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Items: 1 to 50 of 84

1.

Gender differences in sexual and reproductive health education in the family: a mixed methods study on Romanian young people.

Faludi C, Rada C.

BMC Public Health. 2019 Aug 14;19(1):1103. doi: 10.1186/s12889-019-7321-0.

2.

Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues.

Chandler LC, Barnard AR, Caddy SL, Patrício MI, McClements ME, Fu H, Rada C, MacLaren RE, Xue K.

Mol Ther Methods Clin Dev. 2019 Jun 4;14:77-89. doi: 10.1016/j.omtm.2019.05.012. eCollection 2019 Sep 13.

3.

Aicardi-Goutières Syndrome associated mutations of RNase H2B impair its interaction with ZMYM3 and the CoREST histone-modifying complex.

Shapson-Coe A, Valeiras B, Wall C, Rada C.

PLoS One. 2019 Mar 19;14(3):e0213553. doi: 10.1371/journal.pone.0213553. eCollection 2019.

4.

G protein-coupled receptors activate p38 MAPK via a non-canonical TAB1-TAB2- and TAB1-TAB3-dependent pathway in endothelial cells.

Grimsey NJ, Lin Y, Narala R, Rada CC, Mejia-Pena H, Trejo J.

J Biol Chem. 2019 Apr 12;294(15):5867-5878. doi: 10.1074/jbc.RA119.007495. Epub 2019 Feb 13.

5.

A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling.

Grimsey NJ, Narala R, Rada CC, Mehta S, Stephens BS, Kufareva I, Lapek J, Gonzalez DJ, Handel TM, Zhang J, Trejo J.

Cell Rep. 2018 Sep 18;24(12):3312-3323.e5. doi: 10.1016/j.celrep.2018.08.061.

6.

Apobec2 deficiency causes mitochondrial defects and mitophagy in skeletal muscle.

Sato Y, Ohtsubo H, Nihei N, Kaneko T, Sato Y, Adachi SI, Kondo S, Nakamura M, Mizunoya W, Iida H, Tatsumi R, Rada C, Yoshizawa F.

FASEB J. 2018 Mar;32(3):1428-1439. doi: 10.1096/fj.201700493R. Epub 2018 Jan 3.

7.

Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.

Alsøe L, Sarno A, Carracedo S, Domanska D, Dingler F, Lirussi L, SenGupta T, Tekin NB, Jobert L, Alexandrov LB, Galashevskaya A, Rada C, Sandve GK, Rognes T, Krokan HE, Nilsen H.

Sci Rep. 2017 Aug 3;7(1):7199. doi: 10.1038/s41598-017-07314-5.

8.

Intrinsic transcriptional heterogeneity in B cells controls early class switching to IgE.

Wu YL, Stubbington MJ, Daly M, Teichmann SA, Rada C.

J Exp Med. 2017 Jan;214(1):183-196. doi: 10.1084/jem.20161056. Epub 2016 Dec 19.

9.

[Ankle-brachial index screening for peripheral artery disease in high cardiovascular risk patients. Prospective observational study of 370 asymptomatic patients at high cardiovascular risk].

Rada C, Oummou S, Merzouk F, Amarir B, Boussabnia G, Bougrini H, Benzaroual D, Elkarimi S, Elhattaoui M.

J Mal Vasc. 2016 Dec;41(6):353-357. doi: 10.1016/j.jmv.2016.10.003. Epub 2016 Nov 16. French.

PMID:
27865565
10.
11.

Harnessing mutation: The best of two worlds.

Conticello SG, Rada C.

Science. 2016 Sep 16;353(6305):1206-7. doi: 10.1126/science.aai8233. No abstract available.

PMID:
27634511
12.

The topography of mutational processes in breast cancer genomes.

Morganella S, Alexandrov LB, Glodzik D, Zou X, Davies H, Staaf J, Sieuwerts AM, Brinkman AB, Martin S, Ramakrishna M, Butler A, Kim HY, Borg Å, Sotiriou C, Futreal PA, Campbell PJ, Span PN, Van Laere S, Lakhani SR, Eyfjord JE, Thompson AM, Stunnenberg HG, van de Vijver MJ, Martens JW, Børresen-Dale AL, Richardson AL, Kong G, Thomas G, Sale J, Rada C, Stratton MR, Birney E, Nik-Zainal S.

Nat Commun. 2016 May 2;7:11383. doi: 10.1038/ncomms11383.

13.

Molecular fine-tuning of affinity maturation in germinal centers.

Wu YL, Rada C.

J Clin Invest. 2016 Jan;126(1):32-4. doi: 10.1172/JCI85627. Epub 2015 Dec 14.

14.

Directed evolution of human scFvs in DT40 cells.

Lim AW, Williams GT, Rada C, Sale JE.

Protein Eng Des Sel. 2016 Feb;29(2):39-48. doi: 10.1093/protein/gzv058. Epub 2015 Oct 30.

