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Items: 1 to 50 of 755

1.

A genome-first approach to aggregating rare genetic variants in LMNA for association with electronic health record phenotypes.

Park J, Levin MG, Haggerty CM, Hartzel DN, Judy R, Kember RL, Reza N; Regeneron Genetics Center, Ritchie MD, Owens AT, Damrauer SM, Rader DJ.

Genet Med. 2019 Aug 6. doi: 10.1038/s41436-019-0625-8. [Epub ahead of print]

PMID:
31383942
2.

Polygenic Risk Scores in Familial Hypercholesterolemia.

Rader DJ, Sheth S.

J Am Coll Cardiol. 2019 Jul 30;74(4):523-525. doi: 10.1016/j.jacc.2019.06.006. No abstract available.

PMID:
31345426
3.

Association of APOL1 Risk Alleles with Cardiovascular Disease in African Americans in the Million Veteran Program.

Bick AG, Akwo E, Robinson-Cohen C, Lee K, Lynch J, Assimes TL, DuVall S, Edwards T, Fang H, Freiberg SM, Giri A, Huffman JE, Huang J, Hull L, Kember RL, Klarin D, Lee JS, Levin M, Miller DR, Natarajan P, Saleheen D, Shao Q, Sun YV, Tang H, Wilson O, Chang KM, Cho K, Concato J, Gaziano JM, Kathiresan S, O'Donnell CJ, Rader DJ, Tsao PS, Wilson PW, Hung AM, Damrauer SM; VA Million Veteran Program.

Circulation. 2019 Jul 24. doi: 10.1161/CIRCULATIONAHA.118.036589. [Epub ahead of print]

PMID:
31337231
4.

Effect of Access to Prescribed PCSK9 Inhibitors on Cardiovascular Outcomes.

Myers KD, Farboodi N, Mwamburi M, Howard W, Staszak D, Gidding S, Baum SJ, Wilemon K, Rader DJ.

Circ Cardiovasc Qual Outcomes. 2019 Aug;12(8):e005404. doi: 10.1161/CIRCOUTCOMES.118.005404. Epub 2019 Jul 23.

PMID:
31331194
5.

Finding missed cases of familial hypercholesterolemia in health systems using machine learning.

Banda JM, Sarraju A, Abbasi F, Parizo J, Pariani M, Ison H, Briskin E, Wand H, Dubois S, Jung K, Myers SA, Rader DJ, Leader JB, Murray MF, Myers KD, Wilemon K, Shah NH, Knowles JW.

NPJ Digit Med. 2019 Apr 11;2:23. doi: 10.1038/s41746-019-0101-5. eCollection 2019.

6.

Genome-wide association study of peripheral artery disease in the Million Veteran Program.

Klarin D, Lynch J, Aragam K, Chaffin M, Assimes TL, Huang J, Lee KM, Shao Q, Huffman JE, Natarajan P, Arya S, Small A, Sun YV, Vujkovic M, Freiberg MS, Wang L, Chen J, Saleheen D, Lee JS, Miller DR, Reaven P, Alba PR, Patterson OV, DuVall SL, Boden WE, Beckman JA, Gaziano JM, Concato J, Rader DJ, Cho K, Chang KM, Wilson PWF, O'Donnell CJ, Kathiresan S; VA Million Veteran Program, Tsao PS, Damrauer SM.

Nat Med. 2019 Aug;25(8):1274-1279. doi: 10.1038/s41591-019-0492-5. Epub 2019 Jul 8.

PMID:
31285632
7.

Genomics-First Evaluation of Heart Disease Associated With Titin-Truncating Variants.

Haggerty CM, Damrauer SM, Levin MG, Birtwell D, Carey DJ, Golden AM, Hartzel DN, Hu Y, Judy R, Kelly MA, Kember RL, Lester Kirchner H, Leader JB, Liang L, McDermott-Roe C, Babu A, Morley M, Nealy Z, Person TN, Pulenthiran A, Small A, Smelser DT, Stahl RC, Sturm AC, Williams H, Baras A, Margulies KB, Cappola TP, Dewey FE, Verma A, Zhang X, Correa A, Hall ME, Wilson JG, Ritchie MD, Rader DJ, Murray MF, Fornwalt BK, Arany Z.

