Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 295

1.

A computational approach to identify cellular heterogeneity and tissue-specific gene regulatory networks.

Jambusaria A, Klomp J, Hong Z, Rafii S, Dai Y, Malik AB, Rehman J.

BMC Bioinformatics. 2018 Jun 7;19(1):217. doi: 10.1186/s12859-018-2190-6.

2.

Laminar shear stress modulates endothelial luminal surface stiffness in a tissue-specific manner.

Merna N, Wong AK, Barahona V, Llanos P, Kunar B, Palikuqi B, Ginsberg M, Rafii S, Rabbany SY.

Microcirculation. 2018 Jul;25(5):e12455. doi: 10.1111/micc.12455. Epub 2018 May 30.

PMID:
29665185
3.

Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.

Finley LWS, Vardhana SA, Carey BW, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S, Lowe SW, Allis CD, Thompson CB.

Nat Cell Biol. 2018 May;20(5):565-574. doi: 10.1038/s41556-018-0086-3. Epub 2018 Apr 16.

PMID:
29662175
4.

Setting up the dermis for scar-free healing.

Yokoyama M, Rafii S.

Nat Cell Biol. 2018 Apr;20(4):365-366. doi: 10.1038/s41556-018-0080-9. No abstract available.

PMID:
29593323
5.

The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells.

Xu B, Cai L, Butler JM, Chen D, Lu X, Allison DF, Lu R, Rafii S, Parker JS, Zheng D, Wang GG.

Stem Cell Reports. 2018 Mar 13;10(3):675-683. doi: 10.1016/j.stemcr.2018.01.020. Epub 2018 Feb 15.

6.

At the Root: Defining and Halting Progression of Early Chronic Obstructive Pulmonary Disease.

Martinez FJ, Han MK, Allinson JP, Barr RG, Boucher RC, Calverley PMA, Celli BR, Christenson SA, Crystal RG, Fagerås M, Freeman CM, Groenke L, Hoffman EA, Kesimer M, Kostikas K, Paine R 3rd, Rafii S, Rennard SI, Segal LN, Shaykhiev R, Stevenson C, Tal-Singer R, Vestbo J, Woodruff PG, Curtis JL, Wedzicha JA.

Am J Respir Crit Care Med. 2018 Jun 15;197(12):1540-1551. doi: 10.1164/rccm.201710-2028PP. No abstract available.

PMID:
29406779
7.

Histone variant H3.3-mediated chromatin remodeling is essential for paternal genome activation in mouse preimplantation embryos.

Kong Q, Banaszynski LA, Geng F, Zhang X, Zhang J, Zhang H, O'Neill CL, Yan P, Liu Z, Shido K, Palermo GD, Allis CD, Rafii S, Rosenwaks Z, Wen D.

J Biol Chem. 2018 Mar 9;293(10):3829-3838. doi: 10.1074/jbc.RA117.001150. Epub 2018 Jan 22.

PMID:
29358330
8.

Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration.

Wertheimer T, Velardi E, Tsai J, Cooper K, Xiao S, Kloss CC, Ottmüller KJ, Mokhtari Z, Brede C, deRoos P, Kinsella S, Palikuqi B, Ginsberg M, Young LF, Kreines F, Lieberman SR, Lazrak A, Guo P, Malard F, Smith OM, Shono Y, Jenq RR, Hanash AM, Nolan DJ, Butler JM, Beilhack A, Manley NR, Rafii S, Dudakov JA, van den Brink MRM.

Sci Immunol. 2018 Jan 12;3(19). pii: eaal2736. doi: 10.1126/sciimmunol.aal2736.

9.

Platelets prime hematopoietic and vascular niche to drive angiocrine-mediated liver regeneration.

Shido K, Chavez D, Cao Z, Ko J, Rafii S, Ding BS.

Signal Transduct Target Ther. 2017;2. pii: 16044. doi: 10.1038/sigtrans.2016.44. Epub 2017 Feb 17.

10.

Open the gates: vascular neurocrine signaling mobilizes hematopoietic stem and progenitor cells.

Itkin T, Gómez-Salinero JM, Rafii S.

