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Items: 6


Centrosomal abnormalities characterize human and rodent cystic cholangiocytes and are associated with Cdc25A overexpression.

Masyuk TV, Lee SO, Radtke BN, Stroope AJ, Huang B, Banales JM, Masyuk AI, Splinter PL, Gradilone SA, Gajdos GB, LaRusso NF.

Am J Pathol. 2014 Jan;184(1):110-21. doi: 10.1016/j.ajpath.2013.09.021. Epub 2013 Nov 7.


Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling.

Masyuk AI, Huang BQ, Radtke BN, Gajdos GB, Splinter PL, Masyuk TV, Gradilone SA, LaRusso NF.

Am J Physiol Gastrointest Liver Physiol. 2013 Jun 1;304(11):G1013-24. doi: 10.1152/ajpgi.00383.2012. Epub 2013 Apr 11.


HDAC6 inhibition restores ciliary expression and decreases tumor growth.

Gradilone SA, Radtke BN, Bogert PS, Huang BQ, Gajdos GB, LaRusso NF.

Cancer Res. 2013 Apr 1;73(7):2259-70. doi: 10.1158/0008-5472.CAN-12-2938. Epub 2013 Jan 31.


Pasireotide is more effective than octreotide in reducing hepatorenal cystogenesis in rodents with polycystic kidney and liver diseases.

Masyuk TV, Radtke BN, Stroope AJ, Banales JM, Gradilone SA, Huang B, Masyuk AI, Hogan MC, Torres VE, Larusso NF.

Hepatology. 2013 Jul;58(1):409-21. doi: 10.1002/hep.26140. Epub 2013 Mar 6.


Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease.

Masyuk TV, Radtke BN, Stroope AJ, Banales JM, Masyuk AI, Gradilone SA, Gajdos GB, Chandok N, Bakeberg JL, Ward CJ, Ritman EL, Kiyokawa H, LaRusso NF.

Gastroenterology. 2012 Mar;142(3):622-633.e4. doi: 10.1053/j.gastro.2011.11.036. Epub 2011 Dec 7.


Activation of Trpv4 reduces the hyperproliferative phenotype of cystic cholangiocytes from an animal model of ARPKD.

Gradilone SA, Masyuk TV, Huang BQ, Banales JM, Lehmann GL, Radtke BN, Stroope A, Masyuk AI, Splinter PL, LaRusso NF.

Gastroenterology. 2010 Jul;139(1):304-14.e2. doi: 10.1053/j.gastro.2010.04.010. Epub 2010 Apr 14.

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