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Items: 10

1.

Mechanisms of osteoclastogenesis inhibition by a novel class of biphenyl-type cannabinoid CB(2) receptor inverse agonists.

Schuehly W, Paredes JM, Kleyer J, Huefner A, Anavi-Goffer S, Raduner S, Altmann KH, Gertsch J.

Chem Biol. 2011 Aug 26;18(8):1053-64. doi: 10.1016/j.chembiol.2011.05.012.

2.

Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin.

Leonti M, Casu L, Raduner S, Cottiglia F, Floris C, Altmann KH, Gertsch J.

Biochem Pharmacol. 2010 Jun 15;79(12):1815-26. doi: 10.1016/j.bcp.2010.02.015. Epub 2010 Mar 3.

PMID:
20206138
3.

Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts.

Chicca A, Raduner S, Pellati F, Strompen T, Altmann KH, Schoop R, Gertsch J.

Int Immunopharmacol. 2009 Jul;9(7-8):850-8. doi: 10.1016/j.intimp.2009.03.006. Epub 2009 Mar 19.

PMID:
19303464
4.

Discovery of novel CB2 receptor ligands by a pharmacophore-based virtual screening workflow.

Markt P, Feldmann C, Rollinger JM, Raduner S, Schuster D, Kirchmair J, Distinto S, Spitzer GM, Wolber G, Laggner C, Altmann KH, Langer T, Gertsch J.

J Med Chem. 2009 Jan 22;52(2):369-78. doi: 10.1021/jm801044g.

PMID:
19143566
5.

In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolens.

Rollinger JM, Schuster D, Danzl B, Schwaiger S, Markt P, Schmidtke M, Gertsch J, Raduner S, Wolber G, Langer T, Stuppner H.

Planta Med. 2009 Feb;75(3):195-204. doi: 10.1055/s-0028-1088397. Epub 2008 Dec 18. Erratum in: Planta Med. 2009 Feb;75(3):293.

6.

Beta-caryophyllene is a dietary cannabinoid.

Gertsch J, Leonti M, Raduner S, Racz I, Chen JZ, Xie XQ, Altmann KH, Karsak M, Zimmer A.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9099-104. doi: 10.1073/pnas.0803601105. Epub 2008 Jun 23.

7.

Self-assembling cannabinomimetics: supramolecular structures of N-alkyl amides.

Raduner S, Bisson W, Abagyan R, Altmann KH, Gertsch J.

J Nat Prod. 2007 Jun;70(6):1010-5. Epub 2007 May 11.

PMID:
17497806
8.

Stereoselective synthesis, natural occurrence and CB(2) receptor binding affinities of alkylamides from herbal medicines such as Echinacea sp.

Matovic N, Matthias A, Gertsch J, Raduner S, Bone KM, Lehmann RP, Devoss JJ.

Org Biomol Chem. 2007 Jan 7;5(1):169-74. Epub 2006 Nov 29.

PMID:
17164922
9.

New natural noncannabinoid ligands for cannabinoid type-2 (CB2) receptors.

Gertsch J, Raduner S, Altmann KH.

J Recept Signal Transduct Res. 2006;26(5-6):709-30. Review.

PMID:
17118807
10.

Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects.

Raduner S, Majewska A, Chen JZ, Xie XQ, Hamon J, Faller B, Altmann KH, Gertsch J.

J Biol Chem. 2006 May 19;281(20):14192-206. Epub 2006 Mar 17.

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