Circulation. 2019 Jul 2;140(1):42-54. doi: 10.1161/CIRCULATIONAHA.119.039573. Epub 2019 Jun 20.

PMID:
31216868
8.

FBN1 Coding Variants and Nonsyndromic Aortic Disease.

Damrauer SM, Hardie K, Kember RL, Judy R, Birtwell D, Williams H, Rader DJ, Pyeritz RE.

Circ Genom Precis Med. 2019 Jun;12(6):e002454. doi: 10.1161/CIRCGEN.119.002454. Epub 2019 Jun 18. No abstract available.

PMID:
31211626
9.

Genetic and Epigenetic Fine Mapping of Complex Trait Associated Loci in the Human Liver.

Çalışkan M, Manduchi E, Rao HS, Segert JA, Beltrame MH, Trizzino M, Park Y, Baker SW, Chesi A, Johnson ME, Hodge KM, Leonard ME, Loza B, Xin D, Berrido AM, Hand NJ, Bauer RC, Wells AD, Olthoff KM, Shaked A, Rader DJ, Grant SFA, Brown CD.

Am J Hum Genet. 2019 Jul 3;105(1):89-107. doi: 10.1016/j.ajhg.2019.05.010. Epub 2019 Jun 13.

10.

Association of serum androgens and coronary artery calcium scores in women.

Penn CA, Chan J, Mesaros C, Snyder NW, Rader DJ, Sammel MD, Dokras A.

Fertil Steril. 2019 Jun 11. pii: S0015-0282(19)30402-9. doi: 10.1016/j.fertnstert.2019.04.024. [Epub ahead of print]

PMID:
31200968
11.

Efficacy and Safety of Alirocumab 300 mg Every 4 Weeks in Individuals with Type 2 Diabetes on Maximally Tolerated Statin.

Müller-Wieland D, Rader DJ, Moriarty PM, Bergeron J, Langslet G, Ray KK, Manvelian G, Thompson D, Bujas-Bobanovic M, Roth EM.

J Clin Endocrinol Metab. 2019 Jun 5. pii: jc.2018-02703. doi: 10.1210/jc.2018-02703. [Epub ahead of print]

PMID:
31166599
12.

N-Glycosylation Defects in Humans Lower Low-Density Lipoprotein Cholesterol Through Increased Low-Density Lipoprotein Receptor Expression.

van den Boogert MAW, Larsen LE, Ali L, Kuil SD, Chong PLW, Loregger A, Kroon J, Schnitzler JG, Schimmel AWM, Peter J, Levels JHM, Steenbergen G, Morava E, Dallinga-Thie GM, Wevers RA, Kuivenhoven JA, Hand NJ, Zelcer N, Rader DJ, Stroes ESG, Lefeber DJ, Holleboom AG.

Circulation. 2019 Jul 23;140(4):280-292. doi: 10.1161/CIRCULATIONAHA.118.036484. Epub 2019 May 23.

PMID:
31117816
13.

Effects of Genetic Variants Associated with Familial Hypercholesterolemia on Low-Density Lipoprotein-Cholesterol Levels and Cardiovascular Outcomes in the Million Veteran Program.

Sun YV, Damrauer SM, Hui Q, Assimes TL, Ho YL, Natarajan P, Klarin D, Huang J, Lynch J, DuVall SL, Pyarajan S, Honerlaw JP, Gaziano JM, Cho K, Rader DJ, O'Donnell CJ, Tsao PS, Wilson PWF.

Circ Genom Precis Med. 2018 Dec;11(12). pii: e002192. doi: 10.1161/CIRCGEN.118.002192.

PMID:
31106297
14.

Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

Kranzler HR, Zhou H, Kember RL, Smith RV, Justice AC, Damrauer S, Tsao PS, Klarin D, Baras A, Reid J, Overton J, Rader DJ, Cheng Z, Tate JP, Becker WC, Concato J, Xu K, Polimanti R, Zhao H, Gelernter J.

Nat Commun. 2019 May 17;10(1):2275. doi: 10.1038/s41467-019-10254-5.

15.

Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.

