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Items: 15


β-arrestins: regulatory role and therapeutic potential in opioid and cannabinoid receptor-mediated analgesia.

Raehal KM, Bohn LM.

Handb Exp Pharmacol. 2014;219:427-43. doi: 10.1007/978-3-642-41199-1_22. Review.


GIRK channel modulation by assembly with allosterically regulated RGS proteins.

Zhou H, Chisari M, Raehal KM, Kaltenbronn KM, Bohn LM, Mennerick SJ, Blumer KJ.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):19977-82. doi: 10.1073/pnas.1214337109. Epub 2012 Nov 19.


β-arrestin2 regulates cannabinoid CB1 receptor signaling and adaptation in a central nervous system region-dependent manner.

Nguyen PT, Schmid CL, Raehal KM, Selley DE, Bohn LM, Sim-Selley LJ.

Biol Psychiatry. 2012 Apr 15;71(8):714-24. doi: 10.1016/j.biopsych.2011.11.027. Epub 2012 Jan 20.


Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.

Raehal KM, Schmid CL, Groer CE, Bohn LM.

Pharmacol Rev. 2011 Dec;63(4):1001-19. doi: 10.1124/pr.111.004598. Epub 2011 Aug 26. Review.


Synthesis of conolidine, a potent non-opioid analgesic for tonic and persistent pain.

Tarselli MA, Raehal KM, Brasher AK, Streicher JM, Groer CE, Cameron MD, Bohn LM, Micalizio GC.

Nat Chem. 2011 Jun;3(6):449-53. doi: 10.1038/nchem.1050.


The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.

Raehal KM, Bohn LM.

Neuropharmacology. 2011 Jan;60(1):58-65. doi: 10.1016/j.neuropharm.2010.08.003. Epub 2010 Aug 14.


Morphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6.

Raehal KM, Schmid CL, Medvedev IO, Gainetdinov RR, Premont RT, Bohn LM.

Drug Alcohol Depend. 2009 Oct 1;104(3):187-96. doi: 10.1016/j.drugalcdep.2009.04.011. Epub 2009 Jun 3.


Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies.

Gupta A, Rozenfeld R, Gomes I, Raehal KM, Décaillot FM, Bohn LM, Devi LA.

J Biol Chem. 2008 Apr 18;283(16):10735-44. doi: 10.1074/jbc.M709454200. Epub 2008 Feb 6.


Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo.

Schmid CL, Raehal KM, Bohn LM.

Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):1079-84. doi: 10.1073/pnas.0708862105. Epub 2008 Jan 14.


Opioid receptor signaling: relevance for gastrointestinal therapy.

Bohn LM, Raehal KM.

Curr Opin Pharmacol. 2006 Dec;6(6):559-63. Epub 2006 Aug 28. Review.


Mu opioid receptor regulation and opiate responsiveness.

Raehal KM, Bohn LM.

AAPS J. 2005 Oct 19;7(3):E587-91. Review.


Morphine side effects in beta-arrestin 2 knockout mice.

Raehal KM, Walker JK, Bohn LM.

J Pharmacol Exp Ther. 2005 Sep;314(3):1195-201. Epub 2005 May 25.


In vivo characterization of 6beta-naltrexol, an opioid ligand with less inverse agonist activity compared with naltrexone and naloxone in opioid-dependent mice.

Raehal KM, Lowery JJ, Bhamidipati CM, Paolino RM, Blair JR, Wang D, Sadée W, Bilsky EJ.

J Pharmacol Exp Ther. 2005 Jun;313(3):1150-62. Epub 2005 Feb 16.


Basal signaling activity of mu opioid receptor in mouse brain: role in narcotic dependence.

Wang D, Raehal KM, Lin ET, Lowery JJ, Kieffer BL, Bilsky EJ, Sadée W.

J Pharmacol Exp Ther. 2004 Feb;308(2):512-20. Epub 2003 Nov 4.


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