J Clin Invest. 2017 Dec 1;127(12):4231-4234. doi: 10.1172/JCI98323. Epub 2017 Nov 13.

11.

Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression.

Guo P, Poulos MG, Palikuqi B, Badwe CR, Lis R, Kunar B, Ding BS, Rabbany SY, Shido K, Butler JM, Rafii S.

J Clin Invest. 2017 Dec 1;127(12):4242-4256. doi: 10.1172/JCI92309. Epub 2017 Oct 23.

12.

Activated ovarian endothelial cells promote early follicular development and survival.

Kedem A, Aelion-Brauer A, Guo P, Wen D, Ding BS, Lis R, Cheng D, Sandler VM, Rafii S, Rosenwaks Z.

J Ovarian Res. 2017 Sep 19;10(1):64. doi: 10.1186/s13048-017-0354-z.

13.

Leukemic Cells "Gas Up" Leaky Bone Marrow Blood Vessels.

Itkin T, Rafii S.

Cancer Cell. 2017 Sep 11;32(3):276-278. doi: 10.1016/j.ccell.2017.08.012.

PMID:
28898691
14.

Targeting the vascular and perivascular niches as a regenerative therapy for lung and liver fibrosis.

Cao Z, Ye T, Sun Y, Ji G, Shido K, Chen Y, Luo L, Na F, Li X, Huang Z, Ko JL, Mittal V, Qiao L, Chen C, Martinez FJ, Rafii S, Ding BS.

Sci Transl Med. 2017 Aug 30;9(405). pii: eaai8710. doi: 10.1126/scitranslmed.aai8710.

15.

Plasmin regulation of acute cytokine storm.

Gomez-Salinero JM, Rafii S.

Blood. 2017 Jul 6;130(1):5-6. doi: 10.1182/blood-2017-04-776385. No abstract available.

16.

Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors.

Benedicto I, Lehmann GL, Ginsberg M, Nolan DJ, Bareja R, Elemento O, Salfati Z, Alam NM, Prusky GT, Llanos P, Rabbany SY, Maminishkis A, Miller SS, Rafii S, Rodriguez-Boulan E.

Nat Commun. 2017 May 19;8:15374. doi: 10.1038/ncomms15374.

17.

Conversion of adult endothelium to immunocompetent haematopoietic stem cells.

Lis R, Karrasch CC, Poulos MG, Kunar B, Redmond D, Duran JGB, Badwe CR, Schachterle W, Ginsberg M, Xiang J, Tabrizi AR, Shido K, Rosenwaks Z, Elemento O, Speck NA, Butler JM, Scandura JM, Rafii S.

Nature. 2017 May 25;545(7655):439-445. doi: 10.1038/nature22326. Epub 2017 May 17.

18.

Catheter-directed Intraportal Delivery of Endothelial Cell Therapy for Liver Regeneration: A Feasibility Study in a Large-Animal Model of Cirrhosis.

Lee KS, Santagostino SF, Li D, Ramjit A, Serrano K, Ginsberg MD, Ding BS, Rafii S, Madoff DC.

Radiology. 2017 Oct;285(1):114-123. doi: 10.1148/radiol.2017162617. Epub 2017 May 11.

PMID:
28498793
19.

A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells.

Hadland BK, Varnum-Finney B, Mandal PK, Rossi DJ, Poulos MG, Butler JM, Rafii S, Yoder MC, Yoshimoto M, Bernstein ID.

Stem Cell Reports. 2017 Jun 6;8(6):1563-1572. doi: 10.1016/j.stemcr.2017.04.007. Epub 2017 May 4.

20.

ST-Segment Elevation Myocardial Infarction with Acute Stent Thrombosis Presenting as Intractable Hiccups: An Unusual Case.

Zhang F, Tongo ND, Hastings V, Kanzali P, Zhu Z, Chadow H, Rafii SE.

Am J Case Rep. 2017 Apr 29;18:467-471.

21.

Baseline clinical predictors of antitumor response to the PARP inhibitor olaparib in germline BRCA1/2 mutated patients with advanced ovarian cancer.

Rafii S, Gourley C, Kumar R, Geuna E, Ern Ang J, Rye T, Chen LM, Shapira-Frommer R, Friedlander M, Matulonis U, De Greve J, Oza AM, Banerjee S, Molife LR, Gore ME, Kaye SB, Yap TA.