Kranzler HR, Zhou H, Kember RL, Vickers Smith R, Justice AC, Damrauer S, Tsao PS, Klarin D, Baras A, Reid J, Overton J, Rader DJ, Cheng Z, Tate JP, Becker WC, Concato J, Xu K, Polimanti R, Zhao H, Gelernter J.

Nat Commun. 2019 Apr 2;10(1):1499. doi: 10.1038/s41467-019-09480-8. Erratum in: Nat Commun. 2019 May 17;10(1):2275.

16.

Soluble FMS-Like Tyrosine Kinase-1 Is a Circulating Biomarker Associated With Calcific Aortic Stenosis.

Small AM, Kiss DH, Anwaruddin S, Giri J, Han Y, Zhao L, Salvador L, Cvijic ME, Li Z, Chirinos JA, Damrauer SM, Rader DJ.

J Am Coll Cardiol. 2019 Mar 26;73(11):1364-1365. doi: 10.1016/j.jacc.2019.01.020. No abstract available.

PMID:
30898214
17.

Differential network enrichment analysis reveals novel lipid pathways in chronic kidney disease.

Ma J, Karnovsky A, Afshinnia F, Wigginton J, Rader DJ, Natarajan L, Sharma K, Porter AC, Rahman M, He J, Hamm L, Shafi T, Gipson D, Gadegbeku C, Feldman H, Michailidis G, Pennathur S.

Bioinformatics. 2019 Feb 14. pii: btz114. doi: 10.1093/bioinformatics/btz114. [Epub ahead of print]

PMID:
30887029
18.

CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease.

Döring Y, van der Vorst EPC, Duchene J, Jansen Y, Gencer S, Bidzhekov K, Atzler D, Santovito D, Rader DJ, Saleheen D, Weber C.

Circulation. 2019 Mar 5;139(10):1338-1340. doi: 10.1161/CIRCULATIONAHA.118.037953. No abstract available.

PMID:
30865486
19.

Insulin resistance and chronic kidney disease progression, cardiovascular events, and death: findings from the chronic renal insufficiency cohort study.

Schrauben SJ, Jepson C, Hsu JY, Wilson FP, Zhang X, Lash JP, Robinson BM, Townsend RR, Chen J, Fogelfeld L, Kao P, Landis JR, Rader DJ, Hamm LL, Anderson AH, Feldman HI.

BMC Nephrol. 2019 Feb 20;20(1):60. doi: 10.1186/s12882-019-1220-6.

20.

Lipids, Apolipoproteins, and Risk of Atherosclerotic Cardiovascular Disease in Persons With CKD.

Bajaj A, Xie D, Cedillo-Couvert E, Charleston J, Chen J, Deo R, Feldman HI, Go AS, He J, Horwitz E, Kallem R, Rahman M, Weir MR, Anderson AH, Rader DJ; CRIC Study Investigators.

Am J Kidney Dis. 2019 Jun;73(6):827-836. doi: 10.1053/j.ajkd.2018.11.010. Epub 2019 Jan 25.

21.

Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors.

AlDubayan SH, Pyle LC, Gamulin M, Kulis T, Moore ND, Taylor-Weiner A, Hamid AA, Reardon B, Wubbenhorst B, Godse R, Vaughn DJ, Jacobs LA, Meien S, Grgic M, Kastelan Z, Markt SC, Damrauer SM, Rader DJ, Kember RL, Loud JT, Kanetsky PA, Greene MH, Sweeney CJ, Kubisch C, Nathanson KL, Van Allen EM, Stewart DR, Lessel D; Regeneron Genetics Center (RGC) Research Team.

JAMA Oncol. 2019 Apr 1;5(4):514-522. doi: 10.1001/jamaoncol.2018.6477.

PMID:
30676620
22.

Associations between cardiovascular disease, cancer, and very low high-density lipoprotein cholesterol in the REasons for Geographical and Racial Differences in Stroke (REGARDS) study.

Penson P, Long DL, Howard G, Howard VJ, Jones SR, Martin SS, Mikhailidis DP, Muntner P, Rizzo M, Rader DJ, Safford MM, Sahebkar A, Toth PP, Banach M.

Cardiovasc Res. 2019 Jan 1;115(1):204-212. doi: 10.1093/cvr/cvy198.

