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Items: 15

1.

2-(2-Hydroxy-3-alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors.

Mackman RL, Hui HC, Breitenbucher JG, Katz BA, Luong C, Martelli A, McGee D, Radika K, Sendzik M, Spencer JR, Sprengeler PA, Tario J, Verner E, Wang J.

Bioorg Med Chem Lett. 2002 Aug 5;12(15):2019-22.

PMID:
12113832
2.

Development of serine protease inhibitors displaying a multicentered short (<2.3 A) hydrogen bond binding mode: inhibitors of urokinase-type plasminogen activator and factor Xa.

Verner E, Katz BA, Spencer JR, Allen D, Hataye J, Hruzewicz W, Hui HC, Kolesnikov A, Li Y, Luong C, Martelli A, Radika K, Rai R, She M, Shrader W, Sprengeler PA, Trapp S, Wang J, Young WB, Mackman RL.

J Med Chem. 2001 Aug 16;44(17):2753-71.

PMID:
11495587
3.

Expression, purification, and characterization of deglycosylated human pro-prostate-specific antigen.

Bowman KK, Clark J, Yu L, Mortara K, Radika K, Wang J, Zhan H.

Protein Expr Purif. 2000 Dec;20(3):405-13.

PMID:
11087680
4.

Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator.

Katz BA, Mackman R, Luong C, Radika K, Martelli A, Sprengeler PA, Wang J, Chan H, Wong L.

Chem Biol. 2000 Apr;7(4):299-312.

5.

UDP-N-acetylglucosamine acyltransferase of Escherichia coli. The first step of endotoxin biosynthesis is thermodynamically unfavorable.

Anderson MS, Bull HG, Galloway SM, Kelly TM, Mohan S, Radika K, Raetz CR.

J Biol Chem. 1993 Sep 15;268(26):19858-65.

6.

Anti-immune complex antibodies enhance affinity and specificity of primary antibodies.

Ullman EF, Milburn G, Jelesko J, Radika K, Pirio M, Kempe T, Skold C.

Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1184-9.

7.

Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine.

Loosmore SM, Zealey GR, Boux HA, Cockle SA, Radika K, Fahim RE, Zobrist GJ, Yacoob RK, Chong PC, Yao FL, et al.

Infect Immun. 1990 Nov;58(11):3653-62.

8.

Detoxification of pertussis toxin by site-directed mutagenesis.

Cockle S, Loosmore S, Radika K, Zealey G, Boux H, Phillips K, Klein M.

Adv Exp Med Biol. 1989;251:209-14. No abstract available.

PMID:
2481961
9.

Purification and properties of lipid A disaccharide synthase of Escherichia coli.

Radika K, Raetz CR.

J Biol Chem. 1988 Oct 15;263(29):14859-67.

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13.

A new kinetic diagnostic for enzymatic mechanisms using alternative substrates.

Radika K, Northrop D.

Anal Biochem. 1984 Sep;141(2):413-7.

PMID:
6496948
14.

Purification of two forms of kanamycin acetyltransferase from Escherichia coli.

Radika K, Northrop DB.

Arch Biochem Biophys. 1984 Aug 15;233(1):272-85.

PMID:
6380414
15.

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