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Items: 1 to 50 of 188

1.

AMPK promotes survival of c-Myc-positive melanoma cells by suppressing oxidative stress.

Kfoury A, Armaro M, Collodet C, Sordet-Dessimoz J, Giner MP, Christen S, Moco S, Leleu M, de Leval L, Koch U, Trumpp A, Sakamoto K, Beermann F, Radtke F.

EMBO J. 2018 Mar 1;37(5). pii: e97673. doi: 10.15252/embj.201797673. Epub 2018 Feb 12.

PMID:
29440228
2.

Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone.

Engler A, Rolando C, Giachino C, Saotome I, Erni A, Brien C, Zhang R, Zimber-Strobl U, Radtke F, Artavanis-Tsakonas S, Louvi A, Taylor V.

Cell Rep. 2018 Jan 23;22(4):992-1002. doi: 10.1016/j.celrep.2017.12.094. Epub 2018 Jan 28.

3.

Nu-DESC DK: the Danish version of the nursing delirium screening scale (nu-DESC).

Hägi-Pedersen D, Thybo KH, Holgersen TH, Jensen JJ, Gaudreau JD, Radtke FM.

BMC Nurs. 2017 Dec 29;16:75. doi: 10.1186/s12912-017-0271-x. eCollection 2017.

4.

Modulating Neuroinflammation to Treat Neuropsychiatric Disorders.

Radtke FA, Chapman G, Hall J, Syed YA.

Biomed Res Int. 2017;2017:5071786. doi: 10.1155/2017/5071786. Epub 2017 Oct 18. Review.

5.

Notch1 haploinsufficiency causes ascending aortic aneurysms in mice.

Koenig SN, LaHaye S, Feller JD, Rowland P, Hor KN, Trask AJ, Janssen PM, Radtke F, Lilly B, Garg V.

JCI Insight. 2017 Nov 2;2(21). pii: 91353. doi: 10.1172/jci.insight.91353. [Epub ahead of print]

6.

Signalling strength determines proapoptotic functions of STING.

Gulen MF, Koch U, Haag SM, Schuler F, Apetoh L, Villunger A, Radtke F, Ablasser A.

Nat Commun. 2017 Sep 5;8(1):427. doi: 10.1038/s41467-017-00573-w.

7.

Acetylcholinesterase and butyrylcholinesterase in cardiosurgical patients with postoperative delirium.

John M, Ely EW, Halfkann D, Schoen J, Sedemund-Adib B, Klotz S, Radtke F, Stehr S, Hueppe M.

J Intensive Care. 2017 May 26;5:29. doi: 10.1186/s40560-017-0224-1. eCollection 2017.

8.

Corrigendum: Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Häger C, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy KM, Adams RH, Weber C, Limbourg FP.

Nat Commun. 2017 May 3;8:15486. doi: 10.1038/ncomms15486. No abstract available.

9.

Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.

Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Huang AY, Brennan TV, Bishop DK, Ludewig B, Siebel CW, Radtke F, Luther SA, Maillard I.

J Clin Invest. 2017 Apr 3;127(4):1574-1588. doi: 10.1172/JCI89535. Epub 2017 Mar 20.

10.

The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool.

Lawal RA, Zhou X, Batey K, Hoffman CM, Georger MA, Radtke F, Hilton MJ, Xing L, Frisch BJ, Calvi LM.

J Bone Miner Res. 2017 Jun;32(6):1320-1331. doi: 10.1002/jbmr.3106. Epub 2017 Mar 9.

11.

Corneal epithelial stem cells and their niche at a glance.

Nowell CS, Radtke F.

J Cell Sci. 2017 Mar 15;130(6):1021-1025. doi: 10.1242/jcs.198119. Epub 2017 Feb 15. Review.

12.

European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium.

Aldecoa C, Bettelli G, Bilotta F, Sanders RD, Audisio R, Borozdina A, Cherubini A, Jones C, Kehlet H, MacLullich A, Radtke F, Riese F, Slooter AJ, Veyckemans F, Kramer S, Neuner B, Weiss B, Spies CD.

Eur J Anaesthesiol. 2017 Apr;34(4):192-214. doi: 10.1097/EJA.0000000000000594.

PMID:
28187050
13.

Notch as a tumour suppressor.

Nowell CS, Radtke F.

Nat Rev Cancer. 2017 Mar;17(3):145-159. doi: 10.1038/nrc.2016.145. Epub 2017 Feb 3. Review.

