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Items: 26

1.

L-Methylfolate Calcium Supplementation in Adolescents and Children: A Retrospective Analysis.

Rainka M, Aladeen T, Westphal E, Meaney J, Gengo F, Greger J, Capote H.

J Psychiatr Pract. 2019 Jul;25(4):258-267. doi: 10.1097/PRA.0000000000000400.

PMID:
31291206
2.

Prospective Determination of Aspirin Sensitivity in Patients Resistant to Low Dose Aspirin: A Proof of Concept Study.

Westphal ES, Rainka M, Amsler M, Aladeen T, Wisniewski C, Bates V, Gengo FM.

J Clin Pharmacol. 2018 Sep;58(9):1157-1163. doi: 10.1002/jcph.1259. Epub 2018 May 18.

PMID:
29775206
3.

The Development of an In Vitro Assay for the Prospective Determination of Aspirin Sensitivity.

Westphal ES, Wisniewski C, Rainka M, Smith NM, Bates V, Gengo FM.

J Clin Pharmacol. 2018 Sep;58(9):1150-1156. doi: 10.1002/jcph.1260. Epub 2018 May 18.

PMID:
29775202
4.

Discovery of a highly potent orally bioavailable imidazo-[1, 2-a]pyrazine Aurora inhibitor.

Yu T, Zhang Y, Kerekes AD, Tagat JR, Doll RJ, Xiao Y, Esposite S, Hruza A, Belanger DB, Voss M, Rainka MP, Basso A, Liu M, Liang L, Sui N, Prelusky D, Rindgen D, Zhang L.

Bioorg Med Chem Lett. 2018 May 1;28(8):1397-1403. doi: 10.1016/j.bmcl.2018.02.037. Epub 2018 Feb 23.

PMID:
29545102
5.

Evaluating the Effect of Six Proton Pump Inhibitors on the Antiplatelet Effects of Clopidogrel.

Przespolewski ER, Westphal ES, Rainka M, Smith NM, Bates V, Gengo FM.

J Stroke Cerebrovasc Dis. 2018 Jun;27(6):1582-1589. doi: 10.1016/j.jstrokecerebrovasdis.2018.01.011. Epub 2018 Feb 12.

PMID:
29449127
6.

The use of brexpiprazole amongst individuals with insufficient outcomes with aripiprazole or bupropion: A case series.

Aladeen T, Westphal E, Lee Y, Rong C, Rainka M, Capote H, McIntyre RS.

Perspect Psychiatr Care. 2018 Oct;54(4):507-513. doi: 10.1111/ppc.12258. Epub 2018 Feb 10.

PMID:
29427512
7.

Ropinirole in Bipolar Disorder: Rate of Manic Switching and Change in Disease Severity.

Capote HA, Rainka M, Westphal ES, Beecher J, Gengo FM.

Perspect Psychiatr Care. 2018 Apr;54(2):100-106. doi: 10.1111/ppc.12205. Epub 2017 Jan 20.

PMID:
28105645
8.

Topical diclofenac does not affect the antiplatelet properties of aspirin as compared to the intermediate effects of oral diclofenac: A prospective, randomized, complete crossover study.

Rowcliffe M, Nezami B, Westphal ES, Rainka M, Janda M, Bates V, Gengo F.

J Clin Pharmacol. 2016 Apr;56(4):422-8. doi: 10.1002/jcph.615. Epub 2015 Nov 5.

PMID:
26265197
9.

Platelet response to increased aspirin dose in patients with persistent platelet aggregation while treated with aspirin 81 mg.

Gengo F, Westphal ES, Rainka MM, Janda M, Robson MJ, Hourihane JM, Bates V.

J Clin Pharmacol. 2016 Apr;56(4):414-21. doi: 10.1002/jcph.608. Epub 2015 Oct 26.

PMID:
26239393
10.

A phase 2a, randomized, crossover trial of gabapentin enacarbil for the treatment of postherpetic neuralgia in gabapentin inadequate responders.

Harden RN, Freeman R, Rainka M, Zhang L, Bell C, Berges A, Chen C, Graff O, Harding K, Hunter S, Kavanagh S, Schwartzbach C, Warren S, McClung C.

Pain Med. 2013 Dec;14(12):1918-32. doi: 10.1111/pme.12227. Epub 2013 Sep 18.

PMID:
24102928
11.

Highly selective electrocatalytic dehydrogenation at low applied potential catalyzed by an Ir organometallic complex.

Bonitatibus PJ Jr, Rainka MP, Peters AJ, Simone DL, Doherty MD.

Chem Commun (Camb). 2013 Nov 21;49(90):10581-3. doi: 10.1039/c3cc46051g.

PMID:
24091876
12.

A randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of gabapentin enacarbil in subjects with neuropathic pain associated with postherpetic neuralgia (PXN110748).

Zhang L, Rainka M, Freeman R, Harden RN, Bell CF, Chen C, Graff O, Harding K, Hunter S, Kavanagh S, Laurijssens B, Schwartzbach C, Warren S, McClung C.

J Pain. 2013 Jun;14(6):590-603. doi: 10.1016/j.jpain.2013.01.768. Epub 2013 Apr 18.

PMID:
23602345
13.

Pharmacokinetic simulation of fatal carbamazepine intoxication in 23-month old child following phenytoin discontinuation.

Venci JV, Rowcliffe MM, Wollenberg L, Rainka MM, Gengo FM.

Forensic Sci Med Pathol. 2013 Mar;9(1):73-6. doi: 10.1007/s12024-012-9373-7. Epub 2012 Aug 23.

PMID:
22915321
14.

Synthesis and SAR studies of imidazo-[1,2-a]-pyrazine Aurora kinase inhibitors with improved off-target kinase selectivity.

Voss ME, Rainka MP, Fleming M, Peterson LH, Belanger DB, Siddiqui MA, Hruza A, Voigt J, Gray K, Basso AD.

Bioorg Med Chem Lett. 2012 May 15;22(10):3544-9. doi: 10.1016/j.bmcl.2012.03.051. Epub 2012 Mar 21.

PMID:
22503250
15.

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.

Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM; Alzheimer's Disease Neuroimaging Initiative; Pediatric Imaging, Neurocognition, and Genetics Study, Weiner M, Aisen P, Petersen R, Jack CR Jr, Jagust W, Trojanowki JQ, Toga AW, Beckett L, Green RC, Saykin AJ, Morris J, Liu E, Montine T, Gamst A, Thomas RG, Donohue M, Walter S, Gessert D, Sather T, Harvey D, Kornak J, Dale A, Bernstein M, Felmlee J, Fox N, Thompson P, Schuff N, Alexander G, DeCarli C, Bandy D, Koeppe RA, Foster N, Reiman EM, Chen K, Mathis C, Cairns NJ, Taylor-Reinwald L, Trojanowki JQ, Shaw L, Lee VM, Korecka M, Crawford K, Neu S, Foroud TM, Potkin S, Shen L, Kachaturian Z, Frank R, Snyder PJ, Molchan S, Kaye J, Quinn J, Lind B, Dolen S, Schneider LS, Pawluczyk S, Spann BM, Brewer J, Vanderswag H, Heidebrink JL, Lord JL, Johnson K, Doody RS, Villanueva-Meyer J, Chowdhury M, Stern Y, Honig LS, Bell KL, Morris JC, Ances B, Carroll M, Leon S, Mintun MA, Schneider S, Marson D, Griffith R, Clark D, Grossman H, Mitsis E, Romirowsky A, deToledo-Morrell L, Shah RC, Duara R, Varon D, Roberts P, Albert M, Onyike C, Kielb S, Rusinek H, de Leon MJ, Glodzik L, De Santi S, Doraiswamy PM, Petrella JR, Coleman RE, Arnold SE, Karlawish JH, Wolk D, Smith CD, Jicha G, Hardy P, Lopez OL, Oakley M, Simpson DM, Porsteinsson AP, Goldstein BS, Martin K, Makino KM, Ismail MS, Brand C, Mulnard RA, Thai G, Mc-Adams-Ortiz C, Womack K, Mathews D, Quiceno M, Diaz-Arrastia R, King R, Weiner M, Martin-Cook K, DeVous M, Levey AI, Lah JJ, Cellar JS, Burns JM, Anderson HS, Swerdlow RH, Apostolova L, Lu PH, Bartzokis G, Silverman DH, Graff-Radford NR, Parfitt F, Johnson H, Farlow MR, Hake AM, Matthews BR, Herring S, van Dyck CH, Carson RE, MacAvoy MG, Chertkow H, Bergman H, Hosein C, Black S, Stefanovic B, Caldwell C, Ging-Yuek, Hsiung R, Feldman H, Mudge B, Assaly M, Kertesz A, Rogers J, Trost D, Bernick C, Munic D, Kerwin D, Mesulam MM, Lipowski K, Wu CK, Johnson N, Sadowsky C, Martinez W, Villena T, Turner RS, Johnson K, Reynolds B, Sperling RA, Johnson KA, Marshall G, Frey M, Yesavage J, Taylor JL, Lane B, Rosen A, Tinklenberg J, Sabbagh M, Belden C, Jacobson S, Kowall N, Killiany R, Budson AE, Norbash A, Johnson PL, Obisesan TO, Wolday S, Bwayo SK, Lerner A, Hudson L, Ogrocki P, Fletcher E, Carmichael O, Olichney J, Kittur S, Borrie M, Lee TY, Bartha R, Johnson S, Asthana S, Carlsson CM, Potkin SG, Preda A, Nguyen D, Tariot P, Fleisher A, Reeder S, Bates V, Capote H, Rainka M, Scharre DW, Kataki M, Zimmerman EA, Celmins D, Brown AD, Pearlson GD, Blank K, Anderson K, Santulli RB, Schwartz ES, Sink KM, Williamson JD, Garg P, Watkins F, Ott BR, Querfurth H, Tremont G, Salloway S, Malloy P, Correia S, Rosen HJ, Miller BL, Mintzer J, Longmire CF, Spicer K, Finger E, Rachinsky I, Drost D, Jernigan T, McCabe C, Grant E, Ernst T, Kuperman J, Chung Y, Murray S, Bloss C, Darst B, Pritchett L, Saito A, Amaral D, DiNino M, Eyngorina B, Sowell E, Houston S, Soderberg L, Kaufmann W, van Zijl P, Rizzo-Busack H, Javid M, Mehta N, Ruberry E, Powers A, Rosen B, Gebhard N, Manigan H, Frazier J, Kennedy D, Yakutis L, Hill M, Gruen J, Bosson-Heenan J, Carlson H.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3985-90. doi: 10.1073/pnas.1105829109. Epub 2012 Feb 16.

