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Items: 1 to 50 of 88

1.

The role of the P2X7 receptor in myeloid-derived suppressor cells and immunosuppression.

Principi E, Raffaghello L.

Curr Opin Pharmacol. 2019 Apr 5;47:82-89. doi: 10.1016/j.coph.2019.02.010. [Epub ahead of print] Review.

PMID:
30959357
2.

The Danger Signal Extracellular ATP Is Involved in the Immunomediated Damage of α-Sarcoglycan-Deficient Muscular Dystrophy.

Gazzerro E, Baratto S, Assereto S, Baldassari S, Panicucci C, Raffaghello L, Scudieri P, De Battista D, Fiorillo C, Volpi S, Chaabane L, Malnati M, Messina G, Bruzzone S, Traggiai E, Grassi F, Minetti C, Bruno C.

Am J Pathol. 2019 Feb;189(2):354-369. doi: 10.1016/j.ajpath.2018.10.008. Epub 2018 Nov 16.

PMID:
30448410
3.

Effect of starvation on brain glucose metabolism and 18F-2-fluoro-2-deoxyglucose uptake: an experimental in-vivo and ex-vivo study.

Buschiazzo A, Cossu V, Bauckneht M, Orengo A, Piccioli P, Emionite L, Bianchi G, Grillo F, Rocchi A, Di Giulio F, Fiz F, Raffaghello L, Nobili F, Bruno S, Caviglia G, Ravera S, Benfenati F, Piana M, Morbelli S, Sambuceti G, Marini C.

EJNMMI Res. 2018 Jun 11;8(1):44. doi: 10.1186/s13550-018-0398-0.

4.

Curcumin induces a fatal energetic impairment in tumor cells in vitro and in vivo by inhibiting ATP-synthase activity.

Bianchi G, Ravera S, Traverso C, Amaro A, Piaggio F, Emionite L, Bachetti T, Pfeffer U, Raffaghello L.

Carcinogenesis. 2018 Sep 21;39(9):1141-1150. doi: 10.1093/carcin/bgy076.

PMID:
29860383
5.

Bevacizumab-mediated tumor vasculature remodelling improves tumor infiltration and antitumor efficacy of GD2-CAR T cells in a human neuroblastoma preclinical model.

Bocca P, Di Carlo E, Caruana I, Emionite L, Cilli M, De Angelis B, Quintarelli C, Pezzolo A, Raffaghello L, Morandi F, Locatelli F, Pistoia V, Prigione I.

Oncoimmunology. 2017 Oct 4;7(1):e1378843. doi: 10.1080/2162402X.2017.1378843. eCollection 2017.

6.

Targeting of PHOX2B expression allows the identification of drugs effective in counteracting neuroblastoma cell growth.

Di Zanni E, Bianchi G, Ravazzolo R, Raffaghello L, Ceccherini I, Bachetti T.

Oncotarget. 2017 Aug 4;8(42):72133-72146. doi: 10.18632/oncotarget.19922. eCollection 2017 Sep 22.

7.

Use of luciferase probes to measure ATP in living cells and animals.

Morciano G, Sarti AC, Marchi S, Missiroli S, Falzoni S, Raffaghello L, Pistoia V, Giorgi C, Di Virgilio F, Pinton P.

Nat Protoc. 2017 Aug;12(8):1542-1562. doi: 10.1038/nprot.2017.052. Epub 2017 Jul 6.

PMID:
28683062
8.

Metabolic Alterations at the Crossroad of Aging and Oncogenesis.

Raffaghello L, Longo V.

Int Rev Cell Mol Biol. 2017;332:1-42. doi: 10.1016/bs.ircmb.2017.01.003. Epub 2017 Feb 28. Review.

PMID:
28526131
9.

Mesenchymal stromal cells and autoimmunity.

Pistoia V, Raffaghello L.

Int Immunol. 2017 Feb 1;29(2):49-58. doi: 10.1093/intimm/dxx008. Review.

