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Best matches for Rüttiger L[au]:

Biomarkers for Hearing Dysfunction: Facts and Outlook. Rüttiger L et al. ORL J Otorhinolaryngol Relat Spec. (2017)

Defective Gpsm2/Gα<sub>i3</sub> signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome. Mauriac SA et al. Nat Commun. (2017)

Reduced sound-evoked and resting-state BOLD fMRI connectivity in tinnitus. Hofmeier B et al. Neuroimage Clin. (2018)

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Items: 1 to 50 of 65


Differential deletion of GDNF in the auditory system leads to altered sound responsiveness.

Harasztosi C, Wolter S, Gutsche K, Durán-Alonso MB, López-Hernández I, Pascual A, López-Barneo J, Knipper M, Rüttiger L, Schimmang T.

J Neurosci Res. 2019 Oct 30. doi: 10.1002/jnr.24544. [Epub ahead of print]


Gata3 is required for the functional maturation of inner hair cells and their innervation in the mouse cochlea.

Bardhan T, Jeng JY, Waldmann M, Ceriani F, Johnson SL, Olt J, Rüttiger L, Marcotti W, Holley MC.

J Physiol. 2019 Jul;597(13):3389-3406. doi: 10.1113/JP277997. Epub 2019 May 28.


[Differentiating cochlear synaptopathies into different hearing disorders].

Knipper M, Hofmeier B, Singer W, Wolpert S, Klose U, Rüttiger L.

HNO. 2019 Jun;67(6):406-416. doi: 10.1007/s00106-019-0660-4. Review. German.


Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use.

Ishikawa M, García-Mateo N, Čusak A, López-Hernández I, Fernández-Martínez M, Müller M, Rüttiger L, Singer W, Löwenheim H, Kosec G, Fujs Š, Martínez-Martínez L, Schimmang T, Petković H, Knipper M, Durán-Alonso MB.

Sci Rep. 2019 Feb 20;9(1):2410. doi: 10.1038/s41598-019-38634-3.


Enhanced Central Neural Gain Compensates Acoustic Trauma-induced Cochlear Impairment, but Unlikely Correlates with Tinnitus and Hyperacusis.

Möhrle D, Hofmeier B, Amend M, Wolpert S, Ni K, Bing D, Klose U, Pichler B, Knipper M, Rüttiger L.

Neuroscience. 2019 May 21;407:146-169. doi: 10.1016/j.neuroscience.2018.12.038. Epub 2018 Dec 29.


BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo.

Singer W, Manthey M, Panford-Walsh R, Matt L, Geisler HS, Passeri E, Baj G, Tongiorgi E, Leal G, Duarte CB, Salazar IL, Eckert P, Rohbock K, Hu J, Strotmann J, Ruth P, Zimmermann U, Rüttiger L, Ott T, Schimmang T, Knipper M.

Front Mol Neurosci. 2018 Sep 27;11:325. doi: 10.3389/fnmol.2018.00325. eCollection 2018.


GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing.

Wolter S, Möhrle D, Schmidt H, Pfeiffer S, Zelle D, Eckert P, Krämer M, Feil R, Pilz PKD, Knipper M, Rüttiger L.

Front Neural Circuits. 2018 Aug 29;12:65. doi: 10.3389/fncir.2018.00065. eCollection 2018.


Reduced sound-evoked and resting-state BOLD fMRI connectivity in tinnitus.

Hofmeier B, Wolpert S, Aldamer ES, Walter M, Thiericke J, Braun C, Zelle D, Rüttiger L, Klose U, Knipper M.

Neuroimage Clin. 2018 Aug 31;20:637-649. doi: 10.1016/j.nicl.2018.08.029. eCollection 2018.


Visualizing BDNF Transcript Usage During Sound-Induced Memory Linked Plasticity.

Matt L, Eckert P, Panford-Walsh R, Geisler HS, Bausch AE, Manthey M, Müller NIC, Harasztosi C, Rohbock K, Ruth P, Friauf E, Ott T, Zimmermann U, Rüttiger L, Schimmang T, Knipper M, Singer W.

Front Mol Neurosci. 2018 Jul 31;11:260. doi: 10.3389/fnmol.2018.00260. eCollection 2018.


Gαi Proteins are Indispensable for Hearing.

