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Items: 1 to 50 of 127

1.

Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer's disease pathogenesis.

Esteve P, Rueda-Carrasco J, Inés Mateo M, Martin-Bermejo MJ, Draffin J, Pereyra G, Sandonís Á, Crespo I, Moreno I, Aso E, Garcia-Esparcia P, Gomez-Tortosa E, Rábano A, Fortea J, Alcolea D, Lleo A, Heneka MT, Valpuesta JM, Esteban JA, Ferrer I, Domínguez M, Bovolenta P.

Nat Neurosci. 2019 Aug;22(8):1258-1268. doi: 10.1038/s41593-019-0432-1. Epub 2019 Jul 15.

PMID:
31308530
2.

Identification of Alzheimer's Disease Autoantibodies and Their Target Biomarkers by Phage Microarrays.

San Segundo-Acosta P, Montero-Calle A, Fuentes M, Rábano A, Villalba M, Barderas R.

J Proteome Res. 2019 Jul 5;18(7):2940-2953. doi: 10.1021/acs.jproteome.9b00258. Epub 2019 Jun 7.

PMID:
31136180
3.

Activity-Dependent Reconnection of Adult-Born Dentate Granule Cells in a Mouse Model of Frontotemporal Dementia.

Terreros-Roncal J, Flor-García M, Moreno-Jiménez EP, Pallas-Bazarra N, Rábano A, Sah N, van Praag H, Giacomini D, Schinder AF, Ávila J, Llorens-Martín M.

J Neurosci. 2019 Jul 17;39(29):5794-5815. doi: 10.1523/JNEUROSCI.2724-18.2019. Epub 2019 May 27.

PMID:
31133559
4.

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer's disease.

Moreno-Jiménez EP, Flor-García M, Terreros-Roncal J, Rábano A, Cafini F, Pallas-Bazarra N, Ávila J, Llorens-Martín M.

Nat Med. 2019 Apr;25(4):554-560. doi: 10.1038/s41591-019-0375-9. Epub 2019 Mar 25.

PMID:
30911133
5.

Seeding variability of different alpha synuclein strains in synucleinopathies.

Candelise N, Schmitz M, Llorens F, Villar-Piqué A, Cramm M, Thom T, da Silva Correia SM, da Cunha JEG, Möbius W, Outeiro TF, Álvarez VG, Banchelli M, D'Andrea C, de Angelis M, Zafar S, Rabano A, Matteini P, Zerr I.

Ann Neurol. 2019 May;85(5):691-703. doi: 10.1002/ana.25446. Epub 2019 Mar 27.

PMID:
30805957
6.

Does Seipin Play a Role in Oxidative Stress Protection and Peroxisome Biogenesis? New Insights from Human Brain Autopsies.

Sánchez-Iglesias S, Fernández-Liste A, Guillín-Amarelle C, Rábano A, Rodriguez-Cañete L, González-Méndez B, Fernández-Pombo A, Senra A, Araújo-Vilar D.

Neuroscience. 2019 Jan 1;396:119-137. doi: 10.1016/j.neuroscience.2018.11.004. Epub 2018 Nov 15.

7.

Argyrophilic grain disease presenting as behavioral frontotemporal dementia.

Gil MJ, Serrano S, Manzano MS, Cuadrado ML, Góméz E, Rábano A.

Clin Neuropathol. 2019 Jan/Feb;38(1):8-13. doi: 10.5414/NP301122.

PMID:
30415651
8.

Frontotemporal lobar degeneration: Study of a clinicopathological cohort.

Gil MJ, Manzano MS, Cuadrado ML, Fernández C, Góméz E, Matesanz C, Calero M, Rábano A.

J Clin Neurosci. 2018 Dec;58:172-180. doi: 10.1016/j.jocn.2018.10.024. Epub 2018 Oct 19.

PMID:
30348585
9.

Human and Microbial Proteins From Corpora Amylacea of Alzheimer's Disease.

Pisa D, Alonso R, Marina AI, Rábano A, Carrasco L.

Sci Rep. 2018 Jun 29;8(1):9880. doi: 10.1038/s41598-018-28231-1.

10.

Clinical, genetic and neuropathological characterization of spinocerebellar ataxia type 37.

Corral-Juan M, Serrano-Munuera C, Rábano A, Cota-González D, Segarra-Roca A, Ispierto L, Cano-Orgaz AT, Adarmes AD, Méndez-Del-Barrio C, Jesús S, Mir P, Volpini V, Alvarez-Ramo R, Sánchez I, Matilla-Dueñas A.