PMID:
28154375
14.

Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner.

Coutaz M, Hurrell BP, Auderset F, Wang H, Siegert S, Eberl G, Ho PC, Radtke F, Tacchini-Cottier F.

Sci Rep. 2016 Dec 15;6:39117. doi: 10.1038/srep39117.

15.

Myeloid DLL4 Does Not Contribute to the Pathogenesis of Non-Alcoholic Steatohepatitis in Ldlr-/- Mice.

Jeurissen ML, Walenbergh SM, Houben T, Hendrikx T, Li J, Oligschlaeger Y, van Gorp PJ, Gijbels MJ, Bitorina A, Nessel I, Radtke F, Vooijs M, Theys J, Shiri-Sverdlov R.

PLoS One. 2016 Nov 29;11(11):e0167199. doi: 10.1371/journal.pone.0167199. eCollection 2016.

16.

Notch1-WISP-1 axis determines the regulatory role of mesenchymal stem cell-derived stromal fibroblasts in melanoma metastasis.

Shao H, Cai L, Moller M, Issac B, Zhang L, Owyong M, Moscowitz AE, Vazquez-Padron R, Radtke F, Liu ZJ.

Oncotarget. 2016 Nov 29;7(48):79262-79273. doi: 10.18632/oncotarget.13021.

17.

No convincing association between post-operative delirium and post-operative cognitive dysfunction: a secondary analysis.

Franck M, Nerlich K, Neuner B, Schlattmann P, Brockhaus WR, Spies CD, Radtke FM.

Acta Anaesthesiol Scand. 2016 Nov;60(10):1404-1414. doi: 10.1111/aas.12779. Epub 2016 Aug 31.

PMID:
27578364
18.

Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy KM, Adams RH, Weber C, Limbourg FP.

Nat Commun. 2016 Aug 31;7:12597. doi: 10.1038/ncomms12597.

19.

How can postoperative delirium be predicted in advance? A secondary analysis comparing three methods of early assessment in elderly patients.

Stukenberg S, Franck M, Spies CD, Neuner B, Myers I, Radtke FM.

Minerva Anestesiol. 2016 Jul;82(7):751-9.

20.

Notch Signaling Regulates the Homeostasis of Tissue-Restricted Innate-like T Cells.

Chennupati V, Koch U, Coutaz M, Scarpellino L, Tacchini-Cottier F, Luther SA, Radtke F, Zehn D, MacDonald HR.

J Immunol. 2016 Aug 1;197(3):771-82. doi: 10.4049/jimmunol.1501675. Epub 2016 Jun 20.

21.

Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract.

Koenig SN, Bosse K, Majumdar U, Bonachea EM, Radtke F, Garg V.

J Am Heart Assoc. 2016 Apr 22;5(4). pii: e003075. doi: 10.1161/JAHA.115.003075.

22.

Linking inflammation and mechanotransduction in stem cell regulation.

Radtke F, Nowell CS.

Cell Cycle. 2016 Jun 2;15(11):1393-4. doi: 10.1080/15384101.2016.1171645. Epub 2016 Apr 6. No abstract available.

23.

Patients prone for postoperative delirium: preoperative assessment, perioperative prophylaxis, postoperative treatment.

Guenther U, Riedel L, Radtke FM.

Curr Opin Anaesthesiol. 2016 Jun;29(3):384-90. doi: 10.1097/ACO.0000000000000327. Review.

PMID:
26905874
24.

Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction.

Nowell CS, Odermatt PD, Azzolin L, Hohnel S, Wagner EF, Fantner GE, Lutolf MP, Barrandon Y, Piccolo S, Radtke F.

Nat Cell Biol. 2016 Feb;18(2):168-80. doi: 10.1038/ncb3290. Epub 2015 Dec 21.

PMID:
26689676
25.

Notch1 Pathway Activity Determines the Regulatory Role of Cancer-Associated Fibroblasts in Melanoma Growth and Invasion.

Shao H, Kong R, Ferrari ML, Radtke F, Capobianco AJ, Liu ZJ.

PLoS One. 2015 Nov 12;10(11):e0142815. doi: 10.1371/journal.pone.0142815. eCollection 2015.

26.

DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport.

Bernier-Latmani J, Cisarovsky C, Demir CS, Bruand M, Jaquet M, Davanture S, Ragusa S, Siegert S, Dormond O, Benedito R, Radtke F, Luther SA, Petrova TV.

