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Items: 39


B-cell depletion is ineffective in a patient with granulomatous optic neuropathy.

Wagner F, Radbruch H, Witte OW, Geis C.

Neurol Neuroimmunol Neuroinflamm. 2018 Aug 10;5(5):e493. doi: 10.1212/NXI.0000000000000493. eCollection 2018 Sep. No abstract available.


Drug reaction with eosinophilia and systemic symptoms after daclizumab therapy in MS.

Scheibe F, Metz I, Radbruch H, Siebert E, Wolf S, Köhnlein M, Harms L, Meisel A.

Neurol Neuroimmunol Neuroinflamm. 2018 Jul 10;5(5):e479. doi: 10.1212/NXI.0000000000000479. eCollection 2018 Sep. No abstract available.


Phasor-Based Endogenous NAD(P)H Fluorescence Lifetime Imaging Unravels Specific Enzymatic Activity of Neutrophil Granulocytes Preceding NETosis.

Leben R, Ostendorf L, van Koppen S, Rakhymzhan A, Hauser AE, Radbruch H, Niesner RA.

Int J Mol Sci. 2018 Mar 29;19(4). pii: E1018. doi: 10.3390/ijms19041018.


Neuro-Behcet's disease in a patient with thrombotic thrombocytopenic purpura.

Karaivanov S, Krueger A, Bethke N, Radbruch H, Eckardt KU, Schreiber A.

Rheumatology (Oxford). 2018 Jun 1;57(6):1117-1118. doi: 10.1093/rheumatology/kex533. No abstract available.


Necrosis in anti-SRP+ and anti-HMGCR+myopathies: Role of autoantibodies and complement.

Allenbach Y, Arouche-Delaperche L, Preusse C, Radbruch H, Butler-Browne G, Champtiaux N, Mariampillai K, Rigolet A, Hufnagl P, Zerbe N, Amelin D, Maisonobe T, Louis-Leonard S, Duyckaerts C, Eymard B, Goebel HH, Bergua C, Drouot L, Boyer O, Benveniste O, Stenzel W.

Neurology. 2018 Feb 6;90(6):e507-e517. doi: 10.1212/WNL.0000000000004923. Epub 2018 Jan 12.


The chronically inflamed central nervous system provides niches for long-lived plasma cells.

Pollok K, Mothes R, Ulbricht C, Liebheit A, Gerken JD, Uhlmann S, Paul F, Niesner R, Radbruch H, Hauser AE.

Acta Neuropathol Commun. 2017 Nov 25;5(1):88. doi: 10.1186/s40478-017-0487-8.


Quantitative Imaging of Ca2+ by 3D-FLIM in Live Tissues.

Rakymzhan A, Radbruch H, Niesner RA.

Adv Exp Med Biol. 2017;1035:135-141. doi: 10.1007/978-3-319-67358-5_9.


Analyzing Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation in Aging and Vascular Amyloid Pathology.

Radbruch H, Mothes R, Bremer D, Seifert S, Köhler R, Pohlan J, Ostendorf L, Günther R, Leben R, Stenzel W, Niesner RA, Hauser AE.

Front Immunol. 2017 Jul 31;8:844. doi: 10.3389/fimmu.2017.00844. eCollection 2017.


The enteric nervous system is a potential autoimmune target in multiple sclerosis.

Wunsch M, Jabari S, Voussen B, Enders M, Srinivasan S, Cossais F, Wedel T, Boettner M, Schwarz A, Weyer L, Göcer O, Schroeter M, Maeurer M, Woenckhaus M, Pollok K, Radbruch H, Klotz L, Scholz CJ, Nickel J, Friebe A, Addicks K, Ergün S, Lehmann PV, Kuerten S.

Acta Neuropathol. 2017 Aug;134(2):281-295. doi: 10.1007/s00401-017-1742-6. Epub 2017 Jun 15.


Method to Detect the Cellular Source of Over-Activated NADPH Oxidases Using NAD(P)H Fluorescence Lifetime Imaging.

Bremer D, Leben R, Mothes R, Radbruch H, Niesner R.

Curr Protoc Cytom. 2017 Apr 3;80:9.52.1-9.52.14. doi: 10.1002/cpcy.20.


