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Items: 1 to 50 of 183

1.

Non-random mtDNA segregation patterns indicate a metastable heteroplasmic segregation unit in m.3243A>G cybrid cells.

Raap AK, Jahangir Tafrechi RS, van de Rijke FM, Pyle A, Wählby C, Szuhai K, Ravelli RB, de Coo RF, Rajasimha HK, Nilsson M, Chinnery PF, Samuels DC, Janssen GM.

PLoS One. 2012;7(12):e52080. doi: 10.1371/journal.pone.0052080. Epub 2012 Dec 18.

2.

Transient and constitutive repression of cytoplasmic translation signaling in cells with mtDNA mutation.

Janssen GM, Schwertman P, Wanga TA, Tafrechi RS, van den Broek PJ, Raap AK.

Cell Mol Life Sci. 2009 Feb;66(4):721-30. doi: 10.1007/s00018-009-8687-4.

PMID:
19137259
3.

Probe labeling and fluorescence in situ hybridization.

Wiegant J, Raap AK.

Curr Protoc Cytom. 2001 May;Chapter 8:Unit 8.3. doi: 10.1002/0471142956.cy0803s00.

PMID:
18770741
4.

Basic preparative techniques for fluorescence in situ hybridization.

Wiegant J, Raap AK.

Curr Protoc Cytom. 2001 May;Chapter 8:Unit 8.2. doi: 10.1002/0471142956.cy0802s00.

PMID:
18770740
5.

Overview of fluorescence in situ hybridization techniques for molecular cytogenetics.

Raap AK.

Curr Protoc Cytom. 2001 May;Chapter 8:Unit 8.1. doi: 10.1002/0471142956.cy0801s00.

PMID:
18770737
6.

Single-cell A3243G mitochondrial DNA mutation load assays for segregation analysis.

Jahangir Tafrechi RS, van de Rijke FM, Allallou A, Larsson C, Sloos WC, van de Sande M, Wählby C, Janssen GM, Raap AK.

J Histochem Cytochem. 2007 Nov;55(11):1159-66. Epub 2007 Aug 6.

7.

The A3243G tRNALeu(UUR) mutation induces mitochondrial dysfunction and variable disease expression without dominant negative acting translational defects in complex IV subunits at UUR codons.

Janssen GM, Hensbergen PJ, van Bussel FJ, Balog CI, Maassen JA, Deelder AM, Raap AK.

Hum Mol Genet. 2007 Oct 15;16(20):2472-81. Epub 2007 Jul 25.

PMID:
17656376
8.

COmbined Binary RAtio fluorescence in situ hybridiziation (COBRA-FISH): development and applications.

Raap AK, Tanke HJ.

Cytogenet Genome Res. 2006;114(3-4):222-6. Review.

PMID:
16954657
9.

New insights in the molecular pathogenesis of the maternally inherited diabetes and deafness syndrome.

Maassen JA, Jahangir Tafrechi RS, Janssen GM, Raap AK, Lemkes HH, 't Hart LM.

Endocrinol Metab Clin North Am. 2006 Jun;35(2):385-96, x-xi. Review.

PMID:
16632100
10.

Array-based comparative genomic hybridization analysis reveals recurrent chromosomal alterations and prognostic parameters in primary cutaneous large B-cell lymphoma.

Dijkman R, Tensen CP, Jordanova ES, Knijnenburg J, Hoefnagel JJ, Mulder AA, Rosenberg C, Raap AK, Willemze R, Szuhai K, Vermeer MH.

J Clin Oncol. 2006 Jan 10;24(2):296-305. Epub 2005 Dec 5.

PMID:
16330669
11.

Distinct nuclear gene expression profiles in cells with mtDNA depletion and homoplasmic A3243G mutation.

Jahangir Tafrechi RS, Svensson PJ, Janssen GM, Szuhai K, Maassen JA, Raap AK.

Mutat Res. 2005 Oct 15;578(1-2):43-52.

PMID:
16202796
12.

A multiplexed and miniaturized serological tuberculosis assay identifies antigens that discriminate maximally between TB and non-TB sera.

Tong M, Jacobi CE, van de Rijke FM, Kuijper S, van de Werken S, Lowary TL, Hokke CH, Appelmelk BJ, Nagelkerke NJ, Tanke HJ, van Gijlswijk RP, Veuskens J, Kolk AH, Raap AK.

