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Risk of serious infection among individuals with and without low count monoclonal B-cell lymphocytosis (MBL).

Shanafelt TD, Kay NE, Parikh SA, Achenbach SJ, Lesnick CE, Hanson CA, Kleinstern G, Olson JE, Norman AD, Rabe KG, Schwager SM, Call TG, Slager SL.

Leukemia. 2020 Mar 18. doi: 10.1038/s41375-020-0799-8. [Epub ahead of print] No abstract available.


The impact of dose modification and temporary interruption of ibrutinib on outcomes of chronic lymphocytic leukemia patients in routine clinical practice.

Parikh SA, Achenbach SJ, Call TG, Rabe KG, Ding W, Leis JF, Kenderian SS, Chanan-Khan AA, Koehler AB, Schwager SM, Muchtar E, Fonder AL, McCullough KB, Nedved AN, Smith MD, Slager SL, Kay NE, Finnes HD, Shanafelt TD.

Cancer Med. 2020 Mar 18. doi: 10.1002/cam4.2998. [Epub ahead of print]


Surface Display of Complex Enzymes by In Situ SpyCatcher-SpyTag Interaction.

Gallus S, Peschke T, Paulsen M, Burgahn T, Niemeyer CM, Rabe KS.

Chembiochem. 2020 Mar 17. doi: 10.1002/cbic.202000102. [Epub ahead of print]


Valency engineering of monomeric enzymes for self-assembling biocatalytic hydrogels.

Bitterwolf P, Gallus S, Peschke T, Mittmann E, Oelschlaeger C, Willenbacher N, Rabe KS, Niemeyer CM.

Chem Sci. 2019 Sep 6;10(42):9752-9757. doi: 10.1039/c9sc04074a. eCollection 2019 Nov 14.


The Multi-Modal Effect of the Anti-fibrotic Drug Pirfenidone on NSCLC.

Marwitz S, Turkowski K, Nitschkowski D, Weigert A, Brandenburg J, Reiling N, Thomas M, Reck M, Drömann D, Seeger W, Rabe KF, Savai R, Goldmann T.

Front Oncol. 2020 Jan 21;9:1550. doi: 10.3389/fonc.2019.01550. eCollection 2019.


Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Improves Lung Function versus Monotherapies in GOLD Category A Patients with COPD: Pooled Data from the Phase III PINNACLE Studies.

Martinez FJ, Rabe KF, Lipworth BJ, Arora S, Jenkins M, Martin UJ, Reisner C.

Int J Chron Obstruct Pulmon Dis. 2020 Jan 9;15:99-106. doi: 10.2147/COPD.S229794. eCollection 2020.


Dupilumab improves lung function in patients with uncontrolled, moderate-to-severe asthma.

Castro M, Rabe KF, Corren J, Pavord ID, Katelaris CH, Tohda Y, Zhang B, Rice MS, Maroni J, Rowe P, Pirozzi G, Amin N, Ruddy M, Akinlade B, Graham NMH, Teper A.

ERJ Open Res. 2020 Jan 27;6(1). pii: 00204-2019. doi: 10.1183/23120541.00204-2019. eCollection 2020 Jan.


The role of 18F-FDG-PET in detecting Richter's transformation of chronic lymphocytic leukemia in patients receiving therapy with a B-cell receptor inhibitor.

Wang Y, Rabe KG, Bold MS, Shi M, Hanson CA, Schwager SM, Call TG, Kenderian SS, Muchtar E, Hayman SR, Koehler AB, Fonder AL, Chanan-Khan AA, Van Dyke DL, Slager SL, Kay NE, Ding W, Leis JF, Parikh SA.

Haematologica. 2020 Jan 23. pii: haematol.2019.240564. doi: 10.3324/haematol.2019.240564. [Epub ahead of print] No abstract available.


Long-Term Safety and Efficacy of Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Japanese Patients with COPD.

Ichinose M, Fukushima Y, Inoue Y, Hataji O, Ferguson GT, Rabe KF, Hayashi N, Okada H, Takikawa M, Bourne E, Ballal S, DeAngelis K, Aurivillius M, Reisner C, Dorinsky P.

Int J Chron Obstruct Pulmon Dis. 2019 Dec 23;14:2993-3002. doi: 10.2147/COPD.S220861. eCollection 2019.


Efficacy and Safety of Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Japanese Patients with COPD: A Subgroup Analysis of the KRONOS Study.

Ichinose M, Fukushima Y, Inoue Y, Hataji O, Ferguson GT, Rabe KF, Hayashi N, Okada H, Takikawa M, Bourne E, Ballal S, DeAngelis K, Aurivillius M, Dorinsky P, Reisner C.

