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Items: 1 to 50 of 52

1.

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.

Momozawa Y, Dmitrieva J, Théâtre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori AS, Lecut C, Mariman R, Mni M, Oury C, Altukhov I, Alexeev D, Aulchenko Y, Amininejad L, Bouma G, Hoentjen F, Löwenberg M, Oldenburg B, Pierik MJ, Vander Meulen-de Jong AE, Janneke van der Woude C, Visschedijk MC; International IBD Genetics Consortium, Lathrop M, Hugot JP, Weersma RK, De Vos M, Franchimont D, Vermeire S, Kubo M, Louis E, Georges M.

Nat Commun. 2018 Jun 21;9(1):2427. doi: 10.1038/s41467-018-04365-8.

2.

Streptomyces thermoviolaceus SRC3 strain as a novel source of the antibiotic adjuvant streptazolin: A statistical approach toward the optimized production.

Djinni I, Djoudi W, Souagui S, Rabia F, Rahmouni S, Mancini I, Kecha M.

J Microbiol Methods. 2018 May;148:161-168. doi: 10.1016/j.mimet.2018.04.008. Epub 2018 Apr 14.

PMID:
29665368
3.

Platelets contribute to the initiation of colitis-associated cancer by promoting immunosuppression.

Servais L, Wéra O, Dibato Epoh J, Delierneux C, Bouznad N, Rahmouni S, Mazzucchelli G, Baiwir D, Delvenne P, Lancellotti P, Oury C.

J Thromb Haemost. 2018 Apr;16(4):762-777. doi: 10.1111/jth.13959. Epub 2018 Mar 2.

PMID:
29369476
4.

Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner.

Vandereyken M, Jacques S, Van Overmeire E, Amand M, Rocks N, Delierneux C, Singh P, Singh M, Ghuysen C, Wathieu C, Zurashvili T, Sounni NE, Moutschen M, Gilles C, Oury C, Cataldo D, Van Ginderachter JA, Rahmouni S.

PLoS One. 2017 Oct 11;12(10):e0185786. doi: 10.1371/journal.pone.0185786. eCollection 2017.

5.

Dual-Specificity Phosphatase 3 Deletion Protects Female, but Not Male, Mice from Endotoxemia-Induced and Polymicrobial-Induced Septic Shock.

Vandereyken MM, Singh P, Wathieu CP, Jacques S, Zurashvilli T, Dejager L, Amand M, Musumeci L, Singh M, Moutschen MP, Libert CRF, Rahmouni S.

J Immunol. 2017 Oct 1;199(7):2515-2527. doi: 10.4049/jimmunol.1602092. Epub 2017 Aug 28.

6.

Targeting of C-type lectin-like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides.

Delierneux C, Donis N, Servais L, Wéra O, Lecut C, Vandereyken M, Musumeci L, Rahmouni S, Schneider J, Eble JA, Lancellotti P, Oury C.

J Thromb Haemost. 2017 May;15(5):983-997. doi: 10.1111/jth.13669. Epub 2017 Apr 13.

PMID:
28296036
7.

Functional Analysis of Dual-Specificity Protein Phosphatases in Angiogenesis.

Amand M, Erpicum C, Gilles C, Noël A, Rahmouni S.

Methods Mol Biol. 2016;1447:331-49. doi: 10.1007/978-1-4939-3746-2_18.

PMID:
27514814
8.

Functional Analysis of Protein Tyrosine Phosphatases in Thrombosis and Hemostasis.

Rahmouni S, Hego A, Delierneux C, Wéra O, Musumeci L, Tautz L, Oury C.

Methods Mol Biol. 2016;1447:301-30. doi: 10.1007/978-1-4939-3746-2_17.

PMID:
27514813
9.

The Prosurvival IKK-Related Kinase IKKε Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine.

Göktuna SI, Shostak K, Chau TL, Heukamp LC, Hennuy B, Duong HQ, Ladang A, Close P, Klevernic I, Olivier F, Florin A, Ehx G, Baron F, Vandereyken M, Rahmouni S, Vereecke L, van Loo G, Büttner R, Greten FR, Chariot A.