PMID:
30576432
23.

Genomic Risk Stratification Predicts All-Cause Mortality After Cardiac Catheterization.

Levin MG, Kember RL, Judy R, Birtwell D, Williams H, Arany Z, Giri J, Guerraty M, Cappola T; Regeneron Genetics Center, Chen J, Rader DJ, Damrauer SM.

Circ Genom Precis Med. 2018 Nov;11(11):e002352. doi: 10.1161/CIRCGEN.118.002352.

PMID:
30571185
24.

Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics.

Khoshnejad M, Patel A, Wojtak K, Kudchodkar SB, Humeau L, Lyssenko NN, Rader DJ, Muthumani K, Weiner DB.

Mol Ther. 2019 Jan 2;27(1):188-199. doi: 10.1016/j.ymthe.2018.10.016. Epub 2018 Nov 15.

PMID:
30449662
25.

Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin.

Tuteja S, Qu L, Vujkovic M, Dunbar RL, Chen J, DerOhannessian S, Rader DJ.

J Am Heart Assoc. 2018 Oct 2;7(19):e03488. doi: 10.1161/JAHA.117.008461.

26.

SLCO1B1 and Statin Therapy.

Tuteja S, Rader DJ.

Circ Genom Precis Med. 2018 Sep;11(9):e002320. doi: 10.1161/CIRCGEN.118.002320. No abstract available.

PMID:
30354338
27.

Reporting Sex and Sex Differences in Preclinical Studies.

Lu HS, Schmidt AM, Hegele RA, Mackman N, Rader DJ, Weber C, Daugherty A.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):e171-e184. doi: 10.1161/ATVBAHA.118.311717. No abstract available.

PMID:
30354222
28.

ATP binding cassette family A protein 1 determines hexosylceramide and sphingomyelin levels in human and mouse plasma.

Iqbal J, Walsh MT, Hammad SM, Cuchel M, Rader DJ, Hussain MM.

J Lipid Res. 2018 Nov;59(11):2084-2097. doi: 10.1194/jlr.M087502. Epub 2018 Oct 2.

PMID:
30279221
29.

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

Klarin D, Damrauer SM, Cho K, Sun YV, Teslovich TM, Honerlaw J, Gagnon DR, DuVall SL, Li J, Peloso GM, Chaffin M, Small AM, Huang J, Tang H, Lynch JA, Ho YL, Liu DJ, Emdin CA, Li AH, Huffman JE, Lee JS, Natarajan P, Chowdhury R, Saleheen D, Vujkovic M, Baras A, Pyarajan S, Di Angelantonio E, Neale BM, Naheed A, Khera AV, Danesh J, Chang KM, Abecasis G, Willer C, Dewey FE, Carey DJ; Global Lipids Genetics Consortium; Myocardial Infarction Genetics (MIGen) Consortium; Geisinger-Regeneron DiscovEHR Collaboration; VA Million Veteran Program, Concato J, Gaziano JM, O'Donnell CJ, Tsao PS, Kathiresan S, Rader DJ, Wilson PWF, Assimes TL.

Nat Genet. 2018 Nov;50(11):1514-1523. doi: 10.1038/s41588-018-0222-9. Epub 2018 Oct 1.

30.

Genetic Regulatory Mechanisms of Smooth Muscle Cells Map to Coronary Artery Disease Risk Loci.

Liu B, Pjanic M, Wang T, Nguyen T, Gloudemans M, Rao A, Castano VG, Nurnberg S, Rader DJ, Elwyn S, Ingelsson E, Montgomery SB, Miller CL, Quertermous T.

Am J Hum Genet. 2018 Sep 6;103(3):377-388. doi: 10.1016/j.ajhg.2018.08.001. Epub 2018 Aug 23.

31.

The future of humans as model organisms.

FitzGerald G, Botstein D, Califf R, Collins R, Peters K, Van Bruggen N, Rader D.

Science. 2018 Aug 10;361(6402):552-553. doi: 10.1126/science.aau7779. No abstract available.

PMID:
30093589
32.

Directional ABCA1-mediated cholesterol efflux and apoB-lipoprotein secretion in the retinal pigment epithelium.

