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Items: 1 to 50 of 153

1.

Synchronizing Protein Traffic to the Primary Cilium.

Stroukov W, Rösch A, Schwan C, Jeney A, Römer W, Thuenauer R.

Front Genet. 2019 Mar 8;10:163. doi: 10.3389/fgene.2019.00163. eCollection 2019.

2.

Glycan-decorated protocells: novel features for rebuilding cellular processes.

Omidvar R, Römer W.

Interface Focus. 2019 Apr 6;9(2):20180084. doi: 10.1098/rsfs.2018.0084. Epub 2019 Feb 15. Review.

PMID:
30842879
3.

Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins.

Wilhelm I, Levit-Zerdoun E, Jakob J, Villringer S, Frensch M, Übelhart R, Landi A, Müller P, Imberty A, Thuenauer R, Claudinon J, Jumaa H, Reth M, Eibel H, Hobeika E, Römer W.

Sci Signal. 2019 Mar 5;12(571). pii: eaao7194. doi: 10.1126/scisignal.aao7194.

PMID:
30837305
4.

Binding of SV40's Viral Capsid Protein VP1 to Its Glycosphingolipid Receptor GM1 Induces Negative Membrane Curvature: A Molecular Dynamics Study.

Kociurzynski R, Beck SD, Bouhon JB, Römer W, Knecht V.

Langmuir. 2019 Mar 5;35(9):3534-3544. doi: 10.1021/acs.langmuir.8b03765. Epub 2019 Feb 25.

PMID:
30802059
5.

Phytochrome-Based Extracellular Matrix with Reversibly Tunable Mechanical Properties.

Hörner M, Raute K, Hummel B, Madl J, Creusen G, Thomas OS, Christen EH, Hotz N, Gübeli RJ, Engesser R, Rebmann B, Lauer J, Rolauffs B, Timmer J, Schamel WWA, Pruszak J, Römer W, Zurbriggen MD, Friedrich C, Walther A, Minguet S, Sawarkar R, Weber W.

Adv Mater. 2019 Mar;31(12):e1806727. doi: 10.1002/adma.201806727. Epub 2019 Jan 27.

PMID:
30687975
6.

Six versus eight doses of rituximab in patients with aggressive B cell lymphoma receiving six cycles of CHOP: results from the "Positron Emission Tomography-Guided Therapy of Aggressive Non-Hodgkin Lymphomas" (PETAL) trial.

Hüttmann A, Rekowski J, Müller SP, Hertenstein B, Franzius C, Mesters R, Weckesser M, Kroschinsky F, Kotzerke J, Ganser A, Bengel FM, La Rosée P, Freesmeyer M, Höffkes HG, Hertel A, Behringer D, Prange-Krex G, Griesshammer M, Holzinger J, Wilop S, Krohn T, Raghavachar A, Maschmeyer G, Brink I, Schroers R, Gaska T, Bernhard H, Giagounidis A, Schütte J, Dienst A, Hautzel H, Naumann R, Klein A, Hahn D, Pöpperl G, Grube M, Marienhagen J, Schwarzer A, Kurch L, Höhler T, Steiniger H, Nückel H, Südhoff T, Römer W, Brinkmann M, Ose C, Alashkar F, Schmitz C, Dürig J, Hoelzer D, Jöckel KH, Klapper W, Dührsen U.

Ann Hematol. 2019 Apr;98(4):897-907. doi: 10.1007/s00277-018-3578-0. Epub 2019 Jan 4.

PMID:
30610279
7.

GUV-AP: multifunctional FIJI-based tool for quantitative image analysis of Giant Unilamellar Vesicles.

Sych T, Schubert T, Vauchelles R, Madl J, Omidvar R, Thuenauer R, Richert L, Mély Y, Römer W.

Bioinformatics. 2018 Nov 26. doi: 10.1093/bioinformatics/bty962. [Epub ahead of print]

PMID:
30475993
8.

Tailor-made Janus lectin with dual avidity assembles glycoconjugate multilayers and crosslinks protocells.

