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Items: 1 to 50 of 942

1.

T Cell Activation Depends on Extracellular Alanine.

Ron-Harel N, Ghergurovich JM, Notarangelo G, LaFleur MW, Tsubosaka Y, Sharpe AH, Rabinowitz JD, Haigis MC.

Cell Rep. 2019 Sep 17;28(12):3011-3021.e4. doi: 10.1016/j.celrep.2019.08.034.

PMID:
31533027
2.

Physician experience is associated with greater underestimation of patient pain.

Miron-Shatz T, Ormianer M, Rabinowitz J, Hanoch Y, Tsafrir A.

Patient Educ Couns. 2019 Aug 30. pii: S0738-3991(19)30382-9. doi: 10.1016/j.pec.2019.08.040. [Epub ahead of print]

PMID:
31526533
3.

Low-dose ladostigil for mild cognitive impairment: A phase 2 placebo-controlled clinical trial.

Schneider LS, Geffen Y, Rabinowitz J, Thomas RG, Schmidt R, Ropele S, Weinstock M; Ladostigil Study Group.

Neurology. 2019 Sep 6. pii: 10.1212/WNL.0000000000008239. doi: 10.1212/WNL.0000000000008239. [Epub ahead of print]

PMID:
31492718
4.

Author Correction: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function.

Bailis W, Shyer JA, Zhao J, Canaveras JCG, Al Khazal FJ, Qu R, Steach HR, Bielecki P, Khan O, Jackson R, Kluger Y, Maher LJ 3rd, Rabinowitz J, Craft J, Flavell RA.

Nature. 2019 Sep;573(7773):E2. doi: 10.1038/s41586-019-1490-y.

PMID:
31447485
5.

Informant Discrepancies in Internalizing and Externalizing Symptoms in an At-Risk Sample: The Role of Parenting and School Engagement.

Curhan AL, Rabinowitz JA, Pas ET, Bradshaw CP.

J Youth Adolesc. 2019 Aug 24. doi: 10.1007/s10964-019-01107-x. [Epub ahead of print]

PMID:
31446584
6.

Model-Informed Approach to Assess the Treatment Effect Conditional to the Level of Placebo Response.

Gomeni R, Rabinowitz J, Goyal N, Bressolle-Gomeni FMM, Fava M.

Clin Pharmacol Ther. 2019 Aug 9. doi: 10.1002/cpt.1584. [Epub ahead of print]

PMID:
31397904
7.

Personal and social adjustment effects of roluperidone in patients with schizophrenia and negative symptoms: Results from an exploratory outcome of a randomized placebo-controlled trial.

Rabinowitz J, Badescu S, Palamarchuk P, Filyk V, Voloshchuk A, Rud V, Melnyk E, Skrypnikov A, Davidson M, Saoud J, Luthringer R.

Schizophr Res. 2019 Sep;211:103-104. doi: 10.1016/j.schres.2019.07.029. Epub 2019 Jul 30. No abstract available.

PMID:
31375316
8.

Novel pyrrolo[3,2-d]pyrimidine compounds target mitochondrial and cytosolic one-carbon metabolism with broad-spectrum antitumor efficacy.

Dekhne AS, Shah K, Ducker GS, Katinas JM, Wong-Roushar J, Nayeen MJ, Doshi A, Ning C, Bao X, Frühauf J, Liu J, Wallace-Povirk A, O'Connor C, Dzinic SH, White K, Kushner J, Kim S, Hüttemann M, Polin L, Rabinowitz JD, Li J, Hou Z, Dann CE, Gangjee A, Matherly LH.

Mol Cancer Ther. 2019 Jul 9. pii: molcanther.0037.2019. doi: 10.1158/1535-7163.MCT-19-0037. [Epub ahead of print]

PMID:
31289137
9.

Nanoscale Fluid Vortices and Nonlinear Electroosmotic Flow Drive Ion Current Rectification in the Presence of Concentration Gradients.

