Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 198

1.

Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates.

Hwang D, Tsuji K, Park H, Burke TR Jr, Rader C.

Bioconjug Chem. 2019 Nov 20;30(11):2889-2896. doi: 10.1021/acs.bioconjchem.9b00609. Epub 2019 Nov 1.

PMID:
31675216
2.

Conventional and Chemically Programmed Asymmetric Bispecific Antibodies Targeting Folate Receptor 1.

Qi J, Hymel D, Nelson CG, Burke TR Jr, Rader C.

Front Immunol. 2019 Aug 21;10:1994. doi: 10.3389/fimmu.2019.01994. eCollection 2019.

3.

Six-packed antibodies punch better.

Rader C, Wiestner A.

Haematologica. 2019 Sep;104(9):1696-1699. doi: 10.3324/haematol.2019.224196. No abstract available.

4.

Engineering Dual Variable Domains for the Generation of Site-Specific Antibody-Drug Conjugates.

Nanna AR, Rader C.

Methods Mol Biol. 2019;2033:39-52. doi: 10.1007/978-1-4939-9654-4_4.

PMID:
31332746
5.

Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues.

Hwang D, Nilchan N, Nanna AR, Li X, Cameron MD, Roush WR, Park H, Rader C.

Cell Chem Biol. 2019 Sep 19;26(9):1229-1239.e9. doi: 10.1016/j.chembiol.2019.05.010. Epub 2019 Jun 20.

PMID:
31231031
6.

ROR1-targeted delivery of miR-29b induces cell cycle arrest and therapeutic benefit in vivo in a CLL mouse model.

Chiang CL, Goswami S, Frissora FW, Xie Z, Yan PS, Bundschuh R, Walker LA, Huang X, Mani R, Mo XM, Baskar S, Rader C, Phelps MA, Marcucci G, Byrd JC, Lee LJ, Muthusamy N.

Blood. 2019 Aug 1;134(5):432-444. doi: 10.1182/blood.2018882290. Epub 2019 May 31.

PMID:
31151986
7.

Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting.

Srivastava S, Salter AI, Liggitt D, Yechan-Gunja S, Sarvothama M, Cooper K, Smythe KS, Dudakov JA, Pierce RH, Rader C, Riddell SR.

Cancer Cell. 2019 Mar 18;35(3):489-503.e8. doi: 10.1016/j.ccell.2019.02.003.

PMID:
30889382
8.

"One, if by land, and two, if by sea": bispecific antibodies join the revolution.

Rader C.

Methods. 2019 Feb 1;154:1-2. doi: 10.1016/j.ymeth.2018.12.004. No abstract available.

PMID:
30683271
9.

Chimeric Antigen Receptor Library Screening Using a Novel NF-κB/NFAT Reporter Cell Platform.

Rydzek J, Nerreter T, Peng H, Jutz S, Leitner J, Steinberger P, Einsele H, Rader C, Hudecek M.

Mol Ther. 2019 Feb 6;27(2):287-299. doi: 10.1016/j.ymthe.2018.11.015. Epub 2018 Nov 20.

PMID:
30573301
10.

CAR T cells targeting αvβ3 integrin are effective against advanced cancer in preclinical models.

Wallstabe L, Mades A, Frenz S, Einsele H, Rader C, Hudecek M.

Adv Cell Gene Ther. 2018 Sep;1(2). pii: e11. doi: 10.1002/acg2.11. Epub 2018 Jul 10.

11.

Rabbit models of human diseases for diagnostics and therapeutics development.

Mage RG, Esteves PJ, Rader C.

Dev Comp Immunol. 2019 Mar;92:99-104. doi: 10.1016/j.dci.2018.10.003. Epub 2018 Oct 16. Review.

PMID:
30339876
12.

Pain Management in Pectus Excavatum Surgery: A Comparison of Subcutaneous Catheters Versus Epidurals in a Pediatric Population.

Thaker S, McKenna E, Rader C, Misra MV.

J Laparoendosc Adv Surg Tech A. 2019 Feb;29(2):261-266. doi: 10.1089/lap.2018.0244. Epub 2018 Sep 25.

PMID:
30256160
13.

A Sortase A Programmable Phage Display Format for Improved Panning of Fab Antibody Libraries.

Wilson HD, Li X, Peng H, Rader C.

J Mol Biol. 2018 Oct 19;430(21):4387-4400. doi: 10.1016/j.jmb.2018.09.003. Epub 2018 Sep 11.

14.

Comparative Studies of the Biosynthetic Gene Clusters for Anthraquinone-Fused Enediynes Shedding Light into the Tailoring Steps of Tiancimycin Biosynthesis.

Yan X, Chen JJ, Adhikari A, Teijaro CN, Ge H, Crnovcic I, Chang CY, Annaval T, Yang D, Rader C, Shen B.

