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Impella 5.0® as bridge-to-recovery short-term mechanical circulatory support after LVAD explantation.

Osswald A, Schmack B, Goldwasser R, Kreusser MM, Raake PW, Karck M, Ruhparwar A.

J Thorac Dis. 2019 Apr;11(Suppl 6):S960-S962. doi: 10.21037/jtd.2019.04.34. No abstract available.


Results of concomitant groin-free percutaneous temporary RVAD support using a centrifugal pump with a double-lumen jugular venous cannula in LVAD patients.

Schmack B, Farag M, Kremer J, Grossekettler L, Brcic A, Raake PW, Kreusser MM, Goldwasser R, Popov AF, Mansur A, Karck M, Ruhparwar A.

J Thorac Dis. 2019 Apr;11(Suppl 6):S913-S920. doi: 10.21037/jtd.2018.11.121.


[Atrioventricular block and left ventricular wall mobility disorder in a 44-year-old female patient : A case report of a rarity with pitfalls].

Stempfl J, Schumacher F, Doering M, Wolf H, Streithoff F, Tacke J, Fahn H, Ehlermann P, Raake P, Klingel K, Elsner D, Groebner M.

Internist (Berl). 2019 May 23. doi: 10.1007/s00108-019-0608-5. [Epub ahead of print] German.


Comprehensive cardiac phenotyping in large animals: comparison of pressure-volume analysis and cardiac magnetic resonance imaging in pig post-myocardial infarction systolic heart failure.

Raake PWJ, Barthelmes J, Krautz B, Buss S, Huditz R, Schlegel P, Weber C, Stangassinger M, Haberkorn U, Katus HA, Most P, Pleger ST.

Int J Cardiovasc Imaging. 2019 Sep;35(9):1691-1699. doi: 10.1007/s10554-019-01610-z. Epub 2019 May 5.


CaMKII activation participates in doxorubicin cardiotoxicity and is attenuated by moderate GRP78 overexpression.

Tscheschner H, Meinhardt E, Schlegel P, Jungmann A, Lehmann LH, Müller OJ, Most P, Katus HA, Raake PW.

PLoS One. 2019 Apr 29;14(4):e0215992. doi: 10.1371/journal.pone.0215992. eCollection 2019.


Implementation of an intensified outpatient follow-up protocol improves outcomes in patients with ventricular assist devices.

Hamed S, Schmack B, Mueller F, Ehlermann P, Hittmann D, Ruhparwar A, Katus HA, Raake PW, Kreusser MM.

Clin Res Cardiol. 2019 Mar 16. doi: 10.1007/s00392-019-01451-9. [Epub ahead of print]


Effects of MitraClip on cognitive and psychological function in heart failure patients: the sicker the better.

Terhoeven V, Nikendei C, Cranz A, Weisbrod M, Geis N, Raake PW, Katus HA, Herzog W, Friederich HC, Schultz JH, Pleger ST.

Eur J Med Res. 2019 Feb 22;24(1):14. doi: 10.1186/s40001-019-0371-z.


Various effects of AAV9-mediated βARKct gene therapy on the heart in dystrophin-deficient (mdx) mice and δ-sarcoglycan-deficient (Sgcd-/-) mice.

Bauer R, Enns H, Jungmann A, Leuchs B, Volz C, Schinkel S, Koch WJ, Raake PW, Most P, Katus HA, Müller OJ.

Neuromuscul Disord. 2019 Mar;29(3):231-241. doi: 10.1016/j.nmd.2018.12.006. Epub 2018 Dec 20.


[Cardiomyopathy in a 22-year-old man with a long history of methamphetamine abuse].

Schwab DM, Katus HA, Raake PW.

Internist (Berl). 2019 Mar;60(3):304-308. doi: 10.1007/s00108-019-0559-x. Review. German.


Temporary oral anticoagulation after MitraClip - a strategy to lower the incidence of post-procedural stroke?

Geis N, Raake P, Kiriakou C, Mereles D, Frankenstein L, Abu-Sharar H, Chorianopoulos E, Katus HA, Bekeredjian R, Pleger ST.

Acta Cardiol. 2019 Jan 16:1-7. doi: 10.1080/00015385.2018.1550886. [Epub ahead of print]


Transfemoral aortic valve replacement for severe aortic valve regurgitation in a patient with a pulsatile-flow biventricular assist device.