Histopathologic Assessment of Neurotoxicity after Repeated Administration of Gadodiamide in Healthy Rats.

Schlemm L, Radbruch H, Brandt AU, Scheel M, Paul F.

Radiology. 2017 Mar;282(3):925-926. doi: 10.1148/radiol.2017162394. No abstract available.


Longitudinal Intravital Imaging of the Retina Reveals Long-term Dynamics of Immune Infiltration and Its Effects on the Glial Network in Experimental Autoimmune Uveoretinitis, without Evident Signs of Neuronal Dysfunction in the Ganglion Cell Layer.

Bremer D, Pache F, Günther R, Hornow J, Andresen V, Leben R, Mothes R, Zimmermann H, Brandt AU, Paul F, Hauser AE, Radbruch H, Niesner R.

Front Immunol. 2016 Dec 23;7:642. doi: 10.3389/fimmu.2016.00642. eCollection 2016.


Dendritic cells tip the balance towards induction of regulatory T cells upon priming in experimental autoimmune encephalomyelitis.

Paterka M, Voss JO, Werr J, Reuter E, Franck S, Leuenberger T, Herz J, Radbruch H, Bopp T, Siffrin V, Zipp F.

J Autoimmun. 2017 Jan;76:108-114. doi: 10.1016/j.jaut.2016.09.008. Epub 2016 Oct 2.


Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis.

Kreye J, Wenke NK, Chayka M, Leubner J, Murugan R, Maier N, Jurek B, Ly LT, Brandl D, Rost BR, Stumpf A, Schulz P, Radbruch H, Hauser AE, Pache F, Meisel A, Harms L, Paul F, Dirnagl U, Garner C, Schmitz D, Wardemann H, Prüss H.

Brain. 2016 Oct;139(Pt 10):2641-2652. Epub 2016 Aug 20.


Time lapse in vivo microscopy reveals distinct dynamics of microglia-tumor environment interactions-a new role for the tumor perivascular space as highway for trafficking microglia.

Bayerl SH, Niesner R, Cseresnyes Z, Radbruch H, Pohlan J, Brandenburg S, Czabanka MA, Vajkoczy P.

Glia. 2016 Jul;64(7):1210-26. doi: 10.1002/glia.22994. Epub 2016 May 3.


Ongoing Oxidative Stress Causes Subclinical Neuronal Dysfunction in the Recovery Phase of EAE.

Radbruch H, Bremer D, Guenther R, Cseresnyes Z, Lindquist R, Hauser AE, Niesner R.

Front Immunol. 2016 Mar 14;7:92. doi: 10.3389/fimmu.2016.00092. eCollection 2016.


Poor Sleep in Multiple Sclerosis Correlates with Beck Depression Inventory Values, but Not with Polysomnographic Data.

Veauthier C, Gaede G, Radbruch H, Wernecke KD, Paul F.

Sleep Disord. 2016;2016:8378423. doi: 10.1155/2016/8378423. Epub 2016 Jan 18.


Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation.

Mossakowski AA, Pohlan J, Bremer D, Lindquist R, Millward JM, Bock M, Pollok K, Mothes R, Viohl L, Radbruch M, Gerhard J, Bellmann-Strobl J, Behrens J, Infante-Duarte C, Mähler A, Boschmann M, Rinnenthal JL, Füchtemeier M, Herz J, Pache FC, Bardua M, Priller J, Hauser AE, Paul F, Niesner R, Radbruch H.

Acta Neuropathol. 2015 Dec;130(6):799-814. doi: 10.1007/s00401-015-1497-x. Epub 2015 Oct 31.


Periodic limb movements during REM sleep in multiple sclerosis: a previously undescribed entity.

Veauthier C, Gaede G, Radbruch H, Sieb JP, Wernecke KD, Paul F.

Neuropsychiatr Dis Treat. 2015 Sep 9;11:2323-9. doi: 10.2147/NDT.S83350. eCollection 2015.


Sleep Disorders Reduce Health-Related Quality of Life in Multiple Sclerosis (Nottingham Health Profile Data in Patients with Multiple Sclerosis).

Veauthier C, Gaede G, Radbruch H, Wernecke KD, Paul F.

