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Best matches for Rahnenführer J[au]:

Profiling cancer testis antigens in non-small-cell lung cancer. Djureinovic D et al. JCI Insight. (2016)

LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer. Cadenas C et al. Int J Cancer. (2019)

Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes. Grinberg M et al. Arch Toxicol. (2018)

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Items: 1 to 50 of 128

1.

Cost-Constrained feature selection in binary classification: adaptations for greedy forward selection and genetic algorithms.

Jagdhuber R, Lang M, Stenzl A, Neuhaus J, Rahnenführer J.

BMC Bioinformatics. 2020 Jan 28;21(1):26. doi: 10.1186/s12859-020-3361-9.

2.

Determination of benchmark concentrations and their statistical uncertainty for cytotoxicity test data and functional in vitro assays.

Krebs A, Nyffeler J, Karreman C, Schmidt BZ, Kappenberg F, Mellert J, Pallocca G, Pastor M, Rahnenführer J, Leist M.

ALTEX. 2020;37(1):155-163. doi: 10.14573/altex.1912021. Epub 2019 Dec 12.

3.

The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver.

Klindt C, Reich M, Hellwig B, Stindt J, Rahnenführer J, Hengstler JG, Köhrer K, Schoonjans K, Häussinger D, Keitel V.

Cells. 2019 Nov 19;8(11). pii: E1467. doi: 10.3390/cells8111467.

4.

Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances.

Dreser N, Madjar K, Holzer AK, Kapitza M, Scholz C, Kranaster P, Gutbier S, Klima S, Kolb D, Dietz C, Trefzer T, Meisig J, van Thriel C, Henry M, Berthold MR, Blüthgen N, Sachinidis A, Rahnenführer J, Hengstler JG, Waldmann T, Leist M.

Arch Toxicol. 2020 Jan;94(1):151-171. doi: 10.1007/s00204-019-02612-5. Epub 2019 Nov 11.

PMID:
31712839
5.

Model-based optimization of subgroup weights for survival analysis.

Richter J, Madjar K, Rahnenführer J.

Bioinformatics. 2019 Jul 15;35(14):i484-i491. doi: 10.1093/bioinformatics/btz361.

6.

Mechanical strain mimicking breathing amplifies alterations in gene expression induced by SiO2 NPs in lung epithelial cells.

Schmitz C, Welck J, Tavernaro I, Grinberg M, Rahnenführer J, Kiemer AK, van Thriel C, Hengstler JG, Kraegeloh A.

Nanotoxicology. 2019 Nov;13(9):1227-1243. doi: 10.1080/17435390.2019.1650971. Epub 2019 Aug 16.

PMID:
31418614
7.

Corrigendum to Normalization of data for viability and relative cell function curves.

Krebs A, Nyffeler J, Rahnenführer J, Leist M.

ALTEX. 2019;36(3):505. doi: 10.14573/altex.1904113.

8.

Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.

Albrecht W, Kappenberg F, Brecklinghaus T, Stoeber R, Marchan R, Zhang M, Ebbert K, Kirschner H, Grinberg M, Leist M, Moritz W, Cadenas C, Ghallab A, Reinders J, Vartak N, van Thriel C, Golka K, Tolosa L, Castell JV, Damm G, Seehofer D, Lampen A, Braeuning A, Buhrke T, Behr AC, Oberemm A, Gu X, Kittana N, van de Water B, Kreiling R, Fayyaz S, van Aerts L, Smedsrød B, Ellinger-Ziegelbauer H, Steger-Hartmann T, Gundert-Remy U, Zeigerer A, Ullrich A, Runge D, Lee SML, Schiergens TS, Kuepfer L, Aguayo-Orozco A, Sachinidis A, Edlund K, Gardner I, Rahnenführer J, Hengstler JG.

Arch Toxicol. 2019 Jun;93(6):1609-1637. doi: 10.1007/s00204-019-02492-9. Epub 2019 Jun 27.

PMID:
31250071
9.

Statistical analysis of MCC-IMS data for two group comparisons-an exemplary study on two devices.

Horsch S, Baumbach JI, Rahnenführer J.

J Breath Res. 2019 Jun 4;13(3):036011. doi: 10.1088/1752-7163/ab1ee2.

PMID:
31048567
10.

LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer.

Cadenas C, Vosbeck S, Edlund K, Grgas K, Madjar K, Hellwig B, Adawy A, Glotzbach A, Stewart JD, Lesjak MS, Franckenstein D, Claus M, Hayen H, Schriewer A, Gianmoena K, Thaler S, Schmidt M, Micke P, Pontén F, Mardinoglu A, Zhang C, Käfferlein HU, Watzl C, Frank S, Rahnenführer J, Marchan R, Hengstler JG.

