Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 27

1.

Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation.

Kano Y, Gebregiworgis T, Marshall CB, Radulovich N, Poon BPK, St-Germain J, Cook JD, Valencia-Sama I, Grant BMM, Herrera SG, Miao J, Raught B, Irwin MS, Lee JE, Yeh JJ, Zhang ZY, Tsao MS, Ikura M, Ohh M.

Nat Commun. 2019 Jan 15;10(1):224. doi: 10.1038/s41467-018-08115-8.

2.

Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer.

Gendoo DMA, Denroche RE, Zhang A, Radulovich N, Jang GH, Lemire M, Fischer S, Chadwick D, Lungu IM, Ibrahimov E, Cao PJ, Stein LD, Wilson JM, Bartlett JMS, Tsao MS, Dhani N, Hedley D, Gallinger S, Haibe-Kains B.

PLoS Comput Biol. 2019 Jan 10;15(1):e1006596. doi: 10.1371/journal.pcbi.1006596. eCollection 2019 Jan.

3.

Multiplexed Real-Time NMR GTPase Assay for Simultaneous Monitoring of Multiple Guanine Nucleotide Exchange Factor Activities from Human Cancer Cells and Organoids.

Gebregiworgis T, Marshall CB, Nishikawa T, Radulovich N, Sandí MJ, Fang Z, Rottapel R, Tsao MS, Ikura M.

J Am Chem Soc. 2018 Apr 4;140(13):4473-4476. doi: 10.1021/jacs.7b13703. Epub 2018 Mar 22.

PMID:
29543440
4.

Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer.

Navab R, Strumpf D, To C, Pasko E, Kim KS, Park CJ, Hai J, Liu J, Jonkman J, Barczyk M, Bandarchi B, Wang YH, Venkat K, Ibrahimov E, Pham NA, Ng C, Radulovich N, Zhu CQ, Pintilie M, Wang D, Lu A, Jurisica I, Walker GC, Gullberg D, Tsao MS.

Oncogene. 2016 Apr 14;35(15):1899-908. doi: 10.1038/onc.2015.254. Epub 2015 Jul 6.

5.

SOX15 and other SOX family members are important mediators of tumorigenesis in multiple cancer types.

Thu KL, Becker-Santos DD, Radulovich N, Pikor LA, Lam WL, Tsao MS.

Oncoscience. 2014 Jun 2;1(5):326-35. eCollection 2014.

6.

Coiled-coil domain containing 68 (CCDC68) demonstrates a tumor-suppressive role in pancreatic ductal adenocarcinoma.

Radulovich N, Leung L, Ibrahimov E, Navab R, Sakashita S, Zhu CQ, Kaufman E, Lockwood WW, Thu KL, Fedyshyn Y, Moffat J, Lam WL, Tsao MS.

Oncogene. 2015 Aug 6;34(32):4238-47. doi: 10.1038/onc.2014.357. Epub 2014 Nov 10.

7.

The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1.

Cullis J, Meiri D, Sandi MJ, Radulovich N, Kent OA, Medrano M, Mokady D, Normand J, Larose J, Marcotte R, Marshall CB, Ikura M, Ketela T, Moffat J, Neel BG, Gingras AC, Tsao MS, Rottapel R.

Cancer Cell. 2014 Feb 10;25(2):181-95. doi: 10.1016/j.ccr.2014.01.025.

8.

The Relative Value Unit in academic geriatrics: incentive or impediment?

Resnick NM, Radulovich N.

J Am Geriatr Soc. 2014 Mar;62(3):553-7. doi: 10.1111/jgs.12698. Epub 2014 Feb 10. Review.

9.

p120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line.

Organ SL, Hai J, Radulovich N, Marshall CB, Leung L, Sasazuki T, Shirasawa S, Zhu CQ, Navab R, Ikura M, Tsao MS.

PLoS One. 2014 Jan 21;9(1):e86103. doi: 10.1371/journal.pone.0086103. eCollection 2014.

10.

Loss of canonical Smad4 signaling promotes KRAS driven malignant transformation of human pancreatic duct epithelial cells and metastasis.

Leung L, Radulovich N, Zhu CQ, Wang D, To C, Ibrahimov E, Tsao MS.

PLoS One. 2013 Dec 27;8(12):e84366. doi: 10.1371/journal.pone.0084366. eCollection 2013.

11.

EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk.

Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TP, Selamat SA, Laird-Offringa IA, Liu P, Anderson M, You M, Tsao MS, Brown CJ, Bennewith KL, MacAulay CE, Karsan A, Gazdar AF, Lam S, Lam WL.

Oncogene. 2014 Sep 4;33(36):4464-73. doi: 10.1038/onc.2013.396. Epub 2013 Oct 7.

12.

SOX15 is a candidate tumor suppressor in pancreatic cancer with a potential role in Wnt/β-catenin signaling.

Thu KL, Radulovich N, Becker-Santos DD, Pikor LA, Pusic A, Lockwood WW, Lam WL, Tsao MS.

Oncogene. 2014 Jan 16;33(3):279-88. doi: 10.1038/onc.2012.595. Epub 2013 Jan 14.

PMID:
23318427
13.