Int J Mol Sci. 2015 Jul 21;16(7):16514-28. doi: 10.3390/ijms160716514.


Intravital FRET: Probing Cellular and Tissue Function in Vivo.

Radbruch H, Bremer D, Mothes R, Günther R, Rinnenthal JL, Pohlan J, Ulbricht C, Hauser AE, Niesner R.

Int J Mol Sci. 2015 May 21;16(5):11713-27. doi: 10.3390/ijms160511713.


The most fulminant course of the Marburg variant of multiple sclerosis-autopsy findings.

Nunes JC, Radbruch H, Walz R, Lin K, Stenzel W, Prokop S, Koch A, Heppner FL.

Mult Scler. 2015 Apr;21(4):485-7. doi: 10.1177/1352458514537366. Epub 2014 Jun 2.


[Cerebral amyloid angiopathy-related inflammation].

Esfahani-Bayerl N, Radbruch H, Connolly F.

Nervenarzt. 2015 Jun;86(6):748-50. doi: 10.1007/s00115-014-4253-x. German. No abstract available.


MicroRNA-138 is a potential regulator of memory performance in humans.

Schröder J, Ansaloni S, Schilling M, Liu T, Radke J, Jaedicke M, Schjeide BM, Mashychev A, Tegeler C, Radbruch H, Papenberg G, Düzel S, Demuth I, Bucholtz N, Lindenberger U, Li SC, Steinhagen-Thiessen E, Lill CM, Bertram L.

Front Hum Neurosci. 2014 Jul 11;8:501. doi: 10.3389/fnhum.2014.00501. eCollection 2014.


IL-17 and GM-CSF expression are antagonistically regulated by human T helper cells.

Noster R, Riedel R, Mashreghi MF, Radbruch H, Harms L, Haftmann C, Chang HD, Radbruch A, Zielinski CE.

Sci Transl Med. 2014 Jun 18;6(241):241ra80. doi: 10.1126/scitranslmed.3008706.


The role of CD8+ T cells and their local interaction with CD4+ T cells in myelin oligodendrocyte glycoprotein35-55-induced experimental autoimmune encephalomyelitis.

Leuenberger T, Paterka M, Reuter E, Herz J, Niesner RA, Radbruch H, Bopp T, Zipp F, Siffrin V.

J Immunol. 2013 Nov 15;191(10):4960-8. doi: 10.4049/jimmunol.1300822. Epub 2013 Oct 11.


Treatment of sleep disorders may improve fatigue in multiple sclerosis.

Veauthier C, Gaede G, Radbruch H, Gottschalk S, Wernecke KD, Paul F.

Clin Neurol Neurosurg. 2013 Sep;115(9):1826-30. doi: 10.1016/j.clineuro.2013.05.018. Epub 2013 Jun 12.


Parallelized TCSPC for dynamic intravital fluorescence lifetime imaging: quantifying neuronal dysfunction in neuroinflammation.

Rinnenthal JL, Börnchen C, Radbruch H, Andresen V, Mossakowski A, Siffrin V, Seelemann T, Spiecker H, Moll I, Herz J, Hauser AE, Zipp F, Behne MJ, Niesner R.

PLoS One. 2013 Apr 16;8(4):e60100. doi: 10.1371/journal.pone.0060100. Print 2013.


High-resolution intravital microscopy.

Andresen V, Pollok K, Rinnenthal JL, Oehme L, Günther R, Spiecker H, Radbruch H, Gerhard J, Sporbert A, Cseresnyes Z, Hauser AE, Niesner R.

PLoS One. 2012;7(12):e50915. doi: 10.1371/journal.pone.0050915. Epub 2012 Dec 14.


In vivo imaging of lymphocytes in the CNS reveals different behaviour of naïve T cells in health and autoimmunity.

Herz J, Paterka M, Niesner RA, Brandt AU, Siffrin V, Leuenberger T, Birkenstock J, Mossakowski A, Glumm R, Zipp F, Radbruch H.

J Neuroinflammation. 2011 Oct 6;8:131. doi: 10.1186/1742-2094-8-131.


Fatigue in multiple sclerosis is closely related to sleep disorders: a polysomnographic cross-sectional study.