Ribeiro JP, Villringer S, Goyard D, Coche-Guerente L, Höferlin M, Renaudet O, Römer W, Imberty A.

Chem Sci. 2018 Aug 14;9(39):7634-7641. doi: 10.1039/c8sc02730g. eCollection 2018 Oct 21.

9.

Lipid self-assembly and lectin-induced reorganization of the plasma membrane.

Sych T, Mély Y, Römer W.

Philos Trans R Soc Lond B Biol Sci. 2018 May 26;373(1747). pii: 20170117. doi: 10.1098/rstb.2017.0117. Review.

10.

A microfluidic biochip for locally confined stimulation of cells within an epithelial monolayer.

Thuenauer R, Nicklaus S, Frensch M, Troendle K, Madl J, Römer W.

RSC Adv. 2018 Feb 19;8(14):7839-7846. doi: 10.1039/c7ra11943g.

11.

Molecular AFM imaging of Hsp70-1A association with dipalmitoyl phosphatidylserine reveals membrane blebbing in the presence of cholesterol.

Lamprecht C, Gehrmann M, Madl J, Römer W, Multhoff G, Ebner A.

Cell Stress Chaperones. 2018 Jul;23(4):673-683. doi: 10.1007/s12192-018-0879-0. Epub 2018 Feb 5.

12.

Lectin-mediated protocell crosslinking to mimic cell-cell junctions and adhesion.

Villringer S, Madl J, Sych T, Manner C, Imberty A, Römer W.

Sci Rep. 2018 Jan 31;8(1):1932. doi: 10.1038/s41598-018-20230-6.

13.

Dynein light chain 1 induces assembly of large Bim complexes on mitochondria that stabilize Mcl-1 and regulate apoptosis.

Singh PK, Roukounakis A, Frank DO, Kirschnek S, Das KK, Neumann S, Madl J, Römer W, Zorzin C, Borner C, Haimovici A, Garcia-Saez A, Weber A, Häcker G.

Genes Dev. 2017 Sep 1;31(17):1754-1769. doi: 10.1101/gad.302497.117.

14.

Dynamic Cooperative Glycan Assembly Blocks the Binding of Bacterial Lectins to Epithelial Cells.

Machida T, Novoa A, Gillon É, Zheng S, Claudinon J, Eierhoff T, Imberty A, Römer W, Winssinger N.

Angew Chem Int Ed Engl. 2017 Jun 6;56(24):6762-6766. doi: 10.1002/anie.201700813. Epub 2017 May 15.

PMID:
28504473
15.

Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-β1 expression.

Andrlová H, Mastroianni J, Madl J, Kern JS, Melchinger W, Dierbach H, Wernet F, Follo M, Technau-Hafsi K, Has C, Rao Mittapalli V, Idzko M, Herr R, Brummer T, Ungefroren H, Busch H, Boerries M, Narr A, Ihorst G, Vennin C, Schmitt-Graeff A, Minguet S, Timpson P, Duyster J, Meiss F, Römer W, Zeiser R.

Oncotarget. 2017 Jun 27;8(26):42901-42916. doi: 10.18632/oncotarget.17160.

16.

The Pseudomonas aeruginosa lectin LecA triggers host cell signalling by glycosphingolipid-dependent phosphorylation of the adaptor protein CrkII.

Zheng S, Eierhoff T, Aigal S, Brandel A, Thuenauer R, de Bentzmann S, Imberty A, Römer W.

Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1236-1245. doi: 10.1016/j.bbamcr.2017.04.005. Epub 2017 Apr 17.

17.

Gb3-binding lectins as potential carriers for transcellular drug delivery.

Müller SK, Wilhelm I, Schubert T, Zittlau K, Imberty A, Madl J, Eierhoff T, Thuenauer R, Römer W.

Expert Opin Drug Deliv. 2017 Feb;14(2):141-153. doi: 10.1080/17425247.2017.1266327. Epub 2016 Dec 16.

PMID:
27935765
18.

Pathways of protein and lipid receptor-mediated transcytosis in drug delivery.

Thuenauer R, Müller SK, Römer W.