Oncotarget. 2017 Jul 18;8(29):47154-47160. doi: 10.18632/oncotarget.17005.

22.

BGCS uterine cancer guidelines: Recommendations for practice.

Sundar S, Balega J, Crosbie E, Drake A, Edmondson R, Fotopoulou C, Gallos I, Ganesan R, Gupta J, Johnson N, Kitson S, Mackintosh M, Martin-Hirsch P, Miles T, Rafii S, Reed N, Rolland P, Singh K, Sivalingam V, Walther A.

Eur J Obstet Gynecol Reprod Biol. 2017 Jun;213:71-97. doi: 10.1016/j.ejogrb.2017.04.015. Epub 2017 Apr 13. Review.

PMID:
28437632
23.

A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma.

Huang Y, Rajappa P, Hu W, Hoffman C, Cisse B, Kim JH, Gorge E, Yanowitch R, Cope W, Vartanian E, Xu R, Zhang T, Pisapia D, Xiang J, Huse J, Matei I, Peinado H, Bromberg J, Holland E, Ding BS, Rafii S, Lyden D, Greenfield J.

J Clin Invest. 2017 May 1;127(5):1826-1838. doi: 10.1172/JCI86443. Epub 2017 Apr 10.

24.

Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates.

Gori JL, Butler JM, Kunar B, Poulos MG, Ginsberg M, Nolan DJ, Norgaard ZK, Adair JE, Rafii S, Kiem HP.

Stem Cells Transl Med. 2017 Mar;6(3):864-876. doi: 10.5966/sctm.2016-0240. Epub 2016 Oct 14.

25.

Dangerous Liaisons: Deviant Endothelium NOTCHes toward Tumor Metastasis.

Guo P, Rafii S.

Cancer Cell. 2017 Mar 13;31(3):301-303. doi: 10.1016/j.ccell.2017.02.016.

26.

Clinical factors of response in patients with advanced ovarian cancer participating in early phase clinical trials.

George A, Kristeleit R, Rafii S, Michie CO, Bowen R, Michalarea V, van Hagen T, Wong M, Rallis G, Molife LR, Lopez J, Banerji U, Banerjee SN, Gore ME, de Bono JS, Kaye SB, Yap TA.

Eur J Cancer. 2017 May;76:52-59. doi: 10.1016/j.ejca.2017.01.020. Epub 2017 Mar 6.

PMID:
28273485
27.

Phase I, Dose-Escalation, Two-Part Trial of the PARP Inhibitor Talazoparib in Patients with Advanced Germline BRCA1/2 Mutations and Selected Sporadic Cancers.

de Bono J, Ramanathan RK, Mina L, Chugh R, Glaspy J, Rafii S, Kaye S, Sachdev J, Heymach J, Smith DC, Henshaw JW, Herriott A, Patterson M, Curtin NJ, Byers LA, Wainberg ZA.

Cancer Discov. 2017 Jun;7(6):620-629. doi: 10.1158/2159-8290.CD-16-1250. Epub 2017 Feb 27.

28.

Coculturing with endothelial cells promotes in vitro maturation and electrical coupling of human embryonic stem cell-derived cardiomyocytes.

Pasquier J, Gupta R, Rioult D, Hoarau-Véchot J, Courjaret R, Machaca K, Al Suwaidi J, Stanley EG, Rafii S, Elliott DA, Abi Khalil C, Rafii A.

J Heart Lung Transplant. 2017 Jun;36(6):684-693. doi: 10.1016/j.healun.2017.01.001. Epub 2017 Jan 10.

PMID:
28169114
29.

Sox17 drives functional engraftment of endothelium converted from non-vascular cells.

Schachterle W, Badwe CR, Palikuqi B, Kunar B, Ginsberg M, Lis R, Yokoyama M, Elemento O, Scandura JM, Rafii S.

Nat Commun. 2017 Jan 16;8:13963. doi: 10.1038/ncomms13963.

30.

HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver.

Ding BS, Liu CH, Sun Y, Chen Y, Swendeman SL, Jung B, Chavez D, Cao Z, Christoffersen C, Nielsen LB, Schwab SR, Rafii S, Hla T.