Lyssenko NN, Haider N, Picataggi A, Cipollari E, Jiao W, Phillips MC, Rader DJ, Chavali VRM.

J Lipid Res. 2018 Oct;59(10):1927-1939. doi: 10.1194/jlr.M087361. Epub 2018 Aug 3.

PMID:
30076206
33.

Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel.

Sturm AC, Knowles JW, Gidding SS, Ahmad ZS, Ahmed CD, Ballantyne CM, Baum SJ, Bourbon M, Carrié A, Cuchel M, de Ferranti SD, Defesche JC, Freiberger T, Hershberger RE, Hovingh GK, Karayan L, Kastelein JJP, Kindt I, Lane SR, Leigh SE, Linton MF, Mata P, Neal WA, Nordestgaard BG, Santos RD, Harada-Shiba M, Sijbrands EJ, Stitziel NO, Yamashita S, Wilemon KA, Ledbetter DH, Rader DJ; Convened by the Familial Hypercholesterolemia Foundation.

J Am Coll Cardiol. 2018 Aug 7;72(6):662-680. doi: 10.1016/j.jacc.2018.05.044. Review.

34.

Apolipoprotein A-I Infusion Therapies for Coronary Disease: Two Outs in the Ninth Inning and Swinging for the Fences.

Rader DJ.

JAMA Cardiol. 2018 Sep 1;3(9):799-801. doi: 10.1001/jamacardio.2018.2168. No abstract available.

PMID:
30046821
35.

Multiplexed Targeted Resequencing Identifies Coding and Regulatory Variation Underlying Phenotypic Extremes of High-Density Lipoprotein Cholesterol in Humans.

Khetarpal SA, Babb PL, Zhao W, Hancock-Cerutti WF, Brown CD, Rader DJ, Voight BF.

Circ Genom Precis Med. 2018 Jul;11(7):e002070. doi: 10.1161/CIRCGEN.117.002070.

36.

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.

Gusarova V, O'Dushlaine C, Teslovich TM, Benotti PN, Mirshahi T, Gottesman O, Van Hout CV, Murray MF, Mahajan A, Nielsen JB, Fritsche L, Wulff AB, Gudbjartsson DF, Sjögren M, Emdin CA, Scott RA, Lee WJ, Small A, Kwee LC, Dwivedi OP, Prasad RB, Bruse S, Lopez AE, Penn J, Marcketta A, Leader JB, Still CD, Kirchner HL, Mirshahi UL, Wardeh AH, Hartle CM, Habegger L, Fetterolf SN, Tusie-Luna T, Morris AP, Holm H, Steinthorsdottir V, Sulem P, Thorsteinsdottir U, Rotter JI, Chuang LM, Damrauer S, Birtwell D, Brummett CM, Khera AV, Natarajan P, Orho-Melander M, Flannick J, Lotta LA, Willer CJ, Holmen OL, Ritchie MD, Ledbetter DH, Murphy AJ, Borecki IB, Reid JG, Overton JD, Hansson O, Groop L, Shah SH, Kraus WE, Rader DJ, Chen YI, Hveem K, Wareham NJ, Kathiresan S, Melander O, Stefansson K, Nordestgaard BG, Tybjærg-Hansen A, Abecasis GR, Altshuler D, Florez JC, Boehnke M, McCarthy MI, Yancopoulos GD, Carey DJ, Shuldiner AR, Baras A, Dewey FE, Gromada J.

Nat Commun. 2018 Jun 13;9(1):2252. doi: 10.1038/s41467-018-04611-z.

37.

Multi-ethnic genome-wide association study for atrial fibrillation.