Int J Cancer. 2019 Aug 15;145(4):901-915. doi: 10.1002/ijc.32138. Epub 2019 Feb 7.

11.

Prognostic Impact of Tumor Cell Programmed Death Ligand 1 Expression and Immune Cell Infiltration in NSCLC.

Edlund K, Madjar K, Mattsson JSM, Djureinovic D, Lindskog C, Brunnström H, Koyi H, Brandén E, Jirström K, Pontén F, Rahnenführer J, Micke P, Hengstler JG.

J Thorac Oncol. 2019 Apr;14(4):628-640. doi: 10.1016/j.jtho.2018.12.022. Epub 2019 Jan 9.

12.

Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes.

Grinberg M, Stöber RM, Albrecht W, Edlund K, Schug M, Godoy P, Cadenas C, Marchan R, Lampen A, Braeuning A, Buhrke T, Leist M, Oberemm A, Hellwig B, Kamp H, Gardner I, Escher S, Taboureau O, Aguayo-Orozco A, Sachinidis A, Ellinger-Ziegelbauer H, Rahnenführer J, Hengstler JG.

Arch Toxicol. 2018 Dec;92(12):3517-3533. doi: 10.1007/s00204-018-2352-3. Epub 2018 Dec 3. Erratum in: Arch Toxicol. 2019 Jun;93(6):1771.

PMID:
30511339
13.

Relevance of the incubation period in cytotoxicity testing with primary human hepatocytes.

Gu X, Albrecht W, Edlund K, Kappenberg F, Rahnenführer J, Leist M, Moritz W, Godoy P, Cadenas C, Marchan R, Brecklinghaus T, Pardo LT, Castell JV, Gardner I, Han B, Hengstler JG, Stoeber R.

Arch Toxicol. 2018 Dec;92(12):3505-3515. doi: 10.1007/s00204-018-2302-0. Epub 2018 Oct 13.

PMID:
30317417
14.

Normalization of data for viability and relative cell function curves.

Krebs A, Nyffeler J, Rahnenführer J, Leist M.

ALTEX. 2018;35(2):268-271. doi: 10.14573/1803231. Erratum in: ALTEX. 2019;36(3):505.

15.

Assessment of stem cell differentiation based on genome-wide expression profiles.

Godoy P, Schmidt-Heck W, Hellwig B, Nell P, Feuerborn D, Rahnenführer J, Kattler K, Walter J, Blüthgen N, Hengstler JG.

Philos Trans R Soc Lond B Biol Sci. 2018 Jul 5;373(1750). pii: 20170221. doi: 10.1098/rstb.2017.0221. Review.

16.

Impact of intratumoral heterogeneity of breast cancer tissue on quantitative metabolomics using high-resolution magic angle spinning 1 H NMR spectroscopy.

Gogiashvili M, Horsch S, Marchan R, Gianmoena K, Cadenas C, Tanner B, Naumann S, Ersova D, Lippek F, Rahnenführer J, Andersson JT, Hergenröder R, Lambert J, Hengstler JG, Edlund K.

NMR Biomed. 2018 Feb;31(2). doi: 10.1002/nbm.3862. Epub 2017 Dec 5.

PMID:
29206323
17.

Integrative analysis of genome-wide gene copy number changes and gene expression in non-small cell lung cancer.

Jabs V, Edlund K, König H, Grinberg M, Madjar K, Rahnenführer J, Ekman S, Bergkvist M, Holmberg L, Ickstadt K, Botling J, Hengstler JG, Micke P.

PLoS One. 2017 Nov 7;12(11):e0187246. doi: 10.1371/journal.pone.0187246. eCollection 2017.

18.

Comparison and Evaluation of Clustering Algorithms for Tandem Mass Spectra.

Rieder V, Schork KU, Kerschke L, Blank-Landeshammer B, Sickmann A, Rahnenführer J.

J Proteome Res. 2017 Nov 3;16(11):4035-4044. doi: 10.1021/acs.jproteome.7b00427.

PMID:
28959885
19.

A detailed comparison of analysis processes for MCC-IMS data in disease classification-Automated methods can replace manual peak annotations.

Horsch S, Kopczynski D, Kuthe E, Baumbach JI, Rahmann S, Rahnenführer J.

PLoS One. 2017 Sep 14;12(9):e0184321. doi: 10.1371/journal.pone.0184321. eCollection 2017.

20.