PMID:
28338763
10.

Discovery of a novel glucose metabolism in cancer: The role of endoplasmic reticulum beyond glycolysis and pentose phosphate shunt.

Marini C, Ravera S, Buschiazzo A, Bianchi G, Orengo AM, Bruno S, Bottoni G, Emionite L, Pastorino F, Monteverde E, Garaboldi L, Martella R, Salani B, Maggi D, Ponzoni M, Fais F, Raffaghello L, Sambuceti G.

Sci Rep. 2016 Apr 28;6:25092. doi: 10.1038/srep25092.

11.

Pancreatic metastasis from mycosis fungoides mimicking primary pancreatic tumor.

Ceriolo P, Fausti V, Cinotti E, Bonadio S, Raffaghello L, Bianchi G, Orcioni GF, Fiocca R, Rongioletti F, Pistoia V, Borgonovo G.

World J Gastroenterol. 2016 Mar 28;22(12):3496-501. doi: 10.3748/wjg.v22.i12.3496.

12.

Divergent targets of glycolysis and oxidative phosphorylation result in additive effects of metformin and starvation in colon and breast cancer.

Marini C, Bianchi G, Buschiazzo A, Ravera S, Martella R, Bottoni G, Petretto A, Emionite L, Monteverde E, Capitanio S, Inglese E, Fabbi M, Bongioanni F, Garaboldi L, Bruzzi P, Orengo AM, Raffaghello L, Sambuceti G.

Sci Rep. 2016 Jan 22;6:19569. doi: 10.1038/srep19569.

13.

Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model.

Sociali G, Raffaghello L, Magnone M, Zamporlini F, Emionite L, Sturla L, Bianchi G, Vigliarolo T, Nahimana A, Nencioni A, Raffaelli N, Bruzzone S.

Oncotarget. 2016 Jan 19;7(3):2968-84. doi: 10.18632/oncotarget.6502.

14.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M.

Semin Cancer Biol. 2015 Dec;35 Suppl:S276-S304. doi: 10.1016/j.semcancer.2015.09.007. Review.

15.

Dysregulated metabolism contributes to oncogenesis.

Hirschey MD, DeBerardinis RJ, Diehl AME, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, Michelotti G, Muralidhar V, Murphy MP, Pedersen PL, Poore B, Raffaghello L, Rathmell JC, Sivanand S, Vander Heiden MG, Wellen KE; Target Validation Team.

Semin Cancer Biol. 2015 Dec;35 Suppl:S129-S150. doi: 10.1016/j.semcancer.2015.10.002. Epub 2015 Oct 8. Review.

16.

Classification and biology of tumour associated stromal cells.

Raffaghello L, Dazzi F.

Immunol Lett. 2015 Dec;168(2):175-82. doi: 10.1016/j.imlet.2015.06.016. Epub 2015 Jul 2. Review.

PMID:
26145459
17.

Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models.

Bianchi G, Martella R, Ravera S, Marini C, Capitanio S, Orengo A, Emionite L, Lavarello C, Amaro A, Petretto A, Pfeffer U, Sambuceti G, Pistoia V, Raffaghello L, Longo VD.

Oncotarget. 2015 May 20;6(14):11806-19.

18.

The P2X7 receptor is a key modulator of the PI3K/GSK3β/VEGF signaling network: evidence in experimental neuroblastoma.

Amoroso F, Capece M, Rotondo A, Cangelosi D, Ferracin M, Franceschini A, Raffaghello L, Pistoia V, Varesio L, Adinolfi E.

Oncogene. 2015 Oct 8;34(41):5240-51. doi: 10.1038/onc.2014.444. Epub 2015 Jan 26.

PMID:
25619831
19.

Accelerated tumor progression in mice lacking the ATP receptor P2X7.