Expert Opin Drug Deliv. 2017 Mar;14(3):341-351. doi: 10.1080/17425247.2016.1220364. Epub 2016 Aug 16. Review.

PMID:
27500785
19.

Synthesis of Cholesterol-Substituted Glycopeptides for Tailor-Made Glycocalyxification of Artificial Membrane Systems.

Stuhr-Hansen N, Madl J, Villringer S, Aili U, Römer W, Blixt O.

Chembiochem. 2016 Aug 3;17(15):1403-6. doi: 10.1002/cbic.201600258. Epub 2016 Jun 17.

PMID:
27168414
20.

Pseudomonas aeruginosa lectin LecB inhibits tissue repair processes by triggering β-catenin degradation.

Cott C, Thuenauer R, Landi A, Kühn K, Juillot S, Imberty A, Madl J, Eierhoff T, Römer W.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1106-18. doi: 10.1016/j.bbamcr.2016.02.004. Epub 2016 Feb 6.

21.

Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression.

Mittapalli VR, Madl J, Löffek S, Kiritsi D, Kern JS, Römer W, Nyström A, Bruckner-Tuderman L.

Cancer Res. 2016 Feb 15;76(4):940-51. doi: 10.1158/0008-5472.CAN-15-1348. Epub 2015 Dec 16.

22.

Signalling to the nucleus under the control of light and small molecules.

Juillot S, Beyer HM, Madl J, Weber W, Zurbriggen MD, Römer W.

Mol Biosyst. 2016 Feb;12(2):345-9. doi: 10.1039/c5mb00763a.

PMID:
26672971
23.
24.

Uptake of Marasmius oreades agglutinin disrupts integrin-dependent cell adhesion.

Juillot S, Cott C, Madl J, Claudinon J, van der Velden NS, Künzler M, Thuenauer R, Römer W.

Biochim Biophys Acta. 2016 Feb;1860(2):392-401. doi: 10.1016/j.bbagen.2015.11.002. Epub 2015 Nov 10.

25.

Considering autophagy, β-Catenin and E-Cadherin as innovative therapy aspects in AML.

Kühn K, Römer W.

Cell Death Dis. 2015 Oct 29;6:e1950. doi: 10.1038/cddis.2015.314. No abstract available.

26.

How synthetic membrane systems contribute to the understanding of lipid-driven endocytosis.

Schubert T, Römer W.

Biochim Biophys Acta. 2015 Nov;1853(11 Pt B):2992-3005. doi: 10.1016/j.bbamcr.2015.07.014. Epub 2015 Jul 26. Review.

27.

2-Hydroxy Fatty Acid Enantiomers of Gb3 Impact Shiga Toxin Binding and Membrane Organization.

Schütte OM, Patalag LJ, Weber LM, Ries A, Römer W, Werz DB, Steinem C.

Biophys J. 2015 Jun 16;108(12):2775-8. doi: 10.1016/j.bpj.2015.05.009.

28.

A first step toward liposome-mediated intracellular bacteriophage therapy.

Nieth A, Verseux C, Barnert S, Süss R, Römer W.

Expert Opin Drug Deliv. 2015;12(9):1411-24. doi: 10.1517/17425247.2015.1043125. Epub 2015 May 2.

PMID:
25937143
29.

Red Light-Regulated Reversible Nuclear Localization of Proteins in Mammalian Cells and Zebrafish.

Beyer HM, Juillot S, Herbst K, Samodelov SL, Müller K, Schamel WW, Römer W, Schäfer E, Nagy F, Strähle U, Weber W, Zurbriggen MD.

ACS Synth Biol. 2015 Sep 18;4(9):951-8. doi: 10.1021/acssynbio.5b00004. Epub 2015 Mar 30.

PMID:
25803699
30.

Lectins from opportunistic bacteria interact with acquired variable-region glycans of surface immunoglobulin in follicular lymphoma.

Schneider D, Dühren-von Minden M, Alkhatib A, Setz C, van Bergen CA, Benkißer-Petersen M, Wilhelm I, Villringer S, Krysov S, Packham G, Zirlik K, Römer W, Buske C, Stevenson FK, Veelken H, Jumaa H.