A Multicriteria Approach to Find Predictive and Sparse Models with Stable Feature Selection for High-Dimensional Data.

Bommert A, Rahnenführer J, Lang M.

Comput Math Methods Med. 2017;2017:7907163. doi: 10.1155/2017/7907163. Epub 2017 Aug 1.

21.

Variable selection for disease progression models: methods for oncogenetic trees and application to cancer and HIV.

Hainke K, Szugat S, Fried R, Rahnenführer J.

BMC Bioinformatics. 2017 Aug 1;18(1):358. doi: 10.1186/s12859-017-1762-1.

22.

Reef calcifiers are adapted to episodic heat stress but vulnerable to sustained warming.

Stuhr M, Reymond CE, Rieder V, Hallock P, Rahnenführer J, Westphal H, Kucera M.

PLoS One. 2017 Jul 6;12(7):e0179753. doi: 10.1371/journal.pone.0179753. eCollection 2017.

23.

Glycerol-3-phosphate Acyltransferase 1 Promotes Tumor Cell Migration and Poor Survival in Ovarian Carcinoma.

Marchan R, Büttner B, Lambert J, Edlund K, Glaeser I, Blaszkewicz M, Leonhardt G, Marienhoff L, Kaszta D, Anft M, Watzl C, Madjar K, Grinberg M, Rempel E, Hergenröder R, Selinski S, Rahnenführer J, Lesjak MS, Stewart JD, Cadenas C, Hengstler JG.

Cancer Res. 2017 Sep 1;77(17):4589-4601. doi: 10.1158/0008-5472.CAN-16-2065. Epub 2017 Jun 26.

24.

Subtype-specific prognostic impact of different immune signatures in node-negative breast cancer.

Heimes AS, Madjar K, Edlund K, Battista MJ, Almstedt K, Elger T, Krajnak S, Rahnenführer J, Brenner W, Hasenburg A, Hengstler JG, Schmidt M.

Breast Cancer Res Treat. 2017 Sep;165(2):293-300. doi: 10.1007/s10549-017-4327-0. Epub 2017 Jun 5.

PMID:
28585074
25.

Impairment of human neural crest cell migration by prolonged exposure to interferon-beta.

Pallocca G, Nyffeler J, Dolde X, Grinberg M, Gstraunthaler G, Waldmann T, Rahnenführer J, Sachinidis A, Leist M.

Arch Toxicol. 2017 Oct;91(10):3385-3402. doi: 10.1007/s00204-017-1966-1. Epub 2017 Apr 1. Erratum in: Arch Toxicol. 2019 Jun;93(6):1771.

26.

Evaluation of Adjusted and Unadjusted Indirect Comparison Methods in Benefit Assessment. A Simulation Study for Time-to-event Endpoints.

Kühnast S, Schiffner-Rohe J, Rahnenführer J, Leverkus F.

Methods Inf Med. 2017 May 18;56(3):261-267. doi: 10.3414/ME15-02-0016. Epub 2017 Mar 31.

PMID:
28361159
27.

Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters.

Grinberg M, Djureinovic D, Brunnström HR, Mattsson JS, Edlund K, Hengstler JG, La Fleur L, Ekman S, Koyi H, Branden E, Ståhle E, Jirström K, Tracy DK, Pontén F, Botling J, Rahnenführer J, Micke P.

Mod Pathol. 2017 Jul;30(7):964-977. doi: 10.1038/modpathol.2017.14. Epub 2017 Mar 10.

28.

DISMS2: A flexible algorithm for direct proteome- wide distance calculation of LC-MS/MS runs.

Rieder V, Blank-Landeshammer B, Stuhr M, Schell T, Biß K, Kollipara L, Meyer A, Pfenninger M, Westphal H, Sickmann A, Rahnenführer J.

BMC Bioinformatics. 2017 Mar 3;18(1):148. doi: 10.1186/s12859-017-1514-2.

29.

Prognostic significance of interferon regulating factor 4 (IRF4) in node-negative breast cancer.

Heimes AS, Madjar K, Edlund K, Battista MJ, Almstedt K, Gebhard S, Foersch S, Rahnenführer J, Brenner W, Hasenburg A, Hengstler JG, Schmidt M.

J Cancer Res Clin Oncol. 2017 Jul;143(7):1123-1131. doi: 10.1007/s00432-017-2377-7. Epub 2017 Mar 1.

PMID:
28251349
30.

Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells.

Shinde V, Perumal Srinivasan S, Henry M, Rotshteyn T, Hescheler J, Rahnenführer J, Grinberg M, Meisig J, Blüthgen N, Waldmann T, Leist M, Hengstler JG, Sachinidis A.