Beer-Hammer S, Lee SC, Mauriac SA, Leiss V, Groh IAM, Novakovic A, Piekorz RP, Bucher K, Chen C, Ni K, Singer W, Harasztosi C, Schimmang T, Zimmermann U, Pfeffer K, Birnbaumer L, Forge A, Montcouquiol M, Knipper M, Nürnberg B, Rüttiger L.

Cell Physiol Biochem. 2018;47(4):1509-1532. doi: 10.1159/000490867. Epub 2018 Jun 21.


Author Correction: Defective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome.

Mauriac SA, Hien YE, Bird JE, Carvalho SD, Peyroutou R, Lee SC, Moreau MM, Blanc JM, Gezer A, Medina C, Thoumine O, Beer-Hammer S, Friedman TB, Rüttiger L, Forge A, Nürnberg B, Sans N, Montcouquiol M.

Nat Commun. 2018 May 25;9:16188. doi: 10.1038/ncomms16188.


The glucocorticoid antagonist mifepristone attenuates sound-induced long-term deficits in auditory nerve response and central auditory processing in female rats.

Singer W, Kasini K, Manthey M, Eckert P, Armbruster P, Vogt MA, Jaumann M, Dotta M, Yamahara K, Harasztosi C, Zimmermann U, Knipper M, Rüttiger L.

FASEB J. 2018 Jun;32(6):3005-3019. doi: 10.1096/fj.201701041RRR. Epub 2018 Jan 12.


NO-Sensitive Guanylate Cyclase Isoforms NO-GC1 and NO-GC2 Contribute to Noise-Induced Inner Hair Cell Synaptopathy.

Möhrle D, Reimann K, Wolter S, Wolters M, Varakina K, Mergia E, Eichert N, Geisler HS, Sandner P, Ruth P, Friebe A, Feil R, Zimmermann U, Koesling D, Knipper M, Rüttiger L.

Mol Pharmacol. 2017 Oct;92(4):375-388. doi: 10.1124/mol.117.108548.


Defective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome.

Mauriac SA, Hien YE, Bird JE, Carvalho SD, Peyroutou R, Lee SC, Moreau MM, Blanc JM, Geyser A, Medina C, Thoumine O, Beer-Hammer S, Friedman TB, Rüttiger L, Forge A, Nürnberg B, Sans N, Montcouquiol M.

Nat Commun. 2017 Apr 7;8:14907. doi: 10.1038/ncomms14907. Erratum in: Nat Commun. 2018 May 25;9:16188.


Biomarkers for Hearing Dysfunction: Facts and Outlook.

Rüttiger L, Zimmermann U, Knipper M.

ORL J Otorhinolaryngol Relat Spec. 2017;79(1-2):93-111. doi: 10.1159/000455705. Epub 2017 Feb 24. Review.


Functional Role of γ-Crystallin N in the Auditory Hindbrain.

Hartwich H, Rosengauer E, Rüttiger L, Wilms V, Waterholter SK, Nothwang HG.

PLoS One. 2016 Aug 12;11(8):e0161140. doi: 10.1371/journal.pone.0161140. eCollection 2016.


Loss of auditory sensitivity from inner hair cell synaptopathy can be centrally compensated in the young but not old brain.

Möhrle D, Ni K, Varakina K, Bing D, Lee SC, Zimmermann U, Knipper M, Rüttiger L.

Neurobiol Aging. 2016 Aug;44:173-184. doi: 10.1016/j.neurobiolaging.2016.05.001. Epub 2016 May 10.


Loss of glycine receptors containing the α3 subunit compromises auditory nerve activity, but not outer hair cell function.

Dlugaiczyk J, Hecker D, Neubert C, Buerbank S, Campanelli D, Becker CM, Betz H, Knipper M, Rüttiger L, Schick B.

Hear Res. 2016 Jul;337:25-34. doi: 10.1016/j.heares.2016.05.004. Epub 2016 May 18.


BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury.

Chumak T, Rüttiger L, Lee SC, Campanelli D, Zuccotti A, Singer W, Popelář J, Gutsche K, Geisler HS, Schraven SP, Jaumann M, Panford-Walsh R, Hu J, Schimmang T, Zimmermann U, Syka J, Knipper M.

Mol Neurobiol. 2016 Oct;53(8):5607-27. doi: 10.1007/s12035-015-9474-x. Epub 2015 Oct 17.


Absence of Early Neuronal Death in the Olivocochlear System Following Acoustic Overstimulation.

Reuss S, Closhen C, Riemann R, Jaumann M, Knipper M, Rüttiger L, Wolpert S.