15.

Mutagenesis by AID: Being in the Right Place at the Right Time.

Rada C.

PLoS Genet. 2015 Sep 10;11(9):e1005489. doi: 10.1371/journal.pgen.1005489. eCollection 2015 Sep. No abstract available.

16.

CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex.

van Maldegem F, Maslen S, Johnson CM, Chandra A, Ganesh K, Skehel M, Rada C.

Nucleic Acids Res. 2015 Aug 18;43(14):7058-69. doi: 10.1093/nar/gkv643. Epub 2015 Jun 29.

17.

Intrauterine telemetry to measure mouse contractile pressure in vivo.

Rada CC, Pierce SL, Grotegut CA, England SK.

J Vis Exp. 2015 Apr 6;(98):e52541. doi: 10.3791/52541.

18.

Evaluation of the psychoneurotic tendencies risk using the woodworth mathews personality inventory in non-institutionalized persons.

Pîrlog MC, Rada C, Prejbeanu I, Cara ML.

Curr Health Sci J. 2014 Jul-Sep;40(3):177-83. doi: 10.12865/CHSJ.40.03.04. Epub 2014 Aug 4.

19.

The SK3 channel promotes placental vascularization by enhancing secretion of angiogenic factors.

Rada CC, Murray G, England SK.

Am J Physiol Endocrinol Metab. 2014 Nov 15;307(10):E935-43. doi: 10.1152/ajpendo.00319.2014. Epub 2014 Sep 23.

20.
21.

The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy.

McCloskey C, Rada C, Bailey E, McCavera S, van den Berg HA, Atia J, Rand DA, Shmygol A, Chan YW, Quenby S, Brosens JJ, Vatish M, Zhang J, Denton JS, Taggart MJ, Kettleborough C, Tickle D, Jerman J, Wright P, Dale T, Kanumilli S, Trezise DJ, Thornton S, Brown P, Catalano R, Lin N, England SK, Blanks AM.

EMBO Mol Med. 2014 Sep;6(9):1161-74. doi: 10.15252/emmm.201403944.

22.
23.

Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation.

Dingler FA, Kemmerich K, Neuberger MS, Rada C.

Eur J Immunol. 2014 Jul;44(7):1925-35. doi: 10.1002/eji.201444482. Epub 2014 May 27.

25.

Age at initiation of sexual life, protection at first intercourse and sources of information regarding sexual and reproductive health.

Rada C, Albu A, Petrariu FD.

Rev Med Chir Soc Med Nat Iasi. 2013 Oct-Dec;117(4):994-1001.

PMID:
24502081
26.

Active demethylation in mouse zygotes involves cytosine deamination and base excision repair.

Santos F, Peat J, Burgess H, Rada C, Reik W, Dean W.

Epigenetics Chromatin. 2013 Nov 14;6(1):39. doi: 10.1186/1756-8935-6-39.

27.

Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin α.

Ganesh K, van Maldegem F, Telerman SB, Simpson P, Johnson CM, Williams RL, Neuberger MS, Rada C.

FEBS Lett. 2014 Jan 3;588(1):21-7. doi: 10.1016/j.febslet.2013.11.013. Epub 2013 Nov 20.

28.

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis.

Taylor BJ, Nik-Zainal S, Wu YL, Stebbings LA, Raine K, Campbell PJ, Rada C, Stratton MR, Neuberger MS.

Elife. 2013 Apr 16;2:e00534. doi: 10.7554/eLife.00534.

29.

First-trimester serum soluble fms-like tyrosine kinase-1, free vascular endothelial growth factor, placental growth factor and uterine artery Doppler in preeclampsia.

Odibo AO, Rada CC, Cahill AG, Goetzinger KR, Tuuli MG, Odibo L, Macones GA, England SK.

J Perinatol. 2013 Sep;33(9):670-4. doi: 10.1038/jp.2013.33. Epub 2013 Apr 4.

PMID:
23558430
30.

Deficiency in spliceosome-associated factor CTNNBL1 does not affect ongoing cell cycling but delays exit from quiescence and results in embryonic lethality in mice.

Chandra A, van Maldegem F, Andrews S, Neuberger MS, Rada C.

Cell Cycle. 2013 Mar 1;12(5):732-42. doi: 10.4161/cc.23594. Epub 2013 Jan 23.

31.

Overexpression of the SK3 channel alters vascular remodeling during pregnancy, leading to fetal demise.

Rada CC, Pierce SL, Nuno DW, Zimmerman K, Lamping KG, Bowdler NC, Weiss RM, England SK.

Am J Physiol Endocrinol Metab. 2012 Oct 1;303(7):E825-31. doi: 10.1152/ajpendo.00165.2012. Epub 2012 Jul 11.

32.

The cytoplasmic AID complex.

Häsler J, Rada C, Neuberger MS.

Semin Immunol. 2012 Aug;24(4):273-80. doi: 10.1016/j.smim.2012.05.004. Epub 2012 Jun 13. Review.

