humbert L, Moura D, Rainteau D, Espinasse C, Idrissi A, Merlier F, Acket S, Rafudeen MS, Thomasset B, Ruelland E.

Plant Cell Environ. 2018 Mar;41(3):533-547. doi: 10.1111/pce.13063. Epub 2017 Nov 10.

PMID:
28865108
20.

Chenodeoxycholic acid stimulated fibroblast growth factor 19 response - a potential biochemical test for bile acid diarrhoea.

Borup C, Wildt S, Rumessen JJ, Bouchelouche PN, Graff J, Damgaard M, McQuitty C, Rainteau D, Munck LK.

Aliment Pharmacol Ther. 2017 Jun;45(11):1433-1442. doi: 10.1111/apt.14056. Epub 2017 Apr 5.

21.

Bile acids and their receptors during liver regeneration: "Dangerous protectors".

Merlen G, Ursic-Bedoya J, Jourdainne V, Kahale N, Glenisson M, Doignon I, Rainteau D, Tordjmann T.

Mol Aspects Med. 2017 Aug;56:25-33. doi: 10.1016/j.mam.2017.03.002. Epub 2017 Mar 23. Review.

PMID:
28302491
22.

Long-Term Evaluation of Biliary Reflux After Experimental One-Anastomosis Gastric Bypass in Rats.

Bruzzi M, Duboc H, Gronnier C, Rainteau D, Couvelard A, Le Gall M, Bado A, Chevallier JM.

Obes Surg. 2017 Apr;27(4):1119-1122. doi: 10.1007/s11695-017-2577-x.

PMID:
28205007
23.

Fecal microbiota manipulation prevents dysbiosis and alcohol-induced liver injury in mice.

Ferrere G, Wrzosek L, Cailleux F, Turpin W, Puchois V, Spatz M, Ciocan D, Rainteau D, Humbert L, Hugot C, Gaudin F, Noordine ML, Robert V, Berrebi D, Thomas M, Naveau S, Perlemuter G, Cassard AM.

J Hepatol. 2017 Apr;66(4):806-815. doi: 10.1016/j.jhep.2016.11.008. Epub 2016 Nov 25.

PMID:
27890791
24.

Lysophosphatidylcholine acyltransferase 1 is downregulated by hepatitis C virus: impact on production of lipo-viro-particles.

Beilstein F, Lemasson M, Pène V, Rainteau D, Demignot S, Rosenberg AR.

Gut. 2017 Dec;66(12):2160-2169. doi: 10.1136/gutjnl-2016-311508. Epub 2016 Aug 31.

PMID:
27582510
25.

The P2X4 purinergic receptor impacts liver regeneration after partial hepatectomy in mice through the regulation of biliary homeostasis.

Besnard A, Gautherot J, Julien B, Tebbi A, Garcin I, Doignon I, Péan N, Gonzales E, Cassio D, Grosse B, Liu B, Safya H, Cauchois F, Humbert L, Rainteau D, Tordjmann T.

Hepatology. 2016 Sep;64(3):941-53. doi: 10.1002/hep.28675. Epub 2016 Jul 15.

PMID:
27301647
26.

Interplay between bile acid metabolism and microbiota in irritable bowel syndrome.

Dior M, Delagrèverie H, Duboc H, Jouet P, Coffin B, Brot L, Humbert L, Trugnan G, Seksik P, Sokol H, Rainteau D, Sabate JM.

Neurogastroenterol Motil. 2016 Sep;28(9):1330-40. doi: 10.1111/nmo.12829. Epub 2016 Apr 5.

PMID:
27060367
27.

Arabidopsis non-specific phospholipase C1: characterization and its involvement in response to heat stress.

Krčková Z, Brouzdová J, Daněk M, Kocourková D, Rainteau D, Ruelland E, Valentová O, Pejchar P, Martinec J.

Front Plant Sci. 2015 Nov 4;6:928. doi: 10.3389/fpls.2015.00928. eCollection 2015.

28.

Microorganisms linked to inflammatory bowel disease-associated dysbiosis differentially impact host physiology in gnotobiotic mice.

Hoffmann TW, Pham HP, Bridonneau C, Aubry C, Lamas B, Martin-Gallausiaux C, Moroldo M, Rainteau D, Lapaque N, Six A, Richard ML, Fargier E, Le Guern ME, Langella P, Sokol H.

ISME J. 2016 Feb;10(2):460-77. doi: 10.1038/ismej.2015.127. Epub 2015 Jul 28.

29.

Cellular Accumulation and Toxic Effects of Bile Acids in Cyclosporine A-Treated HepaRG Hepatocytes.

Sharanek A, Burban A, Humbert L, Bachour-El Azzi P, Felix-Gomes N, Rainteau D, Guillouzo A.

Toxicol Sci. 2015 Oct;147(2):573-87. doi: 10.1093/toxsci/kfv155. Epub 2015 Jul 20.

PMID:
26198044
30.