Int J Chron Obstruct Pulmon Dis. 2019 Dec 23;14:2979-2991. doi: 10.2147/COPD.S220850. eCollection 2019.


The Relationship of Three-Dimensional Joint Space Width on Weight Bearing CT With Pain and Physical Function.

Kothari MD, Rabe KG, Anderson DD, Nevitt MC, Lynch JA, Segal NA, Franz H; Multicenter Osteoarthritis Study Group.

J Orthop Res. 2019 Dec 16. doi: 10.1002/jor.24566. [Epub ahead of print]


High-sensitivity troponin I and all-cause mortality in patients with stable COPD: an analysis of the COSYCONET study.

Waschki B, Alter P, Zeller T, Magnussen C, Neumann JT, Twerenbold R, Sinning C, Herr C, Kahnert K, Fähndrich S, Blankenberg S, Rabe KF, Welte T, Jörres RA, Vogelmeier CF, Bals R, Watz H; German COSYCONET Cohort.

Eur Respir J. 2020 Feb 27;55(2). pii: 1901314. doi: 10.1183/13993003.01314-2019. Print 2020 Feb.


Carbon-nanotube reinforcement of DNA-silica nanocomposites yields programmable and cell-instructive biocoatings.

Hu Y, Domínguez CM, Bauer J, Weigel S, Schipperges A, Oelschlaeger C, Willenbacher N, Keppler S, Bastmeyer M, Heißler S, Wöll C, Scharnweber T, Rabe KS, Niemeyer CM.

Nat Commun. 2019 Dec 4;10(1):5522. doi: 10.1038/s41467-019-13381-1.


Addition of venetoclax at time of progression in ibrutinib-treated patients with chronic lymphocytic leukemia: Combination therapy to prevent ibrutinib flare.

Hampel PJ, Call TG, Ding W, Muchtar E, Kenderian SS, Wang Y, Leis JF, Witzig TE, Koehler AB, Fonder AL, Schwager SM, Rabe KG, Van Dyke DL, Braggio E, Slager SL, Kay NE, Parikh SA.

Am J Hematol. 2020 Mar;95(3):E57-E60. doi: 10.1002/ajh.25690. Epub 2019 Dec 13. No abstract available.


Electricity generation in fuel cell with light and without light and decomposition of tetracycline hydrochloride using g-C3N4/Fe0(1%)/TiO2 anode and WO3 cathode.

Rabé K, Liu L, Nahyoon NA.

Chemosphere. 2020 Mar;243:125425. doi: 10.1016/j.chemosphere.2019.125425. Epub 2019 Nov 21.


A Phenolic Acid Decarboxylase-Based All-Enzyme Hydrogel for Flow Reactor Technology.

Mittmann E, Gallus S, Bitterwolf P, Oelschlaeger C, Willenbacher N, Niemeyer CM, Rabe KS.

Micromachines (Basel). 2019 Nov 20;10(12). pii: E795. doi: 10.3390/mi10120795.


Imine Reductase Based All-Enzyme Hydrogel with Intrinsic Cofactor Regeneration for Flow Biocatalysis.

Bitterwolf P, Ott F, Rabe KS, Niemeyer CM.

Micromachines (Basel). 2019 Nov 15;10(11). pii: E783. doi: 10.3390/mi10110783.


Live and let die: epigenetic modifications of Survivin and Regucalcin in non-small cell lung cancer tissues contribute to malignancy.

Nitschkowski D, Marwitz S, Kotanidou SA, Reck M, Kugler C, Rabe KF, Ammerpohl O, Goldmann T.

Clin Epigenetics. 2019 Nov 12;11(1):157. doi: 10.1186/s13148-019-0770-6.


Superlattice-induced ferroelectricity in charge-ordered La1/3Sr2/3FeO3.

Park SY, Rabe KM, Neaton JB.

Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):23972-23976. doi: 10.1073/pnas.1906513116. Epub 2019 Nov 11.


Interobserver variability in breast carcinoma grading results in prognostic stage differences.

Rabe K, Snir OL, Bossuyt V, Harigopal M, Celli R, Reisenbichler ES.

Hum Pathol. 2019 Dec;94:51-57. doi: 10.1016/j.humpath.2019.09.006. Epub 2019 Oct 23.


Bottom-Up Assembly of DNA-Silica Nanocomposites into Micrometer-Sized Hollow Spheres.

Hu Y, Grösche M, Sheshachala S, Oelschlaeger C, Willenbacher N, Rabe KS, Niemeyer CM.