Anat Rec (Hoboken). 2016 Jan;299(1):103-10. doi: 10.1002/ar.23277. Epub 2015 Oct 30.


L-type Calcium Channel Cav1.2 Is Required for Maintenance of Auditory Brainstem Nuclei.

Ebbers L, Satheesh SV, Janz K, Rüttiger L, Blosa M, Hofmann F, Morawski M, Griesemer D, Knipper M, Friauf E, Nothwang HG.

J Biol Chem. 2015 Sep 25;290(39):23692-710. doi: 10.1074/jbc.M115.672675. Epub 2015 Aug 4.


Deletion of myosin VI causes slow retinal optic neuropathy and age-related macular degeneration (AMD)-relevant retinal phenotype.

Schubert T, Gleiser C, Heiduschka P, Franz C, Nagel-Wolfrum K, Sahaboglu A, Weisschuh N, Eske G, Rohbock K, Rieger N, Paquet-Durand F, Wissinger B, Wolfrum U, Hirt B, Singer W, Rüttiger L, Zimmermann U, Knipper M.

Cell Mol Life Sci. 2015 Oct;72(20):3953-69. doi: 10.1007/s00018-015-1913-3. Epub 2015 May 6.


Cochlear NMDA receptors as a therapeutic target of noise-induced tinnitus.

Bing D, Lee SC, Campanelli D, Xiong H, Matsumoto M, Panford-Walsh R, Wolpert S, Praetorius M, Zimmermann U, Chu H, Knipper M, Rüttiger L, Singer W.

Cell Physiol Biochem. 2015;35(5):1905-23. doi: 10.1159/000374000. Epub 2015 Mar 26.


Specific synaptopathies diversify brain responses and hearing disorders: you lose the gain from early life.

Knipper M, Panford-Walsh R, Singer W, Rüttiger L, Zimmermann U.

Cell Tissue Res. 2015 Jul;361(1):77-93. doi: 10.1007/s00441-015-2168-x. Epub 2015 Apr 7. Review.


α2δ3 is essential for normal structure and function of auditory nerve synapses and is a novel candidate for auditory processing disorders.

Pirone A, Kurt S, Zuccotti A, Rüttiger L, Pilz P, Brown DH, Franz C, Schweizer M, Rust MB, Rübsamen R, Friauf E, Knipper M, Engel J.

J Neurosci. 2014 Jan 8;34(2):434-45. doi: 10.1523/JNEUROSCI.3085-13.2014.


Autonomous functions of murine thyroid hormone receptor TRα and TRβ in cochlear hair cells.

Dettling J, Franz C, Zimmermann U, Lee SC, Bress A, Brandt N, Feil R, Pfister M, Engel J, Flamant F, Rüttiger L, Knipper M.

Mol Cell Endocrinol. 2014 Jan 25;382(1):26-37. doi: 10.1016/j.mce.2013.08.025. Epub 2013 Sep 6.


Advances in the neurobiology of hearing disorders: recent developments regarding the basis of tinnitus and hyperacusis.

Knipper M, Van Dijk P, Nunes I, Rüttiger L, Zimmermann U.

Prog Neurobiol. 2013 Dec;111:17-33. doi: 10.1016/j.pneurobio.2013.08.002. Epub 2013 Sep 6. Review.


L-type CaV1.2 deletion in the cochlea but not in the brainstem reduces noise vulnerability: implication for CaV1.2-mediated control of cochlear BDNF expression.

Zuccotti A, Lee SC, Campanelli D, Singer W, Satheesh SV, Patriarchi T, Geisler HS, Köpschall I, Rohbock K, Nothwang HG, Hu J, Hell JW, Schimmang T, Rüttiger L, Knipper M.

Front Mol Neurosci. 2013 Aug 9;6:20. doi: 10.3389/fnmol.2013.00020. eCollection 2013.


Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2.

Furness DN, Johnson SL, Manor U, Rüttiger L, Tocchetti A, Offenhauser N, Olt J, Goodyear RJ, Vijayakumar S, Dai Y, Hackney CM, Franz C, Di Fiore PP, Masetto S, Jones SM, Knipper M, Holley MC, Richardson GP, Kachar B, Marcotti W.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13898-903. doi: 10.1073/pnas.1304644110. Epub 2013 Aug 5.


The reduced cochlear output and the failure to adapt the central auditory response causes tinnitus in noise exposed rats.