Brain. 2018 Jul 1;141(7):1981-1997. doi: 10.1093/brain/awy137.

PMID:
29939198
11.

Argyrophilic Grain Pathology in Frontotemporal Lobar Degeneration: Demographic, Clinical, Neuropathological, and Genetic Features.

Gil MJ, Manzano MS, Cuadrado ML, Fernández C, Góméz E, Matesanz C, Calero M, Rábano A.

J Alzheimers Dis. 2018;63(3):1109-1117. doi: 10.3233/JAD-171115.

PMID:
29758948
12.

Cerebral Microbleeds in Advanced Dementia: Clinical and Pathological Correlates.

Boyano I, Ramos A, López-Alvarez J, Mendoza-Rebolledo C, Osa-Ruiz E, Rodríguez I, Pérez A, Alfayate E, González B, Fernández L, Agüera-Ortiz L, Rábano A, Olazarán J.

Am J Alzheimers Dis Other Demen. 2018 Sep;33(6):362-372. doi: 10.1177/1533317518770783. Epub 2018 May 7.

PMID:
29734821
13.

Identification of prefrontal cortex protein alterations in Alzheimer's disease.

Garranzo-Asensio M, San Segundo-Acosta P, Martínez-Useros J, Montero-Calle A, Fernández-Aceñero MJ, Häggmark-Månberg A, Pelaez-Garcia A, Villalba M, Rabano A, Nilsson P, Barderas R.

Oncotarget. 2018 Jan 24;9(13):10847-10867. doi: 10.18632/oncotarget.24303. eCollection 2018 Feb 16.

14.

Inhibition of DREAM-ATF6 interaction delays onset of cognition deficit in a mouse model of Huntington's disease.

López-Hurtado A, Burgos DF, González P, Dopazo XM, González V, Rábano A, Mellström B, Naranjo JR.

Mol Brain. 2018 Mar 9;11(1):13. doi: 10.1186/s13041-018-0359-6.

15.

Expression of nucleotide excision repair in Alzheimer's disease is higher in brain tissue than in blood.

Jensen HLB, Lillenes MS, Rabano A, Günther CC, Riaz T, Kalayou ST, Ulstein ID, Bøhmer T, Tønjum T.

Neurosci Lett. 2018 Apr 13;672:53-58. doi: 10.1016/j.neulet.2018.02.043. Epub 2018 Feb 21.

16.

Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons.

Rodriguez-Rodriguez P, Sandebring-Matton A, Merino-Serrais P, Parrado-Fernandez C, Rabano A, Winblad B, Ávila J, Ferrer I, Cedazo-Minguez A.

Brain. 2017 Dec 1;140(12):3269-3285. doi: 10.1093/brain/awx256. Erratum in: Brain. 2018 May 1;141(5):e43.

PMID:
29053786
17.

Analysis of known amyotrophic lateral sclerosis and frontotemporal dementia genes reveals a substantial genetic burden in patients manifesting both diseases not carrying the C9orf72 expansion mutation.

Dols-Icardo O, García-Redondo A, Rojas-García R, Borrego-Hernández D, Illán-Gala I, Muñoz-Blanco JL, Rábano A, Cervera-Carles L, Juárez-Rufián A, Spataro N, De Luna N, Galán L, Cortes-Vicente E, Fortea J, Blesa R, Grau-Rivera O, Lleó A, Esteban-Pérez J, Gelpi E, Clarimón J.

J Neurol Neurosurg Psychiatry. 2018 Feb;89(2):162-168. doi: 10.1136/jnnp-2017-316820. Epub 2017 Sep 9.

PMID:
28889094
18.

Fungal infection in neural tissue of patients with amyotrophic lateral sclerosis.

Alonso R, Pisa D, Fernández-Fernández AM, Rábano A, Carrasco L.

Neurobiol Dis. 2017 Dec;108:249-260. doi: 10.1016/j.nbd.2017.09.001. Epub 2017 Sep 6.

PMID:
28888971
19.

Similarities of Variant Creutzfeldt-Jakob Disease Strain in Mother and Son in Spain to UK Reference Case.

Diack AB, Boyle A, Ritchie D, Plinston C, Kisielewski D, de Pedro-Cuesta J, Rábano A, Will RG, Manson JC.

Emerg Infect Dis. 2017 Sep;23(9):1593-1596. doi: 10.3201/eid2309.170159.

20.

Absence of CX3CR1 impairs the internalization of Tau by microglia.

Bolós M, Llorens-Martín M, Perea JR, Jurado-Arjona J, Rábano A, Hernández F, Avila J.