Rabinowitz J, Edwards MA, Whittier E, Jayant K, Shepard KL.

J Phys Chem A. 2019 Jul 16. doi: 10.1021/acs.jpca.9b04075. [Epub ahead of print]

PMID:
31264868
10.

Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity.

Liu Q, Johnson EM, Lam RK, Wang Q, Bo Ye H, Wilson EN, Minhas PS, Liu L, Swarovski MS, Tran S, Wang J, Mehta SS, Yang X, Rabinowitz JD, Yang SS, Shamloo M, Mueller C, James ML, Andreasson KI.

Nat Immunol. 2019 Aug;20(8):1023-1034. doi: 10.1038/s41590-019-0421-2. Epub 2019 Jul 1.

PMID:
31263278
11.

Metabolite Exchange between Mammalian Organs Quantified in Pigs.

Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, Morscher RJ, Reyes J, Frezza C, Hwang HY, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, Zsido GA 2nd, Gorman JH 3rd, Gorman RC, Rabinowitz JD.

Cell Metab. 2019 Sep 3;30(3):594-606.e3. doi: 10.1016/j.cmet.2019.06.002. Epub 2019 Jun 27.

12.

Polygenic and environmental influences on the course of African Americans' alcohol use from early adolescence through young adulthood.

Rabinowitz JA, Musci RJ, Reboussin B, Milam AJ, Benke KS, Uhl GR, Sisto DY, Ialongo NS, Maher BS.

Dev Psychopathol. 2019 Jul 1:1-16. doi: 10.1017/S0954579419000701. [Epub ahead of print]

PMID:
31256767
13.

Does Negative Emotional Reactivity Moderate the Relation between Contextual Cohesion and Adolescent Well-Being?

Myerberg LB, Rabinowitz JA, Reynolds MD, Drabick DAG.

J Youth Adolesc. 2019 Jun 26. doi: 10.1007/s10964-019-01053-8. [Epub ahead of print]

PMID:
31254241
14.

Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function.

Bailis W, Shyer JA, Zhao J, Canaveras JCG, Al Khazal FJ, Qu R, Steach HR, Bielecki P, Khan O, Jackson R, Kluger Y, Maher LJ 3rd, Rabinowitz J, Craft J, Flavell RA.

Nature. 2019 Jul;571(7765):403-407. doi: 10.1038/s41586-019-1311-3. Epub 2019 Jun 19. Erratum in: Nature. 2019 Sep;573(7773):E2.

PMID:
31217581
15.

Energy budget of Drosophila embryogenesis.

Song Y, Park JO, Tanner L, Nagano Y, Rabinowitz JD, Shvartsman SY.

Curr Biol. 2019 Jun 17;29(12):R566-R567. doi: 10.1016/j.cub.2019.05.025.

PMID:
31211973
16.

A Two-Enzyme Adaptive Unit within Bacterial Folate Metabolism.

Schober AF, Mathis AD, Ingle C, Park JO, Chen L, Rabinowitz JD, Junier I, Rivoire O, Reynolds KA.

Cell Rep. 2019 Jun 11;27(11):3359-3370.e7. doi: 10.1016/j.celrep.2019.05.030.

17.

Consistency checks to improve measurement with the Montgomery-Asberg Depression Rating Scale (MADRS).

Rabinowitz J, Schooler NR, Brown B, Dalsgaard M, Engelhardt N, Friedberger G, Kinon BJ, Lee D, Ockun F, Mahableshwarkar A, Tsai J, Williams JBW, Sauder C, Yavorsky C; ISCTM ALGORITHMS/FLAGS TO IDENTIFY CLINICAL INCONSISTENCY IN THE USE OF RATING SCALES IN CNS RCTs working group members.

J Affect Disord. 2019 Sep 1;256:143-147. doi: 10.1016/j.jad.2019.05.077. Epub 2019 Jun 1.

18.

The Tumor Metabolic Microenvironment: Lessons from Lactate.

García-Cañaveras JC, Chen L, Rabinowitz JD.