Gomes B, Bekeredjian R, Leuschner F, Ehlermann P, Schmack B, Ruhparwar A, Raake PW, Katus HA, Kreusser MM.

ESC Heart Fail. 2019 Feb;6(1):217-221. doi: 10.1002/ehf2.12384. Epub 2018 Nov 27.


Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction.

Kaye DM, Petrie MC, McKenzie S, Hasenfuβ G, Malek F, Post M, Doughty RN, Trochu JN, Gustafsson F, Lang I, Kolodziej A, Westenfeld R, Penicka M, Rosenberg M, Hausleiter J, Raake P, Jondeau G, Bergmann MW, Spelman T, Aytug H, Ponikowski P, Hayward C; REDUCE LAP-HF study investigators.

ESC Heart Fail. 2019 Feb;6(1):62-69. doi: 10.1002/ehf2.12350. Epub 2018 Oct 11.


Transient elevation of high-sensitive troponin T after Cardioband implantation.

Kreusser MM, Pleger ST, Abu Sharar H, Geis NA, Bekeredjian R, Katus HA, Raake PW.

Herz. 2018 Sep 25. doi: 10.1007/s00059-018-4754-7. [Epub ahead of print]


Invasive hemodynamics and cardiac biomarkers to predict outcomes after percutaneous edge-to-edge mitral valve repair in patients with severe heart failure.

Kreusser MM, Geis NA, Berlin N, Greiner S, Pleger ST, Bekeredjian R, Katus HA, Raake PW.

Clin Res Cardiol. 2019 Apr;108(4):375-387. doi: 10.1007/s00392-018-1365-5. Epub 2018 Sep 6.


Haemodynamic effects of percutaneous mitral valve edge-to-edge repair in patients with end-stage heart failure awaiting heart transplantation.

Geis NA, Pleger ST, Bekeredjian R, Chorianopoulos E, Kreusser MM, Frankenstein L, Ruhparwar A, Katus HA, Raake PWJ.

ESC Heart Fail. 2018 Oct;5(5):892-901. doi: 10.1002/ehf2.12313. Epub 2018 Jul 30.


The need for dedicated advanced heart failure units to optimize heart failure care: impact of optimized advanced heart failure unit care on heart transplant outcome in high-risk patients.

Kreusser MM, Tschierschke R, Beckendorf J, Baxmann T, Frankenstein L, Dösch AO, Schultz JH, Giannitsis E, Pleger ST, Ruhparwar A, Karck M, Katus HA, Raake PW.

ESC Heart Fail. 2018 Dec;5(6):1108-1117. doi: 10.1002/ehf2.12314. Epub 2018 Jul 9.


Heart re-transplantation in Eurotransplant.

Smits JM, De Pauw M, Schulz U, Van Cleemput J, Raake P, Knezevic I, Caliskan K, Sutlic Z, Knosalla C, Schoenrath F, Szabolcs Z, Gottlieb J, Hagl C, Doesch A, Baric D, Rudez I, Strelniece A, De Vries E, Green D, Samuel U, Milicic D, Hartyanszky I, Berchtold-Herz M, Schulze PC, Mohr F, Meiser B, Haverich A, Reichenspurner H, Gummert J, Laufer G, Zuckermann A.

Transpl Int. 2018 Nov;31(11):1223-1232. doi: 10.1111/tri.13289. Epub 2018 Jul 16.


Prognostic relevance of hemodialysis for short-term survival in patients after LVAD implantation.

Schmack B, Grossekettler L, Weymann A, Schamroth J, Sabashnikov A, Raake PW, Popov AF, Mansur A, Karck M, Schwenger V, Ruhparwar A.

Sci Rep. 2018 Jun 4;8(1):8546. doi: 10.1038/s41598-018-26515-0.


Competing Flow Between Partial Circulatory Support and Native Cardiac Output: A Clinical Computational Fluid Dynamics Study.

Engelke J, Karmonik C, Rengier F, Partovi S, Popov AF, Osswald A, Arif R, Schmack B, Raake P, Simon AR, Doesch A, Weymann A, Lotz J, Karck M, Ruhparwar A.