The Bile Acid Receptor TGR5 and Liver Regeneration.

Jourdainne V, Péan N, Doignon I, Humbert L, Rainteau D, Tordjmann T.

Dig Dis. 2015;33(3):319-26. doi: 10.1159/000371668. Epub 2015 May 27.

PMID:
26045264
31.

Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn's disease.

Quévrain E, Maubert MA, Michon C, Chain F, Marquant R, Tailhades J, Miquel S, Carlier L, Bermúdez-Humarán LG, Pigneur B, Lequin O, Kharrat P, Thomas G, Rainteau D, Aubry C, Breyner N, Afonso C, Lavielle S, Grill JP, Chassaing G, Chatel JM, Trugnan G, Xavier R, Langella P, Sokol H, Seksik P.

Gut. 2016 Mar;65(3):415-425. doi: 10.1136/gutjnl-2014-307649. Epub 2015 Jun 4.

32.

Improvements in glucose metabolism early after gastric bypass surgery are not explained by increases in total bile acids and fibroblast growth factor 19 concentrations.

Jørgensen NB, Dirksen C, Bojsen-Møller KN, Kristiansen VB, Wulff BS, Rainteau D, Humbert L, Rehfeld JF, Holst JJ, Madsbad S, Clausen TR.

J Clin Endocrinol Metab. 2015 Mar;100(3):E396-406. doi: 10.1210/jc.2014-1658. Epub 2014 Dec 23.

PMID:
25536209
33.

Long-term effects of Roux-en-Y gastric bypass on postprandial plasma lipid and bile acids kinetics in female non diabetic subjects: A cross-sectional pilot study.

De Giorgi S, Campos V, Egli L, Toepel U, Carrel G, Cariou B, Rainteau D, Schneiter P, Tappy L, Giusti V.

Clin Nutr. 2015 Oct;34(5):911-7. doi: 10.1016/j.clnu.2014.09.018. Epub 2014 Sep 26.

PMID:
25306425
34.

Different dose-dependent mechanisms are involved in early cyclosporine a-induced cholestatic effects in hepaRG cells.

Sharanek A, Azzi PB, Al-Attrache H, Savary CC, Humbert L, Rainteau D, Guguen-Guillouzo C, Guillouzo A.

Toxicol Sci. 2014 Sep;141(1):244-53. doi: 10.1093/toxsci/kfu122. Epub 2014 Jun 27.

35.

MYO5B and bile salt export pump contribute to cholestatic liver disorder in microvillous inclusion disease.

Girard M, Lacaille F, Verkarre V, Mategot R, Feldmann G, Grodet A, Sauvat F, Irtan S, Davit-Spraul A, Jacquemin E, Ruemmele F, Rainteau D, Goulet O, Colomb V, Chardot C, Henrion-Caude A, Debray D.

Hepatology. 2014 Jul;60(1):301-10. doi: 10.1002/hep.26974. Epub 2014 May 27.

PMID:
24375397
36.

Lipids in metabolic diseases.

Dugail I, Kalopissis A, Miquel M, Rainteau D, Zachowski A, Forest C.

Biochimie. 2014 Jan;96:1-2. doi: 10.1016/j.biochi.2013.11.009. No abstract available.

PMID:
24321080
37.

High-resolution mass spectrometry and partial de novo sequencing constitute a useful approach for determining the profile of chemokine secretion following the stimulation of human intestinal epithelial cells.

Maubert MA, Quévrain E, Capton E, Grill JP, Thomas G, Bachelet M, Rainteau D, Trugnan G, Tabet JC, Masliah J, Afonso C.

Rapid Commun Mass Spectrom. 2013 Oct 15;27(19):2179-87. doi: 10.1002/rcm.6680.

PMID:
23996391
38.

Vitamin D nuclear receptor deficiency promotes cholestatic liver injury by disruption of biliary epithelial cell junctions in mice.

Firrincieli D, Zúñiga S, Rey C, Wendum D, Lasnier E, Rainteau D, Braescu T, Falguières T, Boissan M, Cadoret A, Housset C, Chignard N.

Hepatology. 2013 Oct;58(4):1401-12. doi: 10.1002/hep.26453. Epub 2013 Sep 6.

39.

The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice.

Péan N, Doignon I, Garcin I, Besnard A, Julien B, Liu B, Branchereau S, Spraul A, Guettier C, Humbert L, Schoonjans K, Rainteau D, Tordjmann T.

Hepatology. 2013 Oct;58(4):1451-60. doi: 10.1002/hep.26463. Epub 2013 Aug 19.

PMID:
23686672
40.

Multiple reaction monitoring mass spectrometry is a powerful tool to study glycerolipid composition in plants with different level of desaturase activity.

Djafi N, Humbert L, Rainteau D, Cantrel C, Zachowski A, Ruelland E.

Plant Signal Behav. 2013 May;8(5):e24118. doi: 10.4161/psb.24118. Epub 2013 Mar 7.

41.

Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases.