Cancer Res. 2016 May 1;76(9):2587-99. doi: 10.1158/0008-5472.CAN-15-1473. Epub 2016 Mar 15.

10.

[Antiplatelet drugs: what's new?].

Oury C, Rahmouni S, Lancellotti P.

Med Sci (Paris). 2015 Aug-Sep;31(8-9):720-2. doi: 10.1051/medsci/20153108006. Epub 2015 Sep 4. French. No abstract available.

11.

Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy.

Tautz L, Senis YA, Oury C, Rahmouni S.

Bioorg Med Chem. 2015 Jun 15;23(12):2786-97. doi: 10.1016/j.bmc.2015.03.075. Epub 2015 Apr 4. Review.

12.

DUSP3 Genetic Deletion Confers M2-like Macrophage-Dependent Tolerance to Septic Shock.

Singh P, Dejager L, Amand M, Theatre E, Vandereyken M, Zurashvili T, Singh M, Mack M, Timmermans S, Musumeci L, Dejardin E, Mustelin T, Van Ginderachter JA, Moutschen M, Oury C, Libert C, Rahmouni S.

J Immunol. 2015 May 15;194(10):4951-62. doi: 10.4049/jimmunol.1402431. Epub 2015 Apr 15.

13.

Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis.

Musumeci L, Kuijpers MJ, Gilio K, Hego A, Théâtre E, Maurissen L, Vandereyken M, Diogo CV, Lecut C, Guilmain W, Bobkova EV, Eble JA, Dahl R, Drion P, Rascon J, Mostofi Y, Yuan H, Sergienko E, Chung TD, Thiry M, Senis Y, Moutschen M, Mustelin T, Lancellotti P, Heemskerk JW, Tautz L, Oury C, Rahmouni S.

Circulation. 2015 Feb 17;131(7):656-68. doi: 10.1161/CIRCULATIONAHA.114.010186. Epub 2014 Dec 17.

14.

DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase.

Amand M, Erpicum C, Bajou K, Cerignoli F, Blacher S, Martin M, Dequiedt F, Drion P, Singh P, Zurashvili T, Vandereyken M, Musumeci L, Mustelin T, Moutschen M, Gilles C, Noel A, Rahmouni S.

Mol Cancer. 2014 May 15;13:108. doi: 10.1186/1476-4598-13-108.

15.

Minocycline attenuates HIV-1 infection and suppresses chronic immune activation in humanized NOD/LtsZ-scidIL-2Rγ(null) mice.

Singh M, Singh P, Vaira D, Amand M, Rahmouni S, Moutschen M.

Immunology. 2014 Aug;142(4):562-72. doi: 10.1111/imm.12246.

16.

The RIAD peptidomimetic inhibits HIV-1 replication in humanized NSG mice.

Singh M, Singh P, Vaira D, Torheim EA, Rahmouni S, Taskén K, Moutschen M.

Eur J Clin Invest. 2014 Feb;44(2):146-52. doi: 10.1111/eci.12200. Epub 2013 Nov 28.

PMID:
24283208
17.

Hydrogel micropillars with integrin selective peptidomimetic functionalized nanopatterned tops: a new tool for the measurement of cell traction forces transmitted through αvβ3- or α5β1-integrins.

Rahmouni S, Lindner A, Rechenmacher F, Neubauer S, Sobahi TR, Kessler H, Cavalcanti-Adam EA, Spatz JP.

Adv Mater. 2013 Nov 6;25(41):5869-74. doi: 10.1002/adma.201301338. Epub 2013 Aug 5.

18.

Evaluating effects of tyrosine phosphatase inhibitors on T cell receptor signaling.

Rahmouni S, Delacroix L, Liu WH, Tautz L.

Methods Mol Biol. 2013;1053:241-70. doi: 10.1007/978-1-62703-562-0_15.

PMID:
23860658
19.

