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Items: 17


In vivo investigation of hyperpolarized [1,3-13C2]acetoacetate as a metabolic probe in normal brain and in glioma.

Najac C, Radoul M, Le Page LM, Batsios G, Subramani E, Viswanath P, Gillespie AM, Ronen SM.

Sci Rep. 2019 Mar 4;9(1):3402. doi: 10.1038/s41598-019-39677-2.


HDAC inhibition in glioblastoma monitored by hyperpolarized 13 C MRSI.

Radoul M, Najac C, Viswanath P, Mukherjee J, Kelly M, Gillespie AM, Chaumeil MM, Eriksson P, Delos Santos R, Pieper RO, Ronen SM.

NMR Biomed. 2019 Feb;32(2):e4044. doi: 10.1002/nbm.4044. Epub 2018 Dec 18.


Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner.

Viswanath P, Radoul M, Izquierdo-Garcia JL, Luchman HA, Gregory Cairncross J, Pieper RO, Phillips JJ, Ronen SM.

Cancer Metab. 2018 Apr 3;6:3. doi: 10.1186/s40170-018-0178-3. eCollection 2018.


2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas.

Viswanath P, Radoul M, Izquierdo-Garcia JL, Ong WQ, Luchman HA, Cairncross JG, Huang B, Pieper RO, Phillips JJ, Ronen SM.

Cancer Res. 2018 May 1;78(9):2290-2304. doi: 10.1158/0008-5472.CAN-17-2926. Epub 2018 Jan 22.


Correction to Thiolate Spin Population of Type I Copper in Azurin Derived from 33S Hyperfine Coupling.

Cohen MR, Mendelman N, Radoul M, Wilson TD, Savelieff MG, Zimmermann H, Kaminker I, Feintuch A, Lu Y, Goldfarb D.

Inorg Chem. 2017 Aug 21;56(16):10117. doi: 10.1021/acs.inorgchem.7b01753. Epub 2017 Aug 4. No abstract available.


Thiolate Spin Population of Type I Copper in Azurin Derived from 33S Hyperfine Coupling.

Ramirez Cohen M, Mendelman N, Radoul M, Wilson TD, Savelieff MG, Zimmermann H, Kaminker I, Feintuch A, Lu Y, Goldfarb D.

Inorg Chem. 2017 Jun 5;56(11):6163-6174. doi: 10.1021/acs.inorgchem.7b00167. Epub 2017 May 16. Erratum in: Inorg Chem. 2017 Aug 21;56(16):10117.


Hyperpolarized (13)C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring.

Chaumeil MM, Radoul M, Najac C, Eriksson P, Viswanath P, Blough MD, Chesnelong C, Luchman HA, Cairncross JG, Ronen SM.

Neuroimage Clin. 2016 Jun 23;12:180-9. doi: 10.1016/j.nicl.2016.06.018. eCollection 2016.


Genetic manipulation of iron biomineralization enhances MR relaxivity in a ferritin-M6A chimeric complex.

Radoul M, Lewin L, Cohen B, Oren R, Popov S, Davidov G, Vandsburger MH, Harmelin A, Bitton R, Greneche JM, Neeman M, Zarivach R.

Sci Rep. 2016 May 23;6:26550. doi: 10.1038/srep26550.


MR Studies of Glioblastoma Models Treated with Dual PI3K/mTOR Inhibitor and Temozolomide:Metabolic Changes Are Associated with Enhanced Survival.

Radoul M, Chaumeil MM, Eriksson P, Wang AS, Phillips JJ, Ronen SM.

Mol Cancer Ther. 2016 May;15(5):1113-22. doi: 10.1158/1535-7163.MCT-15-0769. Epub 2016 Feb 16.


IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.

Izquierdo-Garcia JL, Viswanath P, Eriksson P, Cai L, Radoul M, Chaumeil MM, Blough M, Luchman HA, Weiss S, Cairncross JG, Phillips JJ, Pieper RO, Ronen SM.

Cancer Res. 2015 Aug 1;75(15):2999-3009. doi: 10.1158/0008-5472.CAN-15-0840. Epub 2015 Jun 4.


Ovarian carcinoma: quantitative biexponential MR imaging relaxometry reveals the dynamic recruitment of ferritin-expressing fibroblasts to the angiogenic rim of tumors.

Vandsburger MH, Radoul M, Addadi Y, Mpofu S, Cohen B, Eilam R, Neeman M.

Radiology. 2013 Sep;268(3):790-801. doi: 10.1148/radiol.13122053. Epub 2013 Jun 25.


MRI reporter genes: applications for imaging of cell survival, proliferation, migration and differentiation.

Vandsburger MH, Radoul M, Cohen B, Neeman M.

NMR Biomed. 2013 Jul;26(7):872-84. doi: 10.1002/nbm.2869. Epub 2012 Dec 6. Review.


Solvent accessibility in the distal heme pocket of the nitrosyl d(1)-heme complex of Pseudomonas stutzeri cd(1) nitrite reductase.

Radoul M, Barak Y, Rinaldo S, CutruzzolĂ  F, Pecht I, Goldfarb D.

Biochemistry. 2012 Nov 13;51(45):9192-201. doi: 10.1021/bi3011237. Epub 2012 Nov 2.


Dynamic hydrogen-bonding network in the distal pocket of the nitrosyl complex of Pseudomonas aeruginosa cd1 nitrite reductase.

Radoul M, Bykov D, Rinaldo S, CutruzzolĂ  F, Neese F, Goldfarb D.

J Am Chem Soc. 2011 Mar 9;133(9):3043-55. doi: 10.1021/ja109688w. Epub 2011 Feb 10.


Revisiting the nitrosyl complex of myoglobin by high-field pulse EPR spectroscopy and quantum mechanical calculations.

Radoul M, Sundararajan M, Potapov A, Riplinger C, Neese F, Goldfarb D.

Phys Chem Chem Phys. 2010 Jul 14;12(26):7276-89. doi: 10.1039/c000652a. Epub 2010 May 20.


Heme d1 nitrosyl complex of cd1 nitrite reductase studied by high-field-pulse electron paramagnetic resonance spectroscopy.

Radoul M, Centola F, Rinaldo S, CutruzzolĂ  F, Pecht I, Goldfarb D.

Inorg Chem. 2009 May 4;48(9):3913-5. doi: 10.1021/ic802355y.


HYSCORE and DEER with an upgraded 95GHz pulse EPR spectrometer.

Goldfarb D, Lipkin Y, Potapov A, Gorodetsky Y, Epel B, Raitsimring AM, Radoul M, Kaminker I.

J Magn Reson. 2008 Sep;194(1):8-15. doi: 10.1016/j.jmr.2008.05.019. Epub 2008 May 29.


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