Veauthier C, Radbruch H, Gaede G, Pfueller CF, Dörr J, Bellmann-Strobl J, Wernecke KD, Zipp F, Paul F, Sieb JP.

Mult Scler. 2011 May;17(5):613-22. doi: 10.1177/1352458510393772. Epub 2011 Jan 28.


In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis.

Siffrin V, Radbruch H, Glumm R, Niesner R, Paterka M, Herz J, Leuenberger T, Lehmann SM, Luenstedt S, Rinnenthal JL, Laube G, Luche H, Lehnardt S, Fehling HJ, Griesbeck O, Zipp F.

Immunity. 2010 Sep 24;33(3):424-36. doi: 10.1016/j.immuni.2010.08.018.


Patterns of retinal nerve fiber layer loss in multiple sclerosis patients with or without optic neuritis and glaucoma patients.

Bock M, Brandt AU, Dörr J, Kraft H, Weinges-Evers N, Gaede G, Pfueller CF, Herges K, Radbruch H, Ohlraun S, Bellmann-Strobl J, Kuchenbecker J, Zipp F, Paul F.

Clin Neurol Neurosurg. 2010 Oct;112(8):647-52. doi: 10.1016/j.clineuro.2010.04.014. Epub 2010 May 10.


Expanding two-photon intravital microscopy to the infrared by means of optical parametric oscillator.

Herz J, Siffrin V, Hauser AE, Brandt AU, Leuenberger T, Radbruch H, Zipp F, Niesner RA.

Biophys J. 2010 Feb 17;98(4):715-23. doi: 10.1016/j.bpj.2009.10.035.


Multiple sclerosis - candidate mechanisms underlying CNS atrophy.

Siffrin V, Vogt J, Radbruch H, Nitsch R, Zipp F.

Trends Neurosci. 2010 Apr;33(4):202-10. doi: 10.1016/j.tins.2010.01.002. Epub 2010 Feb 12. Review.


Attention Network Test reveals alerting network dysfunction in multiple sclerosis.

Urbanek C, Weinges-Evers N, Bellmann-Strobl J, Bock M, Dörr J, Hahn E, Neuhaus AH, Opgen-Rhein C, Ta TM, Herges K, Pfueller CF, Radbruch H, Wernecke KD, Ohlraun S, Zipp F, Dettling M, Paul F.

Mult Scler. 2010 Jan;16(1):93-9. doi: 10.1177/1352458509350308. Epub 2009 Dec 7.


Encephalopathy, visual disturbance and hearing loss-recognizing the symptoms of Susac syndrome.

Dörr J, Radbruch H, Bock M, Wuerfel J, Brüggemann A, Wandinger KP, Zeise D, Pfueller CF, Zipp F, Paul F.

Nat Rev Neurol. 2009 Dec;5(12):683-8. doi: 10.1038/nrneurol.2009.176.


Differential immune cell dynamics in the CNS cause CD4+ T cell compartmentalization.

Siffrin V, Brandt AU, Radbruch H, Herz J, Boldakowa N, Leuenberger T, Werr J, Hahner A, Schulze-Topphoff U, Nitsch R, Zipp F.

Brain. 2009 May;132(Pt 5):1247-58. doi: 10.1093/brain/awn354. Epub 2009 Jan 29.


Autoregulation of Th1-mediated inflammation by twist1.

Niesner U, Albrecht I, Janke M, Doebis C, Loddenkemper C, Lexberg MH, Eulenburg K, Kreher S, Koeck J, Baumgrass R, Bonhagen K, Kamradt T, Enghard P, Humrich JY, Rutz S, Schulze-Topphoff U, Aktas O, Bartfeld S, Radbruch H, Hegazy AN, Löhning M, Baumgart DC, Duchmann R, Rudwaleit M, Häupl T, Gitelman I, Krenn V, Gruen J, Sieper J, Zeitz M, Wiedenmann B, Zipp F, Hamann A, Janitz M, Scheffold A, Burmester GR, Chang HD, Radbruch A.

J Exp Med. 2008 Aug 4;205(8):1889-901. doi: 10.1084/jem.20072468. Epub 2008 Jul 28.

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