J Immunol Methods. 2005 Jun;301(1-2):154-63.

PMID:
15979638
13.

In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes.

Larsson C, Koch J, Nygren A, Janssen G, Raap AK, Landegren U, Nilsson M.

Nat Methods. 2004 Dec;1(3):227-32. Epub 2004 Nov 18.

PMID:
15782198
14.

Cancer-associated mutations in chromatin remodeler hSNF5 promote chromosomal instability by compromising the mitotic checkpoint.

Vries RG, Bezrookove V, Zuijderduijn LM, Kia SK, Houweling A, Oruetxebarria I, Raap AK, Verrijzer CP.

Genes Dev. 2005 Mar 15;19(6):665-70.

15.

Complex biallelic IGH rearrangements in IgM-expressing Z-138 cell line: Involvement of downstream immunoglobulin class switch recombination.

Guikema JE, Fenton JA, de Boer C, Kleiverda K, Brink AA, Raap AK, Estrov Z, Schuuring E, Kluin PM.

Genes Chromosomes Cancer. 2005 Feb;42(2):164-9.

PMID:
15543623
16.

Positioning of cervical carcinoma and Burkitt lymphoma translocation breakpoints with respect to the human papillomavirus integration cluster in FRA8C at 8q24.13.

Ferber MJ, Eilers P, Schuuring E, Fenton JA, Fleuren GJ, Kenter G, Szuhai K, Smith DI, Raap AK, Brink AA.

Cancer Genet Cytogenet. 2004 Oct 1;154(1):1-9.

PMID:
15381365
17.

Molecular cytogenetic characterization by combined COBRA-FISH and fiber-FISH: application to PER.C6 cells.

Wiegant J, Brouwer K, Bezrookove V, Smits S, Raap AK, Bout A, Tanke HJ.

Biotechniques. 2004 Aug;37(2):188, 190, 192 passim. No abstract available.

18.

Quantitative assessment of a novel flow-through porous microarray for the rapid analysis of gene expression profiles.

Wu Y, de Kievit P, Vahlkamp L, Pijnenburg D, Smit M, Dankers M, Melchers D, Stax M, Boender PJ, Ingham C, Bastiaensen N, de Wijn R, van Alewijk D, van Damme H, Raap AK, Chan AB, van Beuningen R.

Nucleic Acids Res. 2004 Aug 27;32(15):e123.

19.

Array comparative genomic hybridization with cyanin cis-platinum-labeled DNAs.

Raap AK, van der Burg MJ, Knijnenburg J, Meershoek E, Rosenberg C, Gray JW, Wiegant J, Hodgson JG, Tanke HJ.

Biotechniques. 2004 Jul;37(1):130-4.

20.

A novel t(6;14)(q25-q27;q32) in acute myelocytic leukemia involves the BCL11B gene.

Bezrookove V, van Zelderen-Bhola SL, Brink A, Szuhai K, Raap AK, Barge R, Beverstock GC, Rosenberg C.

Cancer Genet Cytogenet. 2004 Feb;149(1):72-6.

PMID:
15104287
21.

Mitochondrial diabetes: molecular mechanisms and clinical presentation.

Maassen JA, 'T Hart LM, Van Essen E, Heine RJ, Nijpels G, Jahangir Tafrechi RS, Raap AK, Janssen GM, Lemkes HH.

Diabetes. 2004 Feb;53 Suppl 1:S103-9. Review.

22.

Fluorescence properties, thermal duplex stability, and kinetics of formation of cyanin platinum DNAs.

van de Rijke FM, Heetebrij RJ, Talman EG, Tanke HJ, Raap AK.

Anal Biochem. 2003 Oct 1;321(1):71-8.

PMID:
12963057
23.

Premature chromosome condensation revisited: a novel chemical approach permits efficient cytogenetic analysis of cancers.

Bezrookove V, Smits R, Moeslein G, Fodde R, Tanke HJ, Raap AK, Darroudi F.

Genes Chromosomes Cancer. 2003 Oct;38(2):177-86.

PMID:
12939745
24.

Comprehensive analysis of human subtelomeres with combined binary ratio labelling fluorescence in situ hybridisation.

Engels H, Ehrbrecht A, Zahn S, Bosse K, Vrolijk H, White S, Kalscheuer V, Hoovers JM, Schwanitz G, Propping P, Tanke HJ, Wiegant J, Raap AK.