Mol Neurodegener. 2017 Aug 15;12(1):59. doi: 10.1186/s13024-017-0200-1.

21.

Polymicrobial Infections In Brain Tissue From Alzheimer's Disease Patients.

Pisa D, Alonso R, Fernández-Fernández AM, Rábano A, Carrasco L.

Sci Rep. 2017 Jul 17;7(1):5559. doi: 10.1038/s41598-017-05903-y.

22.

Early diagnosis of mild cognitive impairment and Alzheimer's disease based on salivary lactoferrin.

Carro E, Bartolomé F, Bermejo-Pareja F, Villarejo-Galende A, Molina JA, Ortiz P, Calero M, Rabano A, Cantero JL, Orive G.

Alzheimers Dement (Amst). 2017 May 26;8:131-138. doi: 10.1016/j.dadm.2017.04.002. eCollection 2017.

23.

Neuronal tetraploidization in the cerebral cortex correlates with reduced cognition in mice and precedes and recapitulates Alzheimer's-associated neuropathology.

López-Sánchez N, Fontán-Lozano Á, Pallé A, González-Álvarez V, Rábano A, Trejo JL, Frade JM.

Neurobiol Aging. 2017 Aug;56:50-66. doi: 10.1016/j.neurobiolaging.2017.04.008. Epub 2017 Apr 18.

PMID:
28494436
24.

Fungal Enolase, β-Tubulin, and Chitin Are Detected in Brain Tissue from Alzheimer's Disease Patients.

Pisa D, Alonso R, Rábano A, Horst MN, Carrasco L.

Front Microbiol. 2016 Nov 7;7:1772. eCollection 2016.

25.

Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease.

Pérez-Cañamás A, Benvegnù S, Rueda CB, Rábano A, Satrústegui J, Ledesma MD.

Mol Psychiatry. 2017 May;22(5):711-723. doi: 10.1038/mp.2016.148. Epub 2016 Sep 13.

PMID:
27620840
26.

Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes.

Pajares M, Jiménez-Moreno N, García-Yagüe ÁJ, Escoll M, de Ceballos ML, Van Leuven F, Rábano A, Yamamoto M, Rojo AI, Cuadrado A.

Autophagy. 2016 Oct 2;12(10):1902-1916. Epub 2016 Jul 18.

27.

Etiologic Framework for the Study of Neurodegenerative Disorders as Well as Vascular and Metabolic Comorbidities on the Grounds of Shared Epidemiologic and Biologic Features.

de Pedro-Cuesta J, Martínez-Martín P, Rábano A, Ruiz-Tovar M, Alcalde-Cabero E, Calero M.

Front Aging Neurosci. 2016 Jun 13;8:138. doi: 10.3389/fnagi.2016.00138. eCollection 2016.

28.

Tau-positive nuclear indentations in P301S tauopathy mice.

Fernández-Nogales M, Santos-Galindo M, Merchán-Rubira J, Hoozemans JJM, Rábano A, Ferrer I, Avila J, Hernández F, Lucas JJ.

Brain Pathol. 2017 May;27(3):314-322. doi: 10.1111/bpa.12407. Epub 2016 Aug 2.

PMID:
27338164
29.

Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease.

Lillenes MS, Rabano A, Støen M, Riaz T, Misaghian D, Møllersen L, Esbensen Y, Günther CC, Selnes P, Stenset VT, Fladby T, Tønjum T.

Mol Brain. 2016 May 28;9(1):61. doi: 10.1186/s13041-016-0237-z.

30.

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia.

Williams KL, Topp S, Yang S, Smith B, Fifita JA, Warraich ST, Zhang KY, Farrawell N, Vance C, Hu X, Chesi A, Leblond CS, Lee A, Rayner SL, Sundaramoorthy V, Dobson-Stone C, Molloy MP, van Blitterswijk M, Dickson DW, Petersen RC, Graff-Radford NR, Boeve BF, Murray ME, Pottier C, Don E, Winnick C, McCann EP, Hogan A, Daoud H, Levert A, Dion PA, Mitsui J, Ishiura H, Takahashi Y, Goto J, Kost J, Gellera C, Gkazi AS, Miller J, Stockton J, Brooks WS, Boundy K, Polak M, Muñoz-Blanco JL, Esteban-Pérez J, Rábano A, Hardiman O, Morrison KE, Ticozzi N, Silani V, de Belleroche J, Glass JD, Kwok JB, Guillemin GJ, Chung RS, Tsuji S, Brown RH Jr, García-Redondo A, Rademakers R, Landers JE, Gitler AD, Rouleau GA, Cole NJ, Yerbury JJ, Atkin JD, Shaw CE, Nicholson GA, Blair IP.