Impact of bone marrow-derived mesenchymal stromal cells on experimental xenogeneic graft-versus-host disease.

Bruck F, Belle L, Lechanteur C, de Leval L, Hannon M, Dubois S, Castermans E, Humblet-Baron S, Rahmouni S, Beguin Y, Briquet A, Baron F.

Cytotherapy. 2013 Mar;15(3):267-79. doi: 10.1016/j.jcyt.2012.09.003. Epub 2012 Dec 21.

20.

An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2Rγnull mice allows HIV replication and development of anti-HIV immune responses.

Singh M, Singh P, Gaudray G, Musumeci L, Thielen C, Vaira D, Vandergeeten C, Delacroix L, Van Gulck E, Vanham G, de Leval L, Rahmouni S, Moutschen M.

PLoS One. 2012;7(6):e38491. doi: 10.1371/journal.pone.0038491. Epub 2012 Jun 4.

21.

LYP inhibits T-cell activation when dissociated from CSK.

Vang T, Liu WH, Delacroix L, Wu S, Vasile S, Dahl R, Yang L, Musumeci L, Francis D, Landskron J, Tasken K, Tremblay ML, Lie BA, Page R, Mustelin T, Rahmouni S, Rickert RC, Tautz L.

Nat Chem Biol. 2012 Mar 18;8(5):437-46. doi: 10.1038/nchembio.916.

22.

Increased metabolic rate and insulin sensitivity in male mice lacking the carcino-embryonic antigen-related cell adhesion molecule 2.

Patel PR, Ramakrishnan SK, Kaw MK, Raphael CK, Ghosh S, Marino JS, Heinrich G, Lee SJ, Bourey RE, Hill JW, Jung DY, Morgan DA, Kim JK, Rahmouni K, Najjar SM.

Diabetologia. 2012 Mar;55(3):763-72. doi: 10.1007/s00125-011-2388-x. Epub 2011 Dec 11. Erratum in: Diabetologia. 2012 Mar;55(3):861. Rahmouni, S K [corrected to Rahmouni, K].

23.

Small-Molecule Inhibitors of Vaccinia-H1-Related Phosphatase VHR.

Tautz L, Mustelin T, Wu S, Vossius S, Rahmouni S, Vasile S, Sergienko E, Stonich D, Yuan H, Su Y, Dahl R, Mostofi Y, Chung TDY.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2009 Oct 31 [updated 2010 Oct 4].

24.

Mice with disrupted type I protein kinase A anchoring in T cells resist retrovirus-induced immunodeficiency.

Mosenden R, Singh P, Cornez I, Heglind M, Ruppelt A, Moutschen M, Enerbäck S, Rahmouni S, Taskén K.

J Immunol. 2011 May 1;186(9):5119-30. doi: 10.4049/jimmunol.1100003. Epub 2011 Mar 23.

25.

Thymic self-antigens for the design of a negative/tolerogenic self-vaccination against type 1 diabetes.

Geenen V, Mottet M, Dardenne O, Kermani H, Martens H, Francois JM, Galleni M, Hober D, Rahmouni S, Moutschen M.

Curr Opin Pharmacol. 2010 Aug;10(4):461-72. doi: 10.1016/j.coph.2010.04.005. Epub 2010 Apr 29. Review.

26.

SHIP-1 inhibits CD95/APO-1/Fas-induced apoptosis in primary T lymphocytes and T leukemic cells by promoting CD95 glycosylation independently of its phosphatase activity.

Charlier E, Condé C, Zhang J, Deneubourg L, Di Valentin E, Rahmouni S, Chariot A, Agostinis P, Pang PC, Haslam SM, Dell A, Penninger J, Erneux C, Piette J, Gloire G.

Leukemia. 2010 Apr;24(4):821-32. doi: 10.1038/leu.2010.9. Epub 2010 Feb 11.

27.

Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells.