PMID:
22698843
33.

Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.

Kemmerich K, Dingler FA, Rada C, Neuberger MS.

Nucleic Acids Res. 2012 Jul;40(13):6016-25. doi: 10.1093/nar/gks259. Epub 2012 Mar 24.

34.

REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase.

Uchimura Y, Barton LF, Rada C, Neuberger MS.

J Exp Med. 2011 Nov 21;208(12):2385-91. doi: 10.1084/jem.20110856. Epub 2011 Oct 31.

35.

Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1α (eEF1A).

Häsler J, Rada C, Neuberger MS.

Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18366-71. doi: 10.1073/pnas.1106729108. Epub 2011 Oct 31.

36.

[Food intake--family income in a group of teenagers from Iaşi "Dimitrie Cantemir" High School].

Indrei LL, Rada C, Albu A, Crăcană I, Albu A.

Rev Med Chir Soc Med Nat Iasi. 2011 Jan-Mar;115(1):181-5. Romanian.

PMID:
21688575
37.

ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma.

Loizou JI, Sancho R, Kanu N, Bolland DJ, Yang F, Rada C, Corcoran AE, Behrens A.

Cancer Cell. 2011 May 17;19(5):587-600. doi: 10.1016/j.ccr.2011.03.022.

38.

Altered contribution of RhoA/Rho kinase signaling in contractile activity of myometrium in leptin receptor-deficient mice.

Harrod JS, Rada CC, Pierce SL, England SK, Lamping KG.

Am J Physiol Endocrinol Metab. 2011 Aug;301(2):E362-9. doi: 10.1152/ajpendo.00696.2010. Epub 2011 May 10.

39.

[Smoking, alcohol consumption and pregnancy in a population of south-western Romania].

Prejbeanu I, Rada C, Indrei LL, Cara ML, Mihai M, Dragomir M, Pîrlog M.

Rev Med Chir Soc Med Nat Iasi. 2010 Oct-Dec;114(4):1148-54. Romanian.

PMID:
21500472
40.

Evaluation of women knowledge and attitude regarding cervical cancer early detection.

Bădulescu F, Prejbeanu I, Rada C, Pătraşcu A, Dragomir M, Popescu FC.

Rom J Morphol Embryol. 2011;52(1):45-51.

41.

CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31.

Ganesh K, Adam S, Taylor B, Simpson P, Rada C, Neuberger M.

J Biol Chem. 2011 May 13;286(19):17091-102. doi: 10.1074/jbc.M110.208769. Epub 2011 Mar 8.

42.

A high-throughput assay for DNA deaminases.

Wang M, Rada C, Neuberger MS.

Methods Mol Biol. 2011;718:171-84. doi: 10.1007/978-1-61779-018-8_11.

PMID:
21370049
43.

The dependence of Ig class-switching on the nuclear export sequence of AID likely reflects interaction with factors additional to Crm1 exportin.

Ellyard JI, Benk AS, Taylor B, Rada C, Neuberger MS.

Eur J Immunol. 2011 Feb;41(2):485-90. doi: 10.1002/eji.201041011. Epub 2010 Dec 23.

44.

Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID.

Wang M, Rada C, Neuberger MS.

J Exp Med. 2010 Jan 18;207(1):141-53. doi: 10.1084/jem.20092238. Epub 2010 Jan 4.

45.

Deficiency in APOBEC2 leads to a shift in muscle fiber type, diminished body mass, and myopathy.

Sato Y, Probst HC, Tatsumi R, Ikeuchi Y, Neuberger MS, Rada C.

J Biol Chem. 2010 Mar 5;285(10):7111-8. doi: 10.1074/jbc.M109.052977. Epub 2009 Dec 17.

46.

The AKV murine leukemia virus is restricted and hypermutated by mouse APOBEC3.

Langlois MA, Kemmerich K, Rada C, Neuberger MS.

J Virol. 2009 Nov;83(22):11550-9. doi: 10.1128/JVI.01430-09. Epub 2009 Sep 2.

47.

AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity.

Wang M, Yang Z, Rada C, Neuberger MS.

Nat Struct Mol Biol. 2009 Jul;16(7):769-76. doi: 10.1038/nsmb.1623. Epub 2009 Jun 21.

48.

The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence.

Geisberger R, Rada C, Neuberger MS.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6736-41. doi: 10.1073/pnas.0810808106. Epub 2009 Apr 7.

49.

[Fruit consumption in a group of teenagers from Iaşi].

Albul A, Rada C, Albu M, Indrei LL.

Rev Med Chir Soc Med Nat Iasi. 2009 Apr-Jun;113(2):554-7. Romanian.

PMID:
21495365
50.

AID and RPA: PKA makes the connection local.

Rada C.

Nat Immunol. 2009 Apr;10(4):367-9. doi: 10.1038/ni0409-367. No abstract available.

PMID:
19295635

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