Cancer Res. 2019 Jul 1;79(13):3155-3162. doi: 10.1158/0008-5472.CAN-18-3726. Epub 2019 Jun 6. Review.

PMID:
31171526
19.

A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate.

Wang W, Ishibashi J, Trefely S, Shao M, Cowan AJ, Sakers A, Lim HW, O'Connor S, Doan MT, Cohen P, Baur JA, King MT, Veech RL, Won KJ, Rabinowitz JD, Snyder NW, Gupta RK, Seale P.

Cell Metab. 2019 Jul 2;30(1):174-189.e5. doi: 10.1016/j.cmet.2019.05.005. Epub 2019 May 30.

PMID:
31155495
20.

The metabolites NADP+ and NADPH are the targets of the circadian protein Nocturnin (Curled).

Estrella MA, Du J, Chen L, Rath S, Prangley E, Chitrakar A, Aoki T, Schedl P, Rabinowitz J, Korennykh A.

Nat Commun. 2019 May 30;10(1):2367. doi: 10.1038/s41467-019-10125-z.

21.

NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism.

Chen L, Zhang Z, Hoshino A, Zheng HD, Morley M, Arany Z, Rabinowitz JD.

Nat Metab. 2019 Mar;1:404-415. Epub 2019 Mar 11.

22.

Social Influences on Drinking Trajectories From Adolescence to Young Adulthood in an Urban Minority Sample.

Reboussin BA, Furr-Holden DM, Green KM, Ialongo NS, Rabinowitz JA, Matson PA, Maher B, Nelson V, Milam AJ.

J Stud Alcohol Drugs. 2019 Mar;80(2):186-195.

PMID:
31014463
23.

Minor Isozymes Tailor Yeast Metabolism to Carbon Availability.

Bradley PH, Gibney PA, Botstein D, Troyanskaya OG, Rabinowitz JD.

mSystems. 2019 Feb 26;4(1). pii: e00170-18. doi: 10.1128/mSystems.00170-18. eCollection 2019 Jan-Feb.

24.

Contributions of an Internalizing Symptoms Polygenic Risk Score and Contextual Factors to Alcohol-Related Disorders in African American Young Adults.

Rabinowitz JA, Musci R, Milam A, Benke K, Sisto D, Ialongo NS, Maher BS, Uhl G, Rosenbaum G, Reboussin B.

J Stud Alcohol Drugs. 2019 Jan;80(1):77-85.

PMID:
30807278
25.

Associations between an educational attainment polygenic score with educational attainment in an African American sample.

Rabinowitz JA, Kuo SI, Felder W, Musci RJ, Bettencourt A, Benke K, Sisto DY, Smail E, Uhl G, Maher BS, Kouzis A, Ialongo NS.

Genes Brain Behav. 2019 Jun;18(5):e12558. doi: 10.1111/gbb.12558. Epub 2019 Mar 12.

PMID:
30793481
26.

Serine Metabolism Supports Macrophage IL-1β Production.

Rodriguez AE, Ducker GS, Billingham LK, Martinez CA, Mainolfi N, Suri V, Friedman A, Manfredi MG, Weinberg SE, Rabinowitz JD, Chandel NS.

Cell Metab. 2019 Apr 2;29(4):1003-1011.e4. doi: 10.1016/j.cmet.2019.01.014. Epub 2019 Feb 14.

PMID:
30773464
27.

Profiles of caregiving behaviors among children and adolescents with perinatally acquired HIV.

Rabinowitz JA, Osigwe I, Godshalk L, Drabick DAG, Nachman S, Gadow KD.

AIDS Care. 2019 Jun;31(6):737-745. doi: 10.1080/09540121.2019.1576850. Epub 2019 Feb 7.

PMID:
30732458
28.

Adeno-associated Virus (AAV) versus Immune Response.

Rabinowitz J, Chan YK, Samulski RJ.

Viruses. 2019 Jan 25;11(2). pii: E102. doi: 10.3390/v11020102. Review.

