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Items: 13


Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity.

Preite S, Cannons JL, Radtke AJ, Vujkovic-Cvijin I, Gomez-Rodriguez J, Volpi S, Huang B, Cheng J, Collins N, Reilley J, Handon R, Dobbs K, Huq L, Raman I, Zhu C, Li QZ, Li MO, Pittaluga S, Uzel G, Notarangelo LD, Belkaid Y, Germain RN, Schwartzberg PL.

Nat Immunol. 2018 Sep;19(9):986-1000. doi: 10.1038/s41590-018-0182-3. Epub 2018 Aug 20.


Spatial distribution and function of T follicular regulatory cells in human lymph nodes.

Sayin I, Radtke AJ, Vella LA, Jin W, Wherry EJ, Buggert M, Betts MR, Herati RS, Germain RN, Canaday DH.

J Exp Med. 2018 Jun 4;215(6):1531-1542. doi: 10.1084/jem.20171940. Epub 2018 May 16.


Co-stimulatory function in primary germinal center responses: CD40 and B7 are required on distinct antigen-presenting cells.

Watanabe M, Fujihara C, Radtke AJ, Chiang YJ, Bhatia S, Germain RN, Hodes RJ.

J Exp Med. 2017 Sep 4;214(9):2795-2810. doi: 10.1084/jem.20161955. Epub 2017 Aug 2.


Adjuvant and carrier protein-dependent T-cell priming promotes a robust antibody response against the Plasmodium falciparum Pfs25 vaccine candidate.

Radtke AJ, Anderson CF, Riteau N, Rausch K, Scaria P, Kelnhofer ER, Howard RF, Sher A, Germain RN, Duffy P.

Sci Rep. 2017 Jan 16;7:40312. doi: 10.1038/srep40312.


Water-in-Oil-Only Adjuvants Selectively Promote T Follicular Helper Cell Polarization through a Type I IFN and IL-6-Dependent Pathway.

Riteau N, Radtke AJ, Shenderov K, Mittereder L, Oland SD, Hieny S, Jankovic D, Sher A.

J Immunol. 2016 Nov 15;197(10):3884-3893. Epub 2016 Oct 17.


Development and Assessment of Transgenic Rodent Parasites for the Preclinical Evaluation of Malaria Vaccines.

Espinosa DA, Radtke AJ, Zavala F.

Methods Mol Biol. 2016;1403:583-601. doi: 10.1007/978-1-4939-3387-7_33.


From the draining lymph node to the liver: the induction and effector mechanisms of malaria-specific CD8+ T cells.

Radtke AJ, Tse SW, Zavala F.

Semin Immunopathol. 2015 May;37(3):211-20. doi: 10.1007/s00281-015-0479-3. Epub 2015 Apr 28. Review.


Lymph-node resident CD8α+ dendritic cells capture antigens from migratory malaria sporozoites and induce CD8+ T cell responses.

Radtke AJ, Kastenmüller W, Espinosa DA, Gerner MY, Tse SW, Sinnis P, Germain RN, Zavala FP, Cockburn IA.

PLoS Pathog. 2015 Feb 6;11(2):e1004637. doi: 10.1371/journal.ppat.1004637. eCollection 2015 Feb.


The chemokine receptor CXCR6 is required for the maintenance of liver memory CD8⁺ T cells specific for infectious pathogens.

Tse SW, Radtke AJ, Espinosa DA, Cockburn IA, Zavala F.

J Infect Dis. 2014 Nov 1;210(9):1508-16. doi: 10.1093/infdis/jiu281. Epub 2014 May 13.


TLR3 deficiency induces chronic inflammatory cardiomyopathy in resistant mice following coxsackievirus B3 infection: role for IL-4.

Abston ED, Coronado MJ, Bucek A, Onyimba JA, Brandt JE, Frisancho JA, Kim E, Bedja D, Sung YK, Radtke AJ, Gabrielson KL, Mitzner W, Fairweather D.

Am J Physiol Regul Integr Comp Physiol. 2013 Feb 15;304(4):R267-77. doi: 10.1152/ajpregu.00516.2011. Epub 2012 Dec 19.


Regulation of anti-Plasmodium immunity by a LITAF-like transcription factor in the malaria vector Anopheles gambiae.

Smith RC, Eappen AG, Radtke AJ, Jacobs-Lorena M.

PLoS Pathog. 2012;8(10):e1002965. doi: 10.1371/journal.ppat.1002965. Epub 2012 Oct 18.


Induction and maintenance of protective CD8+ T cells against malaria liver stages: implications for vaccine development.

Tse SW, Radtke AJ, Zavala F.

Mem Inst Oswaldo Cruz. 2011 Aug;106 Suppl 1:172-8. Review.


Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo.

Cockburn IA, Tse SW, Radtke AJ, Srinivasan P, Chen YC, Sinnis P, Zavala F.

PLoS Pathog. 2011 Mar;7(3):e1001318. doi: 10.1371/journal.ppat.1001318. Epub 2011 Mar 17.

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