Blood. 2015 May 21;125(21):3287-96. doi: 10.1182/blood-2014-11-609404. Epub 2015 Mar 17.

31.

Aquaporin 5 expression in mouse mammary gland cells is not driven by promoter methylation.

Arbeithuber B, Thuenauer R, Gravogl Y, Balogi Z, Römer W, Sonnleitner A, Tiemann-Boege I.

Biomed Res Int. 2015;2015:460598. doi: 10.1155/2015/460598. Epub 2015 Feb 12.

32.

The innate defense antimicrobial peptides hBD3 and RNase7 are induced in human umbilical vein endothelial cells by classical inflammatory cytokines but not Th17 cytokines.

Burgey C, Kern WV, Römer W, Sakinc T, Rieg S.

Microbes Infect. 2015 May;17(5):353-9. doi: 10.1016/j.micinf.2015.01.005. Epub 2015 Jan 28.

PMID:
25637949
33.

The interplay of autophagy and β-Catenin signaling regulates differentiation in acute myeloid leukemia.

Kühn K, Cott C, Bohler S, Aigal S, Zheng S, Villringer S, Imberty A, Claudinon J, Römer W.

Cell Death Discov. 2015 Sep 21;1:15031. doi: 10.1038/cddiscovery.2015.31. eCollection 2015.

34.

Skin cancer induced by natural UV-radiation as an occupational disease—requirements for its notification and recognition.

Diepgen TL, Brandenburg S, Aberer W, Bauer A, Drexler H, Fartasch M, John SM, Krohn S, Palfner S, Römer W, Schuhmacher-Stock U, Elsner P.

J Dtsch Dermatol Ges. 2014 Dec;12(12):1102-6. doi: 10.1111/ddg.12537. Review. English, German.

PMID:
25482691
35.

Plasma membrane reorganization: A glycolipid gateway for microbes.

Aigal S, Claudinon J, Römer W.

Biochim Biophys Acta. 2015 Apr;1853(4):858-71. doi: 10.1016/j.bbamcr.2014.11.014. Epub 2014 Nov 18. Review.

36.

A lipid zipper triggers bacterial invasion.

Eierhoff T, Bastian B, Thuenauer R, Madl J, Audfray A, Aigal S, Juillot S, Rydell GE, Müller S, de Bentzmann S, Imberty A, Fleck C, Römer W.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12895-900. doi: 10.1073/pnas.1402637111. Epub 2014 Aug 18.

37.

A LecA ligand identified from a galactoside-conjugate array inhibits host cell invasion by Pseudomonas aeruginosa.

Novoa A, Eierhoff T, Topin J, Varrot A, Barluenga S, Imberty A, Römer W, Winssinger N.

Angew Chem Int Ed Engl. 2014 Aug 18;53(34):8885-9. doi: 10.1002/anie.201402831. Epub 2014 Jul 7.

PMID:
25044671
38.

Membrane deformation by neolectins with engineered glycolipid binding sites.

Arnaud J, Tröndle K, Claudinon J, Audfray A, Varrot A, Römer W, Imberty A.

Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9267-70. doi: 10.1002/anie.201404568. Epub 2014 Jul 7.

PMID:
25044646
39.

Metabolic pathway monitoring of phenalinolactone biosynthesis from Streptomyces sp. Tü6071 by liquid chromatography/mass spectrometry coupling.

Kiske C, Erxleben A, Lucas X, Willmann L, Klementz D, Günther S, Römer W, Kammerer B.

Rapid Commun Mass Spectrom. 2014 Jul 15;28(13):1459-67. doi: 10.1002/rcm.6920.

PMID:
24861595
40.

[Fever, atrial fibrillation, and angina pectoris in a 58-year-old man].

Groebner M, Südhoff T, Doering M, Kirmayer M, Nitsch T, Prügl L, Römer W, Wolf H, Tacke J, Massoudy P, Nüsse T, Elsner D.