Rüttiger L, Singer W, Panford-Walsh R, Matsumoto M, Lee SC, Zuccotti A, Zimmermann U, Jaumann M, Rohbock K, Xiong H, Knipper M.

PLoS One. 2013;8(3):e57247. doi: 10.1371/journal.pone.0057247. Epub 2013 Mar 13.


Noise-induced inner hair cell ribbon loss disturbs central arc mobilization: a novel molecular paradigm for understanding tinnitus.

Singer W, Zuccotti A, Jaumann M, Lee SC, Panford-Walsh R, Xiong H, Zimmermann U, Franz C, Geisler HS, Köpschall I, Rohbock K, Varakina K, Verpoorten S, Reinbothe T, Schimmang T, Rüttiger L, Knipper M.

Mol Neurobiol. 2013 Feb;47(1):261-79. doi: 10.1007/s12035-012-8372-8. Epub 2012 Nov 16.


AMP-activated protein kinase in BK-channel regulation and protection against hearing loss following acoustic overstimulation.

Föller M, Jaumann M, Dettling J, Saxena A, Pakladok T, Munoz C, Ruth P, Sopjani M, Seebohm G, Rüttiger L, Knipper M, Lang F.

FASEB J. 2012 Oct;26(10):4243-53. doi: 10.1096/fj.12-208132. Epub 2012 Jul 5.


Lack of brain-derived neurotrophic factor hampers inner hair cell synapse physiology, but protects against noise-induced hearing loss.

Zuccotti A, Kuhn S, Johnson SL, Franz C, Singer W, Hecker D, Geisler HS, Köpschall I, Rohbock K, Gutsche K, Dlugaiczyk J, Schick B, Marcotti W, Rüttiger L, Schimmang T, Knipper M.

J Neurosci. 2012 Jun 20;32(25):8545-53. doi: 10.1523/JNEUROSCI.1247-12.2012.


Critical role for cochlear hair cell BK channels for coding the temporal structure and dynamic range of auditory information for central auditory processing.

Kurt S, Sausbier M, Rüttiger L, Brandt N, Moeller CK, Kindler J, Sausbier U, Zimmermann U, van Straaten H, Neuhuber W, Engel J, Knipper M, Ruth P, Schulze H.

FASEB J. 2012 Sep;26(9):3834-43. doi: 10.1096/fj.11-200535. Epub 2012 Jun 12.


Retrocochlear function of the peripheral deafness gene Cacna1d.

Satheesh SV, Kunert K, Rüttiger L, Zuccotti A, Schönig K, Friauf E, Knipper M, Bartsch D, Nothwang HG.

Hum Mol Genet. 2012 Sep 1;21(17):3896-909. doi: 10.1093/hmg/dds217. Epub 2012 Jun 7.


Loss of mammal-specific tectorial membrane component carcinoembryonic antigen cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies.

Kammerer R, Rüttiger L, Riesenberg R, Schäuble C, Krupar R, Kamp A, Sunami K, Eisenried A, Hennenberg M, Grunert F, Bress A, Battaglia S, Schrewe H, Knipper M, Schneider MR, Zimmermann W.

J Biol Chem. 2012 Jun 22;287(26):21584-98. doi: 10.1074/jbc.M111.320481. Epub 2012 Apr 27.


Altered phenotype of the vestibular organ in GLAST-1 null mice.

Schraven SP, Franz C, Rüttiger L, Löwenheim H, Lysakowski A, Stoffel W, Knipper M.

J Assoc Res Otolaryngol. 2012 Jun;13(3):323-33. doi: 10.1007/s10162-011-0311-2. Epub 2012 Feb 14.


cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function.

Jaumann M, Dettling J, Gubelt M, Zimmermann U, Gerling A, Paquet-Durand F, Feil S, Wolpert S, Franz C, Varakina K, Xiong H, Brandt N, Kuhn S, Geisler HS, Rohbock K, Ruth P, Schlossmann J, Hütter J, Sandner P, Feil R, Engel J, Knipper M, Rüttiger L.

Nat Med. 2012 Jan 22;18(2):252-9. doi: 10.1038/nm.2634.


Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells.

Zampini V, Rüttiger L, Johnson SL, Franz C, Furness DN, Waldhaus J, Xiong H, Hackney CM, Holley MC, Offenhauser N, Di Fiore PP, Knipper M, Masetto S, Marcotti W.