Stem Cell Res Ther. 2016 Dec 30;7(1):190. doi: 10.1186/s13287-016-0449-2.

31.

Stem Cell Transcriptome Responses and Corresponding Biomarkers That Indicate the Transition from Adaptive Responses to Cytotoxicity.

Waldmann T, Grinberg M, König A, Rempel E, Schildknecht S, Henry M, Holzer AK, Dreser N, Shinde V, Sachinidis A, Rahnenführer J, Hengstler JG, Leist M.

Chem Res Toxicol. 2017 Apr 17;30(4):905-922. doi: 10.1021/acs.chemrestox.6b00259. Epub 2016 Dec 21.

PMID:
28001369
32.

Epsin Family Member 3 and Ribosome-Related Genes Are Associated with Late Metastasis in Estrogen Receptor-Positive Breast Cancer and Long-Term Survival in Non-Small Cell Lung Cancer Using a Genome-Wide Identification and Validation Strategy.

Hellwig B, Madjar K, Edlund K, Marchan R, Cadenas C, Heimes AS, Almstedt K, Lebrecht A, Sicking I, Battista MJ, Micke P, Schmidt M, Hengstler JG, Rahnenführer J.

PLoS One. 2016 Dec 7;11(12):e0167585. doi: 10.1371/journal.pone.0167585. eCollection 2016.

33.

Metabolic profiling of ob/ob mouse fatty liver using HR-MAS 1H-NMR combined with gene expression analysis reveals alterations in betaine metabolism and the transsulfuration pathway.

Gogiashvili M, Edlund K, Gianmoena K, Marchan R, Brik A, Andersson JT, Lambert J, Madjar K, Hellwig B, Rahnenführer J, Hengstler JG, Hergenröder R, Cadenas C.

Anal Bioanal Chem. 2017 Feb;409(6):1591-1606. doi: 10.1007/s00216-016-0100-1. Epub 2016 Nov 28.

PMID:
27896396
34.

Profiling cancer testis antigens in non-small-cell lung cancer.

Djureinovic D, Hallström BM, Horie M, Mattsson JSM, La Fleur L, Fagerberg L, Brunnström H, Lindskog C, Madjar K, Rahnenführer J, Ekman S, Ståhle E, Koyi H, Brandén E, Edlund K, Hengstler JG, Lambe M, Saito A, Botling J, Pontén F, Uhlén M, Micke P.

JCI Insight. 2016 Jul 7;1(10):e86837. doi: 10.1172/jci.insight.86837.

35.

Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests.

Shinde V, Hoelting L, Srinivasan SP, Meisig J, Meganathan K, Jagtap S, Grinberg M, Liebing J, Bluethgen N, Rahnenführer J, Rempel E, Stoeber R, Schildknecht S, Förster S, Godoy P, van Thriel C, Gaspar JA, Hescheler J, Waldmann T, Hengstler JG, Leist M, Sachinidis A.

Arch Toxicol. 2017 Feb;91(2):839-864. doi: 10.1007/s00204-016-1741-8. Epub 2016 May 17.

36.

Maternal eNOS deficiency determines a fatty liver phenotype of the offspring in a sex dependent manner.

Hocher B, Haumann H, Rahnenführer J, Reichetzeder C, Kalk P, Pfab T, Tsuprykov O, Winter S, Hofmann U, Li J, Püschel GP, Lang F, Schuppan D, Schwab M, Schaeffeler E.

Epigenetics. 2016 Jul 2;11(7):539-52. doi: 10.1080/15592294.2016.1184800. Epub 2016 May 13.

37.

Altered Stress-Induced Regulation of Genes in Monocytes in Adults with a History of Childhood Adversity.

Schwaiger M, Grinberg M, Moser D, Zang JC, Heinrichs M, Hengstler JG, Rahnenführer J, Cole S, Kumsta R.

Neuropsychopharmacology. 2016 Sep;41(10):2530-40. doi: 10.1038/npp.2016.57. Epub 2016 Apr 19.

38.

The dipeptidyl peptidase inhibitor linagliptin and the angiotensin II receptor blocker telmisartan show renal benefit by different pathways in rats with 5/6 nephrectomy.

Tsuprykov O, Ando R, Reichetzeder C, von Websky K, Antonenko V, Sharkovska Y, Chaykovska L, Rahnenführer J, Hasan AA, Tammen H, Alter M, Klein T, Ueda S, Yamagishi SI, Okuda S, Hocher B.