Roselli C, Chaffin MD, Weng LC, Aeschbacher S, Ahlberg G, Albert CM, Almgren P, Alonso A, Anderson CD, Aragam KG, Arking DE, Barnard J, Bartz TM, Benjamin EJ, Bihlmeyer NA, Bis JC, Bloom HL, Boerwinkle E, Bottinger EB, Brody JA, Calkins H, Campbell A, Cappola TP, Carlquist J, Chasman DI, Chen LY, Chen YI, Choi EK, Choi SH, Christophersen IE, Chung MK, Cole JW, Conen D, Cook J, Crijns HJ, Cutler MJ, Damrauer SM, Daniels BR, Darbar D, Delgado G, Denny JC, Dichgans M, Dörr M, Dudink EA, Dudley SC, Esa N, Esko T, Eskola M, Fatkin D, Felix SB, Ford I, Franco OH, Geelhoed B, Grewal RP, Gudnason V, Guo X, Gupta N, Gustafsson S, Gutmann R, Hamsten A, Harris TB, Hayward C, Heckbert SR, Hernesniemi J, Hocking LJ, Hofman A, Horimoto ARVR, Huang J, Huang PL, Huffman J, Ingelsson E, Ipek EG, Ito K, Jimenez-Conde J, Johnson R, Jukema JW, Kääb S, Kähönen M, Kamatani Y, Kane JP, Kastrati A, Kathiresan S, Katschnig-Winter P, Kavousi M, Kessler T, Kietselaer BL, Kirchhof P, Kleber ME, Knight S, Krieger JE, Kubo M, Launer LJ, Laurikka J, Lehtimäki T, Leineweber K, Lemaitre RN, Li M, Lim HE, Lin HJ, Lin H, Lind L, Lindgren CM, Lokki ML, London B, Loos RJF, Low SK, Lu Y, Lyytikäinen LP, Macfarlane PW, Magnusson PK, Mahajan A, Malik R, Mansur AJ, Marcus GM, Margolin L, Margulies KB, März W, McManus DD, Melander O, Mohanty S, Montgomery JA, Morley MP, Morris AP, Müller-Nurasyid M, Natale A, Nazarian S, Neumann B, Newton-Cheh C, Niemeijer MN, Nikus K, Nilsson P, Noordam R, Oellers H, Olesen MS, Orho-Melander M, Padmanabhan S, Pak HN, Paré G, Pedersen NL, Pera J, Pereira A, Porteous D, Psaty BM, Pulit SL, Pullinger CR, Rader DJ, Refsgaard L, Ribasés M, Ridker PM, Rienstra M, Risch L, Roden DM, Rosand J, Rosenberg MA, Rost N, Rotter JI, Saba S, Sandhu RK, Schnabel RB, Schramm K, Schunkert H, Schurman C, Scott SA, Seppälä I, Shaffer C, Shah S, Shalaby AA, Shim J, Shoemaker MB, Siland JE, Sinisalo J, Sinner MF, Slowik A, Smith AV, Smith BH, Smith JG, Smith JD, Smith NL, Soliman EZ, Sotoodehnia N, Stricker BH, Sun A, Sun H, Svendsen JH, Tanaka T, Tanriverdi K, Taylor KD, Teder-Laving M, Teumer A, Thériault S, Trompet S, Tucker NR, Tveit A, Uitterlinden AG, Van Der Harst P, Van Gelder IC, Van Wagoner DR, Verweij N, Vlachopoulou E, Völker U, Wang B, Weeke PE, Weijs B, Weiss R, Weiss S, Wells QS, Wiggins KL, Wong JA, Woo D, Worrall BB, Yang PS, Yao J, Yoneda ZT, Zeller T, Zeng L, Lubitz SA, Lunetta KL, Ellinor PT.

Nat Genet. 2018 Jun 11;50(9):1225-1233. doi: 10.1038/s41588-018-0133-9.

38.

High density lipoprotein cholesterol and cancer: Marker or causative?

Pirro M, Ricciuti B, Rader DJ, Catapano AL, Sahebkar A, Banach M.

Prog Lipid Res. 2018 Jul;71:54-69. doi: 10.1016/j.plipres.2018.06.001. Epub 2018 Jun 4. Review.

PMID:
29879431
39.

Response by Daugherty et al to Letter Regarding Article, "Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies: A Statement From the Arteriosclerosis, Thrombosis, and Vascular Biology Council".

Daugherty A, Lu HS, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C.

Arterioscler Thromb Vasc Biol. 2018 Jun;38(6):e101-e102. doi: 10.1161/ATVBAHA.118.310988. No abstract available.

PMID:
29793996
40.

Effect of 2 Psoriasis Treatments on Vascular Inflammation and Novel Inflammatory Cardiovascular Biomarkers: A Randomized Placebo-Controlled Trial.

