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Items: 1 to 50 of 62


Cardiomyocyte orientation modulated by the Numb family proteins-N-cadherin axis is essential for ventricular wall morphogenesis.

Miao L, Li J, Li J, Lu Y, Shieh D, Mazurkiewicz JE, Barroso M, Schwarz JJ, Xin HB, Singer HA, Vincent PA, Zhong W, Radice GL, Wan LQ, Fan ZC, Huang G, Wu M.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15560-15569. doi: 10.1073/pnas.1904684116. Epub 2019 Jul 12.


α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart.

Vite A, Zhang C, Yi R, Emms S, Radice GL.

Development. 2018 Mar 8;145(5). pii: dev149823. doi: 10.1242/dev.149823.


Niche Cadherins Control the Quiescence-to-Activation Transition in Muscle Stem Cells.

Goel AJ, Rieder MK, Arnold HH, Radice GL, Krauss RS.

Cell Rep. 2017 Nov 21;21(8):2236-2250. doi: 10.1016/j.celrep.2017.10.102.


N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis.

Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS.

Dev Biol. 2017 Aug 1;428(1):118-134. doi: 10.1016/j.ydbio.2017.05.022. Epub 2017 May 26.


N-cadherin functions as a growth suppressor in a model of K-ras-induced PanIN.

Su Y, Li J, Shi C, Hruban RH, Radice GL.

Oncogene. 2016 Jun 23;35(25):3335-41. doi: 10.1038/onc.2015.382. Epub 2015 Oct 19.


N-Cadherin Induction by ECM Stiffness and FAK Overrides the Spreading Requirement for Proliferation of Vascular Smooth Muscle Cells.

Mui KL, Bae YH, Gao L, Liu SL, Xu T, Radice GL, Chen CS, Assoian RK.

Cell Rep. 2015 Mar 10;10(9):1477-1486. doi: 10.1016/j.celrep.2015.02.023. Epub 2015 Mar 5.


New functions for alpha-catenins in health and disease: from cancer to heart regeneration.

Vite A, Li J, Radice GL.

Cell Tissue Res. 2015 Jun;360(3):773-83. doi: 10.1007/s00441-015-2123-x. Epub 2015 Feb 12. Review.


Alpha-catenins control cardiomyocyte proliferation by regulating Yap activity.

Li J, Gao E, Vite A, Yi R, Gomez L, Goossens S, van Roy F, Radice GL.

Circ Res. 2015 Jan 2;116(1):70-9. doi: 10.1161/CIRCRESAHA.116.304472. Epub 2014 Oct 10.


N-cadherin/catenin complex as a master regulator of intercalated disc function.

Vite A, Radice GL.

Cell Commun Adhes. 2014 Jun;21(3):169-79. doi: 10.3109/15419061.2014.908853. Epub 2014 Apr 28. Review. Erratum in: Cell Commun Adhes. 2014 Dec;21(6):291.


N-cadherin-mediated adhesion and signaling from development to disease: lessons from mice.

Radice GL.

Prog Mol Biol Transl Sci. 2013;116:263-89. doi: 10.1016/B978-0-12-394311-8.00012-1. Review.


Beyond cell adhesion: the role of armadillo proteins in the heart.

Swope D, Li J, Radice GL.

Cell Signal. 2013 Jan;25(1):93-100. doi: 10.1016/j.cellsig.2012.09.025. Epub 2012 Sep 27. Review.


Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability.

Swope D, Li J, Muller EJ, Radice GL.

Genesis. 2012 Oct;50(10):717-27. doi: 10.1002/dvg.22034. Epub 2012 May 14.


Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia.

Li J, Goossens S, van Hengel J, Gao E, Cheng L, Tyberghein K, Shang X, De Rycke R, van Roy F, Radice GL.

J Cell Sci. 2012 Feb 15;125(Pt 4):1058-67. doi: 10.1242/jcs.098640. Epub 2012 Mar 15.


N-cadherin and β1-integrins cooperate during the development of the enteric nervous system.

Broders-Bondon F, Paul-Gilloteaux P, Carlier C, Radice GL, Dufour S.

Dev Biol. 2012 Apr 15;364(2):178-91. doi: 10.1016/j.ydbio.2012.02.001. Epub 2012 Feb 10.


Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis.

Swope D, Cheng L, Gao E, Li J, Radice GL.

Mol Cell Biol. 2012 Mar;32(6):1056-67. doi: 10.1128/MCB.06188-11. Epub 2012 Jan 17.


N-cadherin haploinsufficiency increases survival in a mouse model of pancreatic cancer.

Su Y, Li J, Witkiewicz AK, Brennan D, Neill T, Talarico J, Radice GL.