Eur J Hum Genet. 2003 Sep;11(9):643-51.

25.

Platinum(II)-based coordination compounds as nucleic acid labeling reagents: synthesis, reactivity, and applications in hybridization assays.

Heetebrij RJ, Talman EG, v Velzen MA, van Gijlswijk RP, Snoeijers SS, Schalk M, Wiegant J, v d Rijke F, Kerkhoven RM, Raap AK, Tanke HJ, Reedijk J, Houthoff HJ.

Chembiochem. 2003 Jul 7;4(7):573-83.

PMID:
12851925
26.

Chemical RNA labeling without 3' end bias using fluorescent cis-platin compounds.

Hagedoorn R, Joseph R, Kasanmoentalib S, Eilers P, Killian J, Raap AK.

Biotechniques. 2003 May;34(5):974-6, 978, 980.

27.

Multicolor Fiber FISH.

Kraan J, von Bergh AR, Kleiverda K, Vaandrager JW, Jordanova ES, Raap AK, Kluin PM, Schuuring E.

Methods Mol Biol. 2002;204:143-53. Review. No abstract available.

PMID:
12397796
28.

Insights into the sites of X ray and neutron induced chromosomal aberrations in human lymphocytes using COBRA-MFISH.

Darroudi F, Bezrookove V, Fomina J, Mesker WE, Wiegant JC, Raap AK, Tanke HJ.

Radiat Prot Dosimetry. 2002;99(1-4):189-92.

PMID:
12194280
29.

Localization and regulation of the growth hormone receptor and growth hormone-binding protein in the rat growth plate.

Gevers EF, van der Eerden BC, Karperien M, Raap AK, Robinson IC, Wit JM.

J Bone Miner Res. 2002 Aug;17(8):1408-19.

30.

Real-time monitoring of rolling-circle amplification using a modified molecular beacon design.

Nilsson M, Gullberg M, Dahl F, Szuhai K, Raap AK.

Nucleic Acids Res. 2002 Jul 15;30(14):e66.

31.

Connexin 26 mutations in cases of sensorineural deafness in eastern Austria.

Frei K, Szuhai K, Lucas T, Weipoltshammer K, Schöfer C, Ramsebner R, Baumgartner WD, Raap AK, Bittner R, Wachtler FJ, Kirschhofer K.

Eur J Hum Genet. 2002 Jul;10(7):427-32.

32.
33.

A novel strategy for human papillomavirus detection and genotyping with SybrGreen and molecular beacon polymerase chain reaction.

Szuhai K, Sandhaus E, Kolkman-Uljee SM, Lemaître M, Truffert JC, Dirks RW, Tanke HJ, Fleuren GJ, Schuuring E, Raap AK.

Am J Pathol. 2001 Nov;159(5):1651-60.

34.

Linear 2' O-Methyl RNA probes for the visualization of RNA in living cells.

Molenaar C, Marras SA, Slats JC, Truffert JC, Lemaître M, Raap AK, Dirks RW, Tanke HJ.

Nucleic Acids Res. 2001 Sep 1;29(17):E89-9.

35.

Up-converting phosphor reporters for nucleic acid microarrays.

van De Rijke F, Zijlmans H, Li S, Vail T, Raap AK, Niedbala RS, Tanke HJ.

Nat Biotechnol. 2001 Mar;19(3):273-6.

PMID:
11231563
36.

Differentially painting human chromosome arms with combined binary ratio-labeling fluorescence in situ hybridization.

Wiegant J, Bezrookove V, Rosenberg C, Tanke HJ, Raap AK, Zhang H, Bittner M, Trent JM, Meltzer P.

Genome Res. 2000 Jun;10(6):861-5.

37.

Individuals with abnormal phenotype and normal G-banding karyotype: improvement and limitations in the diagnosis by the use of 24-colour FISH.

Bezrookove V, Hansson K, van der Burg M, van der Smagt JJ, Hilhorst-Hofstee Y, Wiegant J, Beverstock GC, Raap AK, Tanke H, Breuning MH, Rosenberg C.

Hum Genet. 2000 Apr;106(4):392-8.

PMID:
10830905
38.

DNA fiber-FISH staining mechanism.

van de Rijke FM, Florijn RJ, Tanke HJ, Raap AK.