Mehta NN, Shin DB, Joshi AA, Dey AK, Armstrong AW, Duffin KC, Fuxench ZC, Harrington CL, Hubbard RA, Kalb RE, Menter A, Rader DJ, Reilly MP, Simpson EL, Takeshita J, Torigian DA, Werner TJ, Troxel AB, Tyring SK, Vanderbeek SB, Van Voorhees AS, Playford MP, Ahlman MA, Alavi A, Gelfand JM.

Circ Cardiovasc Imaging. 2018 Jun;11(6):e007394. doi: 10.1161/CIRCIMAGING.117.007394.

41.

A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity.

Seckler HDS, Fornelli L, Mutharasan RK, Thaxton CS, Fellers R, Daviglus M, Sniderman A, Rader D, Kelleher NL, Lloyd-Jones DM, Compton PD, Wilkins JT.

J Proteome Res. 2018 Jun 1;17(6):2156-2164. doi: 10.1021/acs.jproteome.8b00100. Epub 2018 Apr 27.

42.

A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease.

Abul-Husn NS, Cheng X, Li AH, Xin Y, Schurmann C, Stevis P, Liu Y, Kozlitina J, Stender S, Wood GC, Stepanchick AN, Still MD, McCarthy S, O'Dushlaine C, Packer JS, Balasubramanian S, Gosalia N, Esopi D, Kim SY, Mukherjee S, Lopez AE, Fuller ED, Penn J, Chu X, Luo JZ, Mirshahi UL, Carey DJ, Still CD, Feldman MD, Small A, Damrauer SM, Rader DJ, Zambrowicz B, Olson W, Murphy AJ, Borecki IB, Shuldiner AR, Reid JG, Overton JD, Yancopoulos GD, Hobbs HH, Cohen JC, Gottesman O, Teslovich TM, Baras A, Mirshahi T, Gromada J, Dewey FE.

N Engl J Med. 2018 Mar 22;378(12):1096-1106. doi: 10.1056/NEJMoa1712191.

43.

Angiopoietin-like protein 4: A therapeutic target for triglycerides and coronary disease?

Olshan DS, Rader DJ.

J Clin Lipidol. 2018 May - Jun;12(3):583-587. doi: 10.1016/j.jacl.2018.01.012. Epub 2018 Feb 2. Review.

PMID:
29548670
44.

Efficacy and safety of lipid lowering by alirocumab in chronic kidney disease.

Toth PP, Dwyer JP, Cannon CP, Colhoun HM, Rader DJ, Upadhyay A, Louie MJ, Koren A, Letierce A, Mandel J, Banach M.

Kidney Int. 2018 Jun;93(6):1397-1408. doi: 10.1016/j.kint.2017.12.011. Epub 2018 Mar 8.

45.

New Therapeutic Approaches for Familial Hypercholesterolemia.

Ajufo E, Rader DJ.

Annu Rev Med. 2018 Jan 29;69:113-131. doi: 10.1146/annurev-med-051215-030943.

PMID:
29414257
46.

Plastic waste associated with disease on coral reefs.

Lamb JB, Willis BL, Fiorenza EA, Couch CS, Howard R, Rader DN, True JD, Kelly LA, Ahmad A, Jompa J, Harvell CD.

Science. 2018 Jan 26;359(6374):460-462. doi: 10.1126/science.aar3320.

PMID:
29371469
47.

Zinc transporter Slc39a8 is essential for cardiac ventricular compaction.

Lin W, Li D, Cheng L, Li L, Liu F, Hand NJ, Epstein JA, Rader DJ.

J Clin Invest. 2018 Feb 1;128(2):826-833. doi: 10.1172/JCI96993. Epub 2018 Jan 16.

48.

Prior Authorization Requirements for Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors Across US Private and Public Payers.

Doshi JA, Puckett JT, Parmacek MS, Rader DJ.

Circ Cardiovasc Qual Outcomes. 2018 Jan;11(1):e003939. doi: 10.1161/CIRCOUTCOMES.117.003939.

PMID:
29326146
49.

NHLBI Working Group Recommendations to Reduce Lipoprotein(a)-Mediated Risk of Cardiovascular Disease and Aortic Stenosis.

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