Nat Commun. 2016 Apr 15;7:11253. doi: 10.1038/ncomms11253.

31.

Corpora Amylacea of Brain Tissue from Neurodegenerative Diseases Are Stained with Specific Antifungal Antibodies.

Pisa D, Alonso R, Rábano A, Carrasco L.

Front Neurosci. 2016 Mar 8;10:86. doi: 10.3389/fnins.2016.00086. eCollection 2016.

32.

Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's Disease.

Lastres-Becker I, García-Yagüe AJ, Scannevin RH, Casarejos MJ, Kügler S, Rábano A, Cuadrado A.

Antioxid Redox Signal. 2016 Jul 10;25(2):61-77. doi: 10.1089/ars.2015.6549. Epub 2016 Apr 27.

33.

Drivers: A Biologically Contextualized, Cross-Inferential View of the Epidemiology of Neurodegenerative Disorders.

de Pedro-Cuesta J, Martínez-Martín P, Rábano A, Alcalde-Cabero E, José García López F, Almazán-Isla J, Ruiz-Tovar M, Medrano MJ, Avellanal F, Calero O, Calero M.

J Alzheimers Dis. 2016;51(4):1003-22. doi: 10.3233/JAD-150884.

34.

The Ever-Changing Morphology of Hippocampal Granule Neurons in Physiology and Pathology.

Llorens-Martín M, Rábano A, Ávila J.

Front Neurosci. 2016 Jan 19;9:526. doi: 10.3389/fnins.2015.00526. eCollection 2015.

35.

Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns.

Sanchez-Mut JV, Heyn H, Vidal E, Moran S, Sayols S, Delgado-Morales R, Schultz MD, Ansoleaga B, Garcia-Esparcia P, Pons-Espinal M, de Lagran MM, Dopazo J, Rabano A, Avila J, Dierssen M, Lott I, Ferrer I, Ecker JR, Esteller M.

Transl Psychiatry. 2016 Jan 19;6:e718. doi: 10.1038/tp.2015.214.

36.

Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease.

Naranjo JR, Zhang H, Villar D, González P, Dopazo XM, Morón-Oset J, Higueras E, Oliveros JC, Arrabal MD, Prieto A, Cercós P, González T, De la Cruz A, Casado-Vela J, Rábano A, Valenzuela C, Gutierrez-Rodriguez M, Li JY, Mellström B.

J Clin Invest. 2016 Feb;126(2):627-38. doi: 10.1172/JCI82670. Epub 2016 Jan 11.

37.

HNK-1 Carrier Glycoproteins Are Decreased in the Alzheimer's Disease Brain.

García-Ayllón MS, Botella-López A, Cuchillo-Ibañez I, Rábano A, Andreasen N, Blennow K, Ávila J, Sáez-Valero J.

Mol Neurobiol. 2017 Jan;54(1):188-199. doi: 10.1007/s12035-015-9644-x. Epub 2016 Jan 6.

PMID:
26738850
38.

Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo.

Bolós M, Llorens-Martín M, Jurado-Arjona J, Hernández F, Rábano A, Avila J.

J Alzheimers Dis. 2016;50(1):77-87. doi: 10.3233/JAD-150704.

39.

Different Brain Regions are Infected with Fungi in Alzheimer's Disease.

Pisa D, Alonso R, Rábano A, Rodal I, Carrasco L.

Sci Rep. 2015 Oct 15;5:15015. doi: 10.1038/srep15015.

40.

MAPT H1 Haplotype is Associated with Late-Onset Alzheimer's Disease Risk in APOEɛ4 Noncarriers: Results from the Dementia Genetics Spanish Consortium.

Pastor P, Moreno F, Clarimón J, Ruiz A, Combarros O, Calero M, López de Munain A, Bullido MJ, de Pancorbo MM, Carro E, Antonell A, Coto E, Ortega-Cubero S, Hernandez I, Tárraga L, Boada M, Lleó A, Dols-Icardo O, Kulisevsky J, Vázquez-Higuera JL, Infante J, Rábano A, Fernández-Blázquez MÁ, Valentí M, Indakoetxea B, Barandiarán M, Gorostidi A, Frank-García A, Sastre I, Lorenzo E, Pastor MA, Elcoroaristizabal X, Lennarz M, Maier W, Rámirez A, Serrano-Ríos M, Lee SE, Sánchez-Juan P; Dementia Genetic Spanish Consortium (DEGESCO).