Adinolfi E, Capece M, Franceschini A, Falzoni S, Giuliani AL, Rotondo A, Sarti AC, Bonora M, Syberg S, Corigliano D, Pinton P, Jorgensen NR, Abelli L, Emionite L, Raffaghello L, Pistoia V, Di Virgilio F.

Cancer Res. 2015 Feb 15;75(4):635-44. doi: 10.1158/0008-5472.CAN-14-1259. Epub 2014 Dec 26.

20.

Cancer associated fibroblasts in hematological malignancies.

Raffaghello L, Vacca A, Pistoia V, Ribatti D.

Oncotarget. 2015 Feb 20;6(5):2589-603. Review.

21.

Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia.

Pezzolo A, Marimpietri D, Raffaghello L, Cocco C, Pistorio A, Gambini C, Cilli M, Horenstein A, Malavasi F, Pistoia V.

Oncotarget. 2014 Nov 15;5(21):10368-81.

22.

ATP/P2X7 axis modulates myeloid-derived suppressor cell functions in neuroblastoma microenvironment.

Bianchi G, Vuerich M, Pellegatti P, Marimpietri D, Emionite L, Marigo I, Bronte V, Di Virgilio F, Pistoia V, Raffaghello L.

Cell Death Dis. 2014 Mar 20;5:e1135. doi: 10.1038/cddis.2014.109.

23.

Unveiling the role of TNF-α in mesenchymal stromal cell-mediated immunosuppression.

Pistoia V, Raffaghello L.

Eur J Immunol. 2014 Feb;44(2):352-6. doi: 10.1002/eji.201344372.

24.

Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression.

Marimpietri D, Petretto A, Raffaghello L, Pezzolo A, Gagliani C, Tacchetti C, Mauri P, Melioli G, Pistoia V.

PLoS One. 2013 Sep 19;8(9):e75054. doi: 10.1371/journal.pone.0075054. eCollection 2013.

25.

CCL5-glutamate interaction in central nervous system: Early and acute presynaptic defects in EAE mice.

Di Prisco S, Merega E, Milanese M, Summa M, Casazza S, Raffaghello L, Pistoia V, Uccelli A, Pittaluga A.

Neuropharmacology. 2013 Dec;75:337-46. doi: 10.1016/j.neuropharm.2013.07.037. Epub 2013 Aug 16.

PMID:
23958452
26.

Immunosuppressive microenvironment in neuroblastoma.

Pistoia V, Morandi F, Bianchi G, Pezzolo A, Prigione I, Raffaghello L.

Front Oncol. 2013 Jun 26;3:167. doi: 10.3389/fonc.2013.00167. eCollection 2013.

27.

Role of BAFF in Opsoclonus-Myoclonus syndrome, a bridge between cancer and autoimmunity.

Raffaghello L, Fuhlhuber V, Bianchi G, Conte M, Blaes F, Gambini C, Pistoia V.

J Leukoc Biol. 2013 Jul;94(1):183-91. doi: 10.1189/jlb.0213106. Epub 2013 Apr 22.

PMID:
23610147
28.

Mechanisms of the antitumor activity of human Vγ9Vδ2 T cells in combination with zoledronic acid in a preclinical model of neuroblastoma.

Di Carlo E, Bocca P, Emionite L, Cilli M, Cipollone G, Morandi F, Raffaghello L, Pistoia V, Prigione I.

Mol Ther. 2013 May;21(5):1034-43. doi: 10.1038/mt.2013.38. Epub 2013 Mar 12.

29.

MYCN: from oncoprotein to tumor-associated antigen.

Pistoia V, Morandi F, Pezzolo A, Raffaghello L, Prigione I.

Front Oncol. 2012 Nov 16;2:174. doi: 10.3389/fonc.2012.00174. eCollection 2012.

30.

Close interactions between mesenchymal stem cells and neuroblastoma cell lines lead to tumor growth inhibition.

Bianchi G, Morandi F, Cilli M, Daga A, Bocelli-Tyndall C, Gambini C, Pistoia V, Raffaghello L.