J Clin Invest. 2015 Nov 3;125(12):4572-86. doi: 10.1172/JCI82045.

27.

Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 2: consensus statement for anaesthesia practice.

Feldheiser A, Aziz O, Baldini G, Cox BP, Fearon KC, Feldman LS, Gan TJ, Kennedy RH, Ljungqvist O, Lobo DN, Miller T, Radtke FF, Ruiz Garces T, Schricker T, Scott MJ, Thacker JK, Ytrebø LM, Carli F.

Acta Anaesthesiol Scand. 2016 Mar;60(3):289-334. doi: 10.1111/aas.12651. Epub 2015 Oct 30. Review.

28.

Phage Selection of Bicyclic Peptide Ligands of the Notch1 Receptor.

Urech-Varenne C, Radtke F, Heinis C.

ChemMedChem. 2015 Oct;10(10):1754-61. doi: 10.1002/cmdc.201500261. Epub 2015 Aug 25.

PMID:
26381087
29.

Dicer1 imparts essential survival cues in Notch-driven T-ALL via miR-21-mediated tumor suppressor Pdcd4 repression.

Junker F, Chabloz A, Koch U, Radtke F.

Blood. 2015 Aug 20;126(8):993-1004. doi: 10.1182/blood-2014-12-618892. Epub 2015 May 15.

30.

Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch.

López-Arribillaga E, Rodilla V, Pellegrinet L, Guiu J, Iglesias M, Roman AC, Gutarra S, González S, Muñoz-Cánoves P, Fernández-Salguero P, Radtke F, Bigas A, Espinosa L.

Development. 2015 Jan 1;142(1):41-50. doi: 10.1242/dev.107714. Epub 2014 Dec 5.

31.

Delirium, sedation and analgesia in the intensive care unit: a multinational, two-part survey among intensivists.

Luetz A, Balzer F, Radtke FM, Jones C, Citerio G, Walder B, Weiss B, Wernecke KD, Spies C.

PLoS One. 2014 Nov 14;9(11):e110935. doi: 10.1371/journal.pone.0110935. eCollection 2014.

32.

Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses.

Fasnacht N, Huang HY, Koch U, Favre S, Auderset F, Chai Q, Onder L, Kallert S, Pinschewer DD, MacDonald HR, Tacchini-Cottier F, Ludewig B, Luther SA, Radtke F.

J Exp Med. 2014 Oct 20;211(11):2265-79. doi: 10.1084/jem.20132528. Epub 2014 Oct 13.

33.

Tumor vessel normalization by chloroquine independent of autophagy.

Maes H, Kuchnio A, Peric A, Moens S, Nys K, De Bock K, Quaegebeur A, Schoors S, Georgiadou M, Wouters J, Vinckier S, Vankelecom H, Garmyn M, Vion AC, Radtke F, Boulanger C, Gerhardt H, Dejana E, Dewerchin M, Ghesquière B, Annaert W, Agostinis P, Carmeliet P.

Cancer Cell. 2014 Aug 11;26(2):190-206. doi: 10.1016/j.ccr.2014.06.025.

34.

Postoperative delirium is an independent risk factor for posttraumatic stress disorder in the elderly patient: a prospective observational study.

Drews T, Franck M, Radtke FM, Weiss B, Krampe H, Brockhaus WR, Winterer G, Spies CD.

Eur J Anaesthesiol. 2015 Mar;32(3):147-51. doi: 10.1097/EJA.0000000000000107.

PMID:
24979586
35.

Derivation of traceable and transplantable photoreceptors from mouse embryonic stem cells.

Decembrini S, Koch U, Radtke F, Moulin A, Arsenijevic Y.

Stem Cell Reports. 2014 May 22;2(6):853-65. doi: 10.1016/j.stemcr.2014.04.010. eCollection 2014 Jun 3.

36.

Notch signaling in the pigmented epithelium of the anterior eye segment promotes ciliary body development at the expense of iris formation.

Sarode B, Nowell CS, Ihm J, Kostic C, Arsenijevic Y, Moulin AP, Schorderet DF, Beermann F, Radtke F.

Pigment Cell Melanoma Res. 2014 Jul;27(4):580-9. doi: 10.1111/pcmr.12236. Epub 2014 Apr 7.

PMID:
24628886
37.

Cutaneous Notch signaling in health and disease.

Nowell C, Radtke F.