J Alzheimers Dis. 2016;49(2):343-52. doi: 10.3233/JAD-150555.

41.

Correction: Comparative Incidence of Conformational, Neurodegenerative Disorders.

de Pedro-Cuesta J, Rábano A, Martínez-Martín P, Ruiz-Tovar M, Alcalde-Cabero E, Almazán-Isla J, Avellanal F, Calero M.

PLoS One. 2015 Oct 6;10(10):e0140304. doi: 10.1371/journal.pone.0140304. eCollection 2015. No abstract available.

42.

Cerebrospinal Fluid from Alzheimer's Disease Patients Contains Fungal Proteins and DNA.

Alonso R, Pisa D, Rábano A, Rodal I, Carrasco L.

J Alzheimers Dis. 2015;47(4):873-6. doi: 10.3233/JAD-150382.

43.

Comparative Incidence of Conformational, Neurodegenerative Disorders.

de Pedro-Cuesta J, Rábano A, Martínez-Martín P, Ruiz-Tovar M, Alcalde-Cabero E, Almazán-Isla J, Avellanal F, Calero M.

PLoS One. 2015 Sep 3;10(9):e0137342. doi: 10.1371/journal.pone.0137342. eCollection 2015. Erratum in: PLoS One. 2015;10(10):e0140304.

44.

Larger aggregates of mutant seipin in Celia's Encephalopathy, a new protein misfolding neurodegenerative disease.

Ruiz-Riquelme A, Sánchez-Iglesias S, Rábano A, Guillén-Navarro E, Domingo-Jiménez R, Ramos A, Rosa I, Senra A, Nilsson P, García Á, Araújo-Vilar D, Requena JR.

Neurobiol Dis. 2015 Nov;83:44-53. doi: 10.1016/j.nbd.2015.08.006. Epub 2015 Aug 15.

PMID:
26282322
45.

Protocols for Monitoring the Development of Tau Pathology in Alzheimer's Disease.

Rábano A, Cuadros R, Merino-Serráis P, Rodal I, Benavides-Piccione R, Gómez E, Medina M, DeFelipe J, Avila J.

Methods Mol Biol. 2016;1303:143-60. doi: 10.1007/978-1-4939-2627-5_7.

PMID:
26235064
46.

Evidence for fungal infection in cerebrospinal fluid and brain tissue from patients with amyotrophic lateral sclerosis.

Alonso R, Pisa D, Marina AI, Morato E, Rábano A, Rodal I, Carrasco L.

Int J Biol Sci. 2015 Apr 2;11(5):546-58. doi: 10.7150/ijbs.11084. eCollection 2015.

47.

Super-Resolution Microscopy of Cerebrospinal Fluid Biomarkers as a Tool for Alzheimer's Disease Diagnostics.

Zhang WI, Antonios G, Rabano A, Bayer TA, Schneider A, Rizzoli SO.

J Alzheimers Dis. 2015;46(4):1007-20. doi: 10.3233/JAD-150064.

PMID:
25881910
48.

Combined Alzheimer's disease and cerebrovascular staging explains advanced dementia cognition.

Zea-Sevilla MA, Fernández-Blázquez MA, Calero M, Bermejo-Velasco P, Rábano A.

Alzheimers Dement. 2015 Nov;11(11):1358-66. doi: 10.1016/j.jalz.2015.01.004. Epub 2015 Mar 21.

PMID:
25804997
49.

A blood-based, 7-metabolite signature for the early diagnosis of Alzheimer's disease.

Olazarán J, Gil-de-Gómez L, Rodríguez-Martín A, Valentí-Soler M, Frades-Payo B, Marín-Muñoz J, Antúnez C, Frank-García A, Acedo-Jiménez C, Morlán-Gracia L, Petidier-Torregrossa R, Guisasola MC, Bermejo-Pareja F, Sánchez-Ferro Á, Pérez-Martínez DA, Manzano-Palomo S, Farquhar R, Rábano A, Calero M.

J Alzheimers Dis. 2015;45(4):1157-73. doi: 10.3233/JAD-142925.

PMID:
25649659
50.

Identification of CB₂ receptors in human nigral neurons that degenerate in Parkinson's disease.

García MC, Cinquina V, Palomo-Garo C, Rábano A, Fernández-Ruiz J.

Neurosci Lett. 2015 Feb 5;587:1-4. doi: 10.1016/j.neulet.2014.12.003. Epub 2014 Dec 3.

PMID:
25481767

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