Internist (Berl). 2014 May;55(5):595-600. doi: 10.1007/s00108-014-3477-y. German.

PMID:
24770978
41.

Rab12 localizes to Shiga toxin-induced plasma membrane invaginations and controls toxin transport.

Rydell GE, Renard HF, Garcia-Castillo MD, Dingli F, Loew D, Lamaze C, Römer W, Johannes L.

Traffic. 2014 Jul;15(7):772-87. doi: 10.1111/tra.12173. Epub 2014 May 5.

42.

Sphingosine-1-phosphate receptors control B-cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia, and multiple sclerosis.

Sic H, Kraus H, Madl J, Flittner KA, von Münchow AL, Pieper K, Rizzi M, Kienzler AK, Ayata K, Rauer S, Kleuser B, Salzer U, Burger M, Zirlik K, Lougaris V, Plebani A, Römer W, Loeffler C, Scaramuzza S, Villa A, Noguchi E, Grimbacher B, Eibel H.

J Allergy Clin Immunol. 2014 Aug;134(2):420-8. doi: 10.1016/j.jaci.2014.01.037. Epub 2014 Mar 26.

PMID:
24679343
43.

Induced phagocytic particle uptake into a giant unilamellar vesicle.

Meinel A, Tränkle B, Römer W, Rohrbach A.

Soft Matter. 2014 May 28;10(20):3667-78. doi: 10.1039/c3sm52964a. Epub 2014 Mar 27.

PMID:
24676395
44.

Microfluidic approaches for epithelial cell layer culture and characterisation.

Thuenauer R, Rodriguez-Boulan E, Römer W.

Analyst. 2014 Jul 7;139(13):3206-18. doi: 10.1039/c4an00056k. Review.

45.

Four-dimensional live imaging of apical biosynthetic trafficking reveals a post-Golgi sorting role of apical endosomal intermediates.

Thuenauer R, Hsu YC, Carvajal-Gonzalez JM, Deborde S, Chuang JZ, Römer W, Sonnleitner A, Rodriguez-Boulan E, Sung CH.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4127-32. doi: 10.1073/pnas.1304168111. Epub 2014 Mar 3.

46.

Reduction of lectin valency drastically changes glycolipid dynamics in membranes but not surface avidity.

Arnaud J, Claudinon J, Tröndle K, Trovaslet M, Larson G, Thomas A, Varrot A, Römer W, Imberty A, Audfray A.

ACS Chem Biol. 2013 Sep 20;8(9):1918-24. doi: 10.1021/cb400254b. Epub 2013 Jul 23.

PMID:
23855446
47.

Human GII.4 norovirus VLP induces membrane invaginations on giant unilamellar vesicles containing secretor gene dependent α1,2-fucosylated glycosphingolipids.

Rydell GE, Svensson L, Larson G, Johannes L, Römer W.

Biochim Biophys Acta. 2013 Aug;1828(8):1840-5. doi: 10.1016/j.bbamem.2013.03.016. Epub 2013 Mar 23.

48.

Photoreductive uncaging of fluorophore in response to protein oligomers by templated reaction in vitro and in cellulo.

Sadhu KK, Eierhoff T, Römer W, Winssinger N.

J Am Chem Soc. 2012 Dec 12;134(49):20013-6. doi: 10.1021/ja310171s. Epub 2012 Nov 30.

PMID:
23186060
49.

[SPECT/CT - Technical aspects and optimization possibilities].

Römer W.

Radiologe. 2012 Jul;52(7):608-14. doi: 10.1007/s00117-011-2268-x. German.

PMID:
22699407
50.

Fucose-binding lectin from opportunistic pathogen Burkholderia ambifaria binds to both plant and human oligosaccharidic epitopes.

Audfray A, Claudinon J, Abounit S, Ruvoën-Clouet N, Larson G, Smith DF, Wimmerová M, Le Pendu J, Römer W, Varrot A, Imberty A.

J Biol Chem. 2012 Feb 3;287(6):4335-47. doi: 10.1074/jbc.M111.314831. Epub 2011 Dec 14.

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