Kidney Int. 2016 May;89(5):1049-1061. doi: 10.1016/j.kint.2016.01.016. Epub 2016 Mar 24.

39.

Stem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants.

Hoelting L, Klima S, Karreman C, Grinberg M, Meisig J, Henry M, Rotshteyn T, Rahnenführer J, Blüthgen N, Sachinidis A, Waldmann T, Leist M.

Stem Cells Transl Med. 2016 Apr;5(4):476-87. doi: 10.5966/sctm.2015-0108. Epub 2016 Mar 1.

40.

Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis.

Arbo MD, Melega S, Stöber R, Schug M, Rempel E, Rahnenführer J, Godoy P, Reif R, Cadenas C, de Lourdes Bastos M, Carmo H, Hengstler JG.

Arch Toxicol. 2016 Dec;90(12):3045-3060. Epub 2016 Jan 28.

PMID:
26821219
41.

Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration.

Pallocca G, Grinberg M, Henry M, Frickey T, Hengstler JG, Waldmann T, Sachinidis A, Rahnenführer J, Leist M.

Arch Toxicol. 2016 Jan;90(1):159-80. doi: 10.1007/s00204-015-1658-7. Epub 2015 Dec 26.

42.

Identification of sample annotation errors in gene expression datasets.

Lohr M, Hellwig B, Edlund K, Mattsson JS, Botling J, Schmidt M, Hengstler JG, Micke P, Rahnenführer J.

Arch Toxicol. 2015 Dec;89(12):2265-72. doi: 10.1007/s00204-015-1632-4. Epub 2015 Nov 25.

43.

Gelsolin Is Associated with Longer Metastasis-free Survival and Reduced Cell Migration in Estrogen Receptor-positive Breast Cancer.

Stock AM, Klee F, Edlund K, Grinberg M, Hammad S, Marchan R, Cadenas C, Niggemann B, Zänker KS, Rahnenführer J, Schmidt M, Hengstler JG, Entschladen F.

Anticancer Res. 2015 Oct;35(10):5277-85.

PMID:
26408687
44.

A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors.

Rempel E, Hoelting L, Waldmann T, Balmer NV, Schildknecht S, Grinberg M, Das Gaspar JA, Shinde V, Stöber R, Marchan R, van Thriel C, Liebing J, Meisig J, Blüthgen N, Sachinidis A, Rahnenführer J, Hengstler JG, Leist M.

Arch Toxicol. 2015 Sep;89(9):1599-618. doi: 10.1007/s00204-015-1573-y. Epub 2015 Aug 14.

45.

TiMEx: a waiting time model for mutually exclusive cancer alterations.

Constantinescu S, Szczurek E, Mohammadi P, Rahnenführer J, Beerenwinkel N.

Bioinformatics. 2016 Apr 1;32(7):968-75. doi: 10.1093/bioinformatics/btv400. Epub 2015 Jul 9.

PMID:
26163509
46.

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation.

Shinde V, Klima S, Sureshkumar PS, Meganathan K, Jagtap S, Rempel E, Rahnenführer J, Hengstler JG, Waldmann T, Hescheler J, Leist M, Sachinidis A.

J Vis Exp. 2015 Jun 17;(100):e52333. doi: 10.3791/52333.

47.

From smoking guns to footprints: mining for critical events of toxicity pathways in transcriptome data.

Rahnenführer J, Leist M.

Arch Toxicol. 2015 May;89(5):813-7. doi: 10.1007/s00204-015-1497-6. Epub 2015 Apr 8. No abstract available.

48.

Relaxin-2 does not ameliorate nephropathy in an experimental model of type-1 diabetes.

Dschietzig TB, Krause-Relle K, Hennequin M, von Websky K, Rahnenführer J, Ruppert J, Grön HJ, Armbruster FP, Bathgate RA, Aschenbach JR, Forssmann WG, Hocher B.

Kidney Blood Press Res. 2015;40(1):77-88.

49.

Loss of circadian clock gene expression is associated with tumor progression in breast cancer.

Cadenas C, van de Sandt L, Edlund K, Lohr M, Hellwig B, Marchan R, Schmidt M, Rahnenführer J, Oster H, Hengstler JG.

Cell Cycle. 2014;13(20):3282-91. doi: 10.4161/15384101.2014.954454.

50.

EDI3 links choline metabolism to integrin expression, cell adhesion and spreading.

Lesjak MS, Marchan R, Stewart JD, Rempel E, Rahnenführer J, Hengstler JG.

Cell Adh Migr. 2014;8(5):499-508. doi: 10.4161/cam.29284. Epub 2014 Oct 31.

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