JCI Insight. 2016 Dec 22;1(21):e87058. doi: 10.1172/jci.insight.87058.

31.

Adenovirus Protein E4-ORF1 Activation of PI3 Kinase Reveals Differential Regulation of Downstream Effector Pathways in Adipocytes.

Chaudhary N, Gonzalez E, Chang SH, Geng F, Rafii S, Altorki NK, McGraw TE.

Cell Rep. 2016 Dec 20;17(12):3305-3318. doi: 10.1016/j.celrep.2016.11.082.

32.

Endothelial-specific inhibition of NF-κB enhances functional haematopoiesis.

Poulos MG, Ramalingam P, Gutkin MC, Kleppe M, Ginsberg M, Crowley MJ, Elemento O, Levine RL, Rafii S, Kitajewski J, Greenblatt MB, Shim JH, Butler JM.

Nat Commun. 2016 Dec 21;7:13829. doi: 10.1038/ncomms13829.

33.

Molecular Checkpoint Decisions Made by Subverted Vascular Niche Transform Indolent Tumor Cells into Chemoresistant Cancer Stem Cells.

Cao Z, Scandura JM, Inghirami GG, Shido K, Ding BS, Rafii S.

Cancer Cell. 2017 Jan 9;31(1):110-126. doi: 10.1016/j.ccell.2016.11.010. Epub 2016 Dec 15.

34.

An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.

Atapattu L, Saha N, Chheang C, Eissman MF, Xu K, Vail ME, Hii L, Llerena C, Liu Z, Horvay K, Abud HE, Kusebauch U, Moritz RL, Ding BS, Cao Z, Rafii S, Ernst M, Scott AM, Nikolov DB, Lackmann M, Janes PW.

J Exp Med. 2016 Aug 22;213(9):1741-57. doi: 10.1084/jem.20151095. Epub 2016 Aug 8.

35.

Transplantation of Endothelial Cells to Mitigate Acute and Chronic Radiation Injury to Vital Organs.

Rafii S, Ginsberg M, Scandura J, Butler JM, Ding BS.

Radiat Res. 2016 Aug;186(2):196-202. doi: 10.1667/RR14461.1. Epub 2016 Jul 26. Review.

36.

Corrigendum: Distinct bone marrow blood vessels differentially regulate haematopoiesis.

Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG, Kalinkovich A, Ludin A, Golan K, Khatib E, Kumari A, Kollet O, Shakhar G, Butler JM, Rafii S, Adams RH, Scadden DT, Lin CP, Lapidot T.

Nature. 2016 Oct 13;538(7624):274. doi: 10.1038/nature19088. Epub 2016 Jul 20. No abstract available.

PMID:
27437586
37.

Safety and Efficacy of Durvalumab (MEDI4736), an Anti-Programmed Cell Death Ligand-1 Immune Checkpoint Inhibitor, in Patients With Advanced Urothelial Bladder Cancer.

Massard C, Gordon MS, Sharma S, Rafii S, Wainberg ZA, Luke J, Curiel TJ, Colon-Otero G, Hamid O, Sanborn RE, O'Donnell PH, Drakaki A, Tan W, Kurland JF, Rebelatto MC, Jin X, Blake-Haskins JA, Gupta A, Segal NH.

J Clin Oncol. 2016 Sep 10;34(26):3119-25. doi: 10.1200/JCO.2016.67.9761. Epub 2016 Jun 6.

38.

Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells.

Liu Y, Giannopoulou EG, Wen D, Falciatori I, Elemento O, Allis CD, Rafii S, Seandel M.

Nat Commun. 2016 Apr 27;7:11275. doi: 10.1038/ncomms11275.

39.

VEGF-B Improves Metabolic Health through Vascular Pruning of Fat.

Rafii S, Carmeliet P.

Cell Metab. 2016 Apr 12;23(4):571-3. doi: 10.1016/j.cmet.2016.03.012.

40.

Distinct bone marrow blood vessels differentially regulate haematopoiesis.

Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG, Kalinkovich A, Ludin A, Kollet O, Shakhar G, Butler JM, Rafii S, Adams RH, Scadden DT, Lin CP, Lapidot T.

