Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 15

1.

NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS.

Ouali Alami N, Schurr C, Olde Heuvel F, Tang L, Li Q, Tasdogan A, Kimbara A, Nettekoven M, Ottaviani G, Raposo C, Röver S, Rogers-Evans M, Rothenhäusler B, Ullmer C, Fingerle J, Grether U, Knuesel I, Boeckers TM, Ludolph A, Wirth T, Roselli F, Baumann B.

EMBO J. 2018 Aug 15;37(16). pii: e98697. doi: 10.15252/embj.201798697. Epub 2018 Jun 6.

2.

Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists as Potential Treatment for Inflammatory Kidney Diseases.

Nettekoven M, Adam JM, Bendels S, Bissantz C, Fingerle J, Grether U, Grüner S, Guba W, Kimbara A, Ottaviani G, Püllmann B, Rogers-Evans M, Röver S, Rothenhäusler B, Schmitt S, Schuler F, Schulz-Gasch T, Ullmer C.

ChemMedChem. 2016 Jan 19;11(2):179-89. doi: 10.1002/cmdc.201500218. Epub 2015 Jul 21.

PMID:
26228928
3.

6-Alkoxy-5-aryl-3-pyridinecarboxamides, a new series of bioavailable cannabinoid receptor type 1 (CB1) antagonists including peripherally selective compounds.

Röver S, Andjelkovic M, Bénardeau A, Chaput E, Guba W, Hebeisen P, Mohr S, Nettekoven M, Obst U, Richter WF, Ullmer C, Waldmeier P, Wright MB.

J Med Chem. 2013 Dec 27;56(24):9874-96. doi: 10.1021/jm4010708. Epub 2013 Nov 20.

PMID:
24175572
4.

Highly potent and selective cannabinoid receptor 2 agonists: initial hit optimization of an adamantyl hit series identified from high-through-put screening.

Nettekoven M, Fingerle J, Grether U, Grüner S, Kimbara A, Püllmann B, Rogers-Evans M, Röver S, Schuler F, Schulz-Gasch T, Ullmer C.

Bioorg Med Chem Lett. 2013 Mar 1;23(5):1177-81. doi: 10.1016/j.bmcl.2013.01.044. Epub 2013 Jan 23.

PMID:
23380378
5.

Pyrido pyrimidinones as selective agonists of the high affinity niacin receptor GPR109A: optimization of in vitro activity.

Peters JU, Kühne H, Dehmlow H, Grether U, Conte A, Hainzl D, Hertel C, Kratochwil NA, Otteneder M, Narquizian R, Panousis CG, Ricklin F, Röver S.

Bioorg Med Chem Lett. 2010 Sep 15;20(18):5426-30. doi: 10.1016/j.bmcl.2010.07.108. Epub 2010 Jul 29.

PMID:
20724150
6.

Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity.

Alig L, Alsenz J, Andjelkovic M, Bendels S, Bénardeau A, Bleicher K, Bourson A, David-Pierson P, Guba W, Hildbrand S, Kube D, Lübbers T, Mayweg AV, Narquizian R, Neidhart W, Nettekoven M, Plancher JM, Rocha C, Rogers-Evans M, Röver S, Schneider G, Taylor S, Waldmeier P.

J Med Chem. 2008 Apr 10;51(7):2115-27. doi: 10.1021/jm701487t. Epub 2008 Mar 13.

PMID:
18335976
7.

Identification of 4-methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles as 5-HT2C receptor agonists.

Röver S, Adams DR, Bénardeau A, Bentley JM, Bickerdike MJ, Bourson A, Cliffe IA, Coassolo P, Davidson JE, Dourish CT, Hebeisen P, Kennett GA, Knight AR, Malcolm CS, Mattei P, Misra A, Mizrahi J, Muller M, Porter RH, Richter H, Taylor S, Vickers SP.

Bioorg Med Chem Lett. 2005 Aug 1;15(15):3604-8.

PMID:
15975787
8.

Novel hexahydrospiro[piperidine-4,1'-pyrrolo[3,4-c]pyrroles]: highly selective small-molecule nociceptin/orphanin FQ receptor agonists.

Kolczewski S, Adam G, Cesura AM, Jenck F, Hennig M, Oberhauser T, Poli SM, Rössler F, Röver S, Wichmann J, Dautzenberg FM.

J Med Chem. 2003 Jan 16;46(2):255-64.

PMID:
12519064
9.

High-affinity, non-peptide agonists for the ORL1 (orphanin FQ/nociceptin) receptor.

Röver S, Adam G, Cesura AM, Galley G, Jenck F, Monsma FJ Jr, Wichmann J, Dautzenberg FM.

J Med Chem. 2000 Apr 6;43(7):1329-38.

PMID:
10753470
10.
11.

ORL1 receptor ligands: structure-activity relationships of 8-cycloalkyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-ones.

Röver S, Wichmann J, Jenck F, Adam G, Cesura AM.

Bioorg Med Chem Lett. 2000 Apr 17;10(8):831-4.

PMID:
10782696
12.

8-acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as orphanin FQ receptor agonists.

Wichmann J, Adam G, Röver S, Cesura AM, Dautzenberg FM, Jenck F.

Bioorg Med Chem Lett. 1999 Aug 16;9(16):2343-8.

PMID:
10476866
13.

Synthesis and biochemical evaluation of N-(4-phenylthiazol-2-yl)benzenesulfonamides as high-affinity inhibitors of kynurenine 3-hydroxylase.

Röver S, Cesura AM, Huguenin P, Kettler R, Szente A.

J Med Chem. 1997 Dec 19;40(26):4378-85.

PMID:
9435907
14.

Cloning and functional expression of human kynurenine 3-monooxygenase.

Alberati-Giani D, Cesura AM, Broger C, Warren WD, Röver S, Malherbe P.

FEBS Lett. 1997 Jun 30;410(2-3):407-12.

15.

Circadian rhythmic variations of the relative number of binucleated liver cells in rats.

Philippens KM, Röver S, Abicht J.

Prog Clin Biol Res. 1981;59C(00):99-108. No abstract available.

PMID:
7279967

Supplemental Content

Support Center