PLoS One. 2012;7(10):e48654. doi: 10.1371/journal.pone.0048654. Epub 2012 Oct 31.

31.

Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents.

Milelli A, Tumiatti V, Micco M, Rosini M, Zuccari G, Raffaghello L, Bianchi G, Pistoia V, Fernando Díaz J, Pera B, Trigili C, Barasoain I, Musetti C, Toniolo M, Sissi C, Alcaro S, Moraca F, Zini M, Stefanelli C, Minarini A.

Eur J Med Chem. 2012 Nov;57:417-28. doi: 10.1016/j.ejmech.2012.06.045. Epub 2012 Jul 4.

PMID:
22819507
32.

Expression of P2X7 receptor increases in vivo tumor growth.

Adinolfi E, Raffaghello L, Giuliani AL, Cavazzini L, Capece M, Chiozzi P, Bianchi G, Kroemer G, Pistoia V, Di Virgilio F.

Cancer Res. 2012 Jun 15;72(12):2957-69. doi: 10.1158/0008-5472.CAN-11-1947. Epub 2012 Apr 13.

33.

Starvation, detoxification, and multidrug resistance in cancer therapy.

Lee C, Raffaghello L, Longo VD.

Drug Resist Updat. 2012 Feb-Apr;15(1-2):114-22. doi: 10.1016/j.drup.2012.01.004. Epub 2012 Mar 4. Review.

34.

Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy.

Lee C, Raffaghello L, Brandhorst S, Safdie FM, Bianchi G, Martin-Montalvo A, Pistoia V, Wei M, Hwang S, Merlino A, Emionite L, de Cabo R, Longo VD.

Sci Transl Med. 2012 Mar 7;4(124):124ra27. doi: 10.1126/scitranslmed.3003293. Epub 2012 Feb 8.

35.

Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells.

Cea M, Soncini D, Fruscione F, Raffaghello L, Garuti A, Emionite L, Moran E, Magnone M, Zoppoli G, Reverberi D, Caffa I, Salis A, Cagnetta A, Bergamaschi M, Casciaro S, Pierri I, Damonte G, Ansaldi F, Gobbi M, Pistoia V, Ballestrero A, Patrone F, Bruzzone S, Nencioni A.

PLoS One. 2011;6(7):e22739. doi: 10.1371/journal.pone.0022739. Epub 2011 Jul 27.

36.

Cytokines in neuroblastoma: from pathogenesis to treatment.

Pistoia V, Bianchi G, Borgonovo G, Raffaghello L.

Immunotherapy. 2011 Jul;3(7):895-907. doi: 10.2217/imt.11.80. Review.

PMID:
21751957
37.

Damage-associated molecular patterns (DAMPs) and mesenchymal stem cells: a matter of attraction and excitement.

Pistoia V, Raffaghello L.

Eur J Immunol. 2011 Jul;41(7):1828-31. doi: 10.1002/eji.201141724.

38.

Serum levels of cytoplasmic melanoma-associated antigen at diagnosis may predict clinical relapse in neuroblastoma patients.

Morandi F, Corrias MV, Levreri I, Scaruffi P, Raffaghello L, Carlini B, Bocca P, Prigione I, Stigliani S, Amoroso L, Ferrone S, Pistoia V.

Cancer Immunol Immunother. 2011 Oct;60(10):1485-95. doi: 10.1007/s00262-011-1052-0. Epub 2011 Jun 10.

39.

Immunosuppressive cells and tumour microenvironment: focus on mesenchymal stem cells and myeloid derived suppressor cells.

Bianchi G, Borgonovo G, Pistoia V, Raffaghello L.

Histol Histopathol. 2011 Jul;26(7):941-51. doi: 10.14670/HH-26.941. Review.

PMID:
21630223
40.

Immunosuppressive treatments in acute myocardial infarction and stroke.