29.

Flexible Nanopipettes for Minimally Invasive Intracellular Electrophysiology In Vivo.

Jayant K, Wenzel M, Bando Y, Hamm JP, Mandriota N, Rabinowitz JH, Plante IJ, Owen JS, Sahin O, Shepard KL, Yuste R.

Cell Rep. 2019 Jan 2;26(1):266-278.e5. doi: 10.1016/j.celrep.2018.12.019.

30.

Peak Annotation and Verification Engine for Untargeted LC-MS Metabolomics.

Wang L, Xing X, Chen L, Yang L, Su X, Rabitz H, Lu W, Rabinowitz JD.

Anal Chem. 2019 Feb 5;91(3):1838-1846. doi: 10.1021/acs.analchem.8b03132. Epub 2019 Jan 10.

PMID:
30586294
31.

Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice.

Ron-Harel N, Notarangelo G, Ghergurovich JM, Paulo JA, Sage PT, Santos D, Satterstrom FK, Gygi SP, Rabinowitz JD, Sharpe AH, Haigis MC.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):13347-13352. doi: 10.1073/pnas.1804149115. Epub 2018 Dec 10.

32.

Author Correction: Autophagy maintains tumour growth through circulating arginine.

Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, Rabinowitz JD, White E.

Nature. 2019 Jan;565(7737):E3. doi: 10.1038/s41586-018-0815-6.

PMID:
30523330
33.

Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation.

Minhas PS, Liu L, Moon PK, Joshi AU, Dove C, Mhatre S, Contrepois K, Wang Q, Lee BA, Coronado M, Bernstein D, Snyder MP, Migaud M, Majeti R, Mochly-Rosen D, Rabinowitz JD, Andreasson KI.

Nat Immunol. 2019 Jan;20(1):50-63. doi: 10.1038/s41590-018-0255-3. Epub 2018 Nov 26.

PMID:
30478397
34.

Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids.

Neinast MD, Jang C, Hui S, Murashige DS, Chu Q, Morscher RJ, Li X, Zhan L, White E, Anthony TG, Rabinowitz JD, Arany Z.

Cell Metab. 2019 Feb 5;29(2):417-429.e4. doi: 10.1016/j.cmet.2018.10.013. Epub 2018 Nov 15.

PMID:
30449684
35.

Autophagy maintains tumour growth through circulating arginine.

Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, Rabinowitz JD, White E.

Nature. 2018 Nov;563(7732):569-573. doi: 10.1038/s41586-018-0697-7. Epub 2018 Nov 14. Erratum in: Nature. 2018 Dec 6;:.

36.

Negative Consequences Associated With Witnessing Severe Violent Events: The Role of Control-Related Beliefs.

Musci RJ, Bettencourt AF, Rabinowitz J, Ialongo NS, Lambert SF.

J Adolesc Health. 2018 Dec;63(6):739-744. doi: 10.1016/j.jadohealth.2018.07.001. Epub 2018 Oct 4.

PMID:
30293863
37.

Individual and Neighborhood Factors Associated With Sexual Behavior Classes in an Urban Longitudinal Sample.

Green KM, Matson PA, Reboussin BA, Milam AJ, Furr-Holden CDM, Rabinowitz JA, Powell TW, Ialongo NS.

Sex Transm Dis. 2019 Feb;46(2):98-104. doi: 10.1097/OLQ.0000000000000920.

PMID:
30278028
38.

Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase.

Xu YF, Lu W, Chen JC, Johnson SA, Gibney PA, Thomas DG, Brown G, May AL, Campagna SR, Yakunin AF, Botstein D, Rabinowitz JD.

ACS Chem Biol. 2018 Oct 19;13(10):3011-3020. doi: 10.1021/acschembio.8b00804. Epub 2018 Oct 4.

PMID:
30240188
39.

The interplay between externalizing disorders polygenic risk scores and contextual factors on the development of marijuana use disorders.