Duboc H, Rajca S, Rainteau D, Benarous D, Maubert MA, Quervain E, Thomas G, Barbu V, Humbert L, Despras G, Bridonneau C, Dumetz F, Grill JP, Masliah J, Beaugerie L, Cosnes J, Chazouillères O, Poupon R, Wolf C, Mallet JM, Langella P, Trugnan G, Sokol H, Seksik P.

Gut. 2013 Apr;62(4):531-9. doi: 10.1136/gutjnl-2012-302578. Epub 2012 Sep 19.

PMID:
22993202
42.

Acyl chains of phospholipase D transphosphatidylation products in Arabidopsis cells: a study using multiple reaction monitoring mass spectrometry.

Rainteau D, Humbert L, Delage E, Vergnolle C, Cantrel C, Maubert MA, Lanfranchi S, Maldiney R, Collin S, Wolf C, Zachowski A, Ruelland E.

PLoS One. 2012;7(7):e41985. doi: 10.1371/journal.pone.0041985. Epub 2012 Jul 25.

43.

Bile acid profiling in human biological samples: comparison of extraction procedures and application to normal and cholestatic patients.

Humbert L, Maubert MA, Wolf C, Duboc H, Mahé M, Farabos D, Seksik P, Mallet JM, Trugnan G, Masliah J, Rainteau D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Jun 15;899:135-45. doi: 10.1016/j.jchromb.2012.05.015. Epub 2012 May 17.

PMID:
22664055
44.

Crosstalk between the hepatologist and the cardiologist: a future place for the lithocholic acid as a coronary atheroma risk factor?

Duboc H, Aelion H, Rainteau D, Rajca S, Sokol H, Humbert L, Farabos D, Coffin B, Weber S, Porcher R, Varenne O, Duboc D.

Hepatology. 2012 Dec;56(6):2426. doi: 10.1002/hep.25839. No abstract available.

PMID:
22605482
45.

Defects in gallbladder emptying and bile Acid homeostasis in mice with cystic fibrosis transmembrane conductance regulator deficiencies.

Debray D, Rainteau D, Barbu V, Rouahi M, El Mourabit H, Lerondel S, Rey C, Humbert L, Wendum D, Cottart CH, Dawson P, Chignard N, Housset C.

Gastroenterology. 2012 Jun;142(7):1581-91.e6. doi: 10.1053/j.gastro.2012.02.033. Epub 2012 Feb 24.

46.

Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome.

Duboc H, Rainteau D, Rajca S, Humbert L, Farabos D, Maubert M, Grondin V, Jouet P, Bouhassira D, Seksik P, Sokol H, Coffin B, Sabaté JM.

Neurogastroenterol Motil. 2012 Jun;24(6):513-20, e246-7. doi: 10.1111/j.1365-2982.2012.01893.x. Epub 2012 Feb 22.

PMID:
22356587
47.

High plasma level of nucleocapsid-free envelope glycoprotein-positive lipoproteins in hepatitis C patients.

Scholtes C, Ramière C, Rainteau D, Perrin-Cocon L, Wolf C, Humbert L, Carreras M, Guironnet-Paquet A, Zoulim F, Bartenschlager R, Lotteau V, André P, Diaz O.

Hepatology. 2012 Jul;56(1):39-48. doi: 10.1002/hep.25628. Epub 2012 Apr 25.

PMID:
22290760
48.

Protoporphyrin retention in hepatocytes and Kupffer cells prevents sclerosing cholangitis in erythropoietic protoporphyria mouse model.

Lyoumi S, Abitbol M, Rainteau D, Karim Z, Bernex F, Oustric V, Millot S, Lettéron P, Heming N, Guillmot L, Montagutelli X, Berdeaux G, Gouya L, Poupon R, Deybach JC, Beaumont C, Puy H.

Gastroenterology. 2011 Oct;141(4):1509-19, 1519.e1-3. doi: 10.1053/j.gastro.2011.06.078. Epub 2011 Jul 14.

PMID:
21762662
49.

Trade-off between bile resistance and nutritional competence drives Escherichia coli diversification in the mouse gut.

De Paepe M, Gaboriau-Routhiau V, Rainteau D, Rakotobe S, Taddei F, Cerf-Bensussan N.

PLoS Genet. 2011 Jun;7(6):e1002107. doi: 10.1371/journal.pgen.1002107. Epub 2011 Jun 16.

50.

Immediate neuroendocrine signaling after partial hepatectomy through acute portal hyperpressure and cholestasis.

Doignon I, Julien B, Serrière-Lanneau V, Garcin I, Alonso G, Nicou A, Monnet F, Gigou M, Humbert L, Rainteau D, Azoulay D, Castaing D, Gillon MC, Samuel D, Duclos-Vallée JC, Tordjmann T.

J Hepatol. 2011 Mar;54(3):481-8. doi: 10.1016/j.jhep.2010.07.012. Epub 2010 Sep 22.

PMID:
21163545

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