ASAIO J. 2018 Sep/Oct;64(5):636-642. doi: 10.1097/MAT.0000000000000701.


Successful support of biventricular heart failure patients by new EXCOR® Adult pumps with bileaflet valves: a prospective study.

Schmack B, Weymann A, Ruschitzka F, Autschbach R, Raake PW, Jurrmann N, Menon AK, Karck M, Wilhelm MJ, Ruhparwar A.

Clin Res Cardiol. 2018 May;107(5):413-420. doi: 10.1007/s00392-017-1200-4. Epub 2018 Jan 2.


Improved outcomes after heart transplantation for cardiac amyloidosis in the modern era.

Kristen AV, Kreusser MM, Blum P, Schönland SO, Frankenstein L, Dösch AO, Knop B, Helmschrott M, Schmack B, Ruhparwar A, Hegenbart U, Katus HA, Raake PWJ.

J Heart Lung Transplant. 2018 May;37(5):611-618. doi: 10.1016/j.healun.2017.11.015. Epub 2017 Nov 15.


Percutaneous repair of mitral valve regurgitation in patients with severe heart failure: comparison with optimal medical treatment.

Geis N, Raake P, Lewening M, Mereles D, Chorianopoulos E, Frankenstein L, Katus HA, Bekeredjian R, Pleger ST.

Acta Cardiol. 2018 Aug;73(4):378-386. doi: 10.1080/00015385.2017.1401275. Epub 2017 Nov 21.


Percutaneous repair of severe mitral valve regurgitation secondary to chordae rupture in octogenarians using MitraClip.

Geis N, Raake P, Mereles D, Chorianopoulos E, Szabo G, Katus HA, Bekeredjian R, Pleger ST.

J Interv Cardiol. 2018 Feb;31(1):76-82. doi: 10.1111/joic.12455. Epub 2017 Oct 12.


Extracorporeal life support with left ventricular decompression-improved survival in severe cardiogenic shock: results from a retrospective study.

Schmack B, Seppelt P, Weymann A, Alt C, Farag M, Arif R, Doesch AO, Raake PW, Kallenbach K, Mansur A, Popov AF, Karck M, Ruhparwar A.

PeerJ. 2017 Sep 29;5:e3813. doi: 10.7717/peerj.3813. eCollection 2017.


G protein-coupled receptor kinase 2 promotes cardiac hypertrophy.

Schlegel P, Reinkober J, Meinhardt E, Tscheschner H, Gao E, Schumacher SM, Yuan A, Backs J, Most P, Wieland T, Koch WJ, Katus HA, Raake PW.

PLoS One. 2017 Jul 31;12(7):e0182110. doi: 10.1371/journal.pone.0182110. eCollection 2017.


Central Extracorporeal Life Support With Left Ventricular Decompression to Berlin Heart Excor: A Reliable "Bridge to Bridge" Strategy in Crash and Burn Patients.

Weymann A, Farag M, Sabashnikov A, Fatullayev J, Zeriouh M, Schmack B, Arif R, Müller F, Alt C, Raake P, Prakash Patil N, Popov AF, Rüdiger Simon A, Karck M, Ruhparwar A; Heidelberg-Cologne-Harefield Cardiothoracic Transplantation & Mechanical Circulatory Support Outcomes Research Group.

Artif Organs. 2017 Jun;41(6):519-528. doi: 10.1111/aor.12792. Epub 2016 Nov 8.


One-Year Outcomes After Transcatheter Insertion of an Interatrial Shunt Device for the Management of Heart Failure With Preserved Ejection Fraction.

Kaye DM, Hasenfuß G, Neuzil P, Post MC, Doughty R, Trochu JN, Kolodziej A, Westenfeld R, Penicka M, Rosenberg M, Walton A, Muller D, Walters D, Hausleiter J, Raake P, Petrie MC, Bergmann M, Jondeau G, Feldman T, Veldhuisen DJ, Ponikowski P, Silvestry FE, Burkhoff D, Hayward C.

Circ Heart Fail. 2016 Dec;9(12). pii: e003662.


Locally Targeted Cardiac Gene Delivery by AAV Microbubble Destruction in a Large Animal Model.

Schlegel P, Huditz R, Meinhardt E, Rapti K, Geis N, Most P, Katus HA, Müller OJ, Bekeredjian R, Raake PW.