Rabinowitz JA, Musci RJ, Milam AJ, Benke K, Uhl GR, Sisto DY, Ialongo NS, Maher BS.

Drug Alcohol Depend. 2018 Oct 1;191:365-373. doi: 10.1016/j.drugalcdep.2018.07.016. Epub 2018 Aug 25.

PMID:
30195949
40.

Psychiatric symptoms and related dysfunction in a general population sample.

Smith L, Reichenberg A, Rabinowitz J, Levine SZ, Velthorst E.

Schizophr Res Cogn. 2018 Aug 11;14:1-6. doi: 10.1016/j.scog.2018.08.001. eCollection 2018 Dec.

41.

An unexpected trigger for calorie burning in brown fat.

Hui S, Rabinowitz JD.

Nature. 2018 Aug;560(7716):38-39. doi: 10.1038/d41586-018-05619-7. No abstract available.

PMID:
30061641
42.

Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes.

Guan D, Xiong Y, Borck PC, Jang C, Doulias PT, Papazyan R, Fang B, Jiang C, Zhang Y, Briggs ER, Hu W, Steger D, Ischiropoulos H, Rabinowitz JD, Lazar MA.

Cell. 2018 Aug 9;174(4):831-842.e12. doi: 10.1016/j.cell.2018.06.031. Epub 2018 Jul 26.

43.

Escherichia coli translation strategies differ across carbon, nitrogen and phosphorus limitation conditions.

Li SH, Li Z, Park JO, King CG, Rabinowitz JD, Wingreen NS, Gitai Z.

Nat Microbiol. 2018 Aug;3(8):939-947. doi: 10.1038/s41564-018-0199-2. Epub 2018 Jul 23.

44.

5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination.

Rodan LH, Qi W, Ducker GS, Demirbas D, Laine R, Yang E, Walker MA, Eichler F, Rabinowitz JD, Anselm I, Berry GT; Undiagnosed Diseases Network (UDN).

Mol Genet Metab. 2018 Sep;125(1-2):118-126. doi: 10.1016/j.ymgme.2018.06.006. Epub 2018 Jun 15.

45.

Determinants of antidepressant response: Implications for practice and future clinical trials.

Rabinowitz J, Werbeloff N, Mandel FS, Marangell L, Menard F, Kapur S.

J Affect Disord. 2018 Oct 15;239:79-84. doi: 10.1016/j.jad.2018.06.039. Epub 2018 Jul 2.

PMID:
29990666
46.

Four Key Steps Control Glycolytic Flux in Mammalian Cells.

Tanner LB, Goglia AG, Wei MH, Sehgal T, Parsons LR, Park JO, White E, Toettcher JE, Rabinowitz JD.

Cell Syst. 2018 Jul 25;7(1):49-62.e8. doi: 10.1016/j.cels.2018.06.003. Epub 2018 Jun 27.

47.

Publisher Correction: Targeting hepatic glutaminase activity to ameliorate hyperglycemia.

Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ.

Nat Med. 2018 Sep;24(9):1482. doi: 10.1038/s41591-018-0047-1.

PMID:
29895835
48.

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria.

Davila A, Liu L, Chellappa K, Redpath P, Nakamaru-Ogiso E, Paolella LM, Zhang Z, Migaud ME, Rabinowitz JD, Baur JA.

Elife. 2018 Jun 12;7. pii: e33246. doi: 10.7554/eLife.33246.

49.

Ribosomes on the night shift.

Nofal M, Rabinowitz JD.

Science. 2018 May 18;360(6390):710-711. doi: 10.1126/science.aat7121. No abstract available.

PMID:
29773733
50.

Rapid experimental measurements of physicochemical properties to inform models and testing.

Nicolas CI, Mansouri K, Phillips KA, Grulke CM, Richard AM, Williams AJ, Rabinowitz J, Isaacs KK, Yau A, Wambaugh JF.

Sci Total Environ. 2018 Sep 15;636:901-909. doi: 10.1016/j.scitotenv.2018.04.266. Epub 2018 May 2.

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