Oncogene. 2012 Oct 11;31(41):4484-9. doi: 10.1038/onc.2011.574. Epub 2011 Dec 12.


Requirement for N-cadherin-catenin complex in heart development.

Piven OO, Kostetskii IE, Macewicz LL, Kolomiets YM, Radice GL, Lukash LL.

Exp Biol Med (Maywood). 2011 Jul;236(7):816-22. doi: 10.1258/ebm.2011.010362. Epub 2011 Jun 16.


Cortactin is required for N-cadherin regulation of Kv1.5 channel function.

Cheng L, Yung A, Covarrubias M, Radice GL.

J Biol Chem. 2011 Jun 10;286(23):20478-89. doi: 10.1074/jbc.M111.218560. Epub 2011 Apr 20.


Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling.

Li J, Swope D, Raess N, Cheng L, Muller EJ, Radice GL.

Mol Cell Biol. 2011 Mar;31(6):1134-44. doi: 10.1128/MCB.01025-10. Epub 2011 Jan 18.


Persistence of coordinated long-term potentiation and dendritic spine enlargement at mature hippocampal CA1 synapses requires N-cadherin.

Bozdagi O, Wang XB, Nikitczuk JS, Anderson TR, Bloss EB, Radice GL, Zhou Q, Benson DL, Huntley GW.

J Neurosci. 2010 Jul 28;30(30):9984-9. doi: 10.1523/JNEUROSCI.1223-10.2010.


N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms.

Di Benedetto A, Watkins M, Grimston S, Salazar V, Donsante C, Mbalaviele G, Radice GL, Civitelli R.

J Cell Sci. 2010 Aug 1;123(Pt 15):2640-8. doi: 10.1242/jcs.067777. Epub 2010 Jul 6.


A new perspective on intercalated disc organization: implications for heart disease.

Li J, Radice GL.

Dermatol Res Pract. 2010;2010:207835. doi: 10.1155/2010/207835. Epub 2010 May 5.


N-cadherin is dispensable for pancreas development but required for beta-cell granule turnover.

Johansson JK, Voss U, Kesavan G, Kostetskii I, Wierup N, Radice GL, Semb H.

Genesis. 2010 Jun;48(6):374-81. doi: 10.1002/dvg.20628.


Effects of cardiac-restricted overexpression of the A(2A) adenosine receptor on adriamycin-induced cardiotoxicity.

Hamad EA, Li X, Song J, Zhang XQ, Myers V, Funakoshi H, Zhang J, Wang J, Li J, Swope D, Madonick A, Farber J, Radice GL, Cheung JY, Chan TO, Feldman AM.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H1738-47. doi: 10.1152/ajpheart.00688.2009. Epub 2010 Apr 2.


Adhesive and signaling functions of cadherins and catenins in vertebrate development.

Stepniak E, Radice GL, Vasioukhin V.

Cold Spring Harb Perspect Biol. 2009 Nov;1(5):a002949. doi: 10.1101/cshperspect.a002949. Review.


Hematopoietic stem cells do not depend on N-cadherin to regulate their maintenance.

Kiel MJ, Acar M, Radice GL, Morrison SJ.

Cell Stem Cell. 2009 Feb 6;4(2):170-9. doi: 10.1016/j.stem.2008.10.005.


Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival.

Pontoriero GF, Smith AN, Miller LA, Radice GL, West-Mays JA, Lang RA.

Dev Biol. 2009 Feb 15;326(2):403-17. doi: 10.1016/j.ydbio.2008.10.011. Epub 2008 Nov 1.


The promoter of the oocyte-specific gene, Gdf9, is active in population of cultured mouse embryonic stem cells with an oocyte-like phenotype.

Salvador LM, Silva CP, Kostetskii I, Radice GL, Strauss JF 3rd.

Methods. 2008 Jun;45(2):172-81. doi: 10.1016/j.ymeth.2008.03.004. Epub 2008 May 29.


N-cadherin expression level distinguishes reserved versus primed states of hematopoietic stem cells.

Haug JS, He XC, Grindley JC, Wunderlich JP, Gaudenz K, Ross JT, Paulson A, Wagner KP, Xie Y, Zhu R, Yin T, Perry JM, Hembree MJ, Redenbaugh EP, Radice GL, Seidel C, Li L.

Cell Stem Cell. 2008 Apr 10;2(4):367-79. doi: 10.1016/j.stem.2008.01.017.


Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance.

Kiel MJ, Radice GL, Morrison SJ.

Cell Stem Cell. 2007 Aug 16;1(2):204-17. doi: 10.1016/j.stem.2007.06.001.


N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility.

Li J, Levin MD, Xiong Y, Petrenko N, Patel VV, Radice GL.