J Histochem Cytochem. 2000 Jun;48(6):743-5.

PMID:
10820147
39.

Synthesis and purification of horseradish peroxidase-labeled oligonucleotides for tyramide-based fluorescence in situ hybridization.

van Gijlswijk RP, van de Corput MP, Bezrookove V, Wiegant J, Tanke HJ, Raap AK.

Histochem Cell Biol. 2000 Mar;113(3):175-80.

PMID:
10817671
40.

Characterization of a novel mitochondrial DNA deletion in a patient with a variant of the Pearson marrow-pancreas syndrome.

van den Ouweland JM, de Klerk JB, van de Corput MP, Dirks RW, Raap AK, Scholte HR, Huijmans JG, Hart LM, Bruining GJ, Maassen JA.

Eur J Hum Genet. 2000 Mar;8(3):195-203.

41.

Simultaneous molecular karyotyping and mapping of viral DNA integration sites by 25-color COBRA-FISH.

Szuhai K, Bezrookove V, Wiegant J, Vrolijk J, Dirks RW, Rosenberg C, Raap AK, Tanke HJ.

Genes Chromosomes Cancer. 2000 May;28(1):92-7.

PMID:
10738307
42.

ULS: a versatile method of labeling nucleic acids for FISH based on a monofunctional reaction of cisplatin derivatives with guanine moieties.

Wiegant JC, van Gijlswijk RP, Heetebrij RJ, Bezrookove V, Raap AK, Tanke HJ.

Cytogenet Cell Genet. 1999;87(1-2):47-52.

PMID:
10640810
43.

A resource of mapped human bacterial artificial chromosome clones.

Cheung VG, Dalrymple HL, Narasimhan S, Watts J, Schuler G, Raap AK, Morley M, Bruzel A.

Genome Res. 1999 Oct;9(10):989-93.

44.

Universal linkage system: an improved method for labeling archival DNA for comparative genomic hybridization.

Alers JC, Rochat J, Krijtenburg PJ, van Dekken H, Raap AK, Rosenberg C.

Genes Chromosomes Cancer. 1999 Jul;25(3):301-5.

PMID:
10379877
45.

New strategy for multi-colour fluorescence in situ hybridisation: COBRA: COmbined Binary RAtio labelling.

Tanke HJ, Wiegant J, van Gijlswijk RP, Bezrookove V, Pattenier H, Heetebrij RJ, Talman EG, Raap AK, Vrolijk J.

Eur J Hum Genet. 1999 Jan;7(1):2-11.

46.

Analysis of the monomeric alphoid sequences in the pericentromeric region of human chromosome 7.

de la Puente A, Velasco E, Pérez Jurado LA, Hernández-Chico C, van de Rijke FM, Scherer SW, Raap AK, Cruces J.

Cytogenet Cell Genet. 1998;83(3-4):176-81.

PMID:
10072574
47.

Chromosomal constitution of human spermatocytic seminomas: comparative genomic hybridization supported by conventional and interphase cytogenetics.

Rosenberg C, Mostert MC, Schut TB, van de Pol M, van Echten J, de Jong B, Raap AK, Tanke H, Oosterhuis JW, Looijenga LH.

Genes Chromosomes Cancer. 1998 Dec;23(4):286-91.

PMID:
9824200
48.

Fluorescence in situ hybridization using horseradish peroxidase-labeled oligodeoxynucleotides and tyramide signal amplification for sensitive DNA and mRNA detection.

van de Corput MP, Dirks RW, van Gijlswijk RP, van de Rijke FM, Raap AK.

Histochem Cell Biol. 1998 Oct;110(4):431-7.

PMID:
9792422
49.

Sensitive mRNA detection by fluorescence in situ hybridization using horseradish peroxidase-labeled oligodeoxynucleotides and tyramide signal amplification.

van de Corput MP, Dirks RW, van Gijlswijk RP, van Binnendijk E, Hattinger CM, de Paus RA, Landegent JE, Raap AK.

J Histochem Cytochem. 1998 Nov;46(11):1249-59.

PMID:
9774624
50.

Subnuclear localization of the active variant surface glycoprotein gene expression site in Trypanosoma brucei.

Chaves I, Zomerdijk J, Dirks-Mulder A, Dirks RW, Raap AK, Borst P.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12328-33.

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