Angew Chem Int Ed Engl. 2019 Nov 25;58(48):17269-17272. doi: 10.1002/anie.201910606. Epub 2019 Oct 18.


3D-Printed Phenacrylate Decarboxylase Flow Reactors for the Chemoenzymatic Synthesis of 4-Hydroxystilbene.

Peng M, Mittmann E, Wenger L, Hubbuch J, Engqvist MKM, Niemeyer CM, Rabe KS.

Chemistry. 2019 Oct 16. doi: 10.1002/chem.201904206. [Epub ahead of print]


Carrier localization in perovskite nickelates from oxygen vacancies.

Kotiuga M, Zhang Z, Li J, Rodolakis F, Zhou H, Sutarto R, He F, Wang Q, Sun Y, Wang Y, Aghamiri NA, Hancock SB, Rokhinson LP, Landau DP, Abate Y, Freeland JW, Comin R, Ramanathan S, Rabe KM.

Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):21992-21997. doi: 10.1073/pnas.1910490116. Epub 2019 Oct 14.


A phase III study of triple therapy with budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler 320/18/9.6 μg and 160/18/9.6 μg using co-suspension delivery technology in moderate-to-very severe COPD: The ETHOS study protocol.

Rabe KF, Martinez FJ, Ferguson GT, Wang C, Singh D, Wedzicha JA, Trivedi R, St Rose E, Ballal S, McLaren J, Darken P, Reisner C, Dorinsky P.

Respir Med. 2019 Oct - Nov;158:59-66. doi: 10.1016/j.rmed.2019.08.010. Epub 2019 Aug 22.


The Effect of Neuromuscular Electrical Stimulation During Walking on Muscle Strength and Knee Pain in Obese Women With Knee Pain: A Randomized Controlled Trial.

Matsuse H, Segal NA, Rabe KG, Shiba N.

Am J Phys Med Rehabil. 2020 Jan;99(1):56-64. doi: 10.1097/PHM.0000000000001319.


A laboratory-based scoring system predicts early treatment in Rai 0 chronic lymphocytic leukemia.

Cohen JA, Rossi FM, Zucchetto A, Bomben R, Terzi-di-Bergamo L, Rabe KG, Degan M, Steffan A, Polesel J, Santinelli E, Innocenti I, Cutrona G, D' Arena G, Pozzato G, Zaja F, Chiarenza A, Rossi D, Di Raimondo F, Laurenti L, Gentile M, Morabito F, Neri A, Ferrarini M, Fegan CD, Pepper CJ, Del Poeta G, Parikh SA, Kay NE, Gattei V.

Haematologica. 2019 Oct 3. pii: haematol.2019.228171. doi: 10.3324/haematol.2019.228171. [Epub ahead of print]


Polar and phase domain walls with conducting interfacial states in a Weyl semimetal MoTe2.

Huang FT, Joon Lim S, Singh S, Kim J, Zhang L, Kim JW, Chu MW, Rabe KM, Vanderbilt D, Cheong SW.

Nat Commun. 2019 Sep 16;10(1):4211. doi: 10.1038/s41467-019-11949-5.


Interfacial charge-transfer Mott state in iridate-nickelate superlattices.

Liu X, Kotiuga M, Kim HS, N'Diaye AT, Choi Y, Zhang Q, Cao Y, Kareev M, Wen F, Pal B, Freeland JW, Gu L, Haskel D, Shafer P, Arenholz E, Haule K, Vanderbilt D, Rabe KM, Chakhalian J.

Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19863-19868. doi: 10.1073/pnas.1907043116. Epub 2019 Sep 16.


Direct coupling analysis improves the identification of beneficial amino acid mutations for the functional thermostabilization of a delicate decarboxylase.

Peng M, Maier M, Esch J, Schug A, Rabe KS.

Biol Chem. 2019 Oct 25;400(11):1519-1527. doi: 10.1515/hsz-2019-0156.


Comparison of PD-L1 expression between paired cytologic and histologic specimens from non-small cell lung cancer patients.

Kuempers C, van der Linde LIS, Reischl M, Vogel W, Stellmacher F, Reck M, Heigener D, Rabe KF, Kirfel J, Perner S, Welker L.

Virchows Arch. 2020 Feb;476(2):261-271. doi: 10.1007/s00428-019-02632-7. Epub 2019 Aug 7.


Association of elevated serumfree light chains with chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis.