J Mol Cell Cardiol. 2008 Mar;44(3):597-606. doi: 10.1016/j.yjmcc.2007.11.013. Epub 2007 Dec 7.


N-cadherin mediates cortical organization in the mouse brain.

Kadowaki M, Nakamura S, Machon O, Krauss S, Radice GL, Takeichi M.

Dev Biol. 2007 Apr 1;304(1):22-33. Epub 2006 Dec 9.


N-cadherin is required for neural crest remodeling of the cardiac outflow tract.

Luo Y, High FA, Epstein JA, Radice GL.

Dev Biol. 2006 Nov 15;299(2):517-28. Epub 2006 Sep 9.


Accentuated ovariectomy-induced bone loss and altered osteogenesis in heterozygous N-cadherin null mice.

Lai CF, Cheng SL, Mbalaviele G, Donsante C, Watkins M, Radice GL, Civitelli R.

J Bone Miner Res. 2006 Dec;21(12):1897-906.


Dysregulation of cell adhesion proteins and cardiac arrhythmogenesis.

Li J, Patel VV, Radice GL.

Clin Med Res. 2006 Mar;4(1):42-52. Review.


Deficiency of SPAG16L causes male infertility associated with impaired sperm motility.

Zhang Z, Kostetskii I, Tang W, Haig-Ladewig L, Sapiro R, Wei Z, Patel AM, Bennett J, Gerton GL, Moss SB, Radice GL, Strauss JF 3rd.

Biol Reprod. 2006 Apr;74(4):751-9. Epub 2005 Dec 28.


Cardiac-specific loss of N-cadherin leads to alteration in connexins with conduction slowing and arrhythmogenesis.

Li J, Patel VV, Kostetskii I, Xiong Y, Chu AF, Jacobson JT, Yu C, Morley GE, Molkentin JD, Radice GL.

Circ Res. 2005 Sep 2;97(5):474-81. Epub 2005 Aug 11.


N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis.

Luo Y, Radice GL.

J Cell Biol. 2005 Apr 11;169(1):29-34. Epub 2005 Apr 4.


Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme.

Edsbagge J, Johansson JK, Esni F, Luo Y, Radice GL, Semb H.

Development. 2005 Mar;132(5):1085-92. Epub 2005 Feb 2.


Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure.

Kostetskii I, Li J, Xiong Y, Zhou R, Ferrari VA, Patel VV, Molkentin JD, Radice GL.

Circ Res. 2005 Feb 18;96(3):346-54. Epub 2005 Jan 20.


N-cadherin is not essential for limb mesenchymal chondrogenesis.

Luo Y, Kostetskii I, Radice GL.

Dev Dyn. 2005 Feb;232(2):336-44.


Haploinsufficiency for the murine orthologue of Chlamydomonas PF20 disrupts spermatogenesis.

Zhang Z, Kostetskii I, Moss SB, Jones BH, Ho C, Wang H, Kishida T, Gerton GL, Radice GL, Strauss JF 3rd.

Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):12946-51. Epub 2004 Aug 24.


Targeted mutation of the MLN64 START domain causes only modest alterations in cellular sterol metabolism.

Kishida T, Kostetskii I, Zhang Z, Martinez F, Liu P, Walkley SU, Dwyer NK, Blanchette-Mackie EJ, Radice GL, Strauss JF 3rd.

J Biol Chem. 2004 Apr 30;279(18):19276-85. Epub 2004 Feb 12.


Inappropriate P-cadherin expression in the mouse mammary epithelium is compatible with normal mammary gland function.

Radice GL, Sauer CL, Kostetskii I, Peralta Soler A, Knudsen KA.

Differentiation. 2003 Aug;71(6):361-73.


Male infertility, impaired sperm motility, and hydrocephalus in mice deficient in sperm-associated antigen 6.

Sapiro R, Kostetskii I, Olds-Clarke P, Gerton GL, Radice GL, Strauss III JF.

Mol Cell Biol. 2002 Sep;22(17):6298-305.


N-cadherin and Cx43alpha1 gap junctions modulates mouse neural crest cell motility via distinct pathways.

Xu X, Li WE, Huang GY, Meyer R, Chen T, Luo Y, Thomas MP, Radice GL, Lo CW.

Cell Commun Adhes. 2001;8(4-6):321-4.


Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart.

Ferreira-Cornwell MC, Luo Y, Narula N, Lenox JM, Lieberman M, Radice GL.

J Cell Sci. 2002 Apr 15;115(Pt 8):1623-34.


Genetic dissection of cadherin function during nephrogenesis.

Dahl U, Sjödin A, Larue L, Radice GL, Cajander S, Takeichi M, Kemler R, Semb H.

Mol Cell Biol. 2002 Mar;22(5):1474-87.

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