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Items: 8


Control of Acinetobacter baumannii outbreak in the neonatal intensive care unit in Latvia: whole-genome sequencing powered investigation and closure of the ward.

Gramatniece A, Silamikelis I, Zahare I, Urtans V, Zahare I, Dimina E, Saule M, Balode A, Radovica-Spalvina I, Klovins J, Fridmanis D, Dumpis U.

Antimicrob Resist Infect Control. 2019 May 22;8:84. doi: 10.1186/s13756-019-0537-z. eCollection 2019.


Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals.

Elbere I, Silamikelis I, Ustinova M, Kalnina I, Zaharenko L, Peculis R, Konrade I, Ciuculete DM, Zhukovsky C, Gudra D, Radovica-Spalvina I, Fridmanis D, Pirags V, Schiöth HB, Klovins J.

Clin Epigenetics. 2018 Dec 13;10(1):156. doi: 10.1186/s13148-018-0593-x.


Association of metformin administration with gut microbiome dysbiosis in healthy volunteers.

Elbere I, Kalnina I, Silamikelis I, Konrade I, Zaharenko L, Sekace K, Radovica-Spalvina I, Fridmanis D, Gudra D, Pirags V, Klovins J.

PLoS One. 2018 Sep 27;13(9):e0204317. doi: 10.1371/journal.pone.0204317. eCollection 2018.


A widely used sampling device in colorectal cancer screening programmes allows for large-scale microbiome studies.

Gudra D, Shoaie S, Fridmanis D, Klovins J, Wefer H, Silamikelis I, Peculis R, Kalnina I, Elbere I, Radovica-Spalvina I, Hultcrantz R, Šķenders Ģ, Leja M, Engstrand L.

Gut. 2019 Sep;68(9):1723-1725. doi: 10.1136/gutjnl-2018-316225. Epub 2018 Sep 21. No abstract available.


The effects of ibuprofen on activated sludge: Shift in bacterial community structure and resistance to ciprofloxacin.

Davids M, Gudra D, Radovica-Spalvina I, Fridmanis D, Bartkevics V, Muter O.

J Hazard Mater. 2017 Oct 15;340:291-299. doi: 10.1016/j.jhazmat.2017.06.065. Epub 2017 Jun 28.


Removal of pharmaceuticals from municipal wastewaters at laboratory scale by treatment with activated sludge and biostimulation.

Muter O, P Erkons I, Selga T, Berzins A, Gudra D, Radovica-Spalvina I, Fridmanis D, Bartkevics V.

Sci Total Environ. 2017 Apr 15;584-585:402-413. doi: 10.1016/j.scitotenv.2017.01.023. Epub 2017 Jan 24.


Single nucleotide polymorphisms in the intergenic region between metformin transporter OCT2 and OCT3 coding genes are associated with short-term response to metformin monotherapy in type 2 diabetes mellitus patients.

Zaharenko L, Kalnina I, Geldnere K, Konrade I, Grinberga S, Židzik J, Javorský M, Lejnieks A, Nikitina-Zake L, Fridmanis D, Peculis R, Radovica-Spalvina I, Hartmane D, Pugovics O, Tkáč I, Klimčáková L, Pīrāgs V, Klovins J.

Eur J Endocrinol. 2016 Dec;175(6):531-540. Epub 2016 Sep 8.


Next-generation-sequencing-based identification of familial hypercholesterolemia-related mutations in subjects with increased LDL-C levels in a latvian population.

Radovica-Spalvina I, Latkovskis G, Silamikelis I, Fridmanis D, Elbere I, Ventins K, Ozola G, Erglis A, Klovins J.

BMC Med Genet. 2015 Sep 28;16:86. doi: 10.1186/s12881-015-0230-x.

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