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Items: 8

1.

Allelic expression analysis of the osteoarthritis susceptibility locus that maps to chromosome 3p21 reveals cis-acting eQTLs at GNL3 and SPCS1.

Gee F, Clubbs CF, Raine EV, Reynard LN, Loughlin J.

BMC Med Genet. 2014 May 4;15:53. doi: 10.1186/1471-2350-15-53.

2.

Identification and analysis of a SMAD3 cis-acting eQTL operating in primary osteoarthritis and in the aneurysms and osteoarthritis syndrome.

Raine EV, Reynard LN, van de Laar IM, Bertoli-Avella AM, Loughlin J.

Osteoarthritis Cartilage. 2014 May;22(5):698-705. doi: 10.1016/j.joca.2014.02.931. Epub 2014 Feb 28.

3.

Allelic expression analysis of the osteoarthritis susceptibility gene COL11A1 in human joint tissues.

Raine EV, Dodd AW, Reynard LN, Loughlin J.

BMC Musculoskelet Disord. 2013 Mar 8;14:85. doi: 10.1186/1471-2474-14-85.

4.

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

arcOGEN Consortium; arcOGEN Collaborators, Zeggini E, Panoutsopoulou K, Southam L, Rayner NW, Day-Williams AG, Lopes MC, Boraska V, Esko T, Evangelou E, Hoffman A, Houwing-Duistermaat JJ, Ingvarsson T, Jonsdottir I, Jonnson H, Kerkhof HJ, Kloppenburg M, Bos SD, Mangino M, Metrustry S, Slagboom PE, Thorleifsson G, Raine EV, Ratnayake M, Ricketts M, Beazley C, Blackburn H, Bumpstead S, Elliott KS, Hunt SE, Potter SC, Shin SY, Yadav VK, Zhai G, Sherburn K, Dixon K, Arden E, Aslam N, Battley PK, Carluke I, Doherty S, Gordon A, Joseph J, Keen R, Koller NC, Mitchell S, O'Neill F, Paling E, Reed MR, Rivadeneira F, Swift D, Walker K, Watkins B, Wheeler M, Birrell F, Ioannidis JP, Meulenbelt I, Metspalu A, Rai A, Salter D, Stefansson K, Stykarsdottir U, Uitterlinden AG, van Meurs JB, Chapman K, Deloukas P, Ollier WE, Wallis GA, Arden N, Carr A, Doherty M, McCaskie A, Willkinson JM, Ralston SH, Valdes AM, Spector TD, Loughlin J.

Lancet. 2012 Sep 1;380(9844):815-23. doi: 10.1016/S0140-6736(12)60681-3. Epub 2012 Jul 3.

5.

Gene expression analysis reveals HBP1 as a key target for the osteoarthritis susceptibility locus that maps to chromosome 7q22.

Raine EV, Wreglesworth N, Dodd AW, Reynard LN, Loughlin J.

Ann Rheum Dis. 2012 Dec;71(12):2020-7. doi: 10.1136/annrheumdis-2012-201304. Epub 2012 May 14.

PMID:
22586168
6.

Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues.

Bos SD, Bovée JV, Duijnisveld BJ, Raine EV, van Dalen WJ, Ramos YF, van der Breggen R, Nelissen RG, Slagboom PE, Loughlin J, Meulenbelt I.

Ann Rheum Dis. 2012 Jul;71(7):1254-8. doi: 10.1136/annrheumdis-2011-200981. Epub 2012 Apr 4.

PMID:
22492780
7.

Allelic expression analysis of the osteoarthritis susceptibility locus that maps to MICAL3.

Ratnayake M, Reynard LN, Raine EV, Santibanez-Koref M, Loughlin J.

BMC Med Genet. 2012 Mar 2;13:12. doi: 10.1186/1471-2350-13-12.

8.

Common variations in estrogen-related genes are associated with severe large-joint osteoarthritis: a multicenter genetic and functional study.

Riancho JA, García-Ibarbia C, Gravani A, Raine EV, Rodríguez-Fontenla C, Soto-Hermida A, Rego-Perez I, Dodd AW, Gómez-Reino JJ, Zarrabeitia MT, Garcés CM, Carr A, Blanco F, González A, Loughlin J.

Osteoarthritis Cartilage. 2010 Jul;18(7):927-33. doi: 10.1016/j.joca.2010.04.002. Epub 2010 Apr 22.

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