Wu S, Vossius S, Rahmouni S, Miletic AV, Vang T, Vazquez-Rodriguez J, Cerignoli F, Arimura Y, Williams S, Hayes T, Moutschen M, Vasile S, Pellecchia M, Mustelin T, Tautz L.

J Med Chem. 2009 Nov 12;52(21):6716-23. doi: 10.1021/jm901016k. Erratum in: J Med Chem. 2009 Dec 24;52(24):8058.

28.

Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin.

Creppe C, Malinouskaya L, Volvert ML, Gillard M, Close P, Malaise O, Laguesse S, Cornez I, Rahmouni S, Ormenese S, Belachew S, Malgrange B, Chapelle JP, Siebenlist U, Moonen G, Chariot A, Nguyen L.

Cell. 2009 Feb 6;136(3):551-64. doi: 10.1016/j.cell.2008.11.043. Epub 2009 Jan 29.

29.

In situ assembly of linked geometrically coupled microdevices.

Sawetzki T, Rahmouni S, Bechinger C, Marr DW.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20141-5. doi: 10.1073/pnas.0808808105. Epub 2008 Dec 12.

30.

KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases.

Bayón Y, Trinidad AG, de la Puerta ML, Del Carmen Rodríguez M, Bogetz J, Rojas A, De Pereda JM, Rahmouni S, Williams S, Matsuzawa S, Reed JC, Crespo MS, Mustelin T, Alonso A.

FEBS J. 2008 Aug;275(15):3900-10. doi: 10.1111/j.1742-4658.2008.06537.x. Epub 2008 Jun 28.

31.

Cervix carcinoma is associated with an up-regulation and nuclear localization of the dual-specificity protein phosphatase VHR.

Henkens R, Delvenne P, Arafa M, Moutschen M, Zeddou M, Tautz L, Boniver J, Mustelin T, Rahmouni S.

BMC Cancer. 2008 May 27;8:147. doi: 10.1186/1471-2407-8-147.

32.

[New approaches to the treatment of the HIV-infected patient].

Chandrika K, Dellot P, Frippiat F, Giot JB, Leonard P, Marée R, Mayasi N, Meuris C, Mukeba Tshialala D, Rahmouni S, Uurlings F, Vaira D, Wehenkel L, Demonty J, Moutschen M.

Rev Med Liege. 2007;62 Spec No:47-50. Review. French.

33.

Downregulation of CD94/NKG2A inhibitory receptors on CD8+ T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts.

Zeddou M, Rahmouni S, Vandamme A, Jacobs N, Frippiat F, Leonard P, Schaaf-Lafontaine N, Vaira D, Boniver J, Moutschen M.

Retrovirology. 2007 Oct 10;4:72.

34.

Rottlerin inhibits human T cell responses.

Springael C, Thomas S, Rahmouni S, Vandamme A, Goldman M, Willems F, Vosters O.

Biochem Pharmacol. 2007 Feb 15;73(4):515-25. Epub 2006 Nov 9.

PMID:
17141738
35.

Regulation of MAP kinases by the VHR dual-specific phosphatase: implications for cell growth and differentiation.

Cerignoli F, Rahmouni S, Ronai Z, Mustelin T.

Cell Cycle. 2006 Oct;5(19):2210-5. Epub 2006 Oct 1. Review.

PMID:
17012840
36.

Restoration of SHIP-1 activity in human leukemic cells modifies NF-kappaB activation pathway and cellular survival upon oxidative stress.

Gloire G, Charlier E, Rahmouni S, Volanti C, Chariot A, Erneux C, Piette J.

Oncogene. 2006 Sep 7;25(40):5485-94. Epub 2006 Apr 17.

PMID:
16619039
37.

Loss of the VHR dual-specific phosphatase causes cell-cycle arrest and senescence.

Rahmouni S, Cerignoli F, Alonso A, Tsutji T, Henkens R, Zhu C, Louis-dit-Sully C, Moutschen M, Jiang W, Mustelin T.

Nat Cell Biol. 2006 May;8(5):524-31. Epub 2006 Apr 9. Erratum in: Nat Cell Biol. 2006 Jun;8(6):642.