Org Lett. 2018 Sep 21;20(18):5918-5921. doi: 10.1021/acs.orglett.8b02584. Epub 2018 Sep 13.

15.

An IgG1-like bispecific antibody targeting CD52 and CD20 for the treatment of B-cell malignancies.

Qi J, Chen SS, Chiorazzi N, Rader C.

Methods. 2019 Feb 1;154:70-76. doi: 10.1016/j.ymeth.2018.08.008. Epub 2018 Aug 24.

PMID:
30145356
16.

[Update of the German S3 guideline on atraumatic femoral head necrosis in adults].

Roth A, Beckmann J, Bohndorf K, Heiß C, Jäger M, Landgraeber S, Maus U, Nöth U, Peters KM, Rader C, Reppenhagen S, Smolenski U, Kopp I, Tingart M.

Orthopade. 2018 Sep;47(9):757-769. doi: 10.1007/s00132-018-3620-x. Review. German.

PMID:
30116852
17.

Batter Up.

Knippa S, Rauen CA, Boyd TA, Rader C.

Crit Care Nurse. 2018 Aug;38(4):68-72. doi: 10.4037/ccn2018272. No abstract available.

PMID:
30068722
18.

Siglec-6 on Chronic Lymphocytic Leukemia Cells Is a Target for Post-Allogeneic Hematopoietic Stem Cell Transplantation Antibodies.

Chang J, Peng H, Shaffer BC, Baskar S, Wecken IC, Cyr MG, Martinez GJ, Soden J, Freeth J, Wiestner A, Rader C.

Cancer Immunol Res. 2018 Sep;6(9):1008-1013. doi: 10.1158/2326-6066.CIR-18-0102. Epub 2018 Jul 6.

19.

Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.

Qi J, Li X, Peng H, Cook EM, Dadashian EL, Wiestner A, Park H, Rader C.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5467-E5476. doi: 10.1073/pnas.1719905115. Epub 2018 May 29.

20.

A CD19/CD3 bispecific antibody for effective immunotherapy of chronic lymphocytic leukemia in the ibrutinib era.

Robinson HR, Qi J, Cook EM, Nichols C, Dadashian EL, Underbayev C, Herman SEM, Saba NS, Keyvanfar K, Sun C, Ahn IE, Baskar S, Rader C, Wiestner A.

Blood. 2018 Aug 2;132(5):521-532. doi: 10.1182/blood-2018-02-830992. Epub 2018 May 9.

21.

Pectus Carinatum: Factors That Contribute to Success and Failure of Nonoperative Treatment.

Thaker S, Anderson M, Fezio J, Rader C, Misra MV.

Conn Med. 2017 Apr;81(4):203-208.

PMID:
29714404
22.

Postoperative Pain Outcomes After Nuss Procedures: Comparison of Epidural Analgesia, Continuous Infusion of Local Anesthetic, and Preoperative Self-Hypnosis Training.

Manworren RCB, Anderson MN, Girard ED, Ruscher KA, Verissimo AM, Palac H, Weiss R, Rader C, Hight D.

J Laparoendosc Adv Surg Tech A. 2018 Oct;28(10):1234-1242. doi: 10.1089/lap.2017.0699. Epub 2018 Apr 2.

PMID:
29608431
23.

Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne.

Yan X, Chen JJ, Adhikari A, Yang D, Crnovcic I, Wang N, Chang CY, Rader C, Shen B.

Org Lett. 2017 Nov 17;19(22):6192-6195. doi: 10.1021/acs.orglett.7b03120. Epub 2017 Oct 31.

24.

Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates.

Nanna AR, Li X, Walseng E, Pedzisa L, Goydel RS, Hymel D, Burke TR Jr, Roush WR, Rader C.

Nat Commun. 2017 Oct 24;8(1):1112. doi: 10.1038/s41467-017-01257-1.

25.

Chimeric rabbit/human Fab antibodies against the hepatitis Be-antigen and their potential applications in assays, characterization, and therapy.

Zhuang X, Watts NR, Palmer IW, Kaufman JD, Dearborn AD, Trenbeath JL, Eren E, Steven AC, Rader C, Wingfield PT.

J Biol Chem. 2017 Oct 6;292(40):16760-16772. doi: 10.1074/jbc.M117.802272. Epub 2017 Aug 23.

26.

Mining Naïve Rabbit Antibody Repertoires by Phage Display for Monoclonal Antibodies of Therapeutic Utility.

Peng H, Nerreter T, Chang J, Qi J, Li X, Karunadharma P, Martinez GJ, Fallahi M, Soden J, Freeth J, Beerli RR, Grawunder U, Hudecek M, Rader C.