PLoS Biol. 2011 Apr;9(4):e1001048. doi: 10.1371/journal.pbio.1001048. Epub 2011 Apr 19.


Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses.

Johnson SL, Franz C, Kuhn S, Furness DN, Rüttiger L, Münkner S, Rivolta MN, Seward EP, Herschman HR, Engel J, Knipper M, Marcotti W.

Nat Neurosci. 2010 Jan;13(1):45-52. doi: 10.1038/nn.2456. Epub 2009 Dec 13.


Ba2+ currents in inner and outer hair cells of mice lacking the voltage-dependent Ca2+ channel subunits beta3 or beta4.

Kuhn S, Knirsch M, Rüttiger L, Kasperek S, Winter H, Freichel M, Flockerzi V, Knipper M, Engel J.

Channels (Austin). 2009 Sep-Oct;3(5):366-76. Epub 2009 Sep 17.


Deafness in TRbeta mutants is caused by malformation of the tectorial membrane.

Winter H, Rüttiger L, Müller M, Kuhn S, Brandt N, Zimmermann U, Hirt B, Bress A, Sausbier M, Conscience A, Flamant F, Tian Y, Zuo J, Pfister M, Ruth P, Löwenheim H, Samarut J, Engel J, Knipper M.

J Neurosci. 2009 Feb 25;29(8):2581-7. doi: 10.1523/JNEUROSCI.3557-08.2009.


Midazolam reverses salicylate-induced changes in brain-derived neurotrophic factor and arg3.1 expression: implications for tinnitus perception and auditory plasticity.

Panford-Walsh R, Singer W, Rüttiger L, Hadjab S, Tan J, Geisler HS, Zimmermann U, Köpschall I, Rohbock K, Vieljans A, Oestreicher E, Knipper M.

Mol Pharmacol. 2008 Sep;74(3):595-604. doi: 10.1124/mol.108.046375. Epub 2008 Jun 4.


Estrogen and the inner ear: megalin knockout mice suffer progressive hearing loss.

König O, Rüttiger L, Müller M, Zimmermann U, Erdmann B, Kalbacher H, Gross M, Knipper M.

FASEB J. 2008 Feb;22(2):410-7. Epub 2007 Sep 10.


Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence.

Bichelmeier U, Schmidt T, Hübener J, Boy J, Rüttiger L, Häbig K, Poths S, Bonin M, Knipper M, Schmidt WJ, Wilbertz J, Wolburg H, Laccone F, Riess O.

J Neurosci. 2007 Jul 11;27(28):7418-28.


Exposure setups for laboratory animals and volunteer studies using body-mounted antennas.

Bahr A, Adami C, Bolz T, Rennings A, Dorn H, Rüttiger L.

Radiat Prot Dosimetry. 2007;124(1):31-4. Epub 2007 Jun 26.


A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy.

Alavi MV, Bette S, Schimpf S, Schuettauf F, Schraermeyer U, Wehrl HF, Ruttiger L, Beck SC, Tonagel F, Pichler BJ, Knipper M, Peters T, Laufs J, Wissinger B.

Brain. 2007 Apr;130(Pt 4):1029-42. Epub 2007 Feb 21.


Tinnitus behavior and hearing function correlate with the reciprocal expression patterns of BDNF and Arg3.1/arc in auditory neurons following acoustic trauma.

Tan J, Rüttiger L, Panford-Walsh R, Singer W, Schulze H, Kilian SB, Hadjab S, Zimmermann U, Köpschall I, Rohbock K, Knipper M.

Neuroscience. 2007 Mar 16;145(2):715-26. Epub 2007 Feb 1.


Two classes of outer hair cells along the tonotopic axis of the cochlea.

Engel J, Braig C, Rüttiger L, Kuhn S, Zimmermann U, Blin N, Sausbier M, Kalbacher H, Münkner S, Rohbock K, Ruth P, Winter H, Knipper M.

Neuroscience. 2006 Dec;143(3):837-49. Epub 2006 Oct 30.


Deafness in LIMP2-deficient mice due to early loss of the potassium channel KCNQ1/KCNE1 in marginal cells of the stria vascularis.

Knipper M, Claussen C, Rüttiger L, Zimmermann U, Lüllmann-Rauch R, Eskelinen EL, Schröder J, Schwake M, Saftig P.

J Physiol. 2006 Oct 1;576(Pt 1):73-86. Epub 2006 Aug 10.

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