Raffaghello L, Bianchi G, Pistoia V.

Curr Pharm Biotechnol. 2012 Jan;13(1):59-67. Review.

PMID:
21470161
41.

Oct-4+/Tenascin C+ neuroblastoma cells serve as progenitors of tumor-derived endothelial cells.

Pezzolo A, Parodi F, Marimpietri D, Raffaghello L, Cocco C, Pistorio A, Mosconi M, Gambini C, Cilli M, Deaglio S, Malavasi F, Pistoia V.

Cell Res. 2011 Oct;21(10):1470-86. doi: 10.1038/cr.2011.38. Epub 2011 Mar 15.

42.

Disclosing the mysteries of the central nervous system sanctuary for acute lymphoblastic leukemia cells.

Pistoia V, Raffaghello L.

Leuk Res. 2011 Jun;35(6):699-700. doi: 10.1016/j.leukres.2011.01.031. Epub 2011 Feb 16. No abstract available.

PMID:
21329976
43.

Fasting and differential chemotherapy protection in patients.

Raffaghello L, Safdie F, Bianchi G, Dorff T, Fontana L, Longo VD.

Cell Cycle. 2010 Nov 15;9(22):4474-6. Epub 2010 Nov 15.

44.

A novel mechanism of soluble HLA-G mediated immune modulation: downregulation of T cell chemokine receptor expression and impairment of chemotaxis.

Morandi F, Ferretti E, Bocca P, Prigione I, Raffaghello L, Pistoia V.

PLoS One. 2010 Jul 23;5(7):e11763. doi: 10.1371/journal.pone.0011763.

45.

Systemic and intraplaque mediators of inflammation are increased in patients symptomatic for ischemic stroke.

Montecucco F, Lenglet S, Gayet-Ageron A, Bertolotto M, Pelli G, Palombo D, Pane B, Spinella G, Steffens S, Raffaghello L, Pistoia V, Ottonello L, Pende A, Dallegri F, Mach F.

Stroke. 2010 Jul;41(7):1394-404. doi: 10.1161/STROKEAHA.110.578369. Epub 2010 Jun 10.

PMID:
20538699
46.

Potential of mesenchymal stem cells for the therapy of autoimmune diseases.

Pistoia V, Raffaghello L.

Expert Rev Clin Immunol. 2010 Mar;6(2):211-8. Review.

PMID:
20402384
47.

Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index.

Lee C, Safdie FM, Raffaghello L, Wei M, Madia F, Parrella E, Hwang D, Cohen P, Bianchi G, Longo VD.

Cancer Res. 2010 Feb 15;70(4):1564-72. doi: 10.1158/0008-5472.CAN-09-3228. Epub 2010 Feb 9.

48.

Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repression.

Nencioni A, Cea M, Garuti A, Passalacqua M, Raffaghello L, Soncini D, Moran E, Zoppoli G, Pistoia V, Patrone F, Ballestrero A.

PLoS One. 2010 Feb 2;5(2):e9024. doi: 10.1371/journal.pone.0009024.

49.

CX3CR1 is expressed by human B lymphocytes and mediates [corrected] CX3CL1 driven chemotaxis of tonsil centrocytes.

Corcione A, Ferretti E, Bertolotto M, Fais F, Raffaghello L, Gregorio A, Tenca C, Ottonello L, Gambini C, Furtado G, Lira S, Pistoia V.

PLoS One. 2009 Dec 29;4(12):e8485. doi: 10.1371/journal.pone.0008485. Erratum in: PLoS One. 2010;5(1). doi: 10.1371/annotation/50da3cf8-38cb-4985-8875-e41aa03191ba.

50.

Editorial: in-and-out blood vessels: new insights into T cell reverse transmigration.

Raffaghello L, Pistoia V.

J Leukoc Biol. 2009 Dec;86(6):1271-3. doi: 10.1189/jlb.0409283. No abstract available.

PMID:
19948520

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