J Mol Biol. 2017 Sep 15;429(19):2954-2973. doi: 10.1016/j.jmb.2017.08.003. Epub 2017 Aug 14.

27.

From rabbit antibody repertoires to rabbit monoclonal antibodies.

Weber J, Peng H, Rader C.

Exp Mol Med. 2017 Mar 24;49(3):e305. doi: 10.1038/emm.2017.23. Review.

28.

Stable and Potent Selenomab-Drug Conjugates.

Li X, Nelson CG, Nair RR, Hazlehurst L, Moroni T, Martinez-Acedo P, Nanna AR, Hymel D, Burke TR Jr, Rader C.

Cell Chem Biol. 2017 Apr 20;24(4):433-442.e6. doi: 10.1016/j.chembiol.2017.02.012. Epub 2017 Mar 16.

29.

Utilization of Selenocysteine for Site-Specific Antibody Conjugation.

Li X, Rader C.

Methods Mol Biol. 2017;1575:145-164. doi: 10.1007/978-1-4939-6857-2_8.

PMID:
28255878
30.

Mechanically switchable polymer fibers for sensing in biological conditions.

McMillan S, Rader C, Jorfi M, Pickrell G, Foster EJ.

J Biomed Opt. 2017 Feb 1;22(2):27001. doi: 10.1117/1.JBO.22.2.027001.

31.

Strain Prioritization and Genome Mining for Enediyne Natural Products.

Yan X, Ge H, Huang T, Hindra, Yang D, Teng Q, Crnovčić I, Li X, Rudolf JD, Lohman JR, Gansemans Y, Zhu X, Huang Y, Zhao LX, Jiang Y, Van Nieuwerburgh F, Rader C, Duan Y, Shen B.

MBio. 2016 Dec 20;7(6). pii: e02104-16. doi: 10.1128/mBio.02104-16.

32.

Human Serum Albumin Domain I Fusion Protein for Antibody Conjugation.

Patterson JT, Wilson HD, Asano S, Nilchan N, Fuller RP, Roush WR, Rader C, Barbas CF 3rd.

Bioconjug Chem. 2016 Oct 19;27(10):2271-2275. Epub 2016 Sep 26.

33.

Tagging the Untaggable: A Difluoroalkyl-Sulfinate Ketone-Based Reagent for Direct C-H Functionalization of Bioactive Heteroarenes.

Gnaim S, Scomparin A, Li X, Baran PS, Rader C, Satchi-Fainaro R, Shabat D.

Bioconjug Chem. 2016 Sep 21;27(9):1965-71. doi: 10.1021/acs.bioconjchem.6b00382. Epub 2016 Aug 15.

PMID:
27494153
34.

Chemically Programmed Bispecific Antibodies in Diabody Format.

Walseng E, Nelson CG, Qi J, Nanna AR, Roush WR, Goswami RK, Sinha SC, Burke TR Jr, Rader C.

J Biol Chem. 2016 Sep 9;291(37):19661-73. doi: 10.1074/jbc.M116.745588. Epub 2016 Jul 21.

35.

Assessment of reagents for selenocysteine conjugation and the stability of selenocysteine adducts.

Pedzisa L, Li X, Rader C, Roush WR.

Org Biomol Chem. 2016 Jun 14;14(22):5141-7. doi: 10.1039/c6ob00775a. Epub 2016 May 17.

36.

Engineered production of cancer targeting peptide (CTP)-containing C-1027 in Streptomyces globisporus and biological evaluation.

Li W, Li X, Huang T, Teng Q, Crnovcic I, Rader C, Shen B.

Bioorg Med Chem. 2016 Sep 1;24(17):3887-3892. doi: 10.1016/j.bmc.2016.04.017. Epub 2016 Apr 8.

37.

Efficacy of Analgesic Treatments to Manage Children's Postoperative Pain After Laparoscopic Appendectomy: Retrospective Medical Record Review.

Manworren RC, McElligott CD, Deraska PV, Santanelli J, Blair S, Ruscher KA, Weiss R, Rader C, Finck C, Bourque M, Campbell B.

AORN J. 2016 Mar;103(3):317.e1-11. doi: 10.1016/j.aorn.2016.01.013.

PMID:
26924376
38.

Targeting Stereotyped B Cell Receptors from Chronic Lymphocytic Leukemia Patients with Synthetic Antigen Surrogates.

Sarkar M, Liu Y, Qi J, Peng H, Morimoto J, Rader C, Chiorazzi N, Kodadek T.

J Biol Chem. 2016 Apr 1;291(14):7558-70. doi: 10.1074/jbc.M115.701656. Epub 2016 Feb 5.

39.

S3-Guideline non-traumatic adult femoral head necrosis.