Clay-Gilmour AI, Rishi AR, Goldin LR, Greenberg-Worisek AJ, Achenbach SJ, Rabe KG, Maurer MJ, Kay NE, Shanafelt TD, Call TG, Brice Weinberg J, Camp NJ, Cerhan JR, Leis J, Norman A, Murray DL, Vincent Rajkumar S, Caporaso NE, Landgren O, McMaster ML, Slager SL, Vachon CM.

Blood Cancer J. 2019 Aug 5;9(8):59. doi: 10.1038/s41408-019-0220-x.


Gait Phase Identification During Level, Incline and Decline Ambulation Tasks Using Portable Sonomyographic Sensing.

Jahanandish MH, Rabe KG, Fey NP, Hoyt K.

IEEE Int Conf Rehabil Robot. 2019 Jun;2019:988-993. doi: 10.1109/ICORR.2019.8779534.


Dupilumab Efficacy in Uncontrolled, Moderate-to-Severe Asthma with Self-Reported Chronic Rhinosinusitis.

Maspero JF, Katelaris CH, Busse WW, Castro M, Corren J, Chipps BE, Peters AT, Pavord ID, Ford LB, Sher L, Rabe KF, Rice MS, Rowe P, Lu Y, Harel S, Jagerschmidt A, Khan AH, Kamat S, Pirozzi G, Amin N, Ruddy M, Graham NMH, Mannent LP, Teper A.

J Allergy Clin Immunol Pract. 2020 Feb;8(2):527-539.e9. doi: 10.1016/j.jaip.2019.07.016. Epub 2019 Jul 24.


Microfluidic Chips for Life Sciences-A Comparison of Low Entry Manufacturing Technologies.

Grösche M, Zoheir AE, Stegmaier J, Mikut R, Mager D, Korvink JG, Rabe KS, Niemeyer CM.

Small. 2019 Aug;15(35):e1901956. doi: 10.1002/smll.201901956. Epub 2019 Jul 15.


Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia.

Giacopelli B, Zhao Q, Ruppert AS, Agyeman A, Weigel C, Wu YZ, Gerber MM, Rabe KG, Larson MC, Lu J, Blachly JS, Rogers KA, Wierda WG, Brown JR, Rai KR, Keating M, Rassenti LZ, Kipps TJ, Zenz T, Shanafelt TD, Kay NE, Abruzzo LV, Coombes KR, Woyach JA, Byrd JC, Oakes CC.

Blood. 2019 Aug 22;134(8):688-698. doi: 10.1182/blood.2019000490. Epub 2019 Jul 10.


Machine-assisted cultivation and analysis of biofilms.

Hansen SH, Kabbeck T, Radtke CP, Krause S, Krolitzki E, Peschke T, Gasmi J, Rabe KS, Wagner M, Horn H, Hubbuch J, Gescher J, Niemeyer CM.

Sci Rep. 2019 Jun 20;9(1):8933. doi: 10.1038/s41598-019-45414-6.


Clinical characteristics and outcomes of Richter transformation: experience of 204 patients from a single center.

Wang Y, Tschautscher MA, Rabe KG, Call TG, Leis JF, Kenderian SS, Kay NE, Muchtar E, Van Dyke DL, Koehler AB, Schwager SM, Slager SL, Parikh SA, Ding W.

Haematologica. 2020 Mar;105(3):765-773. doi: 10.3324/haematol.2019.224121. Epub 2019 Jun 13.


Machine Learning Applied to Predicting Microorganism Growth Temperatures and Enzyme Catalytic Optima.

Li G, Rabe KS, Nielsen J, Engqvist MKM.

ACS Synth Biol. 2019 Jun 21;8(6):1411-1420. doi: 10.1021/acssynbio.9b00099. Epub 2019 Jun 7.


Prognostic risk score for patients with relapsed or refractory chronic lymphocytic leukaemia treated with targeted therapies or chemoimmunotherapy: a retrospective, pooled cohort study with external validations.

Soumerai JD, Ni A, Darif M, Londhe A, Xing G, Mun Y, Kay NE, Shanafelt TD, Rabe KG, Byrd JC, Chanan-Khan AA, Furman RR, Hillmen P, Jones J, Seymour JF, Sharman JP, Ferrante L, Mobasher M, Stark T, Reddy V, Dreiling LK, Bhargava P, Howes A, James DF, Zelenetz AD.

Lancet Haematol. 2019 Jul;6(7):e366-e374. doi: 10.1016/S2352-3026(19)30085-7. Epub 2019 May 17. Erratum in: Lancet Haematol. 2019 Jul;6(7):e348.