16.

Discovery of orally bioavailable imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors.

Belanger DB, Williams MJ, Curran PJ, Mandal AK, Meng Z, Rainka MP, Yu T, Shih NY, Siddiqui MA, Liu M, Tevar S, Lee S, Liang L, Gray K, Yaremko B, Jones J, Smith EB, Prelusky DB, Basso AD.

Bioorg Med Chem Lett. 2010 Nov 15;20(22):6739-43. doi: 10.1016/j.bmcl.2010.08.140. Epub 2010 Sep 18.

PMID:
20855207
17.

Treatment options for multiple sclerosis: current and emerging therapies.

Gawronski KM, Rainka MM, Patel MJ, Gengo FM.

Pharmacotherapy. 2010 Sep;30(9):916-27. doi: 10.1592/phco.30.9.916. Review.

PMID:
20795847
18.

Heterobiaryl purine derivatives as potent antiproliferative agents: inhibitors of cyclin dependent kinases. Part II.

Trova MP, Barnes KD, Alicea L, Benanti T, Bielaska M, Bilotta J, Bliss B, Duong TN, Haydar S, Herr RJ, Hui Y, Johnson M, Lehman JM, Peace D, Rainka M, Snider P, Salamone S, Tregay S, Zheng X, Friedrich TD.

Bioorg Med Chem Lett. 2009 Dec 1;19(23):6613-7. doi: 10.1016/j.bmcl.2009.10.011. Epub 2009 Oct 12.

PMID:
19854650
19.

Attenuation of risperidone-induced hyperprolactinemia with the addition of aripiprazole.

Rainka MM, Capote HA, Ross CA, Gengo FM.

J Clin Pharm Ther. 2009 Oct;34(5):595-8. doi: 10.1111/j.1365-2710.2008.01009.x.

PMID:
19744015
20.

Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events.

Gengo FM, Rainka M, Robson M, Gengo MF, Forrest A, Hourihane M, Bates V.

J Clin Pharmacol. 2008 Mar;48(3):335-43. doi: 10.1177/0091270007313324. Epub 2008 Jan 25.

PMID:
18223144
21.

Population pharmacodynamic modelling of aspirin- and Ibuprofen-induced inhibition of platelet aggregation in healthy subjects.

Hong Y, Gengo FM, Rainka MM, Bates VE, Mager DE.

Clin Pharmacokinet. 2008;47(2):129-37.

PMID:
18193919
22.

Effects of ibuprofen on the magnitude and duration of aspirin's inhibition of platelet aggregation: clinical consequences in stroke prophylaxis.

Gengo FM, Rubin L, Robson M, Rainka M, Gengo MF, Mager DE, Bates V.

J Clin Pharmacol. 2008 Jan;48(1):117-22.

PMID:
18094224
23.
24.

Copper-catalyzed asymmetric conjugate reduction as a route to novel beta-azaheterocyclic acid derivatives.

Rainka MP, Aye Y, Buchwald SL.

Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5821-3. Epub 2004 Apr 5.

25.
26.

A highly active Suzuki catalyst for the synthesis of sterically hindered biaryls: novel ligand coordination.

Yin J, Rainka MP, Zhang XX, Buchwald SL.

J Am Chem Soc. 2002 Feb 20;124(7):1162-3.

PMID:
11841272

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