Roth A, Beckmann J, Bohndorf K, Fischer A, Heiß C, Kenn W, Jäger M, Maus U, Nöth U, Peters KM, Rader C, Reppenhagen S, Smolenski U, Tingart M, Kopp I, Sirotin I, Breusch SJ.

Arch Orthop Trauma Surg. 2016 Feb;136(2):165-74. doi: 10.1007/s00402-015-2375-7. Epub 2015 Dec 14.

PMID:
26667621
40.

Angucyclines and Angucyclinones from Streptomyces sp. CB01913 Featuring C-Ring Cleavage and Expansion.

Ma M, Rateb ME, Teng Q, Yang D, Rudolf JD, Zhu X, Huang Y, Zhao LX, Jiang Y, Li X, Rader C, Duan Y, Shen B.

J Nat Prod. 2015 Oct 23;78(10):2471-80. doi: 10.1021/acs.jnatprod.5b00601. Epub 2015 Sep 3.

41.

[S3 Guideline. Part 1: Diagnosis and Differential Diagnosis of Non-Traumatic Adult Femoral Head Necrosis].

Bohndorf K, Beckmann J, Jäger M, Kenn W, Maus U, Nöth U, Peters KM, Rader C, Reppenhagen S, Roth A; Deutsche Gesellschaft für Orthopädie und Orthopädische Chirurgie.

Z Orthop Unfall. 2015 Aug;153(4):375-86. doi: 10.1055/s-0035-1545901. Epub 2015 Aug 14. Review. German.

PMID:
26274557
42.

[S3 guideline. Part 2: Non-Traumatic Avascular Femoral Head Necrosis in Adults - Untreated Course and Conservative Treatment].

Roth A, Beckmann J, Smolenski U, Fischer A, Jäger M, Tingart M, Rader C, Peters KM, Reppenhagen S, Nöth U, Heiss C, Maus U.

Z Orthop Unfall. 2015 Oct;153(5):488-97. doi: 10.1055/s-0035-1545903. Epub 2015 Aug 5. German.

PMID:
26244940
43.

[S3 Guideline. Part 3: Non-Traumatic Avascular Necrosis in Adults - Surgical Treatment of Atraumatic Avascular Femoral Head Necrosis in Adults].

Maus U, Roth A, Tingart M, Rader C, Jäger M, Nöth U, Reppenhagen S, Heiss C, Beckmann J.

Z Orthop Unfall. 2015 Oct;153(5):498-507. doi: 10.1055/s-0035-1545902. Epub 2015 Aug 5. German.

PMID:
26244939
44.

[Osteomalacia and vitamin D deficiency].

Rader CP, Corsten N, Rolf O.

Orthopade. 2015 Sep;44(9):695-702. doi: 10.1007/s00132-015-3141-9. German.

PMID:
26205357
45.

IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas.

Huang X, Park H, Greene J, Pao J, Mulvey E, Zhou SX, Albert CM, Moy F, Sachdev D, Yee D, Rader C, Hamby CV, Loeb DM, Cairo MS, Zhou X.

PLoS One. 2015 Jul 14;10(7):e0133152. doi: 10.1371/journal.pone.0133152. eCollection 2015.

46.

Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues.

Li X, Patterson JT, Sarkar M, Pedzisa L, Kodadek T, Roush WR, Rader C.

Bioconjug Chem. 2015 Nov 18;26(11):2243-8. doi: 10.1021/acs.bioconjchem.5b00244. Epub 2015 Jul 24.

47.

Current trends in the surgical treatment of pediatric ovarian torsion: we can do better.

Campbell BT, Austin DM, Kahn O, McCann MC, Lerer TJ, Lee K, Thaker S, Herbst KW, Rader CM.

J Pediatr Surg. 2015 Aug;50(8):1374-7. doi: 10.1016/j.jpedsurg.2015.04.018. Epub 2015 May 9.

PMID:
26026345
48.

ROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo.

Mani R, Chiang CL, Frissora FW, Yan R, Mo X, Baskar S, Rader C, Klisovic R, Phelps MA, Chen CS, Lee RJ, Byrd JC, Baiocchi R, Lee LJ, Muthusamy N.

Exp Hematol. 2015 Sep;43(9):770-4.e2. doi: 10.1016/j.exphem.2015.04.008. Epub 2015 Apr 29.

PMID:
25937048
49.

Lipid-directed vinculin dimerization.

Chinthalapudi K, Patil DN, Rangarajan ES, Rader C, Izard T.

Biochemistry. 2015 May 5;54(17):2758-68. doi: 10.1021/acs.biochem.5b00015. Epub 2015 Apr 24.

PMID:
25880222
50.

Chemical biology: How to minimalize antibodies.

Rader C.

Nature. 2015 Feb 5;518(7537):38-9. doi: 10.1038/518038a. No abstract available.

PMID:
25652990

Supplemental Content

Support Center