Rapid disease progression following discontinuation of ibrutinib in patients with chronic lymphocytic leukemia treated in routine clinical practice.

Hampel PJ, Ding W, Call TG, Rabe KG, Kenderian SS, Witzig TE, Muchtar E, Leis JF, Chanan-Khan AA, Koehler AB, Fonder AL, Schwager SM, Slager SL, Shanafelt TD, Kay NE, Parikh SA.

Leuk Lymphoma. 2019 Nov;60(11):2712-2719. doi: 10.1080/10428194.2019.1602268. Epub 2019 Apr 24.


Psychological Impact of Learning CDKN2A Variant Status as a Genetic Research Result.

Zhu X, Leof ER, Rabe KG, McCormick JB, Petersen GM, Radecki Breitkopf C.

Public Health Genomics. 2018;21(3-4):154-163. doi: 10.1159/000496556. Epub 2019 Apr 18.


Pancreatic cancer and melanoma related perceptions and behaviors following disclosure of CDKN2A variant status as a research result.

Leof ER, Zhu X, Rabe KG, McCormick JB, Petersen GM, Radecki Breitkopf C.

Genet Med. 2019 Nov;21(11):2468-2477. doi: 10.1038/s41436-019-0517-y. Epub 2019 Apr 17.


Safety and efficacy of the human neutrophil elastase inhibitor BAY 85-8501 for the treatment of non-cystic fibrosis bronchiectasis: A randomized controlled trial.

Watz H, Nagelschmitz J, Kirsten A, Pedersen F, van der Mey D, Schwers S, Bandel TJ, Rabe KF.

Pulm Pharmacol Ther. 2019 Jun;56:86-93. doi: 10.1016/j.pupt.2019.03.009. Epub 2019 Mar 24.


Effects of airway obstruction and hyperinflation on electrocardiographic axes in COPD.

Alter P, Watz H, Kahnert K, Rabe KF, Biertz F, Fischer R, Jung P, Graf J, Bals R, Vogelmeier CF, Jörres RA.

Respir Res. 2019 Mar 27;20(1):61. doi: 10.1186/s12931-019-1025-y.


Cryobiopsy for Interstitial Lung Disease: The Heat Is On.

Raghu G, Lederer DJ, Rabe KF.

Am J Respir Crit Care Med. 2019 May 15;199(10):1183-1184. doi: 10.1164/rccm.201903-0682ED. No abstract available.


Exploring the relevance and extent of small airways dysfunction in asthma (ATLANTIS): baseline data from a prospective cohort study.

Postma DS, Brightling C, Baldi S, Van den Berge M, Fabbri LM, Gagnatelli A, Papi A, Van der Molen T, Rabe KF, Siddiqui S, Singh D, Nicolini G, Kraft M; ATLANTIS study group.

Lancet Respir Med. 2019 May;7(5):402-416. doi: 10.1016/S2213-2600(19)30049-9. Epub 2019 Mar 12. Erratum in: Lancet Respir Med. 2019 Sep;7(9):e28.


KRAS, NRAS, and BRAF mutations are highly enriched in trisomy 12 chronic lymphocytic leukemia and are associated with shorter treatment-free survival.

Vendramini E, Bomben R, Pozzo F, Benedetti D, Bittolo T, Rossi FM, Dal Bo M, Rabe KG, Pozzato G, Zaja F, Chiarenza A, Di Raimondo F, Braggio E, Parikh SA, Kay NE, Shanafelt TD, Del Poeta G, Gattei V, Zucchetto A.

Leukemia. 2019 Aug;33(8):2111-2115. doi: 10.1038/s41375-019-0444-6. Epub 2019 Mar 14. No abstract available.


Rating sputum cell quality in clinical trials for asthma and COPD treatment.

Pedersen F, Zissler UM, Watz H, Rabe KF, Hohlfeld JM, Holz O.

Int J Chron Obstruct Pulmon Dis. 2019 Jan 8;14:195-198. doi: 10.2147/COPD.S188033. eCollection 2019. No abstract available.


Applications of Protein Engineering and Directed Evolution in Plant Research.

Engqvist MKM, Rabe KS.

Plant Physiol. 2019 Mar;179(3):907-917. doi: 10.1104/pp.18.01534. Epub 2019 Jan 9. Review. No abstract available.


Solid-Phase Synthesis and Purification of Protein-DNA Origami Nanostructures.

Burgahn T, Garrecht R, Rabe KS, Niemeyer CM.

Chemistry. 2019 Mar 7;25(14):3483-3488. doi: 10.1002/chem.201805506. Epub 2019 Jan 24.


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