Lipocalin2 promotes invasion, tumorigenicity and gemcitabine resistance in pancreatic ductal adenocarcinoma.

Leung L, Radulovich N, Zhu CQ, Organ S, Bandarchi B, Pintilie M, To C, Panchal D, Tsao MS.

PLoS One. 2012;7(10):e46677. doi: 10.1371/journal.pone.0046677. Epub 2012 Oct 4.

14.

Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer.

Navab R, Strumpf D, Bandarchi B, Zhu CQ, Pintilie M, Ramnarine VR, Ibrahimov E, Radulovich N, Leung L, Barczyk M, Panchal D, To C, Yun JJ, Der S, Shepherd FA, Jurisica I, Tsao MS.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7160-5. doi: 10.1073/pnas.1014506108. Epub 2011 Apr 7.

15.

Modified gateway system for double shRNA expression and Cre/lox based gene expression.

Radulovich N, Leung L, Tsao MS.

BMC Biotechnol. 2011 Mar 22;11:24. doi: 10.1186/1472-6750-11-24.

16.

Differential roles of cyclin D1 and D3 in pancreatic ductal adenocarcinoma.

Radulovich N, Pham NA, Strumpf D, Leung L, Xie W, Jurisica I, Tsao MS.

Mol Cancer. 2010 Feb 1;9:24. doi: 10.1186/1476-4598-9-24.

17.

Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts.

Schwock J, Dhani N, Cao MP, Zheng J, Clarkson R, Radulovich N, Navab R, Horn LC, Hedley DW.

Cancer Res. 2009 Jun 1;69(11):4750-9. doi: 10.1158/0008-5472.CAN-09-0454. Epub 2009 May 19.

18.

Absence of caspase-3 protects pancreatic {beta}-cells from c-Myc-induced apoptosis without leading to tumor formation.

Radziszewska A, Schroer SA, Choi D, Tajmir P, Radulovich N, Ho JC, Wang L, Liadis N, Hakem R, Tsao MS, Penn LZ, Evan GI, Woo M.

J Biol Chem. 2009 Apr 17;284(16):10947-56. doi: 10.1074/jbc.M806960200. Epub 2009 Feb 12.

19.

Human pancreatic duct epithelial cell model for KRAS transformation.

Radulovich N, Qian JY, Tsao MS.

Methods Enzymol. 2008;439:1-13. doi: 10.1016/S0076-6879(07)00401-6.

PMID:
18374152
20.

Gab1 but not Grb2 mediates tumor progression in Met overexpressing colorectal cancer cells.

Seiden-Long I, Navab R, Shih W, Li M, Chow J, Zhu CQ, Radulovich N, Saucier C, Tsao MS.

Carcinogenesis. 2008 Mar;29(3):647-55. doi: 10.1093/carcin/bgn009. Epub 2008 Jan 12.

PMID:
18192688
21.

Transcriptional targets of hepatocyte growth factor signaling and Ki-ras oncogene activation in colorectal cancer.

Seiden-Long IM, Brown KR, Shih W, Wigle DA, Radulovich N, Jurisica I, Tsao MS.

Oncogene. 2006 Jan 5;25(1):91-102.

PMID:
16158056
22.

Stability and heterogeneity of expression profiles in lung cancer specimens harvested following surgical resection.

Blackhall FH, Pintilie M, Wigle DA, Jurisica I, Liu N, Radulovich N, Johnston MR, Keshavjee S, Tsao MS.

Neoplasia. 2004 Nov-Dec;6(6):761-7.

23.

Overexpression of G1-S cyclins and cyclin-dependent kinases during multistage human pancreatic duct cell carcinogenesis.

Al-Aynati MM, Radulovich N, Ho J, Tsao MS.

Clin Cancer Res. 2004 Oct 1;10(19):6598-605.

24.

Modeling of lung cancer by an orthotopically growing H460SM variant cell line reveals novel candidate genes for systemic metastasis.

Liu J, Blackhall F, Seiden-Long I, Jurisica I, Navab R, Liu N, Radulovich N, Wigle D, Sultan M, Hu J, Tsao MS, Johnston MR.

Oncogene. 2004 Aug 19;23(37):6316-24.

PMID:
15247903
25.

Epithelial-cadherin and beta-catenin expression changes in pancreatic intraepithelial neoplasia.

Al-Aynati MM, Radulovich N, Riddell RH, Tsao MS.

Clin Cancer Res. 2004 Feb 15;10(4):1235-40.

26.

Novel candidate tumor marker genes for lung adenocarcinoma.

Wang KK, Liu N, Radulovich N, Wigle DA, Johnston MR, Shepherd FA, Minden MD, Tsao MS.

Oncogene. 2002 Oct 24;21(49):7598-604.

27.

Molecular profiling of non-small cell lung cancer and correlation with disease-free survival.

Wigle DA, Jurisica I, Radulovich N, Pintilie M, Rossant J, Liu N, Lu C, Woodgett J, Seiden I, Johnston M, Keshavjee S, Darling G, Winton T, Breitkreutz BJ, Jorgenson P, Tyers M, Shepherd FA, Tsao MS.

Cancer Res. 2002 Jun 1;62(11):3005-8.

Supplemental Content

Loading ...
Support Center