Hum Gene Ther Methods. 2016 Apr;27(2):71-8. doi: 10.1089/hgtb.2015.120.


Long-term outcome of patients with and without super-response to CRT-D.

Franke J, Keppler J, Abadei AK, Bajrovic A, Meme L, Zugck C, Raake PW, Zitron E, Katus HA, Frankenstein L.

Clin Res Cardiol. 2016 Apr;105(4):341-8. doi: 10.1007/s00392-015-0926-0. Epub 2015 Oct 23.


Prediction of functional recovery by cardiac magnetic resonance feature tracking imaging in first time ST-elevation myocardial infarction. Comparison to infarct size and transmurality by late gadolinium enhancement.

Buss SJ, Krautz B, Hofmann N, Sander Y, Rust L, Giusca S, Galuschky C, Seitz S, Giannitsis E, Pleger S, Raake P, Most P, Katus HA, Korosoglou G.

Int J Cardiol. 2015 Mar 15;183:162-70. doi: 10.1016/j.ijcard.2015.01.022. Epub 2015 Jan 7.


Rescue renal sympathetic denervation in a patient with ventricular electrical storm refractory to endo- and epicardial catheter ablation: response to comments by Huang et al.

Scholz EP, Raake P, Thomas D, Vogel B, Katus HA, Blessing E.

Clin Res Cardiol. 2015 Feb;104(2):194-5. doi: 10.1007/s00392-014-0769-0. Epub 2014 Oct 15. No abstract available.


Rescue renal sympathetic denervation in a patient with ventricular electrical storm refractory to endo- and epicardial catheter ablation.

Scholz EP, Raake P, Thomas D, Vogel B, Katus HA, Blessing E.

Clin Res Cardiol. 2015 Jan;104(1):79-84. doi: 10.1007/s00392-014-0749-4. Epub 2014 Aug 7. No abstract available.


Central extracorporeal life support with left ventricular decompression for the treatment of refractory cardiogenic shock and lung failure.

Weymann A, Schmack B, Sabashnikov A, Bowles CT, Raake P, Arif R, Verch M, Tochtermann U, Roggenbach J, Popov AF, Simon AR, Karck M, Ruhparwar A.

J Cardiothorac Surg. 2014 Mar 29;9:60. doi: 10.1186/1749-8090-9-60.


Cardiac calcium handling on trial: targeting the failing cardiomyocyte signalosome.

Pleger ST, Raake P, Katus HA, Most P.

Circ Res. 2014 Jan 3;114(1):12-4. doi: 10.1161/CIRCRESAHA.113.302748. No abstract available.


Therapeutic safety of high myocardial expression levels of the molecular inotrope S100A1 in a preclinical heart failure model.

Weber C, Neacsu I, Krautz B, Schlegel P, Sauer S, Raake P, Ritterhoff J, Jungmann A, Remppis AB, Stangassinger M, Koch WJ, Katus HA, Müller OJ, Most P, Pleger ST.

Gene Ther. 2014 Feb;21(2):131-8. doi: 10.1038/gt.2013.63. Epub 2013 Dec 5.


[Advanced and terminal heart failure in the light of new guidelines and innovative treatment options].

Raake P, Pleger S, Katus HA.

Dtsch Med Wochenschr. 2013 Oct;138(40):2027-30. doi: 10.1055/s-0033-1349513. Epub 2013 Sep 24. German. No abstract available.


Heart failure gene therapy: the path to clinical practice.

Pleger ST, Brinks H, Ritterhoff J, Raake P, Koch WJ, Katus HA, Most P.

Circ Res. 2013 Aug 30;113(6):792-809. doi: 10.1161/CIRCRESAHA.113.300269. Review.


Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway.

Fan Q, Chen M, Zuo L, Shang X, Huang MZ, Ciccarelli M, Raake P, Brinks H, Chuprun KJ, Dorn GW 2nd, Koch WJ, Gao E.

PLoS One. 2013 Jun 21;8(6):e66234. doi: 10.1371/journal.pone.0066234. Print 2013.


[First "Advanced Heart Failure Unit" at the Heart Centre of the University hospital Heidelberg].

Tschierschke R, Katus HA, Raake PW.