PMID:
16604064
38.

Lipid raft targeting of hematopoietic protein tyrosine phosphatase by protein kinase C theta-mediated phosphorylation.

Nika K, Charvet C, Williams S, Tautz L, Bruckner S, Rahmouni S, Bottini N, Schoenberger SP, Baier G, Altman A, Mustelin T.

Mol Cell Biol. 2006 Mar;26(5):1806-16.

39.

Prostaglandin E2 induces the expression of functional inhibitory CD94/NKG2A receptors in human CD8+ T lymphocytes by a cAMP-dependent protein kinase A type I pathway.

Zeddou M, Greimers R, de Valensart N, Nayjib B, Tasken K, Boniver J, Moutschen M, Rahmouni S.

Biochem Pharmacol. 2005 Sep 1;70(5):714-24.

PMID:
15978547
40.

Removal of C-terminal SRC kinase from the immune synapse by a new binding protein.

Rahmouni S, Vang T, Alonso A, Williams S, van Stipdonk M, Soncini C, Moutschen M, Schoenberger SP, Mustelin T.

Mol Cell Biol. 2005 Mar;25(6):2227-41.

41.
42.

Cyclo-oxygenase type 2-dependent prostaglandin E2 secretion is involved in retrovirus-induced T-cell dysfunction in mice.

Rahmouni S, Aandahl EM, Nayjib B, Zeddou M, Giannini S, Verlaet M, Greimers R, Boniver J, Tasken K, Moutschen M.

Biochem J. 2004 Dec 15;384(Pt 3):469-76.

43.

Protein tyrosine phosphatases in T cell physiology.

Mustelin T, Alonso A, Bottini N, Huynh H, Rahmouni S, Nika K, Louis-dit-Sully C, Tautz L, Togo SH, Bruckner S, Mena-Duran AV, al-Khouri AM.

Mol Immunol. 2004 Jul;41(6-7):687-700. Review.

PMID:
15220004
44.

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes.

Bottini N, Musumeci L, Alonso A, Rahmouni S, Nika K, Rostamkhani M, MacMurray J, Meloni GF, Lucarelli P, Pellecchia M, Eisenbarth GS, Comings D, Mustelin T.

Nat Genet. 2004 Apr;36(4):337-8. Epub 2004 Mar 7.

PMID:
15004560
45.

[Characterization of a Cl. Perfringens type D strain, isolated in the field and optimization of epsilon toxin biosynthesis in a cell culture].

Maaroufi A, Metoui W, Rahmouni S, Ghram A.

Arch Inst Pasteur Tunis. 2000;77(1-4):67-72. French.

PMID:
14658231
46.

Lck dephosphorylation at Tyr-394 and inhibition of T cell antigen receptor signaling by Yersinia phosphatase YopH.

Alonso A, Bottini N, Bruckner S, Rahmouni S, Williams S, Schoenberger SP, Mustelin T.

J Biol Chem. 2004 Feb 6;279(6):4922-8. Epub 2003 Nov 17.

47.

Role of protein tyrosine phosphatases in T cell activation.

Mustelin T, Rahmouni S, Bottini N, Alonso A.

Immunol Rev. 2003 Feb;191:139-47. Review.

PMID:
12614357
48.

Tyrosine phosphorylation of VHR phosphatase by ZAP-70.

Alonso A, Rahmouni S, Williams S, van Stipdonk M, Jaroszewski L, Godzik A, Abraham RT, Schoenberger SP, Mustelin T.

Nat Immunol. 2003 Jan;4(1):44-8. Epub 2002 Nov 25.

PMID:
12447358
49.

Transient modifications of respiratory capacity in thymic cells during murine radioleukemogenesis.

Verlaet M, Duyckaerts C, Rahmouni S, Denis G, Humblet C, Greimers R, Sluse FE, Boniver J, Defresne MP.

Free Radic Biol Med. 2002 Jul 1;33(1):76-82.

PMID:
12086685
50.

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