Cold Spring Harb Perspect Med. 2013 Dec 1;3(12):a017772. doi: 10.1101/cshperspect.a017772. Review.

38.

[Comments on: long-term cognitive impairment after intensive care therapy].

Franck M, Radtke FM.

Anaesthesist. 2013 Dec;62(12):1020-2. doi: 10.1007/s00101-013-2273-8. German. No abstract available.

PMID:
24292124
39.

Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53.

Licciulli S, Avila JL, Hanlon L, Troutman S, Cesaroni M, Kota S, Keith B, Simon MC, Puré E, Radtke F, Capobianco AJ, Kissil JL.

Cancer Res. 2013 Oct 1;73(19):5974-84. doi: 10.1158/0008-5472.CAN-13-1384. Epub 2013 Aug 13.

40.

Notch signaling regulates follicular helper T cell differentiation.

Auderset F, Schuster S, Fasnacht N, Coutaz M, Charmoy M, Koch U, Favre S, Wilson A, Trottein F, Alexander J, Luther SA, MacDonald HR, Radtke F, Tacchini-Cottier F.

J Immunol. 2013 Sep 1;191(5):2344-50. doi: 10.4049/jimmunol.1300643. Epub 2013 Aug 5.

41.

Alzheimer's disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production.

Dimitrov M, Alattia JR, Lemmin T, Lehal R, Fligier A, Houacine J, Hussain I, Radtke F, Dal Peraro M, Beher D, Fraering PC.

Nat Commun. 2013;4:2246. doi: 10.1038/ncomms3246.

PMID:
23907250
42.

DL4-mediated Notch signaling is required for the development of fetal αβ and γδ T cells.

Ferrero I, Koch U, Claudinot S, Favre S, Radtke F, Luther SA, MacDonald HR.

Eur J Immunol. 2013 Nov;43(11):2845-53. doi: 10.1002/eji.201343527. Epub 2013 Aug 25.

43.

Notch1 regulates angio-supportive bone marrow-derived cells in mice: relevance to chemoresistance.

Roodhart JM, He H, Daenen LG, Monvoisin A, Barber CL, van Amersfoort M, Hofmann JJ, Radtke F, Lane TF, Voest EE, Iruela-Arispe ML.

Blood. 2013 Jul 4;122(1):143-53. doi: 10.1182/blood-2012-11-459347. Epub 2013 May 20.

44.

Regulation of innate and adaptive immunity by Notch.

Radtke F, MacDonald HR, Tacchini-Cottier F.

Nat Rev Immunol. 2013 Jun;13(6):427-37. doi: 10.1038/nri3445. Epub 2013 May 13. Review.

PMID:
23665520
45.

Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction.

Radtke FM, Franck M, Lendner J, Krüger S, Wernecke KD, Spies CD.

Br J Anaesth. 2013 Jun;110 Suppl 1:i98-105. doi: 10.1093/bja/aet055. Epub 2013 Mar 28.

46.

Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength.

Van de Walle I, Waegemans E, De Medts J, De Smet G, De Smedt M, Snauwaert S, Vandekerckhove B, Kerre T, Leclercq G, Plum J, Gridley T, Wang T, Koch U, Radtke F, Taghon T.

J Exp Med. 2013 Apr 8;210(4):683-97. doi: 10.1084/jem.20121798. Epub 2013 Mar 25.

47.

Jagged1 is the major regulator of Notch-dependent cell fate in proximal airways.

Zhang S, Loch AJ, Radtke F, Egan SE, Xu K.

Dev Dyn. 2013 Jun;242(6):678-86. doi: 10.1002/dvdy.23965. Epub 2013 Apr 29.

48.

Stem cells living with a Notch.

Koch U, Lehal R, Radtke F.

Development. 2013 Feb;140(4):689-704. doi: 10.1242/dev.080614. Review.

49.

From the cradle to the work place: pleitropic roles of Notch in immunity. (Preface).

Radtke F.

Curr Top Microbiol Immunol. 2012;360:v-vi. No abstract available.

PMID:
23230601
50.

The Notch pathway controls fibrotic and regenerative repair in the adult heart.

Nemir M, Metrich M, Plaisance I, Lepore M, Cruchet S, Berthonneche C, Sarre A, Radtke F, Pedrazzini T.

Eur Heart J. 2014 Aug 21;35(32):2174-85. doi: 10.1093/eurheartj/ehs269. Epub 2012 Nov 19.

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