Dtsch Med Wochenschr. 2013 Mar;138(12):603-7. doi: 10.1055/s-0032-1332996. Epub 2013 Mar 12. German. No abstract available.


[Cardiomyopathies - heart failure: new concepts].

Katus HA, Raake P, Erdmann E.

Dtsch Med Wochenschr. 2013 Mar;138(12):569. doi: 10.1055/s-0032-1332971. Epub 2013 Mar 12. German. No abstract available.


S100A1 gene therapy in small and large animals.

Most P, Raake P, Weber C, Katus HA, Pleger ST.

Methods Mol Biol. 2013;963:407-20. doi: 10.1007/978-1-62703-230-8_25.


Cardiac G-protein-coupled receptor kinase 2 ablation induces a novel Ca2+ handling phenotype resistant to adverse alterations and remodeling after myocardial infarction.

Raake PW, Zhang X, Vinge LE, Brinks H, Gao E, Jaleel N, Li Y, Tang M, Most P, Dorn GW 2nd, Houser SR, Katus HA, Chen X, Koch WJ.

Circulation. 2012 May 1;125(17):2108-18. doi: 10.1161/CIRCULATIONAHA.111.044255. Epub 2012 Apr 10.


Targeting GRK2 by gene therapy for heart failure: benefits above β-blockade.

Reinkober J, Tscheschner H, Pleger ST, Most P, Katus HA, Koch WJ, Raake PW.

Gene Ther. 2012 Jun;19(6):686-93. doi: 10.1038/gt.2012.9. Epub 2012 Feb 16. Review.


AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model.

Raake PW, Schlegel P, Ksienzyk J, Reinkober J, Barthelmes J, Schinkel S, Pleger S, Mier W, Haberkorn U, Koch WJ, Katus HA, Most P, Müller OJ.

Eur Heart J. 2013 May;34(19):1437-47. doi: 10.1093/eurheartj/ehr447. Epub 2012 Jan 19.


Gene therapy targets in heart failure: the path to translation.

Raake PW, Tscheschner H, Reinkober J, Ritterhoff J, Katus HA, Koch WJ, Most P.

Clin Pharmacol Ther. 2011 Oct;90(4):542-53. doi: 10.1038/clpt.2011.148. Epub 2011 Aug 24. Review.


Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model.

Pleger ST, Shan C, Ksienzyk J, Bekeredjian R, Boekstegers P, Hinkel R, Schinkel S, Leuchs B, Ludwig J, Qiu G, Weber C, Raake P, Koch WJ, Katus HA, Müller OJ, Most P.

Sci Transl Med. 2011 Jul 20;3(92):92ra64. doi: 10.1126/scitranslmed.3002097.


Polymorphisms present in G-protein-coupled receptor kinases and their effect on β-blocker treatment.

Raake PW, Koch WJ, Most P.

Pharmacogenomics. 2011 Mar;12(3):295-7. doi: 10.2217/pgs.11.13. No abstract available.


Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms.

Brinks H, Boucher M, Gao E, Chuprun JK, Pesant S, Raake PW, Huang ZM, Wang X, Qiu G, Gumpert A, Harris DM, Eckhart AD, Most P, Koch WJ.

Circ Res. 2010 Oct 29;107(9):1140-9. doi: 10.1161/CIRCRESAHA.110.221010. Epub 2010 Sep 2.


Dynamic changes in lymphocyte GRK2 levels in cardiac transplant patients: a biomarker for left ventricular function.

Bonita RE, Raake PW, Otis NJ, Chuprun JK, Spivack T, Dasgupta A, Whellan DJ, Mather PJ, Koch WJ.

Clin Transl Sci. 2010 Feb;3(1):14-8. doi: 10.1111/j.1752-8062.2010.00176.x.


Inhibition of angiotensin II Gq signaling augments beta-adrenergic receptor mediated effects in a renal artery stenosis model of high blood pressure.

Harris DM, Chen X, Pesant S, Cohn HI, MacDonnell SM, Boucher M, Vinge LE, Raake P, Moraca SR, Li D, Most P, Houser SR, Koch WJ, Eckhart AD.

J Mol Cell Cardiol. 2009 Jan;46(1):100-7. doi: 10.1016/j.yjmcc.2008.09.708. Epub 2008 Sep 30.

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