Nature. 2016 Apr 21;532(7599):323-8. doi: 10.1038/nature17624. Epub 2016 Apr 13.

PMID:
27074509
41.

Angiocrine functions of organ-specific endothelial cells.

Rafii S, Butler JM, Ding BS.

Nature. 2016 Jan 21;529(7586):316-25. doi: 10.1038/nature17040. Review.

42.

Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis.

Cao Z, Lis R, Ginsberg M, Chavez D, Shido K, Rabbany SY, Fong GH, Sakmar TP, Rafii S, Ding BS.

Nat Med. 2016 Feb;22(2):154-62. doi: 10.1038/nm.4035. Epub 2016 Jan 18.

43.

VEGF-A/VEGFR Inhibition Restores Hematopoietic Homeostasis in the Bone Marrow and Attenuates Tumor Growth.

O'Donnell RK, Falcon B, Hanson J, Goldstein WE, Perruzzi C, Rafii S, Aird WC, Benjamin LE.

Cancer Res. 2016 Feb 1;76(3):517-24. doi: 10.1158/0008-5472.CAN-14-3023. Epub 2015 Dec 30.

44.

VE-cadherin cleavage by ovarian cancer microparticles induces β-catenin phosphorylation in endothelial cells.

Al Thawadi H, Abu-Kaoud N, Al Farsi H, Hoarau-Véchot J, Rafii S, Rafii A, Pasquier J.

Oncotarget. 2016 Feb 2;7(5):5289-305. doi: 10.18632/oncotarget.6677.

45.

Complications of hyperglycaemia with PI3K-AKT-mTOR inhibitors in patients with advanced solid tumours on Phase I clinical trials.

Geuna E, Roda D, Rafii S, Jimenez B, Capelan M, Rihawi K, Montemurro F, Yap TA, Kaye SB, De Bono JS, Molife LR, Banerji U.

Br J Cancer. 2015 Dec 1;113(11):1541-7. doi: 10.1038/bjc.2015.373. Epub 2015 Nov 10.

46.

Direct conversion of human amniotic cells into endothelial cells without transitioning through a pluripotent state.

Ginsberg M, Schachterle W, Shido K, Rafii S.

Nat Protoc. 2015 Dec;10(12):1975-85. doi: 10.1038/nprot.2015.126. Epub 2015 Nov 5.

47.

Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.

Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, Rafii S, Birtwistle MR, Akbarian S, Buchholz BA, Blitzer RD, Nestler EJ, Yuan ZF, Garcia BA, Shen L, Molina H, Allis CD.

Neuron. 2015 Jul 1;87(1):77-94. doi: 10.1016/j.neuron.2015.06.014.

48.

Endothelial MMP14 is required for endothelial-dependent growth support of human airway basal cells.

Ding BS, Gomi K, Rafii S, Crystal RG, Walters MS.

J Cell Sci. 2015 Aug 15;128(16):2983-8. doi: 10.1242/jcs.168179. Epub 2015 Jun 26.

49.

Identification of Reprogrammed Myeloid Cell Transcriptomes in NSCLC.

Durrans A, Gao D, Gupta R, Fischer KR, Choi H, El Rayes T, Ryu S, Nasar A, Spinelli CF, Andrews W, Elemento O, Nolan D, Stiles B, Rafii S, Narula N, Davuluri R, Altorki NK, Mittal V.

PLoS One. 2015 Jun 5;10(6):e0129123. doi: 10.1371/journal.pone.0129123. eCollection 2015.

50.

Slitrk5 Mediates BDNF-Dependent TrkB Receptor Trafficking and Signaling.

Song M, Giza J, Proenca CC, Jing D, Elliott M, Dincheva I, Shmelkov SV, Kim J, Schreiner R, Huang SH, Castrén E, Prekeris R, Hempstead BL, Chao MV, Dictenberg JB, Rafii S, Chen ZY, Rodriguez-Boulan E, Lee FS.

Dev Cell. 2015 Jun 22;33(6):690-702. doi: 10.1016/j.devcel.2015.04.009. Epub 2015 May 21.

Supplemental Content

Support Center